Orthopaedics - Arkan Sayed-Noor
Arkan Sayed-Noor’s research group in trauma and orthopaedic surgery conducts a wide range of clinical and registry-based research projects at the Department of Clinical Science and Education, Södersjukhuset at Karolinska Institutet and Södersjukhuset.
These projects include joint replacement surgery, fracture surgery especially in osteoporosis-related fractures, soft-tissue injuries of the knee, spine surgery and hand surgery. The main aim of the projects is to evaluate the factors that influence the functional outcome and quality of life in order to improve the outcome in these conditions.
Research group leader
Joint replacement surgery
Each year thousands of Swedish patients are operated with joint replacement of the hip, knee or shoulder. The commonest two causes for these surgeries are osteoarthritis and fractures involving these joints. The research group aims to study how patient’s factors such age, gender, weight, medical diseases, functional status would affect the functional outcome, quality of life and perioperative complications. One project will also evaluate the outcome of a new type of shoulder replacement while in another project who work-related factors would influence the incidence of different types of surgical interventions in the upper limbs.
More information: Arkan Sayed-Noor MD, PhD, Professor
Wrist fractures are common and the treatment is controversial. The interpretation of the outcome of the various treatment procedures is complicated by the wide range of patient expectation, from the young and active to the sedentary and non-active patient.
The research group is running three randomized trials to compare different fixation techniques and different anesthetic methods. The patients are followed, evaluated and compared utilizing modern Health-Related Quality of Life (HRQOL) instruments together with clinical outcome measures.
More information: Cecilia Mellstrand-Navarro, MD, PhD, Johanna Rundgren, MD, PhD, Hanna Südow, MD, PhD student.
Recovery after whiplash injuries of the neck
The associations between genetic factors, insurance company involvement and radiological factors and the risk of non-recovery after trauma are poorly investigated nor understood. In several studies on patient cohorts with traffic accidents, the research group investigates the relationship between different factors associated with recovery after injuries. The aims are to identify people with acute whiplash injuries who are at risk for non-recovery. The group is also performing a RCT to investigate whether an intervention in the form of an information film can result in better recovery.
More information: Eric Rydman, MD, PhD
Anterior cruciate ligament (ACL) reconstruction
ACL injury is a common sports related injury where the patient will experience instability of the knee joint which may prevent sporting activities. ACL construction is a common procedure to remedy this.
The research group runs several studies focusing on the methods and timing of ACL reconstruction as well on osteoarthritis following ACL-reconstruction.
More information: Björn Barenius, MD, PhD, Karl Eriksson, MD, PhD, Ass. professor
Association between cervical degeneration and self-perceived non-recovery after whiplash injury.
Rydman E, Kasina P, Ponzer S, Järnbert-Pettersson H
Spine J 2019 Aug;():
Regional or General Anesthesia in the Surgical Treatment of Distal Radial Fractures: A Randomized Clinical Trial.
Rundgren J, Mellstrand Navarro C, Ponzer S, Regberg A, Serenius S, Enocson A
J Bone Joint Surg Am 2019 Jul;101(13):1168-1176
Nonoperative Treatment Compared with Volar Locking Plate Fixation for Dorsally Displaced Distal Radial Fractures in the Elderly: A Randomized Controlled Trial.
Saving J, Severin Wahlgren S, Olsson K, Enocson A, Ponzer S, Sköldenberg O, et al
J Bone Joint Surg Am 2019 Jun;101(11):961-969
Quantifying cervical spondylosis: reliability testing of a coherent CT-based scoring system.
Rydman E, Bankler S, Ponzer S, Järnbert-Pettersson H
BMC Med Imaging 2019 05;19(1):45
Distal radius fractures-Regional variation in treatment regimens.
Saving J, Ponzer S, Enocson A, Mellstrand Navarro C
PLoS ONE 2018 ;13(11):e0207702
External Fixation Versus Volar Locking Plate for Unstable Dorsally Displaced Distal Radius Fractures-A 3-Year Follow-Up of a Randomized Controlled Study.
Saving J, Enocson A, Ponzer S, Mellstrand Navarro C
J Hand Surg Am 2019 Jan;44(1):18-26
Long-term follow-up of whiplash injuries reported to insurance companies: a cohort study on patient-reported outcomes and impact of financial compensation.
Rydman E, Ponzer S, Brisson R, Ottosson C, Pettersson-Järnbert H
Eur Spine J 2018 06;27(6):1255-1261
COMT genotype and non-recovery after a whiplash injury in a Northern European population.
Rydman E, Comasco E, Pettersson H, Oreland L, Ponzer S, Ottosson C
BMC Musculoskelet Disord 2017 Dec;18(1):507
Patients with head trauma: A study on initial prehospital assessment and care.
Rubenson Wahlin R, Lindström V, Ponzer S, Vicente V
Int Emerg Nurs 2018 01;36():51-55