Eric Westman

About me
Publications
Grants
CV
Public outreach and news

About me

I have an engineering background from the Royal Institute of Technology (KTH) in Stockholm and I obtained my PhD in 2009 at Karolinska Institutet (KI). I did my postdoc at the Institute of Psychiatry, King’s College London and I became an associate professor in 2014 at KI. I am the head of the Division for Clinical Geriatrics and I have my own research group within the division. Currently, I am also acting/vice head of the Department of Neurobiology, Care Sciences and Society.

Research

The aim of my research is to combine different biomarkers looking at patterns of disease. Due to the complexity and heterogeneity of Alzheimer’s disease (AD) and other neurodegenerative disorder, using one biomarker is probably not enough. The focus of my research has long been on structural magnetic resonance imaging investigating patterns of atrophy, but my research extends to other imaging modalities such as MR-spectroscopy, resting state fMRI, MR-diffusion, positron emission tomography (PET) and computer tomography (CT) etc. Further, the combination of neuroimaging biomarkers with CSF and blood markers is of great interest. The need for advanced statistical tools is important when combing large amounts of data from multiple neuroimaging modalities. Combining multiple biomarkers with multivariate tools will hopefully aid in diagnosing the disease in an early stage which is important when effective treatments for AD can be administered, monitor disease progression, target the right population for clinical trial and understand the underlying mechanisms of different diseases.

Articles

Article: COMPUTERS IN BIOLOGY AND MEDICINE. 2024;182:109190
Frontoparietal atrophy trajectories in cognitively unimpaired elderly individuals using longitudinal Bayesian clustering.
Lorenzon G; Poulakis K; Mohanty R; Kivipelto M; Eriksdotter M; Ferreira D; Westman E; Alzheimer's Disease Neuroimaging Initiative
Article: NATURE GENETICS. 2024;56(11):2333-2344
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
García-Marín LM; Campos AI; Diaz-Torres S; Rabinowitz JA; Ceja Z; Mitchell BL; Grasby KL; Thorp JG; Agartz I; Alhusaini S; Ames D; Amouyel P; Andreassen OA; Arfanakis K; Arias-Vasquez A; Armstrong NJ; Athanasiu L; Bastin ME; Beiser AS; Bennett DA; Bis JC; Boks MPM; Boomsma DI; Brodaty H; Brouwer RM; Buitelaar JK; Burkhardt R; Cahn W; Calhoun VD; Carmichael OT; Chakravarty M; Chen Q; Ching CRK; Cichon S; Crespo-Facorro B; Crivello F; Dale AM; Smith GD; de Geus EJC; De Jager PL; de Zubicaray GI; Debette S; DeCarli C; Depondt C; Desrivières S; Djurovic S; Ehrlich S; Erk S; Espeseth T; Fernández G; Filippi I; Fisher SE; Fleischman DA; Fletcher E; Fornage M; Forstner AJ; Francks C; Franke B; Ge T; Goldman AL; Grabe HJ; Green RC; Grimm O; Groenewold NA; Gruber O; Gudnason V; Håberg AK; Haukvik UK; Heinz A; Hibar DP; Hilal S; Himali JJ; Ho B-C; Hoehn DF; Hoekstra PJ; Hofer E; Hoffmann W; Holmes AJ; Homuth G; Hosten N; Ikram MK; Ipser JC; Jack CR; Jahanshad N; Jönsson EG; Kahn RS; Kanai R; Klein M; Knol MJ; Launer LJ; Lawrie SM; Hellard SL; Lee PH; Lemaître H; Li S; Liewald DCM; Lin H; Longstreth WT; Lopez OL; Luciano M; Maillard P; Marquand AF; Martin NG; Martinot J-L; Mather KA; Mattay VS; McMahon KL; Mecocci P; Melle I; Meyer-Lindenberg A; Mirza-Schreiber N; Milaneschi Y; Mosley TH; Mühleisen TW; Müller-Myhsok B; Maniega SM; Nauck M; Nho K; Niessen WJ; Nöthen MM; Nyquist PA; Oosterlaan J; Pandolfo M; Paus T; Pausova Z; Penninx BWJH; Pike GB; Psaty BM; Pütz B; Reppermund S; Rietschel MD; Risacher SL; Romanczuk-Seiferth N; Romero-Garcia R; Roshchupkin GV; Rotter JI; Sachdev PS; Sämann PG; Saremi A; Sargurupremraj M; Saykin AJ; Schmaal L; Schmidt H; Schmidt R; Schofield PR; Scholz M; Schumann G; Schwarz E; Shen L; Shin J; Sisodiya SM; Smith AV; Smoller JW; Soininen HS; Steen VM; Stein DJ; Stein JL; Thomopoulos SI; Toga AW; Tordesillas-Gutiérrez D; Trollor JN; Valdes-Hernandez MC; van T Ent D; van Bokhoven H; van der Meer D; van der Wee NJA; Vázquez-Bourgon J; Veltman DJ; Vernooij MW; Villringer A; Vinke LN; Völzke H; Walter H; Wardlaw JM; Weinberger DR; Weiner MW; Wen W; Westlye LT; Westman E; White T; Witte AV; Wolf C; Yang J; Zwiers MP; Ikram MA; Seshadri S; Thompson PM; Satizabal CL; Medland SE; Rentería ME
Article: ALZHEIMER'S AND DEMENTIA. 2024;20(10):6740-6754
Long-term effects of cholinesterase inhibitors and memantine on cognitive decline, cardiovascular events, and mortality in dementia with Lewy bodies: An up to 10-year follow-up study
Xu H; Habich A; Ferreira D; Elisabet L; Westman E; Eriksdotter M
Article: BRAIN COMMUNICATIONS. 2024;6(5):fcae290
Cerebrovascular and Alzheimer's disease biomarkers in dementia with Lewy bodies and other dementias
Rennie A; Ekman U; Shams S; Ryden L; Samuelsson J; Zettergren A; Kern S; Oppedal K; Blanc F; Hort J; Garcia-Ptacek S; Antonini A; Lemstra AW; Padovani A; Kramberger MG; Rektorova I; Walker Z; Snaedal J; Pardini M; Taylor J-P; Bonanni L; Granberg T; Aarsland D; Skoog I; Wahlund L-O; Kivipelto M; Westman E; Ferreira D
Article: MOVEMENT DISORDERS CLINICAL PRACTICE. 2024;11(11):1410-1420
Exploring Responsiveness to Highly Challenging Balance and Gait Training in Parkinson's Disease
Albrecht F; Johansson H; Poulakis K; Westman E; Hagstromer M; Franzen E
Article: NPJ PARKINSON'S DISEASE. 2024;10(1):159
MRI subtypes in Parkinson's disease across diverse populations and clustering approaches
Inguanzo A; Mohanty R; Poulakis K; Ferreira D; Segura B; Albrecht F; Muehlboeck J-S; Granberg T; Sjostrom H; Svenningsson P; Franzen E; Junque C; Westman E
Article: CLINICAL NEUROPSYCHOLOGIST. 2024;:1-15
Methods for assessment of rey auditory verbal learning test performance in memory clinic patients and healthy adults - at the cross-roads of learning theory and clinical utility
Almkvist O; Rennie A; Westman E; Wallert J; Ekman U
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2024;16(1):153
Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns
Lerch O; Ferreira D; Stomrud E; van Westen D; Tideman P; Palmqvist S; Mattsson-Carlgren N; Hort J; Hansson O; Westman E
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2024;16(1):147
Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer's disease: Multimodal Preventive Trial for Alzheimer's Disease (MIND-AD_mini)
Levak N; Lehtisalo J; Thunborg C; Westman E; Andersen P; Andrieu S; Broersen LM; Coley N; Hartmann T; Irving GF; Mangialasche F; Ngandu T; Pantel J; Rosenberg A; Sindi S; Soininen H; Solomon A; Wang R; Kivipelto M
Article: MEDRXIV. 2024;:2024.06.23.24309144
Assessing CT-based Volumetric Analysis via Transfer Learning with MRI and Manual Labels for Idiopathic Normal Pressure Hydrocephalus.
Srikrishna M; Seo W; Zettergren A; Kern S; Cantré D; Gessler F; Sotoudeh H; Seidlitz J; Bernstock JD; Wahlund L-O; Westman E; Skoog I; Virhammar J; Fällmar D; Schöll M
Article: NEUROLOGY. 2024;102(9):e209402
Proportion of Community-Dwelling Individuals Older Than 70 Years Eligible for Lecanemab Initiation
Dittrich A; Westman E; Shams S; Skillbaeck T; Zetterberg H; Blennow K; Zettergren A; Skoog I; Kern S
Article: NPJ DIGITAL MEDICINE. 2024;7(1):110
Constructing personalized characterizations of structural brain aberrations in patients with dementia using explainable artificial intelligence
Leonardsen EH; Persson K; Grodem E; Dinsdale N; Schellhorn T; Roe JM; Vidal-Pineiro D; Sorensen O; Kaufmann T; Westman E; Marquand A; Selbaek G; Andreassen OA; Wolfers T; Westlye LT; Wang Y
Article: NPJ PARKINSON'S DISEASE. 2024;10(1):84
Grey matter networks in women and men with dementia with Lewy bodies
Habich A; Oltra J; Schwarz CG; Przybelski SA; Oppedal K; Inguanzo A; Blanc F; Lemstra AW; Hort J; Westman E; Segura B; Junque C; Lowe VJ; Boeve BF; Aarsland D; Dierks T; Kantarci K; Ferreira D
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2024;25(4):664-670.e3
Temporal Muscle Thickness: A Practical Approximation for Assessing Muscle Mass in Older Adults
Borda MG; Baldera JP; Samuelsson J; Zettergren A; Ryden L; Westman E; Perez-Zepeda MU; Kern S; Venegas LC; Duque G; Skoog I; Aarsland D
Article: PARKINSONISM AND RELATED DISORDERS. 2024;121:106047
Putaminal T1/T2-weighted ratio is increased in PSP compared to PD and healthy controls, a multi-cohort study
Sjostrom H; van Westen D; Hall S; Tjerkaski J; Westman E; Muehlboeck S; Hansson O; Svenningsson P; Granberg T
Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2024;274(2):363-373
Effects of current alcohol use on brain volume among older adults in the Gothenburg H70 Birth Cohort study 2014-16
Lindberg O; Ahlner F; Tsevis T; Pereira JB; Westman E; Skoog I; Wahlund L-O
Article: ALZHEIMER'S AND DEMENTIA. 2024;20(3):1815-1826
Sex differences in brain atrophy in dementia with Lewy bodies
Oltra J; Habich A; Schwarz CG; Nedelska Z; Przybelski SA; Inguanzo A; Diaz-Galvan P; Lowe VJ; Oppedal K; Gonzalez MC; Philippi N; Blanc F; Barkhof F; Lemstra AW; Hort J; Padovani A; Rektorova I; Bonanni L; Massa F; Kramberger MG; Taylor J-P; Snaedal JG; Walker Z; Antonini A; Dierks T; Segura B; Junque C; Westman E; Boeve BF; Aarsland D; Kantarci K; Ferreira D
Article: HUMAN BRAIN MAPPING. 2024;45(4):e26618
In vivo microstructural heterogeneity of white matter and cognitive correlates in aging using tissue compositional analysis of diffusion magnetic resonance imaging
Badji A; Cedres N; Muehlboeck J-S; Khan W; Dhollander T; Barroso J; Ferreira D; Westman E
Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2024;79(2):glad216
Biomarkers of Alzheimer's Disease and Cerebrovascular Disease in Relation to Depressive Symptomatology in Individuals With Subjective Cognitive Decline
Zapater-Fajari M; Diaz-Galvan P; Cedres N; Sterner TR; Ryden L; Sacuiu S; Waern M; Zettergren A; Zetterberg H; Blennow K; Kern S; Hidalgo V; Salvador A; Westman E; Skoog I; Ferreira D
Article: JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE. 2024;15(1):189-197
Using magnetic resonance imaging to measure head muscles: An innovative method to opportunistically determine muscle mass and detect sarcopenia
Borda MG; Duque G; Perez-Zepeda MU; Baldera JP; Westman E; Zettergren A; Samuelsson J; Kern S; Ryden L; Skoog I; Aarsland D
Article: CEREBRAL CORTEX. 2024;34(2):bhad542
Dynamic multilayer functional connectivity detects preclinical and clinical Alzheimer's disease
Canal-Garcia A; Vereb D; Mijalkov M; Westman E; Volpe G; Pereira JB
Article: NEUROLOGY. 2024;102(2):e208037
Prevalence of Possible Idiopathic Normal Pressure Hydrocephalus in Sweden A Population-Based MRI Study in 791 70-Year-Old Participants
Constantinescu C; Wikkelso C; Westman E; Ziegelitz D; Jaraj D; Ryden L; Skoog I; Tullberg M
Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2024;16(1):e12556
Association of CSF biomarkers with MRI brain changes in Alzheimer's disease
Seidu NM; Kern S; Sacuiu S; Sterner TR; Blennow K; Zetterberg H; Lindberg O; Ferreira D; Westman E; Zettergren A; Skoog I
Article: FRONTIERS IN NEUROSCIENCE. 2024;18:1355695
Multi-pathological contributions toward atrophy patterns in the Alzheimer's disease continuum
Mohanty R; Ferreira D; Westman E
Article: ALZHEIMER'S AND DEMENTIA. 2024;20(1):629-640
CT-based volumetric measures obtained through deep learning: Association with biomarkers of neurodegeneration
Srikrishna M; Ashton NJ; Moscoso A; Pereira JB; Heckemann RA; van Westen D; Volpe G; Simren J; Zettergren A; Kern S; Wahlund L-O; Gyanwali B; Hilal S; Ruifen JC; Zetterberg H; Blennow K; Westman E; Chen C; Skoog I; Scholl M
Article: HUMAN BRAIN MAPPING. 2023;44(18):6459-6470
Lifelong olfactory deprivation-dependent cortical reorganization restricted to orbitofrontal cortex
Peter MG; Darki F; Thunell E; Martensson G; Postma EM; Boesveldt S; Westman E; Lundstrom JN
Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2023;455:122806
Predicting amyloid-PET status in a memory clinic: The role of the novel antero-posterior index and visual rating scales
Zilioli A; Misirocchi F; Pancaldi B; Mutti C; Ganazzoli C; Morelli N; Pellegrini FF; Messa G; Scarlattei M; Mohanty R; Ruffini L; Westman E; Spallazzi M
Article: JOURNAL OF ORAL REHABILITATION. 2023;50(12):1422-1431
White matter abnormalities mediate the association between masticatory dysfunction and cognition among older adults
Hedberg L; Kumar A; Skott P; Smedberg J-I; Seiger A; Sandborgh-Englund G; Nordin LE; Kareholt I; Tzortzakakis A; Westman E; Trulsson M; Ekman U
Article: ALZHEIMER'S AND DEMENTIA. 2023;19(10):4629-4640
Associations between dietary patterns and dementia-related neuroimaging markers
Samuelsson J; Marseglia A; Lindberg O; Westman E; Pereira JB; Shams S; Kern S; Ahlner F; Rothenberg E; Skoog I; Zettergren A
Article: NEUROBIOLOGY OF AGING. 2023;129:41-49
Comparing three neuropsychological subgrouping approaches in subjective and mild cognitive impairment from a naturalistic multicenter study
Rennie A; Ekman U; Wallert J; Muehlboeck J-S; Eriksdotter M; Wahlund L-O; Ferreira D; Westman E
Article: NEUROLOGY. 2023;101(3):e277-e288
Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration The H70 Birth Cohort Study in Gothenburg
Dittrich A; Ashton NJJ; Zetterberg H; Blennow K; Zettergren A; Simren J; Skillback T; Shams S; Machado A; Westman E; Scholl M; Skoog I; Kern S
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2023;15(1):117
Differential response to donepezil in MRI subtypes of mild cognitive impairment
Diaz-Galvan P; Lorenzon G; Mohanty R; Martensson G; Cavedo E; Lista S; Vergallo A; Kantarci K; Hampel H; Dubois B; Grothe MJ; Ferreira D; Westman E
Article: BRAIN. 2023;146(5):2075-2088
Cholinergic white matter pathways along the Alzheimer's disease continuum
Nemy M; Dyrba M; Brosseron F; Buerger K; Dechent P; Dobisch L; Ewers M; Fliessbach K; Glanz W; Goerss D; Heneka MT; Hetzer S; Incesoy EI; Janowitz D; Kilimann I; Laske C; Maier F; Munk MH; Perneczky R; Peters O; Preis L; Priller J; Rauchmann B-S; Roeske S; Roy N; Scheffler K; Schneider A; Schott BH; Spottke A; Spruth EJ; Wagner M; Wiltfang J; Yakupov R; Eriksdotter M; Westman E; Stepankova O; Vyslouzilova L; Duezel E; Jessen F; Teipel SJ; Ferreira D
Article: ANNALS OF NEUROLOGY. 2023;93(4):844-855
Social Health and Cognitive Change in Old Age: Role of Brain Reserve
Marseglia A; Kalpouzos G; Laukka EJ; Maddock J; Patalay P; Wang H-X; Backman L; Westman E; Welmer A-K; Dekhtyar S
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2023;92(2):605-614
The Association Between Temporal Atrophy and Episodic Memory Is Moderated by Education in a Multi-Center Memory Clinic Sample
Gyllenhammar M; Rennie A; Padilla DF; Wallert J; Rydstrom A; Wahlund L-O; Eriksdotter M; Westman E; Ekman U
Article: HUMAN BRAIN MAPPING. 2023;44(4):1289-1308
Fast three-dimensional image generation for healthy brain aging using diffeomorphic registration
Fu J; Tzortzakakis A; Barroso J; Westman E; Ferreira D; Moreno R
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2023;15(1):37
Associations between different tau-PET patterns and longitudinal atrophy in the Alzheimer's disease continuum: biological and methodological perspectives from disease heterogeneity
Mohanty R; Ferreira D; Nordberg A; Westman E
Article: NEUROLOGY. 2023;100(8):e846-e859
Cross-sectional Associations of beta-Amyloid, Tau, and Cerebrovascular Biomarkers With Neurodegeneration in Probable Dementia With Lewy Bodies
Ferreira D; Przybelski SA; Lesnick TG; Schwarz CG; Diaz-Galvan P; Graff-Radford J; Senjem ML; Fields JA; Knopman DS; Jones DT; Savica R; Ferman TJ; Graff-Radford N; Lowe VJ; Jack CR; Petersen RC; Westman E; Boeve BF; Kantarci K
Article: NPJ PARKINSON'S DISEASE. 2023;9(1):5
MRI data-driven clustering reveals different subtypes of Dementia with Lewy bodies
Inguanzo A; Poulakis K; Mohanty R; Schwarz CG; Przybelski SA; Diaz-Galvan P; Lowe VJ; Boeve BF; Lemstra AW; van de Beek M; van der Flier W; Barkhof F; Blanc F; de Sousa PL; Philippi N; Cretin B; Demuynck C; Nedelska Z; Hort J; Segura B; Junque C; Oppedal K; Aarsland D; Westman E; Kantarci K; Ferreira D
Article: FRONTIERS IN AGING NEUROSCIENCE. 2023;15:1303036
A deep learning model for brain age prediction using minimally preprocessed T1w images as input
Dartora C; Marseglia A; Martensson G; Rukh G; Dang J; Muehlboeck J-S; Wahlund L-O; Moreno R; Barroso J; Ferreira D; Schioth HB; Westman E
Article: NEUROLOGY. 2022;99(15):e1619-e1629
Association of Cerebrovascular and Alzheimer Disease Biomarkers With Cholinergic White Matter Degeneration in Cognitively Unimpaired Individuals
Cedres N; Ferreira D; Nemy M; Machado A; Pereira JB; Shams S; Wahlund L-O; Zettergren A; Stepankova O; Vyslouzilova L; Eriksdotter M; Teipel S; Grothe MJ; Blennow K; Zetterberg H; Scholl M; Kern S; Skoog I; Westman E
Article: MULTIPLE SCLEROSIS JOURNAL - EXPERIMENTAL, TRANSLATIONAL AND CLINICAL. 2022;8(4):20552173221144230
Association between brain volume and disability over time in multiple sclerosis
Moridi T; Stawiarz L; McKay KA; Ineichen BV; Ouellette R; Ferreira D; Muehlboeck J-S; Westman E; Kockum I; Olsson T; Piehl F; Hillert J; Manouchehrinia A; Granberg T
Article: PARKINSONISM AND RELATED DISORDERS. 2022;102:19-29
Unraveling Parkinson's disease heterogeneity using subtypes based on multimodal data
Albrecht F; Poulakis K; Freidle M; Johansson H; Ekman U; Volpe G; Westman E; Pereira JB; Franz E
Article: NATURE COMMUNICATIONS. 2022;13(1):4566
Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer's disease
Poulakis K; Pereira JB; Muehlboeck J-S; Wahlund L-O; Smedby O; Volpe G; Masters CL; Ames D; Niimi Y; Iwatsubo T; Ferreira D; Westman E
Article: NEUROLOGY. 2022;99(4):e323-e333
Neuropathologic Features of Antemortem Atrophy-Based Subtypes of Alzheimer Disease
Mohanty R; Ferreira D; Frerich S; Muehlboeck J-S; Grothe MJ; Westman E
Article: ALZHEIMER'S AND DEMENTIA. 2022;18(7):1383-1395
The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals
Salvado G; Ferreira D; Operto G; Cumplido-Mayoral I; Arenaza-Urquijo EM; Cacciaglia R; Falcon C; Vilor-Tejedor N; Minguillon C; Groot C; van der Flier WM; Barkhof F; Scheltens P; Ossenkoppele R; Kern S; Zettergren A; Skoog I; Hort J; Stomrud E; van Westen D; Hansson O; Molinuevo JL; Wahlund L-O; Westman E; Gispert JD
Article: NATURE. 2022;604(7906):525-533
Brain charts for the human lifespan
Bethlehem RAI; Seidlitz J; White SR; Vogel JW; Anderson KM; Adamson C; Adler S; Alexopoulos GS; Anagnostou E; Areces-Gonzalez A; Astle DE; Auyeung B; Ayub M; Bae J; Ball G; Baron-Cohen S; Beare R; Bedford SA; Benegal V; Beyer F; Blangero J; Blesa Cabez M; Boardman JP; Borzage M; Bosch-Bayard JF; Bourke N; Calhoun VD; Chakravarty MM; Chen C; Chertavian C; Chetelat G; Chong YS; Cole JH; Corvin A; Costantino M; Courchesne E; Crivello F; Cropley VL; Crosbie J; Crossley N; Delarue M; Delorme R; Desrivieres S; Devenyi GA; Di Biase MA; Dolan R; Donald KA; Donohoe G; Dunlop K; Edwards AD; Elison JT; Ellis CT; Elman JA; Eyler L; Fair DA; Feczko E; Fletcher PC; Fonagy P; Franz CE; Galan-Garcia L; Gholipour A; Giedd J; Gilmore JH; Glahn DC; Goodyer IM; Grant PE; Groenewold NA; Gunning FM; Gur RE; Gur RC; Hammill CF; Hansson O; Hedden T; Heinz A; Henson RN; Heuer K; Hoare J; Holla B; Holmes AJ; Holt R; Huang H; Im K; Ipser J; Jack CRJ; Jackowski AP; Jia T; Johnson KA; Jones PB; Jones DT; Kahn RS; Karlsson H; Karlsson L; Kawashima R; Kelley EA; Kern S; Kim KW; Kitzbichler MG; Kremen WS; Lalonde F; Landeau B; Lee S; Lerch J; Lewis JD; Li J; Liao W; Liston C; Lombardo MV; Lv J; Lynch C; Mallard TT; Marcelis M; Markello RD; Mathias SR; Mazoyer B; McGuire P; Meaney MJ; Mechelli A; Medic N; Misic B; Morgan SE; Mothersill D; Nigg J; Ong MQW; Ortinau C; Ossenkoppele R; Ouyang M; Palaniyappan L; Paly L; Pan PM; Pantelis C; Park MM; Paus T; Pausova Z; Paz-Linares D; Pichet Binette A; Pierce K; Qian X; Qiu J; Qiu A; Raznahan A; Rittman T; Rodrigue A; Rollins CK; Romero-Garcia R; Ronan L; Rosenberg MD; Rowitch DH; Salum GA; Satterthwaite TD; Schaare HL; Schachar RJ; Schultz AP; Schumann G; Scholl M; Sharp D; Shinohara RT; Skoog I; Smyser CD; Sperling RA; Stein DJ; Stolicyn A; Suckling J; Sullivan G; Taki Y; Thyreau B; Toro R; Traut N; Tsvetanov KA; Turk-Browne NB; Tuulari JJ; Tzourio C; Vachon-Presseau E; Valdes-Sosa MJ; Valdes-Sosa PA; Valk SL; van Amelsvoort T; Vandekar SN; Vasung L; Victoria LW; Villeneuve S; Villringer A; Vertes PE; Wagstyl K; Wang YS; Warfield SK; Warrier V; Westman E; Westwater ML; Whalley HC; Witte AV; Yang N; Yeo B; Yun H; Zalesky A; Zar HJ; Zettergren A; Zhou JH; Ziauddeen H; Zugman A; Zuo XN; Bullmore ET; Alexander-Bloch AF
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2022;14(1):14
Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data
Abdelnour C; Ferreira D; van de Beek M; Cedres N; Oppedal K; Cavallin L; Blanc F; Bousiges O; Wahlund L-O; Pilotto A; Padovani A; Boada M; Pagonabarraga J; Kulisevsky J; Aarsland D; Lemstra AW; Westman E
Article: NEUROBIOLOGY OF AGING. 2022;109:204-215
MRI-derived brain age as a biomarker of ageing in rats: validation using a healthy lifestyle intervention
Brusini I; MacNicol E; Kim E; Smedby O; Wang C; Westman E; Veronese M; Turkheimer F; Cash D
Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2022;14(1):e12295
Plasma and CSF NfL are differentially associated with biomarker evidence of neurodegeneration in a community-based sample of 70-year-olds
Dittrich A; Ashton NJ; Zetterberg H; Blennow K; Simren J; Geiger F; Zettergren A; Shams S; Machado A; Westman E; Scholl M; Skoog I; Kern S
Article: ALZHEIMER'S AND DEMENTIA. 2022;18(1):29-42
Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe
Boccardi M; Monsch AU; Ferrari C; Altomare D; Berres M; Bos I; Buchmann A; Cerami C; Didic M; Festari C; Nicolosi V; Sacco L; Aerts L; Albanese E; Annoni J-M; Ballhausen N; Chicherio C; Demonet J-F; Descloux V; Diener S; Ferreira D; Georges J; Gietl A; Girtler N; Kilimann I; Kloppel S; Kustyniuk N; Mecocci P; Mella N; Pigliautile M; Seeher K; Shirk SD; Toraldo A; Brioschi-Guevara A; Chan KCG; Crane PK; Dodich A; Grazia A; Kochan NA; de Oliveira FF; Nobili F; Kukull W; Peters O; Ramakers I; Sachdev PS; Teipel S; Visser PJ; Wagner M; Weintraub S; Westman E; Froelich L; Brodaty H; Dubois B; Cappa SF; Salmon D; Winblad B; Frisoni GB; Kliegel M
Article: FRONTIERS IN AGING NEUROSCIENCE. 2022;14:897674
MRI Markers of Small Vessel Disease and the APOE Allele in Cognitive Impairment
Shams M; Shams S; Martola J; Cavallin L; Granberg T; Kaijser M; Wintermark M; Westman E; Aspelin P; Wiberg MK; Wahlund L-O
Article: NEUROIMAGE. 2021;244:118606
Deep learning from MRI-derived labels enables automatic brain tissue classification on human brain CT
Srikrishna M; Pereira JB; Heckemann RA; Volpe G; van Westen D; Zettergren A; Kern S; Wahlund L-O; Westman E; Skoog I; Scholl M
Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2021;76(12):2275-2283
Metabolic Syndrome Is Associated With Poor Cognition: A Population-Based Study of 70-Year-Old Adults Without Dementia
Marseglia A; Darin-Mattsson A; Skoog J; Ryden L; Hadarsson-Bodin T; Kern S; Sterner TR; Shang Y; Zettergren A; Westman E; Skoog I
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2021;84(1):103-117
Assessment of Tau Pathology as Measured by ¹⁸F-THK5317 and ¹⁸F-Flortaucipir PET and Their Relation to Brain Atrophy and Cognition in Alzheimer's Disease
Colato E; Chiotis K; Ferreira D; Mazrina MS; Lemoine L; Mohanty R; Westman E; Nordberg A; Rodriguez-Vieitez E
Article: NEUROLOGY. 2021;97(16):e1608-e1619
Atrial Fibrillation, Stroke, and Silent Cerebrovascular Disease A Population-based MRI Study
Ryden L; Sacuiu S; Wetterberg H; Najar J; Guo X; Kern S; Zettergren A; Shams S; Pereira JB; Wahlund L-O; Westman E; Skoog I
Article: JOURNAL OF PARKINSON’S DISEASE. 2021;11(4):2057-2071
Effects of a Highly Challenging Balance Training Program on Motor Function and Brain Structure in Parkinson's Disease
Albrecht F; Pereira JB; Mijalkov M; Freidle M; Johansson H; Ekman U; Westman E; Franzen E
Article: NEUROSCIENCE. 2021;472:1-10
Seeing Beyond Your Nose? The Effects of Lifelong Olfactory Sensory Deprivation on Cerebral Audio-visual Integration
Peter MG; Martensson G; Postma EM; Nordin LE; Westman E; Boesveldt S; Lundstrom JN
Article: NEUROBIOLOGY OF AGING. 2021;105:252-261
Cerebrovascular disease, neurodegeneration, and clinical phenotype in dementia with Lewy bodies
Ferreira D; Nedelska Z; Graff-Radford J; Przybelski SA; Lesnick TG; Schwarz CG; Botha H; Senjem ML; Fields JA; Knopman DS; Savica R; Ferman TJ; Graff-Radford NR; Lowe VJ; Jack CR; Petersen RC; Lemstra AW; van de Beek M; Barkhof F; Blanc F; de Sousa PL; Philippi N; Cretin B; Demuynck C; Hort J; Oppedal K; Boeve BF; Aarsland D; Westman E; Kantarci K
Article: AGING. 2021;13(16):19963-19977
The interplay between gray matter and white matter neurodegeneration in subjective cognitive decline
Cedres N; Diaz-Galvan P; Diaz-Flores L; Muehlboeck J-S; Molina Y; Barroso J; Westman E; Ferreira D
Article: CEREBRAL CORTEX. 2021;31(8):3832-3845
Cortical Networks Underpinning Compensation of Verbal Fluency in Normal Aging
Gonzalez-Burgos L; Pereira JB; Mohanty R; Barroso J; Westman E; Ferreira D
Article: ALZHEIMER'S AND DEMENTIA. 2021;17(7):1145-1156
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease
Simren J; Leuzy A; Karikari TK; Hye A; Benedet AL; Lantero-Rodriguez J; Mattsson-Carlgren N; Scholl M; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Aarsland D; Hansson O; Rosa-Neto P; Westman E; Blennow K; Zetterberg H; Ashton NJ
Article: BMC ORAL HEALTH. 2021;21(1):297
Cognitive changes and neural correlates after oral rehabilitation procedures in older adults: a protocol for an interventional study
Hedberg L; Ekman U; Nordin LE; Smedberg J-I; Skott P; Seiger A; Sandborgh-Englund G; Westman E; Kumar A; Trulsson M
Article: AGING. 2021;13(10):13430-13442
Cognitive dedifferentiation as a function of cognitive impairment in the ADNI and MemClin cohorts
Wallert J; Rennie A; Ferreira D; Muehlboeck J-S; Wahlund L-O; Westman E; Ekman U
Article: NEUROBIOLOGY OF AGING. 2021;101:1-12
Effects of amyloid pathology and the APOE ε4 allele on the association between cerebrospinal fluid Aβ38 and Aβ40 and brain morphology in cognitively normal 70-years-olds
Lindberg O; Kern S; Skoog J; Machado A; Pereira JB; Sacuiu SF; Wahlund L-O; Blennow K; Zetterberg H; Zettergren A; Westman E; Skoog I
Article: SCIENTIFIC REPORTS. 2021;11(1):4356
Comparing different approaches for operationalizing subjective cognitive decline: impact on syndromic and biomarker profiles
Diaz-Galvan P; Ferreira D; Cedres N; Falahati F; Andres Hernandez-Cabrera J; Ames D; Barroso J; Westman E
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2021;13(1):49
Data-driven FDG-PET subtypes of Alzheimer's disease-related neurodegeneration
Levin F; Ferreira D; Lange C; Dyrba M; Westman E; Buchert R; Teipel SJ; Grothe MJ
Article: BRAIN COMMUNICATIONS. 2021;3(1):fcaa238
Longitudinal deterioration of white-matter integrity: heterogeneity in the ageing population
Poulakis K; Reid RI; Przybelski SA; Knopman DS; Graff-Radford J; Lowe VJ; Mielke MM; Machulda MM; Jack CRJ; Petersen RC; Westman E; Vemuri P
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2021;79(1):423-431
ANMerge: A Comprehensive and Accessible Alzheimer's Disease Patient-Level Dataset
Birkenbihl C; Westwood S; Shi L; Nevado-Holgado A; Westman E; Lovestone S; Hofmann-Apitius M
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2021;50(5):491-497
Demographic and Clinical Characteristics of Individuals with Mild Cognitive Impairment Related to Grade of Alcohol Consumption
Tsevis T; Westman E; Poulakis K; Lindberg O; Badji A; Religa D; Wahlund L-O
Article: FRONTIERS IN AGING NEUROSCIENCE. 2021;13:777475
Cerebrospinal Fluid Biomarkers, Brain Structural and Cognitive Performances Between Normotensive and Hypertensive Controlled, Uncontrolled and Untreated 70-Year-Old Adults
Badji A; Pereira JB; Shams S; Skoog J; Marseglia A; Poulakis K; Ryden L; Blennow K; Zetterberg H; Kern S; Zettergren A; Wahlund L-O; Girouard H; Skoog I; Westman E
Article: FRONTIERS IN COMPUTATIONAL NEUROSCIENCE. 2021;15:785244
Comparison of Two-Dimensional- and Three-Dimensional-Based U-Net Architectures for Brain Tissue Classification in One-Dimensional Brain CT
Srikrishna M; Heckemann RA; Pereira JB; Volpe G; Zettergren A; Kern S; Westman E; Skoog I; Scholl M
Article: FRONTIERS IN AGING NEUROSCIENCE. 2021;13:656990
Cerebrovascular Disease and Depressive Symptomatology in Individuals With Subjective Cognitive Decline: A Community-Based Study
Diaz-Galvan P; Cedres N; Figueroa N; Barroso J; Westman E; Ferreira D
Article: FRONTIERS IN AGING NEUROSCIENCE. 2021;13:644611
Functional Connectivity and Compensation of Phonemic Fluency in Aging
Mohanty R; Gonzalez-Burgos L; Diaz-Flores L; Muehlboeck J-S; Barroso J; Ferreira D; Westman E
Article: FRONTIERS IN AGING NEUROSCIENCE. 2021;13:694254
The Cognitive Connectome in Healthy Aging
Garcia-Cabello E; Gonzalez-Burgos L; Pereira JB; Andres Hernandez-Cabrera J; Westman E; Volpe G; Barroso J; Ferreira D
Article: FRONTIERS IN BIG DATA. 2021;4:661110
Inter-Cohort Validation of SuStaIn Model for Alzheimer's Disease
Archetti D; Young AL; Oxtoby NP; Ferreira D; Martensson G; Westman E; Alexander DC; Frisoni GB; Redolfi A
Article: CEREBRAL CORTEX. 2021;31(1):159-168
Normal Olfactory Functional Connectivity Despite Lifelong Absence of Olfactory Experiences
Peter MG; Fransson P; Martensson G; Postma EM; Nordin LE; Westman E; Boesveldt S; Lundstrom JN
Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2021;13(1):e12141
Sex differences in CSF biomarkers for neurodegeneration and blood-brain barrier integrity
Skillback T; Blennow K; Zetterberg H; Shams S; Machado A; Pereira J; Lindberg O; Mielke MM; Zettergren A; Ryden L; Westman E; Wahlund L-O; Skoog I; Kern S
Article: PSYCHIATRY RESEARCH - NEUROIMAGING. 2020;306:111184
Cerebrovascular pathology in Alzheimer's disease: Hopes and gaps
Badji A; Westman E
Article: NEUROLOGY. 2020;95(24):e3257-e3268
β-Amyloid and tau biomarkers and clinical phenotype in dementia with Lewy bodies
Ferreira D; Przybelski SA; Lesnick TG; Lemstra AW; Londos E; Blanc F; Nedelska Z; Schwarz CG; Graff-Radford J; Senjem ML; Fields JA; Knopman DS; Savica R; Ferman TJ; Graff-Radford NR; Lowe VJ; Jack CR; Petersen RC; Mollenhauer B; Garcia-Ptacek S; Abdelnour C; Hort J; Bonanni L; Oppedal K; Kramberger MG; Boeve BF; Aarsland D; Westman E; Kantarci K
Article: MEDICAL IMAGE ANALYSIS. 2020;66:101714
The reliability of a deep learning model in clinical out-of-distribution MRI data: A multicohort study
Martensson G; Ferreira D; Granberg T; Cavallin L; Oppedal K; Padovani A; Rektorova I; Bonanni L; Pardini M; Kramberger MG; Taylor J-P; Hort J; Snaedal J; Kulisevsky J; Blanc F; Antonini A; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Simmons A; Aarsland D; Westman E
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2020;78(3):1229-1236
Cerebrospinal Fluid Metals and the Association with Cerebral Small Vessel Disease
Shams M; Martola J; Charidimou A; Granberg T; Ferreira D; Westman E; Wintermark M; Iv M; Larvie M; Wiberg MK; Kaijser M; Forsgard N; Zetterberg H; Wahlund L-O; Shams S
Article: PARKINSONISM AND RELATED DISORDERS. 2020;79:18-25
Automated brainstem volumetry can aid in the diagnostics of parkinsonian disorders
Sjostrom H; Granberg T; Hashim F; Westman E; Svenningsson P
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2020;47(10):2407-2416
High-resolution PET imaging reveals subtle impairment of the serotonin transporter in an early non-depressed Parkinson's disease cohort
Fazio P; Ferreira D; Svenningsson P; Halldin C; Farde L; Westman E; Varrone A
Article: NEUROIMAGE. 2020;218:117005
Morphological changes in secondary, but not primary, sensory cortex in individuals with life-long olfactory sensory deprivation
Peter MG; Martensson G; Postma EM; Nordin LE; Westman E; Boesveldt S; Lundstrom JN
Article: NATURE COMMUNICATIONS. 2020;11(1):4016
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Elvsashagen T; Bahrami S; van der Meer D; Agartz I; Alnaes D; Barch DM; Baur-Streubel R; Bertolino A; Beyer MK; Blasi G; Borgwardt S; Boye B; Buitelaar J; Boen E; Celius EG; Cervenka S; Conzelmann A; Coynel D; Di Carlo P; Djurovic S; Eisenacher S; Espeseth T; Fatouros-Bergman H; Flyckt L; Franke B; Frei O; Gelao B; Harbo HF; Hartman CA; Haberg A; Heslenfeld D; Hoekstra PJ; Hogestol EA; Jonassen R; Jonsson EG; Kirsch P; Kloszewska I; Lagerberg TV; Landro NI; Le Hellard S; Lesch K-P; Maglanoc LA; Malt UF; Mecocci P; Melle I; Meyer-Lindenberg A; Moberget T; Nordvik JE; Nyberg L; O'Connell KS; Oosterlaan J; Papalino M; Papassotiropoulos A; Pauli P; Pergola G; Persson K; de Quervain D; Reif A; Rokicki J; van Rooij D; Shadrin AA; Schmidt A; Schwarz E; Selbaek G; Soininen H; Sowa P; Steen VM; Tsolaki M; Vellas B; Wang L; Westman E; Ziegler GC; Zink M; Andreassen OA; Westlye LT; Kaufmann T; Farde L; Flyckt L; Engberg G; Erhardt SS; Fatouros-Bergman H; Cervenka S; Schwieler L; Piehl F; Agartz I; Collste K; Victorsson P; Malmqvist A; Hedberg M; Orhan F; Sellgren CM
Article: AGING. 2020;12(13):12622-12647
Fully bayesian longitudinal unsupervised learning for the assessment and visualization of AD heterogeneity and progression
Poulakis K; Ferreira D; Pereira JB; Smedby O; Vemuri P; Westman E
Article: BRAIN AND BEHAVIOR. 2020;10(7):e01662
Visual rating versus volumetry of regional brain atrophy and longitudinal changes over a 5-year period in an elderly population
Velickaite V; Ferreira D; Lind L; Ahlstrom H; Kilander L; Westman E; Larsson E-M
Article: NEUROBIOLOGY OF DISEASE. 2020;139:104831
Longitudinal degeneration of the basal forebrain predicts subsequent dementia in Parkinson's disease
Pereira JB; Hall S; Jalakas M; Grothe MJ; Strandberg O; Stomrud E; Westman E; van Westen D; Hansson O
Article: NEUROLOGY. 2020;94(19):e2026-e2036
Cortical microstructural correlates of astrocytosis in autosomal-dominant Alzheimer disease
Vilaplana E; Rodriguez-Vieitez E; Ferreira D; Montal V; Almkvist O; Wall A; Lleo A; Westman E; Graff C; Fortea J; Nordberg A
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2020;12(1):51
The cholinergic system in subtypes of Alzheimer's disease: an in vivo longitudinal MRI study
Machado A; Ferreira D; Grothe MJ; Eyjolfsdottir H; Almqvist PM; Cavallin L; Lind G; Linderoth B; Seiger A; Teipel S; Wahlberg LU; Wahlund L-O; Westman E; Eriksdotter M
Article: NEUROIMAGE. 2020;211:116607
Cholinergic white matter pathways make a stronger contribution to attention and memory in normal aging than cerebrovascular health and nucleus basalis of Meynert
Nemy M; Cedres N; Grothe MJ; Muehlboeck J-S; Lindberg O; Nedelska Z; Stepankova O; Vyslouzilova L; Eriksdotter M; Barroso J; Teipel S; Westman E; Ferreira D
Article: HUMAN BRAIN MAPPING. 2020;41(6):1557-1572
The heterogeneous functional architecture of the posteromedial cortex is associated with selective functional connectivity differences in Alzheimer's disease
Khan W; Amad A; Giampietro V; Werden E; De Simoni S; O'Muircheartaigh J; Westman E; O'Daly O; Williams SCR; Brodtmann A
Article: NEUROBIOLOGY OF AGING. 2020;88:61-70
Cerebrospinal fluid progranulin is associated with increased cortical thickness in early stages of Alzheimer's disease
Batzu L; Westman E; Pereira JB
Article: BMC GERIATRICS. 2020;20(1):93
The MemClin project: a prospective multi memory clinics study targeting early stages of cognitive impairment
Ekman U; Ferreira D; Muehlboeck J-S; Wallert J; Rennie A; Eriksdotter M; Wahlund L-O; Westman E
Article: ALZHEIMER'S AND DEMENTIA. 2020;16(2):335-344
Distinct tau PET patterns in atrophy-defined subtypes of Alzheimer's disease
Ossenkoppele R; Lyoo CH; Sudre CH; van Westen D; Cho H; Ryu YH; Choi JY; Smith R; Strandberg O; Palmqvist S; Westman E; Tsai R; Kramer J; Boxer AL; Gorno-Tempini ML; La Joie R; Miller BL; Rabinovici GD; Hansson O
Article: AGING. 2020;12(1):894-901
Predicting Fazekas scores from automatic segmentations of white matter signal abnormalities
Cedres N; Ferreira D; Machado A; Shams S; Sacuiu S; Waern M; Wahlund L-O; Zettergren A; Kern S; Skoog I; Westman E
Article: NEURODEGENERATIVE DISEASES. 2020;20(4):153-164
Brain Atrophy Subtypes and the ATN Classification Scheme in Alzheimer's Disease
Cedres N; Ekman U; Poulakis K; Shams S; Cavallin L; Muehlboeck S; Granberg T; Wahlund L-O; Ferreira D; Westman E
Article: FRONTIERS IN PSYCHOLOGY. 2020;11:600841
Evaluation of a Novel Psychological Intervention Tailored for Patients With Early Cognitive Impairment (PIPCI): Study Protocol of a Randomized Controlled Trial
Ekman U; Kemani MK; Wallert J; Wicksell RK; Holmstrom L; Ngandu T; Rennie A; Akenine U; Westman E; Kivipelto M
Article: BRAIN COMMUNICATIONS. 2020;2(2):fcaa192
Comparison of subtyping methods for neuroimaging studies in Alzheimer's disease: a call for harmonization
Mohanty R; Martensson G; Poulakis K; Muehlboeck J-S; Rodriguez-Vieitez E; Chiotis K; Grothe MJ; Nordberg A; Ferreira D; Westman E
Article: NEUROBIOLOGY OF AGING. 2020;85:74-82
Apathy and anxiety are early markers of Alzheimer's disease
Johansson M; Stomrud E; Lindberg O; Westman E; Johansson PM; van Westen D; Mattsson N; Hansson O
Article: FRONTIERS IN NEUROSCIENCE. 2020;14:15
Shape Information Improves the Cross-Cohort Performance of Deep Learning-Based Segmentation of the Hippocampus
Brusini I; Lindberg O; Muehlboeck J-S; Smedby O; Westman E; Wang C
Article: NEUROIMAGE: CLINICAL. 2020;27:102333
The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies
Abdelnour C; Ferreira D; Oppedal K; Cavallin L; Bousiges O; Wahlund LO; Hort J; Nedelska Z; Padovani A; Pilotto A; Bonanni L; Kramberger MG; Boada M; Westman E; Pagonabarraga J; Kulisevsky J; Blanc F; Aarsland D
Article: NEUROIMAGE: CLINICAL. 2020;27:102310
Medial temporal atrophy in preclinical dementia: Visual and automated assessment during six year follow-up
Martensson G; Hakansson C; Pereira JB; Palmqvist S; Hansson O; van Westen D; Westman E
Article: ELIFE. 2019;8:e50830
Amyloid and tau accumulate across distinct spatial networks and are differentially associated with brain connectivity
Pereira JB; Ossenkoppele R; Palmqvist S; Strandberg TO; Smith R; Westman E; Hansson O
Article: NATURE GENETICS. 2019;51(11):1624-1636
Genetic architecture of subcortical brain structures in 38,851 individuals
Satizabal CL; Adams HHH; Hibar DP; White CC; Knol MJ; Stein JL; Scholz M; Sargurupremraj M; Jahanshad N; Roshchupkin GV; Smith AV; Bis JC; Jian X; Luciano M; Hofer E; Teumer A; van der Lee SJ; Yang J; Yanek LR; Lee TV; Li S; Hu Y; Koh JY; Eicher JD; Desrivieres S; Arias-Vasquez A; Chauhan G; Athanasiu L; Rentera ME; Kim S; Hoehn D; Armstrong NJ; Chen Q; Holmes AJ; den Braber A; Kloszewska I; Andersson M; Espeseth T; Grimm O; Abramovic L; Alhusaini S; Milaneschi Y; Papmeyer M; Axelsson T; Ehrlich S; Roiz-Santianez R; Kraemer B; Haberg AK; Jones HJ; Pike GB; Stein DJ; Stevens A; Bralten J; Vernooij MW; Harris TB; Filippi I; Witte AV; Guadalupe T; Wittfeld K; Mosley TH; Becker JT; Nhat TD; Hagenaars SP; Saba Y; Cuellar-Partida G; Amin N; Hilal S; Nho K; Mirza-Schreiber N; Arfanakis K; Becker DM; Ames D; Goldman AL; Lee PH; Boomsma DI; Lovestone S; Giddaluru S; Le Hellard S; Mattheisen M; Bohlken MM; Kasperaviciute D; Schmaal L; Lawrie SM; Agartz I; Walton E; Tordesillas-Gutierrez D; Davies GE; Shin J; Ipser JC; Vinke LN; Hoogman M; Jia T; Burkhardt R; Klein M; Crivello F; Janowitz D; Carmichael O; Haukvik UK; Aribisala BS; Schmidt H; Strike LT; Cheng C-Y; Risacher SL; Puetz B; Fleischman DA; Assareh AA; Mattay VS; Buckner RL; Mecocci P; Dale AM; Cichon S; Boks MP; Matarin M; Penninx BWJH; Calhoun VD; Chakravarty MM; Marquand AF; Macare C; Masouleh SK; Oosterlaan J; Amouyel P; Hegenscheid K; Rotter JI; Schork AJ; Liewald DCM; de ZGI; Wong TY; Shen L; Saemann PG; Brodaty H; Roffman JL; de Geus EJC; Tsolaki M; Erk S; van Eijk KR; Cavalleri GL; van der Wee NJA; McIntosh AM; Gollub RL; Bulayeva KB; Bernard M; Richards JS; Himali JJ; Loeffler M; Rommelse N; Hoffmann W; Westlye LT; Hernandez MCV; Hansell NK; van Erp TGM; Wolf C; Kwok JBJ; Vellas B; Heinz A; Loohuis LMO; Delanty N; Ho B-C; Ching CRK; Shumskaya E; Singh B; Hofman A; van der Meer D; Homuth G; Psaty BM; Bastin ME; Montgomery GW; Foroud TM; Reppermund S; Hottenga J-J; Simmons A; Meyer-Lindenberg A; Cahn W; Whelan CD; van Donkelaar MMJ; Yang Q; Hosten N; Green RC; Thalamuthu A; Mohnke S; Pol HEH; Lin H; Jack CRJ; Schofield PR; Muehleisen TW; Maillard P; Potkin SG; Wen W; Fletcher E; Toga AW; Gruber O; Huentelman M; Smith GD; Launer LJ; Nyberg L; Jonsson EG; Crespo-Facorro B; Koen N; Greve DN; Uitterlinden AG; Weinberger DR; Steen VM; Fedko IO; Groenewold NA; Niessen WJ; Toro R; Tzourio C; Longstreth WTJ; Ikram MK; Smoller JW; van Tol M-J; Sussmann JE; Paus T; Lemaitre H; Schroeter ML; Mazoyer B; Andreassen OA; Holsboer F; Depondt C; Veltman DJ; Turner JA; Pausova Z; Schumann G; van Rooij D; Djurovic S; Deary IJ; McMahon KL; Mueller-Myhsok B; Brouwer RM; Soininen H; Pandolfo M; Wassink TH; Cheung JW; Wolfers T; Martinot J-L; Zwiers MP; Nauck M; Melle I; Martin NG; Kanai R; Westman E; Kahn RS; Sisodiya SM; White T; Saremi A; van Bokhoven H; Brunner HG; Voelzke H; Wright MJ; van't Ent D; Noethen MM; Ophoff RA; Buitelaar JK; Fernandez G; Sachdev PS; Rietschel M; van Haren NEM; Fisher SE; Beiser AS; Francks C; Saykin AJ; Mather KA; Romanczuk-Seiferth N; Hartman CA; DeStefano AL; Heslenfeld DJ; Weiner MW; Walter H; Hoekstra PJ; Nyquist PA; Franke B; Bennett DA; Grabe HJ; Johnson AD; Chen C; van Duijn CM; Lopez OL; Fornage M; Wardlaw JM; Schmidt R; DeCarli C; De Jager PL; Villringer A; Debette S; Gudnason V; Medland SE; Shulman JM; Thompson PM; Seshadri S; Ikram MA
Article: NATURE NEUROSCIENCE. 2019;22(10):1617-1623
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Kaufmann T; van der Meer D; Nhat TD; Schwarz E; Lund MJ; Agartz I; Alnaes D; Barch DM; Baur-Streubel R; Bertolino A; Bettella F; Beyer MK; Boen E; Borgwardt S; Brandt CL; Buitelaar J; Celius EG; Cervenka S; Conzelmann A; Cordova-Palomera A; Dale AM; de Quervain DJF; Carlo P; Djurovic S; Dorum ES; Eisenacher S; Elvsashagen T; Espeseth T; Fatouros-Bergman H; Flyckt L; Franke B; Frei O; Haatveit B; Haberg AK; Harbo HF; Hartman CA; Heslenfeld D; Hoekstra PJ; Hogestol EA; Jernigan TL; Jonassen R; Jonsson EG; Kirsch P; Ktoszewska I; Kolskar KK; Landro NI; Hellard S; Lesch K-P; Lovestone S; Lundervold A; Lundervold AJ; Maglanoc LA; Malt UF; Mecocci P; Melle I; Meyer-Lindenberg A; Moberget T; Norbom LB; Nordvik JE; Nyberg L; Oosterlaan J; Papalino M; Papassotiropoulos A; Pauli P; Pergola G; Persson K; Richard G; Rokicki J; Sanders A-M; Selbaek G; Shadrin AA; Smeland OB; Soininen H; Sowa P; Steen VM; Tsolaki M; Ulrichsen KM; Vellas B; Wang L; Westman E; Ziegler GC; Zink M; Andreassen OA; Westlye LT; Farde L; Flyckts L; Engberg G; Erhardt S; Fatouros-Bergmann H; Schwieler L; Piehl F; Collste K; Victorsson P; Malmqvist A; Hedberg M; Orhan F
Article: PSYCHIATRY RESEARCH - NEUROIMAGING. 2019;289:37-44
Cortical structure abnormalities in females with conduct disorder prior to age 15
Budhiraja M; Pereira JB; Lindner P; Westman E; Jokinen J; Savic I; Tiihonen J; Hodgins S
Article: AGING. 2019;11(12):4090-4106
Cognitive compensatory mechanisms in normal aging: a study on verbal fluency and the contribution of other cognitive functions
Gonzalez-Burgos L; Andres Hernandez-Cabrera J; Westman E; Barroso J; Ferreira D
Article: SCIENTIFIC REPORTS. 2019;9(1):6079
Mapping of apparent susceptibility yields promising diagnostic separation of progressive supranuclear palsy from other causes of parkinsonism
Sjostrom H; Surova Y; Nilsson M; Granberg T; Westman E; van Westen D; Svenningsson P; Hansson O
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2019;68(1):295-309
Subjective Cognitive Decline Below and Above the Age of 60: A Multivariate Study on Neuroimaging, Cognitive, Clinical, and Demographic Measures
Cedres N; Machado A; Molina Y; Diaz-Galvan P; Andres Hernandez-Cabrera J; Barroso J; Westman E; Ferreira D
Article: EUROPEAN RADIOLOGY. 2019;29(3):1355-1364
Repeatability and reproducibility of FreeSurfer, FSL-SIENAX and SPM brain volumetric measurements and the effect of lesion filling in multiple sclerosis
Guo C; Ferreira D; Fink K; Westman E; Granberg T
Article: ALZHEIMER'S AND DEMENTIA. 2019;15(3):400-409
A signature pattern of cortical atrophy in dementia with Lewy bodies: A study on 333 patients from the European DLB consortium
Oppedal K; Ferreira D; Cavallin L; Lemstra AW; ten Kate M; Padovani A; Rektorova I; Bonanni L; Wahlund L-O; Engedal K; Nobili F; Kramberger M; Taylor J-P; Hort JN; Snaedal J; Blanc F; Walker Z; Antonini A; Westman E; Aarsland D
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2019;34(2):191-209
The Gothenburg H70 Birth cohort study 2014-16: design, methods and study population
Sterner TR; Ahlner F; Blennow K; Dahlin-Ivanoff S; Falk H; Johansson LH; Hoff M; Holm M; Horder H; Jacobsson T; Johansson B; Johansson L; Kern J; Kern S; Machado A; Fassberg MM; Nilsson J; Ribbe M; Rothenberg E; Ryden L; Sadeghi A; Sacuiu S; Samuelsson J; Sigstrom R; Skoog J; Thorvaldsson V; Waern M; Westman E; Wetterberg H; Zetterberg H; Zetterberg M; Zettergren A; Ostling S; Skoog I
Article: NEUROLOGY. 2019;92(5):e395-e405
Brain myoinositol as a potential marker of amyloid-related pathology: A longitudinal study
Voevodskaya O; Poulakis K; Sundgren P; van Westen D; Palmqvist S; Wahlund L-O; Stomrud E; Hansson O; Westman E; Blennow K; Zetterberg H
Article: FRONTIERS IN NEUROLOGY. 2019;10:524
Subtypes of Alzheimer's Disease Display Distinct Network Abnormalities Extending Beyond Their Pattern of Brain Atrophy
Ferreira D; Pereira JB; Volpe G; Westman E
Article: NEUROIMAGE: CLINICAL. 2019;23:101872
AVRA: Automatic visual ratings of atrophy from MRI images using recurrent convolutional neural networks
Martensson G; Ferreira D; Cavallin L; Muehlboeck J-S; Wahlund L-O; Wang C; Westman E
Article: NPJ PARKINSON'S DISEASE. 2019;5:7
Cortical thinning in patients with REM sleep behavior disorder is associated with clinical progression
Pereira JB; Weintraub D; Chahine L; Aarsland D; Hansson O; Westman E
Article: NEUROBIOLOGY OF AGING. 2018;71:179-188
Proposal for a hierarchical, multidimensional, and multivariate approach to investigate cognitive aging
Machado A; Barroso J; Molina Y; Nieto A; Diaz-Flores L; Westman E; Ferreira D
Article: CEREBRAL CORTEX. 2018;28(10):3638-3649
Abnormal Structural Brain Connectome in Individuals with Preclinical Alzheimer's Disease
Pereira JB; van Westen D; Stomrud E; Strandberg TO; Volpe G; Westman E; Hansson O
Article: NEUROBIOLOGY OF AGING. 2018;70:18-29
The contribution of small vessel disease to subtypes of Alzheimer's disease: a study on cerebrospinal fluid and imaging biomarkers
Ferreira D; Shams S; Cavallin L; Viitanen M; Martola J; Granberg T; Shams M; Aspelin P; Kristoffersen-Wiberg M; Nordberg A; Wahlund L-O; Westman E
Article: SCIENTIFIC REPORTS. 2018;8(1):11592
Stability of graph theoretical measures in structural brain networks in Alzheimer's disease
Martensson G; Pereira JB; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Simmons A; Volpe G; Westman E
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45(9):1605-1617
Dual tracer tau PET imaging reveals different molecular targets for ¹¹C-THK5351 and ¹¹C-PBB3 in the Alzheimer brain
Chiotis K; Stenkrona P; Almkvist O; Stepanov V; Ferreira D; Arakawa R; Takano A; Westman E; Varrone A; Okamura N; Shimada H; Higuchi M; Halldin C; Nordberg A
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2018;137(6):491-502
Longitudinal relationships among depressive symptoms, cortisol, and brain atrophy in the neocortex and the hippocampus
Lebedeva A; Sundstrom A; Lindgren L; Stomby A; Aarsland D; Westman E; Winblad B; Olsson T; Nyberg L
Article: SCIENTIFIC REPORTS. 2018;8(1):8431
The A/T/N biomarker scheme and patterns of brain atrophy assessed in mild cognitive impairment
Ekman U; Ferreira D; Westman E
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2018;10(1):45
Reduced penetrance of the PSEN1 H163Y autosomal dominant Alzheimer mutation: a 22-year follow-up study
Thordardottir S; Rodriguez-Vieitez E; Almkvist O; Ferreira D; Saint-Aubert L; Kinhult-Stahlbom A; Thonberg H; Scholl M; Westman E; Wall A; Eriksdotte M; Zetterberg H; Blennow K; Nordberg A; Graff C
Article: NEUROBIOLOGY OF AGING. 2018;65:98-108
Heterogeneous patterns of brain atrophy in Alzheimer's disease
Poulakis K; Pereira JB; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Simmons A; Wahlund L-O; Westman E
Article: EUROPEAN RADIOLOGY. 2018;28(4):1739-1747
Medial temporal lobe atrophy ratings in a large 75-year-old population-based cohort: gender-corrected and education-corrected normative data
Velickaite V; Ferreira D; Cavallin L; Lind L; Ahlstrom H; Kilander L; Westman E; Larsson E-M
Article: NEUROBIOLOGY OF AGING. 2018;64:15-24
Altered structural network organization in cognitively normal individuals with amyloid pathology
Voevodskaya O; Pereira JB; Volpe G; Lindberg O; Stomrud E; van Westen D; Westman E; Hansson O
Article: CEREBRAL CORTEX. 2018;28(1):340-349
Amyloid Network Topology Characterizes the Progression of Alzheimer's Disease During the Predementia Stages
Pereira JB; Strandberg TO; Palmqvist S; Volpe G; van Westen D; Westman E; Hansson O
Article: FRONTIERS IN AGING NEUROSCIENCE. 2018;10:144
Differentiating Patients at the Memory Clinic With Simple Reaction Time Variables: A Predictive Modeling Approach Using Support Vector Machines and Bayesian Optimization
Wallert J; Westman E; Ulinder J; Annerstedt M; Terzis B; Ekman U
Article: FRONTIERS IN AGING NEUROSCIENCE. 2018;10:439
Differential Associations of IL-4 With Hippocampal Subfields in Mild Cognitive Impairment and Alzheimer's Disease
Boccardi V; Westman E; Pelini L; Lindberg O; Muehlboeck J-S; Simmons A; Tarducci R; Floridi P; Chiarini P; Soininen H; Kloszewska I; Tsolaki M; Vellas B; Spenger C; Wahlund L-O; Lovestone S; Mecocci P
Article: PLOS ONE. 2018;13(12):e0208383
Phenotypic variability and neuropsychological findings associated with C9orf72 repeat expansions in a Bulgarian dementia cohort
Mehrabian S; Thonberg H; Raycheva M; Lilius L; Stoyanova K; Forsell C; Cavallin L; Nesheva D; Westman E; Toncheva D; Traykov L; Winblad B; Graff C
Article: PARKINSONISM AND RELATED DISORDERS. 2017;44:51-57
Quantitative susceptibility mapping differentiates between parkinsonian disorders
Sjostrom H; Granberg T; Westman E; Svenningsson P
Article: NEUROBIOLOGY OF AGING. 2017;58:14-29
Association between cerebrospinal fluid and plasma neurodegeneration biomarkers with brain atrophy in Alzheimer's disease
Pereira JB; Westman E; Hansson O
Article: EUROPEAN JOURNAL OF RADIOLOGY. 2017;95:28-32
The Evans' Index revisited: New cut-off levels for use in radiological assessment of ventricular enlargement in the elderly
Brix MK; Westman E; Simmons A; Ringstad GA; Eide PK; Wagner-Larsen K; Page CM; Vitelli V; Beyer MK
Article: INTELLIGENCE. 2017;64:9-17
The worst performance rule with elderly in abnormal cognitive decline
Wallert J; Ekman U; Westman E; Madison G
Article: HIPPOCAMPUS. 2017;27(6):653-667
The interactive effect of demographic and clinical factors on hippocampal volume: A multicohort study on 1958 cognitively normal individuals
Ferreira D; Hansson O; Barroso J; Molina Y; Machado A; Andres Hernandez-Cabrera J; Muehlboeck J-S; Stomrud E; Nagga K; Lindberg O; Ames D; Kalpouzos G; Fratiglioni L; Backman L; Graff C; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Ahlstrom H; Lind L; Larsson E-M; Wahlund L-O; Simmons A; Westman E
Article: MAGNETIC RESONANCE MATERIALS IN PHYSICS, BIOLOGY, AND MEDICINE. 2017;30(3):227-237
Reproducible segmentation of white matter hyperintensities using a new statistical definition
Damangir S; Westman E; Simmons A; Vrenken H; Wahlund L-O; Spulber G
Article: SCIENTIFIC REPORTS. 2017;7:46263
Distinct subtypes of Alzheimer's disease based on patterns of brain atrophy: longitudinal trajectories and clinical applications
Ferreira D; Verhagen C; Andres Hernandez-Cabrera J; Cavallin L; Guo C-J; Ekman U; Muehlboeck J-S; Simmons A; Barroso J; Wahlund L-O; Westman E
Article: SCIENTIFIC REPORTS. 2017;7:44368
A 'Disease Severity Index' to identify individuals with Subjective Memory Decline who will progress to mild cognitive impairment or dementia
Ferreira D; Falahati F; Linden C; Buckley RF; Ellis KA; Savage G; Villemagne VL; Rowe CC; Ames D; Simmons A; Westman E
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2017;214(3):699-717
27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation
Ismail M-A; Mateos L; Maioli S; Merino-Serrais P; Ali Z; Lodeiro M; Westman E; Leitersdorf E; Gulyas B; Olof-Wahlund L; Winblad B; Savitcheva I; Bjorkhem I; Cedazo-Minguez A
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2017;56(3):1159-1174
A Multi-Cohort Study of ApoE ε4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease
Khan W; Giampietro V; Banaschewski T; Barker GJ; Bokde ALW; Buechel C; Conrod P; Flor H; Frouin V; Garavan H; Gowland P; Heinz A; Ittermann B; Lemaitre H; Nees F; Paus T; Pausova Z; Rietschel M; Smolka MN; Stroehle A; Gallinat J; Vellas B; Soininen H; Kloszewska I; Tsolaki M; Mecocci P; Spenger C; Villemagne VL; Masters CL; Muehlboeck J-S; Backman L; Fratiglioni L; Kalpouzos G; Wahlund L-O; Schumann G; Lovestone S; Williams SCR; Westman E; Simmons A
Article: NATURE COMMUNICATIONS. 2017;8:13624
Novel genetic loci associated with hippocampal volume
Hibar DP; Adams HHH; Jahanshad N; Chauhan G; Stein JL; Hofer E; Renteria ME; Bis JC; Arias-Vasquez A; Ikram MK; Desrivieres S; Vernooij MW; Abramovic L; Alhusaini S; Amin N; Andersson M; Arfanakis K; Aribisala BS; Armstrong NJ; Athanasiu L; Axelsson T; Beecham AH; Beiser A; Bernard M; Blanton SH; Bohlken MM; Boks MP; Bralten J; Brickman AM; Carmichael O; Chakravarty MM; Chen Q; Ching CRK; Chouraki V; Cuellar-Partida G; Crivello F; Den Braber A; Nhat TD; Ehrlich S; Giddaluru S; Goldman AL; Gottesman RF; Grimm O; Griswold ME; Guadalupe T; Gutman BA; Hass J; Haukvik UK; Hoehn D; Holmes AJ; Hoogman M; Janowitz D; Jia T; Jorgensen KN; Karbalai N; Kasperaviciute D; Kim S; Klein M; Kraemer B; Lee PH; Liewald DCM; Lopez LM; Luciano M; Macare C; Marquand AF; Matarin M; Mather KA; Mattheisen M; McKay DR; Milaneschi Y; Maniega SM; Nho K; Nugent AC; Nyquist P; Loohuis LMO; Oosterlaan J; Papmeyer M; Pirpamer L; Puetz B; Ramasamy A; Richards JS; Risacher SL; Roiz-Santianez R; Rommelse N; Ropele S; Rose EJ; Royle NA; Rundek T; Saemann PG; Saremi A; Satizabal CL; Schmaal L; Schork AJ; Shen L; Shin J; Shumskaya E; Smith AV; Sprooten E; Strike LT; Teumer A; Tordesillas-Gutierrez D; Toro R; Trabzuni D; Trompet S; Vaidya D; Van der Grond J; Van der Lee SJ; Van der Meer D; Van Donkelaar MMJ; Van Eijk KR; Van Erp TGM; Van Rooij D; Walton E; Westlye LT; Whelan CD; Windham BG; Winkler AM; Wittfeld K; Woldehawariat G; Wolf C; Wolfers T; Yanek LR; Yang J; Zijdenbos A; Zwiers MP; Agartz I; Almasy L; Ames D; Amouyel P; Andreassen OA; Arepalli S; Assareh AA; Barral S; Bastin ME; Becker DM; Becker JT; Bennett DA; Blangero J; van Bokhoven H; Boomsma DI; Brodaty H; Brouwer RM; Brunner HG; Buckner RL; Buitelaar JK; Bulayeva KB; Cahn W; Calhoun VD; Cannon DM; Cavalleri GL; Cheng C-Y; Cichon S; Cookson MR; Corvin A; Crespo-Facorro B; Curran JE; Czisch M; Dale AM; Davies GE; De Craen AJM; De Geus EJC; De Jager PL; De Zubicaray GI; Deary IJ; Debette S; DeCarli C; Delanty N; Depondt C; DeStefano A; Dillman A; Djurovic S; Donohoe G; Drevets WC; Duggirala R; Dyer TD; Enzinger C; Erk S; Espeseth T; Fedko IO; Fernandez G; Ferrucci L; Fisher SE; Fleischman DA; Ford I; Fornage M; Foroud TM; Fox PT; Francks C; Fukunaga M; Gibbs JR; Glahn DC; Gollub RL; Goring HHH; Green RC; Gruber O; Gudnason V; Guelfi S; Haberg AK; Hansell NK; Hardy J; Hartman CA; Hashimoto R; Hegenscheid K; Heinz A; Le Hellard S; Hernandez DG; Heslenfeld DJ; Ho B-C; Hoekstra PJ; Hoffmann W; Hofman A; Holsboer F; Homuth G; Hosten N; Hottenga J-J; Huentelman M; Pol HEH; Ikeda M; Jack CRJ; Jenkinson M; Johnson R; Joensson EG; Jukema JW; Kahn RS; Kanai R; Kloszewska I; Knopman DS; Kochunov P; Kwok JB; Lawrie SM; Lemaitre H; Liu X; Longo DL; Lopez OL; Lovestone S; Martinez O; Martinot J-L; Mattay VS; McDonald C; McIntosh AM; McMahon FJ; McMahon KL; Mecocci P; Melle I; Meyer-Lindenberg A; Mohnke S; Montgomery GW; Morris DW; Mosley TH; Muhleisen TW; Mueller-Myhsok B; Nalls MA; Nauck M; Nichols TE; Niessen WJ; Nothen MM; Nyberg L; Ohi K; Olvera RL; Ophoff RA; Pandolfo M; Paus T; Pausova Z; Penninx BWJH; Pike GB; Potkin SG; Psaty BM; Reppermund S; Rietschel M; Roffman JL; Romanczuk-Seiferth N; Rotter JI; Ryten M; Sacco RL; Sachdev PS; Saykin AJ; Schmidt R; Schmidt H; Schofield PR; Sigursson S; Simmons A; Singleton A; Sisodiya SM; Smith C; Smoller JW; Soininen H; Steen VM; Stott DJ; Sussmann JE; Thalamuthu A; Toga AW; Traynor BJ; Troncoso J; Tsolaki M; Tzourio C; Uitterlinden AG; Hernandez MCV; Van der Brug M; van der Lugt A; van der Wee NJA; Van Haren NEM; van't Ent D; Van Tol M-J; Vardarajan BN; Vellas B; Veltman DJ; Voelzke H; Walter H; Wardlaw JM; Wassink TH; Weale ME; Weinberger DR; Weiner MW; Wen W; Westman E; White T; Wong TY; Wright CB; Zielke RH; Zonderman AB; Martin NG; Van Duijn CM; Wright MJ; Longstreth WT; Schumann G; Grabe HJ; Franke B; Launer LJ; Medland SE; Seshadri S; Thompson PM; Ikram MA
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2017;56(1):327-334
The Effects of Gene Mutations on Default Mode Network in Familial Alzheimer's Disease
Li X; Westman E; Thordardottir S; Stahlbom AK; Almkvist O; Blennow K; Wahlund L-O; Graff C
Article: PLOS ONE. 2017;12(8):e0178798
BRAPH: A graph theory software for the analysis of brain connectivity
Mijalkov M; Kakaei E; Pereira JB; Westman E; Volpe G
Article: PLOS ONE. 2017;12(10):e0186595
MRI-assessed atrophy subtypes in Alzheimer's disease and the cognitive reserve hypothesis
Persson K; Eldholm RS; Barca ML; Cavallin L; Ferreira D; Knapskog A-B; Selbaek G; Braekhus A; Saltvedt I; Westman E; Engedal K
Article: FRONTIERS IN AGING NEUROSCIENCE. 2017;9:306
Atrophy of the Posterior Subiculum Is Associated with Memory Impairment, Tau- and Aβ Pathology in Non-demented Individuals
Lindberg O; Martensson G; Stomrud E; Palmqvist S; Wahlund L-O; Westman E; Hansson O
Article: FRONTIERS IN AGING NEUROSCIENCE. 2017;9:13
MRI-Based Classification Models in Prediction of Mild Cognitive Impairment and Dementia in Late-Life Depression
Lebedeva AK; Westman E; Borza T; Beyer MK; Engedal K; Aarsland D; Selbaek G; Haberg AK
Article: FRONTIERS IN AGING NEUROSCIENCE. 2017;9:188
Cognitive Variability during Middle-Age: Possible Association with Neurodegeneration and Cognitive Reserve
Ferreira D; Machado A; Molina Y; Nieto A; Correia R; Westman E; Barroso J
Article: NEUROIMAGE: CLINICAL. 2017;16:418-428
Monitoring disease progression in mild cognitive impairment: Associations between atrophy patterns, cognition, APOE and amyloid
Falahati F; Ferreira D; Muehlboeck J-S; Eriksdotter M; Simmons A; Wahlund L-O; Westman E
Article: NATURE NEUROSCIENCE. 2016;19(12):1569-1582
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Adams HHH; Hibar DP; Chouraki V; Stein JL; Nyquist PA; Renteria ME; Trompet S; Arias-Vasquez A; Seshadri S; Desrivieres S; Beecham AH; Jahanshad N; Wittfeld K; Van der Lee SJ; Abramovic L; Alhusaini S; Amin N; Andersson M; Arfanakis K; Aribisala BS; Armstrong NJ; Athanasiu L; Axelsson T; Beiser A; Bernard M; Bis JC; Blanken LME; Blanton SH; Bohlken MM; Boks MP; Bralten J; Brickman AM; Carmichael O; Chakravarty MM; Chauhan G; Chen Q; Ching CRK; Cuellar-Partida G; Den Braber A; Doan NT; Ehrlich S; Filippi I; Ge T; Giddaluru S; Goldman AL; Gottesman RF; Greven CU; Grimm O; Griswold ME; Guadalupe T; Hass J; Haukvik UK; Hilal S; Hofer E; Hoehn D; Holmes AJ; Hoogman M; Janowitz D; Jia T; Kasperaviciute D; Kim S; Klein M; Kraemer B; Lee PH; Liao J; Liewald DCM; Lopez LM; Luciano M; Macare C; Marquand A; Matarin M; Mather KA; Mattheisen M; Mazoyer B; Mckay DR; McWhirter R; Milaneschi Y; Mirza-Schreiber N; Muetzel RL; Maniega SM; Nho K; Nugent AC; Loohuis LMO; Oosterlaan J; Papmeyer M; Pappa I; Pirpamer L; Pudas S; Puetz B; Rajan KB; Ramasamy A; Richards JS; Risacher SL; Roiz-Santianez R; Rommelse N; Rose EJ; Royle NA; Rundek T; Saemann PG; Satizabal CL; Schmaal L; Schork AJ; Shen L; Shin J; Shumskaya E; Smith AV; Sprooten E; Strike LT; Teumer A; Thomson R; Tordesillas-Gutierrez D; Toro R; Trabzuni D; Vaidya D; Van der Grond J; Van der Meer D; Van Donkelaar MMJ; Van Eijk KR; Van Erp TGM; Van Rooij D; Walton E; Westlye LT; Whelan CD; Windham BG; Winkler AM; Woldehawariat G; Wolf C; Wolfers T; Xu B; Yanek LR; Yang J; Zijdenbos A; Zwiers MP; Agartz I; Aggarwal NT; Almasy L; Ames D; Amouyel P; Andreassen OA; Arepalli S; Assareh AA; Barral S; Bastin ME; Becker DM; Becker JT; Bennett DA; Blangero J; van Bokhoven H; Boomsma DI; Brodaty H; Brouwer RM; Brunner HG; Buckner RL; Buitelaar JK; Bulayeva KB; Cahn W; Calhoun VD; Cannon DM; Cavalleri GL; Chen C; Cheng C-Y; Cichon S; Cookson MR; Corvin A; Crespo-Facorro B; Curran JE; Czisch M; Dale AM; Davies GE; De Geus EJC; De Jager PL; de Zubicaray GI; Delanty N; Depondt C; DeStefano AL; Dillman A; Djurovic S; Donohoe G; Drevets WC; Duggirala R; Dyer TD; Erk S; Espeseth T; Evans DA; Fedko I; Fernandez G; Ferrucci L; Fisher SE; Fleischman DA; Ford I; Foroud TM; Fox PT; Francks C; Fukunaga M; Gibbs JR; Glahn DC; Gollub RL; Goring HHH; Grabe HJ; Green RC; Gruber O; Gudnason V; Guelfi S; Hansell NK; Hardy J; Hartman CA; Hashimoto R; Hegenscheid K; Heinz A; Le Hellard S; Hernandez DG; Heslenfeld DJ; Ho B-C; Hoekstra PJ; Hoffmann W; Hofman A; Holsboer F; Homuth G; Hosten N; Hottenga J-J; Pol HEH; Ikeda M; Ikram MK; Jack CRJ; Jenldnson M; Johnson R; Jonsson EG; Jukema JW; Kahn RS; Kanai R; Kloszewska I; Knopman DS; Kochunov P; Kwok JB; Lawrie SM; Lemaitre H; Liu X; Longo DL; Longstreth WTJ; Lopez OL; Lovestone S; Martinez O; Martinot J-L; Mattay VS; McDonald C; McIntosh AM; McMahon KL; McMahon FJ; Mecocci P; Melle I; Meyer-Lindenberg A; Mohnke S; Montgomery GW; Morris DW; Mosley TH; Muhleisen TW; Mueller-Myhsok B; Nalls MA; Nauck M; Nichols TE; Niessen WJ; Noethen MM; Nyberg L; Ohi K; Olvera RL; Ophoff RA; Pandolfo M; Paus T; Pausova Z; Penninx BWJH; Pike GB; Potkin SG; Psaty BM; Reppermund S; Rietschel M; Roffman JL; Romanczuk-Seiferth N; Rotter JI; Ryten M; Sacco RL; Sachdev PS; Saykin AJ; Schmidt R; Schofield PR; Sigurdsson S; Simmons A; Singleton A; Sisodiya SM; Smith C; Smoller JW; Soininen H; Srikanth V; Steen VM; Stott DJ; Sussmann JE; Thalamuthu A; Tiemeier H; Toga AW; Traynor BJ; Troncoso J; Turner JA; Tzourio C; Uitterlinden AG; Hernandez MCV; Van der Brug M; Van der Lugt A; Van der Wee NJA; Van Duijn CM; Van Haren NEM; Van't Ent D; Van Tol MJ; Vardarajan BN; Veltman DJ; Vernooij MW; Voelzke H; Walter H; Wardlaw JM; Wassink TH; Weale ME; Weinberger DR; Weiner MW; Wen W; Westman E; White T; Wong TY; Wright CB; Zielke HR; Zonderman AB; Deary IJ; DeCarli C; Schmidt H; Martin NG; De Craen AJM; Wright MJ; Launer LJ; Schumann G; Fornage M; Franke B; Debette S; Medland SE; Ikram MA; Thompson PM
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2016;55(2):625-644
Cerebrospinal Fluid Biomarkers for the Differential Diagnosis between Alzheimer's Disease and Frontotemporal Lobar Degeneration: Systematic Review, HSROC Analysis, and Confounding Factors
Rivero-Santana A; Ferreira D; Perestelo-Perez L; Westman E; Wahlund L-O; Sarria A; Serrano-Aguilar P
Article: BEHAVIOURAL BRAIN RESEARCH. 2016;311:375-383
Different reserve proxies confer overlapping and unique endurance to cortical thinning in healthy middle-aged adults
Ferreira D; Bartres-Faz D; Nygren L; Rundkvist LJ; Molina Y; Machado A; Junque C; Barroso J; Westman E
Article: EUROPEAN RADIOLOGY. 2016;26(8):2597-2610
Quantitative validation of a visual rating scale for frontal atrophy: associations with clinical status, APOE e4, CSF biomarkers and cognition
Ferreira D; Cavallin L; Granberg T; Lindberg O; Aguilar C; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Simmons A; Wahlund L-O; Westman E
Article: CEREBRAL CORTEX. 2016;26(8):3476-3493
Disrupted Network Topology in Patients with Stable and Progressive Mild Cognitive Impairment and Alzheimer's Disease
Pereira JB; Mijalkov M; Kakaei E; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Spenger C; Lovestone S; Simmons A; Wahlund L-O; Volpe G; Westman E
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2016;8(1):30
Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device
Eyjolfsdottir H; Eriksdotter M; Linderoth B; Lind G; Juliusson B; Kusk P; Almkvist O; Andreasen N; Blennow K; Ferreira D; Westman E; Nennesmo I; Karami A; Darreh-Shori T; Kadir A; Nordberg A; Sundstrom E; Wahlund L-O; Wall A; Wiberg M; Winblad B; Seiger A; Wahlberg L; Almqvist P
Article: NEUROLOGY. 2016;86(19):1754-1761
Myo-inositol changes precede amyloid pathology and relate to APOE genotype in Alzheimer disease
Voevodskaya O; Sundgren PC; Strandberg O; Zetterberg H; Minthon L; Blennow K; Wahlund L-O; Westman E; Hansson O
Article: NEUROBIOLOGY OF AGING. 2016;40:68-77
The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume
Lupton MK; Strike L; Hansell NK; Wen W; Mather KA; Armstrong NJ; Thalamuthu A; McMahon KL; de Zubicaray GI; Assareh AA; Simmons A; Proitsi P; Powell JF; Montgomery GW; Hibar DP; Westman E; Tsolaki M; Kloszewska I; Soininen H; Mecocci P; Velas B; Lovestone S; Brodaty H; Ames D; Trollor JN; Martin NG; Thompson PM; Sachdev PS; Wright MJ
Article: CUREUS. 2016;8(3):e544
Manual Planimetry of the Medial Temporal Lobe Versus Automated Volumetry of the Hippocampus in the Diagnosis of Alzheimer's Disease.
Menéndez González M; Suárez-Sanmartin E; García C; Martínez-Camblor P; Westman E; Simmons A
Article: BRAIN TOPOGRAPHY. 2016;29(2):296-307
The Effect of Age Correction on Multivariate Classification in Alzheimer's Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects
Falahati F; Ferreira D; Soininen H; Mecocci P; Vellas B; Tsolaki M; Koszewska I; Lovestone S; Eriksdotter M; Wahlund L-O; Simmons A; Westman E
Article: NATURE NEUROSCIENCE. 2016;19(3):420-431
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
Franke B; Stein JL; Ripke S; Anttila V; Hibar DP; van Hulzen KJE; Arias-Vasquez A; Smoller JW; Nichols TE; Neale MC; McIntosh AM; Lee P; McMahon FJ; Meyer-Lindenberg A; Mattheisen M; Andreassen OA; Gruber O; Sachdev PS; Roiz-Santianez R; Saykin AJ; Ehrlich S; Mather KA; Turner JA; Wright MJ; O'Donovan MC; Thompson PM; Neale BM; Medland SE; Sullivan PF
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2016;42(1-2):80-92
Electroencephalography Is a Good Complement to Currently Established Dementia Biomarkers
Ferreira D; Jelic V; Cavallin L; Oeksengaard A-R; Snaedal J; Hogh P; Andersen BB; Naik M; Engedal K; Westman E; Wahlund L-O
Article: SCIENTIFIC REPORTS. 2015;5:16404
Early astrocytosis in autosomal dominant Alzheimer's disease measured in vivo by multi-tracer positron emission tomography
Scholl M; Carter SF; Westman E; Rodriguez-Vieitez E; Almkvist O; Thordardottir S; Wall A; Graff C; Langstrom B; Nordberg A
Article: EUROPEAN RADIOLOGY. 2015;25(11):3151-3160
Automated CT-based segmentation and quantification of total intracranial volume
Aguilar C; Edholm K; Simmons A; Cavallin L; Muller S; Skoog I; Larsson E-M; Axelsson R; Wahlund L-O; Westman E
Article: ALZHEIMER'S AND DEMENTIA. 2015;11(11):1316-1328
Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease
Karami A; Eyjolfsdottir H; Vijayaraghavan S; Lind G; Almqvist P; Kadir A; Linderoth B; Andreasen N; Blennow K; Wall A; Westman E; Ferreira D; Wiberg MK; Wahlund L-O; Seiger A; Nordberg A; Wahlberg L; Darreh-Taher T; Eriksdotter M
Article: BRAIN TOPOGRAPHY. 2015;28(5):746-759
Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease in Two Independent Cohorts
Khan W; Westman E; Jones N; Wahlund L-O; Mecocci P; Vellas B; Tsolaki M; Koszewska I; Soininen H; Spenger C; Lovestone S; Muehlboeck J-S; Simmons A
Article: JOURNAL OF INTERNAL MEDICINE. 2015;278(3):277-290
Practical cut-offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment
Ferreira D; Cavallin L; Larsson E-M; Muehlboeck J-S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Simmons A; Wahlund L-O; Westman E
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2015;47(4):977-984
Tract Based Spatial Statistic Reveals No Differences in White Matter Microstructural Organization between Carriers and Non-Carriers of the APOE ε4 and ε2 Alleles in Young Healthy Adolescents
Dell'Acqua F; Khan W; Gottlieb N; Giampietro V; Ginestet C; Bouls D; Newhouse S; Dobson R; Banaschewski T; Barker GJ; Bokde ALW; Buechel C; Conrod P; Flor H; Frouin V; Garavan H; Gowlands P; Heinz A; Lemaitre H; Nees F; Paus T; Pausova Z; Rietschel M; Smolka MN; Stroehle A; Gallinat J; Westman E; Schumann G; Lovestone S; Simmons A
Article: HUMAN BRAIN MAPPING. 2015;36(8):2980-2995
Aberrant cerebral network topology and mild cognitive impairment in early Parkinson's disease
Pereira JB; Aarsland D; Ginestet CE; Lebedev AV; Wahlund L-O; Simmons A; Volpe G; Westman E
Article: JOURNAL OF INTERNAL MEDICINE. 2015;278(2):211-218
White matter changes in familial Alzheimer's disease
Li X; Westman E; Stahlbom AK; Thordardottir S; Almkvist O; Blennow K; Wahlund L-O; Graff C
Article: TRANSLATIONAL PSYCHIATRY. 2015;5(6):e584
Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes
Kiddle SJ; Steves CJ; Mehta M; Simmons A; Xu X; Newhouse S; Sattlecker M; Ashton NJ; Bazenet C; Killick R; Adnan J; Westman E; Nelson S; Soininen H; Kloszewska I; Mecocci P; Tsolaki M; Vellas B; Curtis C; Breen G; Williams SCR; Lovestone S; Spector TD; Dobson RJB
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2015;30(5):531-538
A voxel-based morphometry comparison of the 3.0T ADNI-1 and ADNI-2 volumetric MRI protocols
Brunton S; Gunasinghe C; Jones N; Kempton MJ; Westman E; Simmons A
Article: NATURE. 2015;520(7546):224-229
Common genetic variants influence human subcortical brain structures
Hibar DP; Stein JL; Renteria ME; Arias-Vasquez A; Desrivieres S; Jahanshad N; Toro R; Wittfeld K; Abramovic L; Andersson M; Aribisala BS; Armstrong NJ; Bernard M; Bohlken MM; Boks MP; Bralten J; Brown AA; Chakravarty MM; Chen Q; Ching CRK; Cuellar-Partida G; den Braber A; Giddaluru S; Goldman AL; Grimm O; Guadalupe T; Hass J; Woldehawariat G; Holmes AJ; Hoogman M; Janowitz D; Jia T; Kim S; Klein M; Kraemer B; Lee PH; Loohuis LMO; Luciano M; Macare C; Mather KA; Mattheisen M; Milaneschi Y; Nho K; Papmeyer M; Ramasamy A; Risacher SL; Roiz-Santianez R; Rose EJ; Salami A; Saemann PG; Schmaal L; Schork AJ; Shin J; Strike LT; Teumer A; van Donkelaar MMJ; van Eijk KR; Walters RK; Westlye LT; Whelan CD; Winkler AM; Zwiers MP; Alhusaini S; Athanasiu L; Ehrlich S; Hakobjan MMH; Hartberg CB; Haukvik UK; Heister AJGAM; Hoehn D; Kasperaviciute D; Liewald DCM; Lopez LM; Makkinje RRR; Matarin M; Naber MAM; McKay DR; Needham M; Nugent AC; Puetz B; Royle NA; Shen L; Sprooten E; Trabzuni D; van der Marel SSL; van Hulzen KJE; Walton E; Wolf C; Almasy L; Ames D; Arepalli S; Assareh AA; Bastin ME; Brodaty H; Bulayeva KB; Carless MA; Cichon S; Corvin A; Curran JE; Czisch M; de Zubicaray GI; Dillman A; Duggirala R; Dyer TD; Erk S; Fedko IO; Ferrucci L; Foroud TM; Fox PT; Fukunaga M; Gibbs JR; Goering HHH; Green RC; Guelfi S; Hansell NK; Hartman CA; Hegenscheid K; Heinz A; Hernandez DG; Heslenfeld DJ; Hoekstra PJ; Holsboer F; Homuth G; Hottenga J-J; Ikeda M; Jack CRJ; Jenkinson M; Johnson R; Kanai R; Keil M; Kent JWJ; Kochunov P; Kwok JB; Lawrie SM; Liu X; Longo DL; McMahon KL; Meisenzah E; Melle I; Mahnke S; Montgomery GW; Mostert JC; Muehleisen TW; Nalls MA; Nichols TE; Nilsson LG; Noethen MM; Ohi K; Olvera RL; Perez-Iglesias R; Pike GB; Potkin SG; Reinvang I; Reppermund S; Rietschel M; Romanczuk-Seiferth N; Rosen GD; Rujescu D; Schnell K; Schofield PR; Smith C; Steen VM; Sussmann JE; Thalamuthu A; Toga AW; Traynor BJ; Troncoso J; Turner JA; Valdes Hernandez MC; van't Ent D; van der Brug M; van der Wee NJA; van Tol M-J; Veltman DJ; Wassink TH; Westman E; Zielke RH; Zonderman AB; Ashbrook DG; Hager R; Lu L; McMahon FJ; Morris DW; Williams RW; Brunner HG; Buckner RL; Buitelaar JK; Cahn W; Calhoun VD; Cavalleri GL; Crespo-Facorro B; Dale AM; Davies GE; Delanty N; Depondt C; Djurovic S; Drevets WC; Espeseth T; Gollub RL; Ho B-C; Hoffman W; Hosten N; Kahn RS; Le Hellard S; Meyer-Lindenberg A; Mueller-Myhsok B; Nauck M; Nyberg L; Pandolfo M; Penninx BWJH; Roffman JL; Sisodiya SM; Smoller JW; van Bokhoven H; van Haren NEM; Voelzke H; Walter H; Weiner MW; Wen W; White T; Agartz I; Andreassen OA; Blangero J; Boomsma DI; Brouwer RM; Cannon DM; Cookson MR; de Geus EJC; Deary IJ; Donohoe G; Fernandez G; Fisher SE; Francks C; Glahn DC; Grabe HJ; Gruber O; Hardy J; Hashimoto R; Pol HEH; Joensson EG; Kloszewska I; Lovestone S; Mattay VS; Mecocci P; McDonald C; McIntosh AM; Ophoff RA; Paus T; Pausova Z; Ryten M; Sachdev PS; Saykin AJ; Simmons A; Singleton A; Soininen H; Wardlaw JM; Weale ME; Weinberger DR; Adams HHH; Launer LJ; Seiler S; Schmidt R; Chauhan G; Satizabal CL; Becker JT; Yanek L; van der Lee SJ; Ebling M; Fischl B; Longstreth WTJ; Greve D; Schmidt H; Nyquist P; Vinke LN; van Duijn CM; Xue L; Mazoyer B; Bis JC; Gudnason V; Seshadri S; Ikram MA; Martin NG; Wright MJ; Schumann G; Franke B; Thompson PMJ; Medland SE
Article: PSYCHOLOGICAL MEDICINE. 2015;45(6):1219-1228
The influence of negative life events on hippocampal and amygdala volumes in old age: a life-course perspective
Gerritsen L; Kalpouzos G; Westman E; Simmons A; Wahlund L-O; Backman L; Fratiglioni L; Wang H-X
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2015;45(3):851-864
Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts
Khondoker M; Newhouse S; Westman E; Muehlboeck J-S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Dobson R; Simmons A
Article: JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY. 2015;28(1):40-48
Medial Temporal Lobe Atrophy and Depressive Symptoms in Elderly Patients With and Without Alzheimer Disease
Enache D; Cavallin L; Lindberg O; Farahmand B; Kramberger MG; Westman E; Jelic V; Eriksdotter M; Ballard C; Winblad B; Wahlund L-O; Aarsland D
Article: AGING CELL. 2015;14(1):122-129
Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease
Maioli S; Lodeiro M; Merino-Serrais P; Falahati F; Khan W; Puerta E; Codita A; Rimondini R; Ramirez MJ; Simmons A; Gil-Bea F; Westman E; Cedazo-Minguez A
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2015;39(1-2):81-91
The Use of MRI, CT and Lumbar Puncture in Dementia Diagnostics: Data from the SveDem Registry
Falahati F; Fereshtehnejad S-M; Religa D; Wahlund L-O; Westman E; Eriksdotter M
Article: PLOS ONE. 2015;10(8):e0134368
A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease
Khan W; Aguilar C; Kiddle SJ; Doyle O; Thambisetty M; Muehlboeck S; Sattlecker M; Newhouse S; Lovestone S; Dobson R; Giampietro V; Westman E; Simmons A
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2014;43(4):1393-1402
Preclinical Cerebrospinal Fluid and Volumetric Magnetic Resonance Imaging Biomarkers in Swedish Familial Alzheimer's Disease
Thordardottir S; Stahlbom AK; Ferreira D; Almkvist O; Westman E; Zetterberg H; Eriksdotter M; Blennow K; Graff C
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2014;43(3):1059-1072
Brain Changes in Alzheimer's Disease Patients with Implanted Encapsulated Cells Releasing Nerve Growth Factor
Ferreira D; Westman E; Eyjolfsdottir H; Almqvist P; Lind G; Linderoth B; Seiger A; Blennow K; Karami A; Darreh-Shori T; Wiberg M; Simmons A; Wahlund L-O; Wahlberg L; Eriksdotter M
Article: ALZHEIMER'S AND DEMENTIA. 2014;10(6):799-807.e2
Plasma proteins predict conversion to dementia from prodromal disease
Hye A; Riddoch-Contreras J; Baird AL; Ashton NJ; Bazenet C; Leung R; Westman E; Simmons A; Dobson R; Sattlecker M; Lupton M; Lunnon K; Keohane A; Ward M; Pike I; Zucht HD; Pepin D; Zheng W; Tunnicliffe A; Richardson J; Gauthier S; Soininen H; Kloszewska I; Mecocci P; Tsolaki M; Vellas B; Lovestone S
Article: ALZHEIMER'S AND DEMENTIA. 2014;10(6):724-734
Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology
Sattlecker M; Kiddle SJ; Newhouse S; Proitsi P; Nelson S; Williams S; Johnston C; Killick R; Simmons A; Westman E; Hodges A; Soininen H; Kloszewska I; Mecocci P; Tsolaki M; Vellas B; Lovestone S; Dobson RJB
Article: JOURNAL OF NEUROIMMUNOLOGY. 2014;274(1-2):149-154
Multiple sclerosis patients lacking oligoclonal bands in the cerebrospinal fluid have less global and regional brain atrophy.
Ferreira D; Voevodskaya O; Imrell K; Stawiarz L; Spulber G; Wahlund L-O; Hillert J; Westman E; Karrenbauer VD
Article: JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY. 2014;85(8):928-933
Structural brain changes associated with depressive symptoms in the elderly with Alzheimer's disease
Lebedeva A; Westman E; Lebedev AV; Li X; Winblad B; Simmons A; Wahlund L-O; Aarsland D
Article: NEUROLOGY. 2014;82(22):2017-2025
Initial cognitive decline is associated with cortical thinning in early Parkinson disease.
Pereira JB; Svenningsson P; Weintraub D; Brønnick K; Lebedev A; Westman E; Aarsland D
Article: NEUROBIOLOGY OF AGING. 2014;35(5):1086-1094
Cognitive decline is mediated by gray matter changes during middle age
Ferreira D; Molina Y; Machado A; Westman E; Wahlund L-O; Nieto A; Correia R; Junque C; Diaz-Flores L; Barroso J
Article: HIPPOCAMPUS. 2014;24(4):403-414
Regional Vulnerability of Hippocampal Subfields to Aging Measured by Structural and Diffusion MRI
Pereira JB; Valls-Pedret C; Ros E; Palacios E; Falcon C; Bargallo N; Bartres-Faz D; Wahlund L-O; Westman E; Junque C
Article: JOURNAL OF INTERNAL MEDICINE. 2014;275(4):418-427
The association between biomarkers in cerebrospinal fluid and structural changes in the brain in patients with Alzheimer's disease
Li X; Li T-Q; Andreasen N; Wiberg MK; Westman E; Wahlund L-O
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2014;40(1):37-43
No Differences in Hippocampal Volume between Carriers and Non-Carriers of the ApoE ε4 and ε2 Alleles in Young Healthy Adolescents
Khan W; Giampietro V; Ginestet C; Dell'Acqua F; Bouls D; Newhouse S; Dobson R; Banaschewski T; Barker GJ; Bokde ALW; Buechel C; Conrod P; Flor H; Frouin V; Garavan H; Gowland P; Heinz A; Ittermann B; Lemaitrek H; Nees F; Paus T; Pausova Z; Rietschel M; Smolka MN; Stroehle A; Gallinat J; Westman E; Schumann G; Lovestone S; Simmons A
Article: JOURNAL OF INTERNAL MEDICINE. 2014;275(3):317-330
Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut-offs
Pereira JB; Cavallin L; Spulber G; Aguilar C; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Spenger C; Aarsland D; Lovestone S; Simmons A; Wahlund L-O; Westman E
Article: FRONTIERS IN NEUROINFORMATICS. 2014;7:49
The HiveDB image data management and analysis framework
Muehlboeck J-S; Westman E; Simmons A
Article: FRONTIERS IN SYSTEMS NEUROSCIENCE. 2014;8:45
Large-scale resting state network correlates of cognitive impairment in Parkinson's disease and related dopaminergic deficits.
Lebedev AV; Westman E; Simmons A; Lebedeva A; Siepel FJ; Pereira JB; Aarsland D
Article: FRONTIERS IN AGING NEUROSCIENCE. 2014;6:264
The effects of intracranial volume adjustment approaches on multiple regional MRI volumes in healthy aging and Alzheimer's disease
Voevodskaya O; Simmons A; Nordenskjold R; Kullberg J; Ahlstrom H; Lind L; Wahlund L-O; Larsson E-M; Westman E
Article: PLOS ONE. 2014;9(8):e105542
Predicting Progression of Alzheimer's Disease Using Ordinal Regression
Doyle OM; Westman E; Marquand AF; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Williams SCR; Simmons A
Article: FRONTIERS IN AGING NEUROSCIENCE. 2014;6:145
Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort
Aguilar C; Muehlboeck J-S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Wahlund L-O; Simmons A; Westman E
Article: NEUROIMAGE: CLINICAL. 2014;6:115-125
Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness
Lebedev AV; Westman E; Van Westen GJP; Kramberger MG; Lundervold A; Aarsland D; Soininen H; Kloszewska I; Mecocci P; Tsolaki M; Vellas B; Lovestone S; Simmons A
Article: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 2014;22(1):4-13.e1
Cortical Changes Associated with Depression and Antidepressant Use in Alzheimer and Lewy Body Dementia: An MRI Surface-based Morphometric Study
Lebedev AV; Beyer MK; Fritze F; Westman E; Ballard C; Aarsland D
Article: JOURNAL OF INTERNAL MEDICINE. 2013;273(6):602-621
Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol
Mangialasche F; Westman E; Kivipelto M; Muehlboeck J-S; Cecchetti R; Baglioni M; Tarducci R; Gobbi G; Floridi P; Soininen H; Kloszewska I; Tsolaki M; Vellas B; Spenger C; Lovestone S; Wahlund L-O; Simmons A; Mecocci P
Article: PSYCHIATRY RESEARCH. 2013;212(2):89-98
Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment
Aguilar C; Westman E; Muehlboeck J-S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Spenger C; Simmons A; Wahlund L-O
Article: JOURNAL OF INTERNAL MEDICINE. 2013;273(4):396-409
An MRI-based index to measure the severity of Alzheimer's disease-like structural pattern in subjects with mild cognitive impairment
Spulber G; Simmons A; Muehlboeck J-S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Spenger C; Lovestone S; Wahlund L-O; Westman E
Article: JOURNAL OF NEUROLOGY. 2013;260(4):1104-1115
Multivariate classification of patients with Alzheimer's and dementia with Lewy bodies using high-dimensional cortical thickness measurements: an MRI surface-based morphometric study
Lebedev AV; Westman E; Beyer MK; Kramberger MG; Aguilar C; Pirtosek Z; Aarsland D
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2013;33(3):755-766
Entorhinal Cortex Thickness Predicts Cognitive Decline in Alzheimer's Disease
Velayudhan L; Proitsi P; Westman E; Muehlboeck J-S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Spenger C; Hodges A; Powell J; Lovestone S; Simmons A
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA. 2013;3(1):446-458
CERAD Neuropsychological Total Scores Reflect Cortical Thinning in Prodromal Alzheimer's Disease.
Paajanen T; Hänninen T; Aitken A; Hallikainen M; Westman E; Wahlund L-O; Sobow T; Mecocci P; Tsolaki M; Vellas B; Muehlboeck S; Spenger C; Lovestone S; Simmons A; Soininen H; AddNeuroMed Consortium
Article: SCIENTIFIC REPORTS. 2013;3:1339
Ratio of Aβ42/P-tau_181p in CSF is associated with aberrant default mode network in AD
Li X; Li T-Q; Andreasen N; Wiberg MK; Westman E; Wahlund L-O
Article: BRAIN TOPOGRAPHY. 2013;26(1):9-23
Regional Magnetic Resonance Imaging Measures for Multivariate Analysis in Alzheimer's Disease and Mild Cognitive Impairment
Westman E; Aguilar C; Muehlboeck J-S; Simmons A
Article: NEUROPSYCHIATRIC DISEASE AND TREATMENT. 2013;9:927-935
Demography, diagnostics, and medication in dementia with Lewy bodies and Parkinson's disease with dementia: data from the Swedish Dementia Quality Registry (SveDem)
Fereshtehnejad S-M; Religa D; Westman E; Aarsland D; Lokk J; Eriksdotter M
Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2012;322(1-2):211-216
Multispectral MRI segmentation of age related white matter changes using a cascade of support vector machines
Damangir S; Manzouri A; Oppedal K; Carlsson S; Firbank MJ; Sonnesyn H; Tysnes O-B; O'Brien JT; Beyer MK; Westman E; Aarsland D; Wahlund L-O; Spulber G
Article: AMERICAN JOURNAL OF NEURORADIOLOGY. 2012;33(10):1957-1963
A Comparison Between Volumetric Data Generated by Voxel-Based Morphometry and Manual Parcellation of Multimodal Regions of the Frontal Lobe
Lindberg O; Manzouri A; Westman E; Wahlund L-O
Article: NEURORADIOLOGY. 2012;54(9):929-938
Education increases reserve against Alzheimer's disease-evidence from structural MRI analysis
Liu Y; Julkunen V; Paajanen T; Westman E; Wahlund L-O; Aitken A; Sobow T; Mecocci P; Tsolaki M; Vellas B; Muehlboeck S; Spenger C; Lovestone S; Simmons A; Soininen H
Article: NEUROIMAGE. 2012;62(1):229-238
Combining MRI and CSF measures for classification of Alzheimer's disease and prediction of mild cognitive impairment conversion
Westman E; Muehlboeck J-S; Simmons A
Article: FRONTIERS IN AGING NEUROSCIENCE. 2012;4:32
Is the subcallosal medial prefrontal cortex a common site of atrophy in Alzheimer's disease and frontotemporal lobar degeneration?
Lindberg O; Westman E; Karlsson S; Ostberg P; Svensson LA; Simmons A; Wahlund L-O
Article: PLOS ONE. 2012;7(9):e44260
Plasma Based Markers of [¹¹C] PiB-PET Brain Amyloid Burden
Kiddle SJ; Thambisetty M; Simmons A; Riddoch-Contreras J; Hye A; Westman E; Pike I; Ward M; Johnston C; Lupton MK; Lunnon K; Soininen H; Kloszewska I; Tsolaki M; Vellas B; Mecocci P; Lovestone S; Newhouse S; Dobson R
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2011;26:307-319
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy for Detection of Early Alzheimer's Disease
Westman E; Wahlund L-O; Foy C; Poppe M; Cooper A; Murphy D; Spenger C; Lovestone S; Simmons A
Article: NEUROIMAGE. 2011;58(3):818-828
AddNeuroMed and ADNI: Similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America
Westman E; Simmons A; Muehlboeck J-S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Weiner MW; Lovestone S; Spenger C; Wahlund L-O
Article: NEUROBIOLOGY OF AGING. 2011;32(8):1388-1399
Glucose metabolism and PIB binding in carriers of a His163Tyr presenilin 1 mutation
Scholl M; Almkvist O; Axelman K; Stefanova E; Wall A; Westman E; Langstrom B; Lannfelt L; Graff C; Nordberg A
Article: NEUROBIOLOGY OF AGING. 2011;32(7):1198-1206
Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups-The AddNeuroMed study
Liu Y; Paajanen T; Zhang Y; Westman E; Wahlund L-O; Simmons A; Tunnard C; Sobow T; Mecocci P; Tsolaki M; Vellas B; Muehlboeck S; Evans A; Spenger C; Lovestone S; Soininen H
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2011;33(4):678-688
1H-MRS in spinal cord injury: acute and chronic metabolite alterations in rat brain and lumbar spinal cord
Erschbamer M; Oberg J; Westman E; Sitnikov R; Olson L; Spenger C
Article: NEUROIMAGE. 2011;54(2):1178-1187
Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controls
Westman E; Simmons A; Zhang Y; Muehlboeck J-S; Tunnard C; Liu Y; Collins L; Evans A; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Spenger C; Wahlund L-O
Article: PLOS ONE. 2011;6(7):e22506
Sensitivity and Specificity of Medial Temporal Lobe Visual Ratings and Multivariate Regional MRI Classification in Alzheimer's Disease
Westman E; Cavallin L; Muehlboeck J-S; Zhang Y; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Spenger C; Lovestone S; Simmons A; Wahlund L-O
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2011;26(1):75-82
The AddNeuroMed framework for multi-centre MRI assessment of Alzheimer's disease : experience from the first 24 months
Simmons A; Westman E; Muehlboeck S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Wahlund L-O; Soininen H; Lovestone S; Evans A; Spenger C
Article: PLOS ONE. 2011;6(12):e28527
Plasma Biomarkers of Brain Atrophy in Alzheimer's Disease
Thambisetty M; Simmons A; Hye A; Campbell J; Westman E; Zhang Y; Wahlund L-O; Kinsey A; Causevic M; Killick R; Kloszewska I; Mecocci P; Soininen H; Tsolaki M; Vellas B; Spenger C; Lovestone S
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2010;22(1):171-181
Combining MRI and MRS to Distinguish Between Alzheimer's Disease and Healthy Controls
Westman E; Wahlund L-O; Foy C; Poppe M; Cooper A; Murphy D; Spenger C; Lovestone S; Simmons A
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2010;21(3):947-966
Effect of APOE ε4 Allele on Cortical Thicknesses and Volumes: The AddNeuroMed Study
Liu Y; Paajanen T; Westman E; Wahlund L-O; Simmons A; Tunnard C; Sobow T; Proitsi P; Powell J; Mecocci P; Tsolaki M; Vellas B; Muehlboeck S; Evans A; Spenger C; Lovestone S; Soininen H
Article: NEUROBIOLOGY OF AGING. 2010;31(8):1375-1385
Analysis of regional MRI volumes and thicknesses as predictors of conversion from mild cognitive impairment to Alzheimer's disease
Liu Y; Paajanen T; Zhang Y; Westman E; Wahlund L-O; Simmons A; Tunnard C; Sobow T; Mecocci P; Tsolaki M; Vellas B; Muehlboeck S; Evans A; Spenger C; Lovestone S; Soininen H
Article: ARCHIVES OF GENERAL PSYCHIATRY. 2010;67(7):739-748
Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease
Thambisetty M; Simmons A; Velayudhan L; Hye A; Campbell J; Zhang Y; Wahlund L-O; Westman E; Kinsey A; Guntert A; Proitsi P; Powell J; Causevic M; Killick R; Lunnon K; Lynham S; Broadstock M; Choudhry F; Howlett DR; Williams RJ; Sharp SI; Mitchelmore C; Tunnard C; Leung R; Foy C; O'Brien D; Breen G; Furney SJ; Ward M; Kloszewska I; Mecocci P; Soininen H; Tsolaki M; Vellas B; Hodges A; Murphy DGM; Parkins S; Richardson JC; Resnick SM; Ferrucci L; Wong DF; Zhou Y; Muehlboeck S; Evans A; Francis PT; Spenger C; Lovestone S
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2010;30(3):229-237
APOE ε2 Allele Is Associated with Larger Regional Cortical Thicknesses and Volumes
Liu Y; Paajanen T; Westman E; Zhang Y; Wahlund L-O; Simmons A; Tunnard C; Sobow T; Proitsi P; Powell J; Mecocci P; Tsolaki M; Vellas B; Muehlboeck S; Evans A; Spenger C; Lovestone S; Soininen H
Article: BMC NEUROSCIENCE. 2009;10:33
In vivo ¹H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment
Westman E; Spenger C; Oberg J; Reyer H; Pahnke J; Wahlund L-O
Article: NEUROBIOLOGY OF AGING. 2008;29(9):1423-1433
Age related changes in brain metabolites observed by ¹H MRS in APP/PS1 mice
Oberg J; Spenger C; Wang F-H; Andersson A; Westman E; Skoglund P; Sunnemark D; Norinder U; Klason T; Wahlund L-O; Lindberg M
Article: EXPERIMENTAL NEUROLOGY. 2008;209(1):155-160
Reorganization of sensory processing below the level of spinal cord injury as revealed by fMRl
Endo T; Spenger C; Westman E; Tominaga T; Olson L
Article: NEUROBIOLOGY OF DISEASE. 2007;26(1):221-228
Carbamazepine treatment recovered low N-acetylaspartate plus N-acetylaspartylglutamate (tNAA) levels in the megencephaly mouse BALB/cByJ-Kv1.1^mceph/mceph
Westman E; Spenger C; Wahlund L-O; Lavebratt C
Article: BMC NEUROSCIENCE. 2007;8:10
Kv1.1 null mice have enlarged hippocampus and ventral cortex
Persson A-S; Westman E; Wang F-H; Khan FH; Spenger C; Lavebratt C
Article: JOURNAL OF NEUROSCIENCE. 2006;26(23):6330-6336
Blood oxygenation level-dependent visualization of synaptic relay stations of sensory pathways along the neuroaxis in response to graded sensory stimulation of a limb
Lilja J; Endo T; Hofstetter C; Westman E; Young J; Olson L; Spenger C
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All other publications

Review: BRAIN IMAGING AND BEHAVIOR. 2024;:1-15
Unveiling the hippocampal subfield changes across the Alzheimer's disease continuum: a systematic review of neuroimaging studies
Zilioli A; Pancaldi B; Baumeister H; Busi G; Misirocchi F; Mutti C; Florindo I; Morelli N; Mohanty R; Berron D; Westman E; Spallazzi M
Preprint: MEDRXIV. 2024;MEDRXIV
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
García-Marín LM; Campos AI; Diaz-Torres S; Rabinowitz JA; Ceja Z; Mitchell BL; Grasby KL; Thorp JG; Agartz I; Alhusaini S; Ames D; Amouyel P; Andreassen OA; Arfanakis K; Vasquez AA; Armstrong NJ; Athanasiu L; Bastin ME; Beiser AS; Bennett DA; Bis JC; Boks MP; Boomsma DI; Brodaty H; Brouwer RM; Buitelaar JK; Burkhardt R; Cahn W; Calhoun VD; Carmichael OT; Chakravarty M; Chen Q; Ching CRK; Cichon S; Crespo-Facorro B; Crivello F; Dale AM; Smith GD; de Geus EJ; De Jager PL; de Zubicaray GI; Debette S; DeCarli C; Depondt C; Desrivières S; Djurovic S; Ehrlich S; Erk S; Espeseth T; Fernández G; Filippi I; Fisher SE; Fleischman DA; Fletcher E; Fornage M; Forstner AJ; Francks C; Franke B; Ge T; Goldman AL; Grabe HJ; Green RC; Grimm O; Groenewold NA; Gruber O; Gudnason V; Håberg AK; Haukvik UK; Heinz A; Hibar DP; Hilal S; Himali JJ; Ho B-C; Hoehn DF; Hoekstra PJ; Hofer E; Hoffmann W; Holmes AJ; Homuth G; Hosten N; Ikram MK; Ipser JC; Jack CR; Jahanshad N; Jönsson EG; Kahn RS; Kanai R; Klein M; Knol MJ; Launer LJ; Lawrie SM; Hellard SL; Lee PH; Lemaître H; Li S; Liewald DC; Lin H; Longstreth WT; Lopez OL; Luciano M; Maillard P; Marquand AF; Martin NG; Martinot J-L; Mather KA; Mattay VS; McMahon KL; Mecocci P; Melle I; Meyer-Lindenberg A; Mirza-Schreiber N; Milaneschi Y; Mosley TH; Mühleisen TW; Müller-Myhsok B; Muñoz Maniega S; Nauck M; Nho K; Niessen WJ; Nöthen MM; Nyquist PA; Oosterlaan J; Pandolfo M; Paus T; Pausova Z; Penninx BW; Pike GB; Psaty BM; Pütz B; Reppermund S; Rietschel MD; Risacher SL; Romanczuk-Seiferth N; Romero-Garcia R; Roshchupkin GV; Rotter JI; Sachdev PS; Sämann PG; Saremi A; Sargurupremraj M; Saykin AJ; Schmaal L; Schmidt H; Schmidt R; Schofield PR; Scholz M; Schumann G; Schwarz E; Shen L; Shin J; Sisodiya SM; Smith AV; Smoller JW; Soininen HS; Steen VM; Stein DJ; Stein JL; Thomopoulos SI; Toga AW; Tordesillas-Gutiérrez D; Trollor JN; Valdes-Hernandez MC; van 't Ent D; van Bokhoven H; van der Meer D; van der Wee NJ; Vázquez-Bourgon J; Veltman DJ; Vernooij MW; Villringer A; Vinke LN; Völzke H; Walter H; Wardlaw JM; Weinberger DR; Weiner MW; Wen W; Westlye LT; Westman E; White T; Witte AV; Wolf C; Yang J; Zwiers MP; Ikram MA; Seshadri S; Thompson PM; Satizabal CL; Medland SE; Rentería ME
Corrigendum: NATURE COMMUNICATIONS. 2024;15(1):5784
Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer's disease (vol 13, 4566, 2022)
Poulakis K; Pereira JB; Muehlboeck J-S; Wahlund L-O; Smedby O; Volpe G; Masters CL; Ames D; Niimi Y; Iwatsubo T; Ferreira D; Westman E
Preprint: BIORXIV. 2024;BIORXIV
Altered empathy processing in frontotemporal dementia A task-based fMRI study.
Lindberg O; Li T-Q; Lind C; Vestberg S; Almkvist O; Stiernstedt M; Ericson A; Bogdanovic N; Hansson O; Harper L; Westman E; Graff C; Tsevis T; Mannfolk P; Fischer H; Nilsonne G; Petrovic P; Nyberg L; Wahlund L-O; Santillo AF; Swedish FTD initiative
Review: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 2024;157:105534
Degeneration of the cholinergic system in individuals with subjective cognitive decline: A systematic review
Rodriguez-Hernandez MA; Alemany I; Olofsson JK; Diaz-Galvan P; Nemy M; Westman E; Barroso J; Ferreira D; Cedres N
Corrigendum: ALZHEIMER'S RESEARCH AND THERAPY. 2023;15(1):177
Differential response to donepezil in MRI subtypes of mild cognitive impairment (vol 15, 117, 2023)
Diaz-Galvan P; Lorenzon G; Mohanty R; Martensson G; Cavedo E; Lista S; Vergallo A; Kantarci K; Hampel H; Dubois B; Grothe MJ; Ferreira D; Westman E
Review: AGEING RESEARCH REVIEWS. 2023;90:102042
Vascular cognitive impairment - Past, present, and future challenges
Badji A; Youwakim J; Cooper A; Westman E; Marseglia A
Corrigendum: ALZHEIMER'S RESEARCH AND THERAPY. 2023;15(1):80
Associations between different tau-PET patterns and longitudinal atrophy in the Alzheimer's disease continuum: biological and methodological perspectives from disease heterogeneity (vol 15, 37, 2023)
Mohanty R; Ferreira D; Nordberg A; Westman E
Preprint: RES SQ. 2023;RES SQ
Sex differences in grey matter networks in dementia with Lewy bodies.
Habich A; Oltra J; Schwarz CG; Przybelski SA; Oppedal K; Inguanzo A; Blanc F; Lemstra AW; Hort J; Westman E; Lowe VJ; Boeve BF; Dierks T; Aarsland D; Kantarci K; Ferreira D
Preprint: RES SQ. 2023;RES SQ
Sex differences in brain atrophy in dementia with Lewy bodies.
Oltra J; Habich A; Schwarz CG; Nedelska Z; Przybelski SA; Inguanzo A; Diaz-Galvan P; Lowe VJ; Oppedal K; Blanc F; Lemstra AW; Hort J; Padovani A; Rektorova I; Bonanni L; Massa F; Kramberge MG; Taylor J-P; Snædal J; Walker Z; Antonini A; Segura B; Junque C; Westman E; Boeve BF; Aarsland D; Kantarci K; Ferreira D
Review: MOVEMENT DISORDERS. 2023;38(1):4-15
(Dis-)Connected Dots in Dementia with Lewy Bodies-A Systematic Review of Connectivity Studies
Habich A; Wahlund L-O; Westman E; Dierks T; Ferreira D
Editorial comment: FRONTIERS IN COMPUTATIONAL NEUROSCIENCE. 2023;17:1243092
Clustering and disease subtyping in Neuroscience, toward better methodological adaptations
Poulakis K; Westman E
Review: AGEING RESEARCH REVIEWS. 2022;82:101757
Cerebrovascular damage in subjective cognitive decline: A systematic review and meta-analysis
Pitti H; Diaz-Galvan P; Barroso J; Badji A; Olofsson JK; Westman E; Ferreira D; Cedres N
Review: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2022;10(1):166
The hippocampal sparing subtype of Alzheimer's disease assessed in neuropathology and in vivo tau positron emission tomography: a systematic review
Ferreira D; Mohanty R; Murray ME; Nordberg A; Kantarci K; Westman E
Corrigendum: NATURE. 2022;610(7931):E6
Brain charts for the human lifespan (vol 604, pg 525, 2022)
Bethlehem RAI; Seidlitz J; White SR; Vogel JW; Anderson KM; Adamson C; Adler S; Alexopoulos GS; Anagnostou E; Areces-Gonzalez A; Astle DE; Auyeung B; Ayub M; Bae J; Ball G; Baron-Cohen S; Beare R; Bedford SA; Benegal V; Beyer F; Blangero J; Blesa Cabez M; Boardman JP; Borzage M; Bosch-Bayard JF; Bourke N; Calhoun VD; Chakravarty MM; Chen C; Chertavian C; Chetelat G; Chong YS; Cole JH; Corvin A; Costantino M; Courchesne E; Crivello F; Cropley VL; Crosbie J; Crossley N; Delarue M; Delorme R; Desrivieres S; Devenyi GA; Di Biase MA; Dolan R; Donald KA; Donohoe G; Dunlop K; Edwards AD; Elison JT; Ellis CT; Elman JA; Eyler L; Fair DA; Feczko E; Fletcher PC; Fonagy P; Franz CE; Galan-Garcia L; Gholipour A; Giedd J; Gilmore JH; Glahn DC; Goodyer IM; Grant PE; Groenewold NA; Gunning FM; Gur RE; Gur RC; Hammill CF; Hansson O; Hedden T; Heinz A; Henson RN; Heuer K; Hoare J; Holla B; Holmes AJ; Holt R; Huang H; Im K; Ipser J; Jack CRJ; Jackowski AP; Jia T; Johnson KA; Jones PB; Jones DT; Kahn RS; Karlsson H; Karlsson L; Kawashima R; Kelley EA; Kern S; Kim KW; Kitzbichler MG; Kremen WS; Lalonde F; Landeau B; Lee S; Lerch J; Lewis JD; Li J; Liao W; Liston C; Lombardo MV; Lv J; Lynch C; Mallard TT; Marcelis M; Markello RD; Mathias SR; Mazoyer B; McGuire P; Meaney MJ; Mechelli A; Medic N; Misic B; Morgan SE; Mothersill D; Nigg J; Ong MQW; Ortinau C; Ossenkoppele R; Ouyang M; Palaniyappan L; Paly L; Pan PM; Pantelis C; Park MM; Paus T; Pausova Z; Paz-Linares D; Pichet Binette A; Pierce K; Qian X; Qiu J; Qiu A; Raznahan A; Rittman T; Rodrigue A; Rollins CK; Romero-Garcia R; Ronan L; Rosenberg MD; Rowitch DH; Salum GA; Satterthwaite TD; Schaare HL; Schachar RJ; Schultz AP; Schumann G; Scholl M; Sharp D; Shinohara RT; Skoog I; Smyser CD; Sperling RA; Stein DJ; Stolicyn A; Suckling J; Sullivan G; Taki Y; Thyreau B; Toro R; Traut N; Tsvetanov KA; Turk-Browne NB; Tuulari JJ; Tzourio C; Vachon-Presseau E; Valdes-Sosa MJ; Valdes-Sosa PA; Valk SL; van Amelsvoort T; Vandekar SN; Vasung L; Victoria LW; Villeneuve S; Villringer A; Vertes PE; Wagstyl K; Wang YS; Warfield SK; Warrier V; Westman E; Westwater ML; Whalley HC; Witte AV; Yang N; Yeo B; Yun H; Zalesky A; Zar HJ; Zettergren A; Zhou JH; Ziauddeen H; Zugman A; Zuo XN; Bullmore ET; Alexander-Bloch AF
Letter: JOURNAL OF INTERNAL MEDICINE. 2021;290(2):473-476
Neurofilament light chain as a marker for cortical atrophy in multiple sclerosis without radiological signs of disease activity
Ineichen BV; Moridi T; Ewing E; Ouellette R; Manouchehrinia A; Stawiarz L; Ferreira D; Muehlboeck SJ; Kuhle J; Westman E; Leppert D; Hillert J; Olsson T; Kockum I; Piehl F; Granberg T
Review: BRAIN SCIENCES. 2021;11(6):764
The Use of Magnetic Resonance Imaging Techniques in Assessing the Effects of Alcohol Consumption and Heavy Drinking on the Adolescent Brain: A Scoping Review Protocol
Hornsby N; Seedat S; Westman E; Wahlund L-O; Siegfried N; Erasmus-Claassen L-A; Myers B
Review: NEUROLOGY. 2020;94(10):436-448
Biological subtypes of Alzheimer disease A systematic review and meta-analysis
Ferreira D; Nordberg A; Westman E
Corrigendum: NATURE NEUROSCIENCE. 2020;23(2):295
Common brain disorders are associated with heritable patterns of apparent aging of the brain (vol 22, pg 1617, 2019)
Kaufmann T; van der Meer D; Nhat TD; Schwarz E; Lund MJ; Agartz I; Alnaes D; Barch DM; Baur-Streubel R; Bertolino A; Bettella F; Beyer MK; Boen E; Borgwardt S; Brandt CL; Buitelaar J; Celius EG; Cervenka S; Conzelmann A; Cordova-Palomera A; Dale AM; de Quervain DJF; Di Carlo P; Djurovic S; Dorum ES; Eisenacher S; Elvsashagen T; Espeseth T; Fatouros-Bergman H; Flyckt L; Franke B; Frei O; Haatveit B; Haberg AK; Harbo HF; Hartman CA; Heslenfeld D; Hoekstra PJ; Hogestol EA; Jernigan TL; Jonassen R; Jonsson EG; Kirsch P; Kloszewska I; Kolskar KK; Landro NI; Le Hellard S; Lesch K-P; Lovestone S; Lundervold A; Lundervold AJ; Maglanoc LA; Malt UF; Mecocci P; Melle I; Meyer-Lindenberg A; Moberget T; Norbom LB; Nordvik JE; Nyberg L; Oosterlaan J; Papalino M; Papassotiropoulos A; Pauli P; Pergola G; Persson K; Richard G; Rokicki J; Sanders A-M; Selbaek G; Shadrin AA; Smeland OB; Soininen H; Sowa P; Steen VM; Tsolaki M; Ulrichsen KM; Vellas B; Wang L; Westman E; Ziegler GC; Zink M; Andreassen OA; Westlye LT
Letter: JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY. 2020;91(1):109-110
CSF tau proteins correlate with an atypical clinical presentation in dementia with Lewy bodies
Di Censo R; Abdelnour C; Blanc F; Bousiges O; Lemstra AW; van Steenoven I; Onofrj M; Aarsland D; Bonanni L
Editorial comment: NEURODEGENERATIVE DISEASE MANAGEMENT. 2019;9(5):247-250
European DLB consortium: diagnostic and prognostic biomarkers in dementia with Lewy bodies, a multicenter international initiative
Oppedal K; Borda MG; Ferreira D; Westman E; Aarsland D
Review: ALZHEIMER'S AND DEMENTIA. 2019;15(6):828-839
The MOPEAD project: Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community
Rodriguez-Gomez O; Rodrigo A; Iradier F; Santos-Santos MA; Hundemer H; Ciudin A; Sannemann L; Zwan M; Glaysher B; Wimo A; Bonn J; Johansson G; Rodriguez I; Alegret M; Gove D; Pino S; Trigueros P; Kivipelto M; Mathews B; Ciudad A; Ferreira D; Bintener C; Gurruchaga M; Westman E; Belger M; Valero S; Maguire P; Krivec D; Kramberger M; Simo R; Garro IP; Visser PJ; Dumas A; Georges J; Jessen F; Winblad B; Shering C; Stewart N; Campo L; Boada M
Editorial comment: AGING. 2018;10(11):3058-3060
The heterogeneity within Alzheimer's disease
Ferreira D; Wahlund L-O; Westman E
Review: QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;61(4):372-385
Clinical utility and research frontiers of neuroimaging in movement disorders
Nobili F; Westman E; Kogan RV; Pereira JB; Massa F; Grazzini M; Meles SK; Leenders KL
Review: INSIGHTS INTO IMAGING. 2017;8(1):79-90
Imaging biomarkers of dementia: recommended visual rating scales with teaching cases
Wahlund L-O; Westman E; van Westen D; Wallin A; Shams S; Cavallin L; Larsson E-M
Published conference paper: NEURODEGENERATIVE DISEASES. 2016;16(1-2):77-86
Measuring Global Brain Atrophy with the Brain Volume/Cerebrospinal Fluid Index: Normative Values, Cut-Offs and Clinical Associations
Orellana C; Ferreira D; Muehlboeck J-S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Simmons A; Wahlund L-O; Westman E
Review: JOURNAL OF ALZHEIMER'S DISEASE. 2014;41(3):685-708
Multivariate Data Analysis and Machine Learning in Alzheimer's Disease with a Focus on Structural Magnetic Resonance Imaging
Falahati F; Westman E; Simmons A
Review: FRONTIERS IN AGING NEUROSCIENCE. 2014;6:287
Improving CSF biomarkers' performance for predicting progression from Mild Cognitive Impairment to Alzheimer's disease by considering different confounding factors: a meta-analysis
Ferreira D; Rivero-Santana A; Perestelo-Perez L; Westman E; Wahlund L-O; Sarria A; Serrano-Aguilar P
Review: FRONTIERS IN AGING NEUROSCIENCE. 2014;6:47
Meta-review of CSF core biomarkers in Alzheimer's disease: the state-of-the-art after the new revised diagnostic criteria
Ferreira D; Perestelo-Perez L; Westman E; Wahlund L-O; Sarria A; Serrano-Aguilar P
Review: JOURNAL OF ALZHEIMER'S DISEASE. 2013;38(3):515-531
Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study
Kiddle SJ; Sattlecker M; Proitsi P; Simmons A; Westman E; Bazenet C; Nelson SK; Williams S; Hodges A; Johnston C; Soininen H; Kloszewska I; Mecocci P; Tsolaki M; Vellas B; Newhouse S; Lovestone S; Dobson RJB
Review: LAKARTIDNINGEN. 2013;110(47):2116-2118
[Structural brain imaging may improve diagnostics in dementia].
Wahlund L-O; Westman E; Van Westen D; Wallin A; Cavallin L; Larsson E-M
Review: LANCET NEUROLOGY. 2012;11(8):697-707
Cognitive impairment in patients with Parkinson's disease: diagnosis, biomarkers, and treatment
Svenningsson P; Westman E; Ballard C; Aarsland D
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2009;1180:47-55
MRI Measures of Alzheimer's Disease and the AddNeuroMed Study
Simmons A; Westman E; Muehlboeck S; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Wahlund L-O; Soininen H; Lovestone S; Evans A; Spenger C
Thesis / dissertation: 2009
Magnetic resonance studies in Alzheimer's disease
Westman, Eric
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Grants

Mental and cognitive health in relation to functional ability and somatic health in the elderly. The influence of age, sex, birth cohort, genetic, psychological, social and neurobiological factors
Swedish Research Council
1 January 2023 - 31 December 2026
Park-MOVE: Moving towards personalized rehabilitation for Parkinson’s disease informed by diversity, exercise responders and brain activity during motion.
Swedish Research Council
1 January 2023 - 31 December 2026
Guiding dementia research towards precision medicine - a brain imaging study to unravel the heterogeneity in Alzheimer´s disease
Swedish Research Council
1 December 2021 - 30 November 2025
Investigating the potential of combination therapies targeting the cholinergic system in Alzheimer´s disease
Swedish Research Council
1 January 2021 - 31 December 2023
Mental and cognitive health in the elderly. Relation to age, sex, birth cohort, functional ability, somatic health, genetic, psychological, social and neurobiological factors
Swedish Research Council
1 January 2020 - 31 December 2022
The baby-boomers and the new ageing. Birth cohorts born 1901-1944 are followed from age 70 to 75 regarding how physical, mental, cognitive, social, and functional ability changes with age
Swedish Research Council for Health Working Life and Welfare
1 January 2019 - 31 December 2021
Dementia Prevention Platform for Theme Aging: from accurate disease models and prognostic tools to effective interventions
Swedish Research Council
1 December 2017 - 31 December 2022
Improving early identification of dementia risk by means of multimodal neuroimaging
Western Norway Regional Health Authority
1 January 2017 - 31 December 2021
Brain networks and disease patterns in neurodegenerative disorders: A brain imaging study to provide a platform for successful clinical trials
Swedish Research Council
1 January 2017 - 31 December 2020
Clinical complexity at the memory clinics – is it possible to identify prodromal dementia with only clinical parameters?
Swedish Research Council
1 January 2017 - 31 December 2019
The revival of the cholinergic system in Alzheimer´s disease - Cognitive impairment, cognitive restoration and early diagnosis in Alzheimer´s disease
Swedish Research Council
1 January 2017 - 31 December 2020
Mental and cognitive health in relation to functional ability and somatic health in the elderly. The influence of age, sex, birth cohort, genetic, psychological, social and neurobiological factors.
Swedish Research Council
1 January 2016 - 31 December 2019
An integrated research project between the Stockholm memory clinics to increase knowledge about prognostic information, cognitive and physiological mechanisms, and diagnostic accuracy
Swedish Research Council for Health Working Life and Welfare
1 January 2016 - 31 December 2017
New biomarkers in early diagnosis and treatment of AD
Swedish Foundation for Strategic Research
1 January 2015 - 31 December 2019
Depression & cognition in the elderly: a neuroimaging perspective
Western Norway Regional Health Authority
1 January 2013 - 31 December 2014

Employments

Professor, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2020-

Degrees and Education

Docent, Karolinska Institutet, 2014
Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2009
MSc in Biomedical Engineering, Pattern recognition analysis of spectra obtained by in vivo MRS and HR MAS of brains in transgenic mouse models for Alzheimer’s disease, Royal Institute of Technology, 2004

Leadership and responsibility assignments

Responsible for a section, Division of Clinical Geriatrics, NVS, Karolinska Institute, https://ki.se/en/nvs/westman-neuroimaging-group, 2012-

Supervisor

Moa Peter, Neural and behavioral plasticity in olfactory sensory deprivation, https://www.dissertations.se/dissertation/9143d73b8f/, 2015

About me

Research

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Employments

Degrees and Education

Leadership and responsibility assignments

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