Gerd Faxén-Irving

Publications
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Public outreach and news

Articles

Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39(11):gfae077-1875
The safety of a low-protein diet in older adults with advanced chronic kidney disease
Windahl K; Chesnaye NC; Irving GF; Stenvinkel P; Almquist T; Liden MK; Drechsler C; Szymczak M; Krajewska M; de Rooij E; Torino C; Porto G; Caskey FJ; Wanner C; Jager KJ; Dekker FW; Evans M
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2024;120(3):719-726
Plant-based diet in hyperkalemic chronic kidney disease patients receiving sodium zirconium cyclosilicate: a feasibility clinical trial
Avesani CM; Heimburger O; Rubin C; Sallstrom T; Faxen-Irving G; Lindholm B; Stenvinkel P
Article: ALZHEIMERS RESEARCH & THERAPY. 2024;16(1):147
Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer's disease: Multimodal Preventive Trial for Alzheimer's Disease (MIND-AD_mini)
Levak N; Lehtisalo J; Thunborg C; Westman E; Andersen P; Andrieu S; Broersen LM; Coley N; Hartmann T; Irving GF; Mangialasche F; Ngandu T; Pantel J; Rosenberg A; Sindi S; Soininen H; Solomon A; Wang R; Kivipelto M
Article: CLINICAL NUTRITION. 2024;43(6):1599-1626
ESPEN guideline on nutrition and hydration in dementia- Update 2024
Volkert D; Beck AM; Faxen-Irving G; Fruehwald T; Hooper L; Keller H; Porter J; Rothenberg E; Suominen M; Wirth R; Chourdakis M
Article: ALZHEIMERS RESEARCH & THERAPY. 2024;16(1):118
Integrating a multimodal lifestyle intervention with medical food in prodromal Alzheimer's disease: the MIND-AD_mini randomized controlled trial
Thunborg C; Wang R; Rosenberg A; Sindi S; Andersen P; Andrieu S; Broersen LM; Coley N; Couderc C; Duval CZ; Faxen-Irving G; Hagman G; Hallikainen M; Hakansson K; Kekkonen E; Lehtisalo J; Levak N; Mangialasche F; Pantel J; Rydstrom A; Stigsdotter-Neely A; Wimo A; Ngandu T; Soininen H; Hartmann T; Solomon A; Kivipelto M
Article: LAKARTIDNINGEN. 2023;120:23062
Träning och protein för funktion och självtillit.
Boström A-M; Faxén-Irving G; Franzén E; Grönstedt H; Seiger Å; Vikström S; Wimo A; Cederholm T
Article: JOURNAL OF INTERNAL MEDICINE. 2023;294(3):358-369
Urinary phosphate is associated with cardiovascular disease incidence
Donat-Vargas C; Guallar-Castillon P; Nystrom J; Larsson SC; Kippler M; Vahter M; Faxen-Irving G; Michaelsson K; Wolk A; Stenvinkel P; Akesson A
Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2022;19(10):5801
The Relation between Masticatory Function and Nutrition in Older Individuals, Dependent on Supportive Care for Daily Living
Stjernfeldt PE; Irving GF; Wardh I; Lundqvist R; Lantto A
Article: JOURNAL OF RENAL NUTRITION. 2022;32(2):161-169
Patient-Reported Measures and Lifestyle Are Associated With Deterioration in Nutritional Status in CKD Stage 4-5: The EQUAL Cohort Study
Windahl K; Irving GF; Almquist T; Liden MK; Stenvinkel P; Chesnaye NC; Drechsler C; Szymczak M; Krajewska M; Fu EL; Torino C; Porto G; Roderick P; Caskey FJ; Wanner C; Dekker FW; Jager KJ; Evans M
Article: JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE. 2022;9(1):30-39
Multimodal Preventive Trial for Alzheimer's Disease: MIND-ADmini Pilot Trial Study Design and Progress
Sindi S; Thunborg C; Rosenberg A; Andersen P; Andrieu S; Broersen LM; Coley N; Couderc C; Duval CZ; Faxen-Irving G; Hagman G; Hallikainen M; Hakansson K; Lehtisalo J; Levak N; Mangialasche F; Pantel J; Kekkonen E; Rydstrom A; Stigsdotter-Neely A; Wimo A; Ngandu T; Soininen H; Hartmann T; Solomon A; Kivipelto M
Article: JOURNAL OF MULTIDISCIPLINARY HEALTHCARE. 2022;15:2615-2622
Factors Associated with Health-Related Quality of Life in Older Persons Residing in Nursing Homes
Bostrom A-M; Cederholm T; Faxen-Irving G; Franzen E; Gronstedt H; Seiger A; Vikstrom S; Wimo A
Article: JOURNAL OF ALZHEIMERS DISEASE. 2021;83(3):1291-1301
Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease: A Randomized Controlled Trial-The OmegAD Study
Tofiq A; Zetterberg H; Blennow K; Basun H; Cederholm T; Eriksdotter M; Faxen-Irving G; Hjorth E; Jerneren F; Schultzberg M; Wahlund L-O; Palmblad J; Freund-Levi Y
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2021;22(9):1939-1945.e3
Response and Adherence of Nursing Home Residents to a Nutrition/ Exercise Intervention
Karlsson ES; Gronstedt HK; Faxen-Irving G; Franzen E; Luiking YC; Seiger A; Vikstrom S; Wimo A; Cederholm TE; Bostrom A-M
Article: GERODONTOLOGY. 2021;38(2):199-208
Masticatory ability in older individuals: A qualitative interview study
Elgestad Stjernfeldt P; Faxen-Irving G; Wardh I
Article: BMC GERIATRICS. 2021;21(1):109
Experiences of supporting older persons in completion of an exercise and nutrition intervention: an interview study with nursing home staff
Vikstrom S; Gronstedt HK; Cederholm T; Franzen E; Faxen-Irving G; Seiger A; Bostrom A-M
Article: THE JOURNAL OF FRAILTY & AGING. 2021;10(1):17-21
DO MALNUTRITION, SARCOPENIA AND FRAILTY OVERLAP IN NURSING-HOME RESIDENTS?
Faxen-Irving G; Luiking Y; Gronstedt H; Franzen E; Seiger A; Vikstrom S; Wimo A; Bostrom A-M; Cederholm T
Article: BMC GERIATRICS. 2020;20(1):324
A health concept with a social potential: an interview study with nursing home residents
Vikstrom S; Gronstedt HK; Cederholm T; Franzen E; Seiger A; Faxen-Irving G; Bostrom A-M
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2020;21(9):1229-1237
Effect of Sit-to-Stand Exercises Combined With Protein-Rich Oral Supplementation in Older Persons: The Older Person's Exercise and Nutrition Study
Gronstedt H; Vikstrom S; Cederholm T; Franzen E; Luiking YC; Seiger A; Wimo A; Faxen-Irving G; Bostrom A-M
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;69(1):189-197
Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study
Jerneren F; Cederholm T; Refsum H; Smith AD; Turner C; Palmblad J; Eriksdotter M; Hjorth E; Faxen-Irving G; Wahlund L-O; Schultzberg M; Basun H; Freund-Levi Y
Article: NUTRIENTS. 2018;10(9):1297
An Active Lifestyle Reinforces the Effect of a Healthy Diet on Cognitive Function: A Population-Based Longitudinal Study
Shakersain B; Rizzuto D; Wang H-X; Faxen-Irving G; Prinelli F; Fratiglioni L; Xu W
Article: BMC GERIATRICS. 2018;18(1):138
A study protocol of Older Person's Exercise and Nutrition Study (OPEN) - a sit-to-stand activity combined with oral protein supplement - effects on physical function and independence: a cluster randomized clinical trial
Gronstedt H; Vikstrom S; Cederholm T; Franzen E; Seiger A; Wimo A; Faxen-Irving G; Bostrom A-M
Article: JOURNAL OF RENAL NUTRITION. 2018;28(3):165-174
Prevalence and Risk of Protein-Energy Wasting Assessed by Subjective Global Assessment in Older Adults With Advanced Chronic Kidney Disease: Results From the EQUAL Study
Windahl K; Irving GF; Almquist T; Liden MK; van de Luijtgaarden M; Chesnaye NC; Voskamp P; Stenvinkel P; Klinger M; Szymczak M; Torino C; Postorini M; Drechsler C; Caskey FJ; Wanner C; Dekker FW; Jager KJ; Evans M
Article: NUTRIENTS. 2018;10(2):229
The Nordic Prudent Diet Reduces Risk of Cognitive Decline in the Swedish Older Adults: A Population-Based Cohort Study
Shakersain B; Rizzuto D; Larsson SC; Faxen-Irving G; Fratiglioni L; Xu W-L
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;61(2):515-519
Does Fatty Acid Composition in Subcutaneous Adipose Tissue Differ between Patients with Alzheimer's Disease and Cohabiting Proxies?
Faxen-Irving G; Falahati F; Basun H; Eriksdotter M; Vedin I; Wahlund L-O; Schultzberg M; Hjorth E; Palmblad J; Cederholm T; Freund-Levi Y
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2017;106(4):1157-1165
DHA-rich n-3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study
Karimi M; Vedin I; Levi YF; Basun H; Irving GF; Eriksdotter M; Wahlund L-O; Schultzberg M; Hjorth E; Cederholm T; Palmblad J
Article: BMC NEPHROLOGY. 2016;17(1):89
A practical approach to low protein diets in Sweden-45 years of clinical use
Eyre S; Faxen-Irving G; Attman P-O; Evans M; Windahl K; Wegener S; Andersen C; Nykvist-Raanaes K; Einemo S; Carrero J-J
Article: CLINICAL NUTRITION. 2016;35(3):692-698
Individually prescribed diet is fundamental to optimize nutritional treatment in geriatric patients
Hedman S; Nydahl M; Faxen-Irving G
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2016;17(3):275.e5-275.11
Effects on Weight, Blood Lipids, Serum Fatty Acid Profile and Coagulation by an Energy-Dense Formula to Older Care Residents: A Randomized Controlled Crossover Trial
Tylner S; Cederholm T; Faxen-Irving G
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2016;70(3):320-325
Nutritional status and survival among old adults: an 11-year population-based longitudinal study
Shakersain B; Santoni G; Faxen-Irving G; Rizzuto D; Fratiglioni L; Xu W
Article: ALZHEIMERS & DEMENTIA. 2016;12(2):100-109
Prudent diet may attenuate the adverse effects of Western diet on cognitive decline
Shakersain B; Santoni G; Larsson SC; Faxen-Irving G; Fastbom J; Fratiglioni L; Xu W
Article: FOOD & NUTRITION RESEARCH. 2016;60:30456
Nutritional assessment and post-procedural complications in older stroke patients after insertion of percutaneous endoscopic gastrostomy - a retrospective study
Hede GW; Faxen-Irving G; Olin AO; Ebbeskog B; Crisby M
Article: CLINICAL NUTRITION. 2015;34(6):1052-1073
ESPEN guidelines on nutrition in dementia
Volkert D; Chourdakis M; Faxen-Irving G; Fruhwald T; Landi F; Suominen MH; Vandewoude M; Wirth R; Schneider SM
Article: JOURNAL OF ALZHEIMERS DISEASE. 2015;48(3):805-812
Plasma Fatty Acid Profiles in Relation to Cognition and Gender in Alzheimer's Disease Patients During Oral Omega-3 Fatty Acid Supplementation: The OmegAD Study
Eriksdotter M; Vedin I; Falahati F; Freund-Levi Y; Hjorth E; Faxen-Irving G; Wahlund L-O; Schultzberg M; Basun H; Cederholm T; Palmblad J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2014;42(3):823-831
Effects of Supplementation with Omega-3 Fatty Acids on Oxidative Stress and Inflammation in Patients with Alzheimer's Disease: The OmegAD Study
Freund-Levi Y; Vedin I; Hjorth E; Basun H; Irving GF; Schultzberg M; Eriksdotter M; Palmblad J; Vessby B; Wahlund L-O; Cederholm T; Basu S
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA. 2014;4(1):65-75
Body Mass Index in Different Dementia Disorders: Results from the Swedish Dementia Quality Registry (SveDem).
Faxén-Irving G; Fereshtehnejad S-M; Falahati F; Cedergren L; Göranzon H; Wallman K; García-Ptacek S; Eriksdotter M; Religa D
Article: JOURNAL OF INTERNAL MEDICINE. 2014;275(4):428-436
Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study
Levi YF; Vedin I; Cederholm T; Basun H; Irving GF; Eriksdotter M; Hjorth E; Schultzberg M; Vessby B; Wahlund L-O; Salem NJ; Palmblad J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2013;36(1):1-6
Effects on Transthyretin in Plasma and Cerebrospinal Fluid by DHA-Rich n-3 Fatty Acid Supplementation in Patients with Alzheimer's Disease: The OmegAD Study
Faxen-Irving G; Freund-Levi Y; Eriksdotter-Jonhagen M; Basun H; Hjorth E; Palmblad J; Vedin I; Cederholm T; Wahlund L-O
Article: JOURNAL OF ALZHEIMERS DISEASE. 2013;35(4):697-713
Omega-3 Fatty Acids Enhance Phagocytosis of Alzheimer's Disease-Related Amyloid-β₄₂ by Human Microglia and Decrease Inflammatory Markers
Hjorth E; Zhu M; Toro VC; Vedin I; Palmblad J; Cederholm T; Freund-Levi Y; Faxen-Irving G; Wahlund L-O; Basun H; Eriksdotter M; Schultzberg M
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2012;27(6):2430-2434
Physical activity and energy expenditure in haemodialysis patients: an international survey
Avesani CM; Trolonge S; Deleaval P; Baria F; Mafra D; Faxen-Irving G; Chauveau P; Teta D; Kamimura MA; Cuppari L; Chan M; Heimbuerger O; Fouque D
Article: PLOS ONE. 2012;7(4):e35425
Effects of DHA- Rich n-3 Fatty Acid Supplementation on Gene Expression in Blood Mononuclear Leukocytes: The OmegAD Study
Vedin I; Cederholm T; Freund-Levi Y; Basun H; Garlind A; Irving GF; Eriksdotter-Jonhagen M; Wahlund L-O; Dahlman I; Palmblad J
Article: CLINICAL NUTRITION. 2011;30(2):202-208
Energy dense oleic acid rich formula to newly admitted geriatric patients - Feasibility and effects on energy intake
Faxen-Irving G; Cederholm T
Article: FOOD & NUTRITION RESEARCH. 2011;55:6037
Indications for percutaneous endoscopic gastrostomy and survival in old adults
Malmgren A; Hede GW; Karlstrom B; Cederholm T; Lundquist P; Wiren M; Faxen-Irving G
Article: AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS. 2010;25(6):521-526
To Be a Good Food Provider: An Exploratory Study Among Spouses of Persons With Alzheimer's Disease
Fjellstrom C; Starkenberg A; Wesslen A; Licentiate MS; Backstrom A-CT; Faxen-Irving G
Article: SEMINARS IN DIALYSIS. 2010;23(4):383-388
To Eat or Not to Eat: Dietary Fat in Uremia Is the Question
Axelsson TG; Irving GF; Axelsson J
Article: JOURNAL OF LIPID RESEARCH. 2010;51(5):1179-1185
Reduced prostaglandin F_2α release from blood mononuclear leukocytes after oral supplementation of ω3 fatty acids: the OmegAD study
Vedin I; Cederholm T; Freund-Levi Y; Basun H; Hjorth E; Irving GF; Eriksdotter-Jonhagen M; Schultzberg M; Wahlund L-O; Palmblad J
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2009;57(1):11-17
Omega-3 Fatty Acid Supplementation Effects on Weight and Appetite in Patients with Alzheimer's Disease: The Omega-3 Alzheimer's Disease Study
Irving GF; Freund-Levi Y; Eriksdotter-Joenhagen M; Basun H; Brismar K; Hjorth E; Palmblad J; Vessby B; Vedin I; Wahlund L-O; Cederholm T
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2009;27(5):481-490
Effects of Omega-3 Fatty Acids on Inflammatory Markers in Cerebrospinal Fluid and Plasma in Alzheimer's Disease: The OmegAD Study
Freund-Levi Y; Hjorth E; Lindberg C; Cederholm T; Faxen-Irving G; Vedin I; Palmblad J; Wahlund L-O; Schultzberg M; Basun H; Jonhagen ME
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2008;87(6):1616-1622
Effects of docosahexaenoic acid-rich n-3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study
Vedin I; Cederholm T; Levi YF; Basun H; Garlind A; Irving GF; Joenhagen ME; Vessby B; Wahlund L-O; Palmblad J
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2008;23(2):161-169
Omega-3 supplementation in mild to moderate Alzheimer's disease:: effects on neuropsychiatric symptoms
Freund-Levi Y; Basun H; Cederholm T; Faxen-Irving G; Garlind A; Grut M; Vedin I; Palmblad J; Wahlund L-O; Eriksdotter-Jonhagen M
Article: ARCHIVES OF NEUROLOGY. 2006;63(10):1402-1408
ω-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease:: OmegAD study -: A randomized double-blind trial
Freund-Levi Y; Eriksdotter-Jonhagen M; Cederholm T; Basun H; Faxen-Irving G; Garlind A; Vedin I; Vessby B; Wahlund L-O; Palmblad J
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2005;59(8):947-954
Nutrition education for care staff and possible effects on nutritional status in residents of sheltered accomodation
Faxén-Irving G; Andrén-Olsson B; Geijerstam A; Basun H; Cederholm T
Article: AGE AND AGEING. 2005;34(2):136-141
Nutritional and cognitive relationships and long-term mortality in patients with various dementia disorders
Faxén-Irving G; Basun H; Cederholm T
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2002;56(3):221-227
The effect of nutritional intervention in elderly subjects residing in group-living for the demented.
Faxén-Irving G; Andrén-Olsson B; af Geijerstam A; Basun H; Cederholm T
Article: GERONTOLOGY. 1999;45(4):187-194
Nutritional and cognitive status in elderly subjects living in service flats, and the effect of nutrition education on personnel.
Irving GF; Olsson BA; Cederholm T
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Letter: LAKARTIDNINGEN. 2024;121:23167
Proteinreducerad kost behöver återupptäckas vid njursvikt.
Eyre S; Ola Attman P; Faxén Irving G; Lindholm B
Review: JOURNAL OF FUNCTIONAL FOODS. 2018;40:715-721
Curcumin - A promising nutritional strategy for chronic kidney disease patients
Alvarenga LDA; Leal VDO; Borges NA; de Aguiar AS; Faxen-Irving G; Stenvinkel P; Lindholm B; Mafra D
Review: SYSTEMATIC REVIEWS. 2017;6(1):20
Methods for objectively assessing clinical masticatory performance: protocol for a systematic review
Stjernfeldt PE; Wardh I; Trulsson M; Irving GF; Bostrom A-M
Letter: LAKARTIDNINGEN. 2014;111(51-52):2299-2300
[SBU report "misses" persuasive evidence. Dietary supplements extends the life of malnourished elderly].
Cederholm T; Bosaeus I; Brummer R; Ellegård L; Irving GF; Larsson J; Thorell A; Rothenberg E
Review: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2014;68(11):1204-1209
Body mass index in dementia
Garcia-Ptacek S; Faxen-Irving G; Cermakova P; Eriksdotter M; Religa D
Thesis / dissertation: 2004
Nutritional status and cognitive function in frail elderly subjects
Faxén Irving, Gerd

Employments

Affiliated to Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2022-2025

Degrees and Education

Docent, Karolinska Institutet, 2016
Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2004

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