Per Julin

About me
Publications
CV
Public outreach and news

About me

I'm MD, PhD, Specialist in Rehabilitation Medicine and currently senior
consultant at the ME/CFS policlinic at Neurological Rehabilitation Clinic at
Stora Sköndal Foundation.

Research

My research area is the neurobiology of cognitive disorders from a broad
perspective. My main interest is in structural and functional neuroimaging
using MRI or PET/SPECT in cognitive disorders, in relation to diagnosis
and to symptoms but also to effects of treatment/rehabilitation and in
relation to other biomarkers. Currently my focus is on myalgic
encephalomyelitis/chronic fatigue syndrome (ME/CFS).

Articles

Article: OXFORD OPEN IMMUNOLOGY. 2023;4(1):iqad003
Achieving symptom relief in patients with myalgic encephalomyelitis by targeting the neuro-immune interface and optimizing disease tolerance.
Rodriguez L; Pou C; Lakshmikanth T; Zhang J; Mugabo CH; Wang J; Mikes J; Olin A; Chen Y; Rorbach J; Juto J-E; Li TQ; Julin P; Brodin P
Article: TOMOGRAPHY. 2021;7(4):675-687
Limbic Perfusion Is Reduced in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Li X; Julin P; Li T-Q
Article: LAKARTIDNINGEN. 2020;117:20008
Inflammation, långvarig trötthet och värk – uppdatering av kunskapsläget.
Gunnarsson L-G; Julin P; Norén T
Article: BRAIN, BEHAVIOR, & IMMUNITY - HEALTH. 2020;7:100107
Autoantibodies to beta-adrenergic and muscarinic cholinergic receptors in Myalgic Encephalomyelitis (ME) patients - A validation study in plasma and cerebrospinal fluid from two Swedish cohorts
Bynke A; Julin P; Gottfries C-G; Heidecke H; Scheibenbogen C; Bergquist J
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1946
Antibodies to Human Herpesviruses in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
Blomberg J; Rizwan M; Bohlin-Wiener A; Elfaitouri A; Julin P; Zachrisson O; Rosen A; Gottfries C-G
Article: FRONTIERS IN NEUROLOGY. 2017;8:496
Fatigue and cognitive Fatigability in Mild Traumatic Brain injury are correlated with altered neural activity during Vigilance Test Performance
Moller MC; Nordin LE; Bartfai A; Julin P; Li T-Q
Article: SCIENTIFIC REPORTS. 2016;6:21183
Post mTBI fatigue is associated with abnormal brain functional connectivity
Nordin LE; Moller MC; Julin P; Bartfai A; Hashim F; Li T-Q
Article: BMC NEUROLOGY. 2015;15:52
Cortical activation changes and improved motor function in stroke patients after focal spasticity therapy-an interventional study applying repeated fMRI
Bergfeldt U; Jonsson T; Bergfeldt L; Julin P
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40(4):580-593
Low background and high contrast PET imaging of amyloid-β with [¹¹C]AZD2995 and [¹¹C]AZD2184 in Alzheimer's disease patients
Forsberg A; Jureus A; Cselenyi Z; Eriksdotter M; Freund-Levi Y; Jeppsson F; Swahn B-M; Sandell J; Julin P; Schou M; Andersson J; Johnstrom P; Varnas K; Halldin C; Farde L; Svensson S
Article: NEUROIMAGE. 2013;68:75-82
Cortical responses to amphetamine exposure studied by pCASL MRI and pharmacokinetic/pharmacodynamic dose modeling
Nordin LE; Li T-Q; Brogren J; Johansson P; Sjogren N; Hannesdottir K; Bjork C; Segerdahl M; Wang DJJ; Julin P
Article: EJNMMI RESEARCH. 2012;2:15
Kinetic analysis and test-retest variability of the radioligand [¹¹C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects
Jucaite A; Cselenyi Z; Arvidsson A; Ahlberg G; Julin P; Varnas K; Stenkrona P; Andersson J; Halldin C; Farde L
Article: JOURNAL OF NUCLEAR MEDICINE. 2012;53(3):415-424
Clinical Validation of ¹⁸F-AZD4694, an Amyloid-β-Specific PET Radioligand
Cselenyi Z; Jonhagen ME; Forsberg A; Halldin C; Julin P; Schou M; Johnstrom P; Varnas K; Svensson S; Farde L
Article: ALZHEIMERS & DEMENTIA. 2012;8(1):51-59
Direct comparison of fluorodeoxyglucose positron emission tomography and arterial spin labeling magnetic resonance imaging in Alzheimer's disease.
Musiek ES; Chen Y; Korczykowski M; Saboury B; Martinez PM; Reddin JS; Alavi A; Kimberg DY; Wolk DA; Julin P; Newberg AB; Arnold SE; Detre JA
Article: NEUROLOGY. 2011;77(22):1977-1985
Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease.
Chen Y; Wolk DA; Reddin JS; Korczykowski M; Martinez PM; Musiek ES; Newberg AB; Julin P; Arnold SE; Greenberg JH; Detre JA
Article: ARCHIVES OF NEUROLOGY. 2010;67(11):1370-1378
Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative.
Carmichael O; Schwarz C; Drucker D; Fletcher E; Harvey D; Beckett L; Jack CR; Weiner M; DeCarli C; Alzheimer's Disease Neuroimaging Initiative
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36(11):1859-1863
Detection of amyloid in Alzheimer's disease with positron emission tomography using [¹¹C]AZD2184
Nyberg S; Jonhagen ME; Cselenyi Z; Halldin C; Julin P; Olsson H; Freund-Levi Y; Andersson J; Varnas K; Svensson S; Farde L
Article: NEUROSCIENCE LETTERS. 2009;462(1):89-93
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease
Solomon A; Leoni V; Kivipelto M; Besga A; Oksengard AR; Julin P; Svensson L; Wahlund L-O; Andreasen N; Winblad B; Soininen H; Bjorkhem I
Article: BMC MEDICAL IMAGING. 2009;9:15
Parallel imaging: is GRAPPA a useful acquisition tool for MR imaging intended for volumetric brain analysis?
Lindholm TL; Botes L; Engman E-L; Frank A; Jonsson T; Svensson L; Julin P
Article: JOURNAL OF REHABILITATION MEDICINE. 2009;41(4):279-281
SHORT FORM 36 ASSESSED HEALTH-RELATED QUALITY OF LIFE AFTER FOCAL SPASTICITY THERAPY
Bergfeldt U; Skoeld C; Julin P
Article: ACTA RADIOLOGICA. 2008;49(10):1154-1161
Voxel-Based Correlation between Coregistered Single-Photon Emission Computed Tomography and Dynamic Susceptibility Contrast Magnetic Resonance Imaging in Subjects with Suspected Alzheimer Disease
Cavallin L; Axelsson R; Wahlund LO; Oksengard AR; Svensson L; Juhlin P; Wiberg MK; Frank A
Article: CLINICAL NEUROSCIENCE RESEARCH. 2007;6(6):367-373
Identifying functional imaging markers of mild cognitive impairment in early Alzheimer's and Parkinson's disease using multivariate analysis
Huang C; Mattis P; Julin P
Article: NEUROBIOLOGY OF AGING. 2007;28(7):1062-1069
Imaging markers of mild cognitive impairment: Multivariate analysis of CBFSPECT
Huang C; Eidelberg D; Habeek C; Moeller J; Svensson L; Tarabula T; Julin P
Article: ACTA RADIOLOGICA. 2006;47(9):977-985
Can dynamic susceptibility contrast magnetic resonance imaging replace single-photon emission computed tomography in the diagnosis of patients with Alzheimer's disease?: A pilot study
Cavallin L; Danielsson R; Oeksengard AR; Wahlund LO; Julin P; Frank A; Engman EL; Svensson L; Wiberg MK
Article: JOURNAL OF REHABILITATION MEDICINE. 2006;38(5):302-308
Whole-body vibration training compared with resistance training: Effect on spasticity, muscle strength and motor performance in adults with cerebral palsy
Ahlborg L; Andersson C; Julin P
Article: JOURNAL OF REHABILITATION MEDICINE. 2006;38(3):166-171
Focal spasticity therapy with botulinum toxin: Effects on function, activities of daily living and pain in 100 adult patients
Bergfeldt U; Borg K; Kullander K; Julin P
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2004;19(10):995-1007
Intracranial volume in mild cognitive impairment, Alzheimer's disease and vascular dementia: evidence for brain reserve?
Wolf H; Julin P; Gertz HJ; Winblad B; Wahlund LO
Article: NEUROIMAGE. 2003;19(3):1137-1144
Voxel- and VOI-based analysis of SPECT CBF in relation to clinical and psychological heterogeneity of mild cognitive impairment
Huang CR; Wahlund LO; Almkvist O; Elehu D; Svensson L; Jonsson T; Winblad B; Julin P
Article: BMC NEUROLOGY. 2002;2:9
Cingulate cortex hypoperfusion predicts Alzheimer's disease in mild cognitive impairment
Huang C; Wahlund L-O; Svensson L; Winblad B; Julin P
Article: MEDICAL PHYSICS. 2001;28(8):1660-1668
Evaluation of linear registration algorithms for brain SPECT and the errors due to hypoperfusion lesions
Radau PE; Slomka PJ; Julin P; Svensson L; Wahlund LO
Article: CLINICAL NEUROPHYSIOLOGY. 2000;111(11):1961-1967
Discrimination of Alzheimer's disease and mild cognitive impairment by equivalent EEG sources: a cross-sectional and longitudinal study
Huang C; Wahlund LO; Dierks T; Julin P; Winblad B; Jelic V
Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2000;69(5):630-635
Visual rating and volumetry of the medial temporal lobe on magnetic resonance imaging in dementia: a comparative study
Wahlund LO; Julin P; Johansson SE; Scheltens P
Article: CLINICAL NEUROPHYSIOLOGY. 2000;111(10):1817-1824
Spatial pattern of cerebral glucose metabolism (PET) correlates with localization of intracerebral EEG-generators in Alzheimer's disease
Dierks T; Jelic V; Pascual-Marqui RD; Wahlund LO; Julin P; Linden DEJ; Maurer K; Winblad B; Nordberg A
Article: NEUROBIOLOGY OF AGING. 2000;21(4):533-540
Quantitative electroencephalography in mild cognitive impairment: longitudinal changes and possible prediction of Alzheimer's disease
Jelic V; Johansson SE; Almkvist O; Shigeta M; Julin P; Nordberg A; Winblad B; Wahlund LO
Article: ALZHEIMER'S REPORTS. 2000;3(5-6):275-280
Temporal lobe atrophy and spatial aspects of brain electrical activity in Alzheimer's disease
Huang C; Julin P; Jelic V; Dierks T; Winblad B; Wahlund LO
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 1999;10(6):526-533
A follow-up study of the family with the Swedish APP 670/671 Alzheimer's disease mutation
Wahlund LO; Basun H; Almkvist O; Julin P; Axelman K; Shigeta M; Jelic V; Nordberg A; Lannfelt L
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 1999;10(4):262-268
Inheritance of the ApoE ε4 allele increases the rate of brain atrophy in dementia patients
Wahlund LO; Julin P; Lannfelt L; Lindqvist J; Svensson L
Article: PSYCHIATRY RESEARCH. 1999;90(3):193-199
Visual assessment of medial temporal lobe atrophy in demented and healthy control subjects: correlation with volumetry
Wahlund LO; Julin P; Lindqvist J; Scheltens P
Article: ALZHEIMER DISEASE & ASSOCIATED DISORDERS. 1998;12(1):49-53
Brain volumes and regional cerebral blood flow in carriers of the Swedish Alzheimer amyloid protein mutation
Julin P; Almkvist O; Basun H; Lannfelt L; Svensson L; Winblad B; Wahlund LO
Article: NEUROREPORT. 1998;9(1):157-160
EEG slowing and cerebrospinal fluid tau levels in patients with cognitive decline
Jelic V; Blomberg M; Dierks T; Basun H; Shigeta M; Julin P; Jensen M; Lannfelt L; Winblad B; Wahlund LO
Article: PSYCHIATRY RESEARCH. 1997;76(1):41-49
Reliability of interactive three-dimensional brain volumetry using MP-RAGE magnetic resonance imaging
Julin P; Melin T; Andersen C; Isberg B; Svensson L; Wahlund LO
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 1997;8(6):343-347
Global Dimensional Complexity of multichannel EEG in mild Alzheimer's disease and age-matched cohorts
Yagyu T; Wackermann J; Shigeta M; Jelic V; Kinoshita T; Kochi K; Julin P; Almkvist O; Wahlund LO; Kondakor I; Lehmann D
Article: ARCHIVES OF NEUROLOGY. 1997;54(10):1294-1299
Bilateral temporal lobe volume reduction parallels cognitive impairment in progressive aphasia
Andersen C; Dahl C; Almkvist O; Ostberg P; Julin P; Wahlund LO
Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 1997;63(1):59-65
Apolipoprotein E epsilon 4 allele decreases functional connectivity in Alzheimer's disease as measured by EEG coherence
Jelic V; Julin P; Shigeta M; Nordberg A; Lannfelt L; Winblad B; Wahlund LO
Article: JOURNAL OF NUCLEAR MEDICINE. 1997;38(6):914-919
MRI-guided SPECT measurements of medial temporal lobe blood flow in Alzheimer's disease
Julin P; Lindqvist J; Svensson L; Slomka P; Wahlund LO
Article: JOURNAL OF NEURAL TRANSMISSION. 1997;104(4-5):483-495
EEG-microstates in mild memory impairment and Alzheimer's disease: Possible association with disturbed information processing
Dierks T; Jelic V; Julin P; Maurer K; Wahlund LO; Almkvist O; Strik WK; Winblad B
Article: DEMENTIA. 1996;7(6):314-323
Quantitative electroencephalography power and coherence in Alzheimer's disease and mild cognitive impairment
Jelic V; Shigeta M; Julin P; Almkvist O; Winblad B; Wahlund LO
Article: MAGNETIC RESONANCE IMAGING. 1996;14(6):601-608
MRI in successful aging, a 5-year follow-up study from the eighth to ninth decade of life
Wahlund LO; Almkvist O; Basun H; Julin P
Article: ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY. 1995;95(2):77-83
EEG IN SUCCESSFUL AGING - A 5-YEAR FOLLOW-UP-STUDY FROM THE 8TH TO 9TH DECADE OF LIFE
SHIGETA M; JULIN P; ALMKVIST O; BASUN H; RUDBERG U; WAHLUND LO
Article: DEMENTIA. 1995;6(3):142-147
CLINICAL-DIAGNOSIS OF FRONTAL-LOBE DEMENTIA AND ALZHEIMERS-DISEASE - RELATION TO CEREBRAL PERFUSION, BRAIN ATROPHY AND ELECTROENCEPHALOGRAPHY
JULIN P; WAHLUND LO; BASUN H; PERSSON A; MARE K; RUDBERG U
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All other publications

Meeting abstract: NEUROIMAGE. 2010;52:S142
Quantification and wavelet-aided parametric imaging of cerebral amyloid using the HRRT PET-system and [18F]AZD4694
Cselenyi Z; Jonhagen ME; Forsberg A; Halldin C; Julin P; Schou M; Johnstroem P; Varnas K; Svensson S; Farde L
Meeting abstract: NEUROBIOLOGY OF AGING. 2004;25:S312
Intracranial volume in mild cognitive impairment, Alzheimer's disease and vascular dementia. evidence for brain reserve?
Wolf H; Julin P; Gertz HJ; Winblad B; Wahlund LO
Corrigendum: ACTA NEUROLOGICA SCANDINAVICA. 2003;108(1):68
A critical discussion of the role of neuroimaging in mild cognitive impairment. (vol 107, pg 52, 2003)
Wolf H; Jelic V; Gertz HJ; Nordberg A; Julin P; Wahlund LO
Review: ACTA NEUROLOGICA SCANDINAVICA, SUPPLEMENT. 2003;107:52-76
A critical discussion of the role of neuroimaging in mild cognitive impairment
Wolf H; Jelic V; Gertz HJ; Nordberg A; Julin P; Wahlund LO
Thesis / dissertation: 1997
MRI and SPECT neuroimaging in mild cognitive impairment and Alzheimer's disease
Julin, Per

Employments

Affiliated to Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2025-2027

Degrees and Education

University Medical Degree, Karolinska Institutet, 1990

About me

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