SOSVASC – David Lindström's research group

The SOSVASC group focuse on vascular disorders such as aortic aneurysms, aortic dissections, carotid stenosis, peripheral arterial disease, thoracic outlet syndromes. We also have a research focus on wounds, trauma and vascular nursing.

Part of the:

The Vascular Surgery Research Group KI SÖS

SOSVASC is an active Clinical Research group with around 15 members in Vascular Surgery, Trauma, Wound care, and Nursing Research. In addition to collaborations within KI SÖS, we have established collaborations with other groups at KI, as well as with external universities both nationally and internationally.

Publications

Selected publications

Staff and contact

Group leader

All members of the group

Research

Projects

Carotid disease

  1. Preventing complications during carotid surgery & stenting.
  2. Biomarkers and cellular mechanisms to predict unstable arterioscleroses.

Aortic disease

  1. In Situ Laser Fenestrations (ISLF) for complex aortic disease.
  2. Aortic aneurysm; operative technique (RENOFIX study), hereditary aspects and screening.
  3. Metformin for small AAA – MAAAGI trial
  4. Ruptured abdominal aortic aneurysm – patient characteristics, x-ray findings and results of treatment.
  5. TEVAR for uncomplicated dissection – SUNDAY trial. Mapping prevalence of Dissection, and treatment outcomes of aortic dissection.
  6. FEVAR and BEVAR technique for visceral arteries. COSI FEVAR study

Thoracic Outlet Syndrome

  1. Multiple clinical investigations on Venous TOS
  2. Mutliple clinical investigations on Neurogenic TOS

Peripheral artery disease (PAD)

  1. SWEDEPAD trial.
  2. CLARITY trial.
  3. PAD and diabetes; mechanisms for ischemia and long term results.
  4. Risk factors for worsened outcome after amputation preceded by a vascular intervention.
  5. Evaluation of patient centered follow-up program after vascular intervention for claudication.

Trauma/ Wounds

  1. Long term follow-up for patients treated for traumatic aortic injury.
  2. Evaluation and improvement of surgical methods in blast and gun wounds.
  3. Negative pressure dressings – clinical outcomes.

Completed studies

  1. Swedepad I+II: National Swedish randomized study comparing balloons and stents with – and without – drug eluting mechanism for patients with PAD.
  2. ACST-2: Asymptomatic Carotid Surgery Trial. Large international randomized trial comparing carotid endarterectomy vs. carotid artery stenting in patients with asymptomatic carotid stenosis. 
  3. Basil-2 study: A multi-centre randomised controlled trial to find out if a ‘vein bypass first’ or a ‘best endovascular first’ revascularisation strategy is best in patients with severe CLTI 

Collaborations

  • Prof A Holden and Dr A Dean, Auckland University, New Zealand.
  • Prof A Bradbury, University of Birmingham, England.  
  • Prof A Wanhainen and Prof K Mani, Uppsala University Hospital.
  • W Yoon, MedStar Washington Hospital Center, USA.
  • Prof U Hedin Research Group, Department of Molecular Medicine and Surgery, Karolinska Institutet.
  • MD H Yee Harry Yu, Hong Kong University.
  • Karolinska University Hospital. Prof R Hultgren, STAR-Stockholm Aneurysm Research Group.
  • Prof Mario Lachat, Universitätsspital Zürich.
  • Prof J Frostegård, Unit of Immunology and Chronic Disease, Karolinska Institutet.
  • MD K Österberg, University of Gothenburg, Wallenberg Laboratory, University of Gothenburg.
  • Prof J von Schreeb, Department of Public Health Sciences, Karolinska Institutet.
  • A Prof B Sigvant, Centralsjukhuset i Karlstad.
Keywords:
Aortic Aneurysm Aortic Dissection Cardiology and Cardiovascular Disease Carotid Stenosis Dissection, Thoracic Aorta Show all
Content reviewer:
David Lindström
25-03-2026