Skip to main content

Previous research projects at HIC

Below are some of the projects HIC has been working with over the past few years. The research focuses on clinical informatics in the areas Patient Centred Information Systems, Decision support and Decision making.

MobEVAL – evaluation of mobile ICT in homecare

The introduction of electronic health records (EHRs), clinical decision support systems (CDSS) and other IT systems in primary health care have simplified the daily work but also resulted in increased time for administration. Yet, although IT has been used in health care for decades we still only use a fraction of the potential of modern information technologies. Employees in primary health care still depend on desktop computers in order to carry out documentation and other care related administrative work, despite a large part of primary care work is performed in the patient's home. Mobile EHRs have been shown to improve the documentation quality, yet knowledge about current adoption in the Swedish context and the impact of such tools remain low.

The purpose of this research project is to explore how the implementation of mobile IT-systems in home care affects the work of health care professionals. In order to achieve this aim, we will:

  1. explore the current state of implementation of mobile IT-systems in home care, and
  2. examine how the implementation of new mobile IT-systems affects healthcare professionals’ work situation, specifically focusing on administration time, working environment (mainly in terms of experienced stress) and healthcare professionals perception of patient safety in relation to documentation, access to information and communication tools in mobile work situations.

There are many different evaluation methods and tools to be applied, yet guidance on what approaches are most suitable to apply and what factors are most important to evaluate is limited. We believe that this has a negative impact on the number of evaluation studies performed of mobile IT-systems in homecare and their quality. In parallel with the evaluation study, we will therefore also develop a framework for evaluation of mobile IT-systems in healthcare, with the primary user group healthcare professionals.

Participating researchers

Computer-interpretable guidelines through openEHR

Integration of computer-interpretable guidelines with openEHR

The focus of this research is to offer new ways of supporting clinical processes through the use of information technology that is based on reusable evidence-based data structures, models and components. In the long term this can lead to the creation of customizable e-services for patient-specific decision making in health care. In particular, computerisation of clinical practice guidelines will be explored using openEHR, a semantic technology for electronic health records.

The project is a collaboration between the KI departments LIME, MedSolna and Clinical Neuroscience as well as with the company Cambio Healthcare Systems.

Project members are Sabine Koch, LIME; Michael Fored, MedSolna; Rong Chen, Cambio Healthcare Systems and LIME; Tiago Prazeres Moreira, Clinical Neuroscience.


Retrospective checking of compliance with practice guidelines for acute stroke care: a novel experiment using openEHR's Guideline Definition Language.
Anani N, Chen R, Prazeres Moreira T, Koch S
BMC Med Inform Decis Mak 2014 May;14():39

Early Experiences from a guideline-based computerized clinical decision support for stroke prevention in atrial fibrillation.
Chen R, Valladares C, Corbal I, Anani N, Koch S
Stud Health Technol Inform 2013 ;192():244-7

OpenEHR-based representation of guideline compliance data through the example of stroke clinical practice guidelines.
Anani N, Chen R, Prazeres Moreira T, Koch S
Stud Health Technol Inform 2012 ;180():487-91

Heart Rate Variability Biofeedback Game

Reduced heart rate variability (HRV) is an indicator of a malfunctioning autonomic nervous system, which could be a cause or consequence of disease.
Resonant frequency breathing is a potential non-invasive means of intervention for improving the balance of the autonomic nervous system and increasing HRV. However, such breathing exercises are regarded as boring and monotonous tasks. The use of gaming elements (gamification) or even the creation of a full gaming experience is a well-recognised method for achieving higher motivation and engagement in various tasks. However, there is limited documented knowledge on how to design a game for health purposes, e.g., breathing exercises. In particular, the influence of additional interactive elements on the main course of training has not yet been explored.

In a collaboration with the School of Technology and Health, Royal Institute of Technology, we evaluated the satisfaction levels achieved using different game elements and how disruptive they were to the main task, i.e., paced breathing training. An Android flight game was developed with three game modes that differ in the degrees of multitasking they require. Design, development and evaluation were conducted using a user-centred approach, including context analysis, the design of game principle mock-ups, the selection of game principles through a survey, the design of the game mechanics and GUI mock-up, icon testing and the performance of a summative study through user questionnaires and interviews. A summative evaluation of the developed game was performed with healthy participants (ages 40-67) in a controlled setting.

The results confirm the potential of video games for motivating players to engage in HRV biofeedback training. The highest training performance on the first try was achieved through pure visualisation rather than in a multitasking mode. However, players had higher motivation to play the more challenging game and were more interested in long-term engagement. This project will be followed by recruiting people suffering from depression and stress to evaluate the games.

Contact person

Aboozar Eghdam


The goal of IntegrIT is to develop an infrastructure for patient-oriented clinical research that integrates data collection from patient records, research templates and patients' self-reporting. The aim is to promote clinical research in the regular care while reducing administrative time for both researchers and patients.

My Care Pathways

The project My Care Pathways strives towards the vision to enable citizens to track their health by providing them online access to past history, current state and prospective future events regarding their personal care pathways.

My Care Plan

My care plan is a study on supporting self-care and collaboration in stroke care through information and communication technology. The main purpose of our research is to examine how health information systems (in this context 'My care plan') used by patients with chronic or long-term illnesses should be designed to improve collaboration, patient participation, autonomy and self-care. In this project we will therefore develop a prototype 'My care plan' that will be a tool with a focus on care and rehabilitation planning as a means to improve collaboration between patients and healthcare staff and a tool to enable long-term reporting and monitoring of individual's health status.

This project is financed by the Health Informatics Centre (HIC). Project time: 2011-2016.

Contact person

Maria Hägglund

National study of eHealth in ambulance care

A questionnaire study to describe how information and communication technology (ICT) or eHealth is used in ambulance care is performed during 2016. The questionnaire was sent out to ambulance nurses, with the purpose to explore how eHealth supports the nurses information needs during the different phases of the ambulance workflow. The study was performed on behalf of the Swedish eHealth Agency (eHälsomyndigheten) in collaboration between the Swedish Association of Health Professionals (Vårdförbundet), Riksföreningen för ambulanssjuksköterskor and Karolinska Institutet.

Vårdförbundet coordinates the work and distributes the questionnaires to all ambulance nurses in their membership registry. Researchers from the Health Informatics Centre and Sektionen för Omvårdnad at Karolinska institutet are responsible to analyzing the data and reporting the results.

Read more about it at ehälsomyndigheten (in Swedish)

Read more about it at Dagens Medicin (in Swedish)

Participating researchers from HIC

Maria Hägglund

Therese Scott Duncan


Collaborative interaction points in post-discharge stroke care.
Davoody N, Koch S, Krakau I, Hägglund M
Int J Integr Care 2014 Oct;14():e032

Supporting persons with mild acquired cognitive impairments through e-services

The objective of this research is to present an overview of the mild/moderate acquired cognitive impairment (MACI) persons’ experience with e-services such as social media, mobile and assistive technology.

This project started with an exploratory study exploring the current assistive information and communication technology (ICT) as a systematic review of the existing literature about available ICT tools for MACI patients using 8 different medical, scientific, engineering, and physiotherapy library databases. The functionality of tools was analyzed using an analytical framework based on the International Classification of Functioning, Disability and Health (ICF). The research was followed by a postal self-administered questionnaire, asking a total of 600 members of a patient organization (Hjärnkraft) regarding the persons’ use of e-services and social media in addition to their cognitive failures level. The project will be followed by an evaluation of a public Facebook group established for people with fatigue after an injury to the brain in addition to a few focus groups meeting with a small number of persons with MACI. So far, the results of different studies of this project showed a lack of special ICT tools for supporting people with MACI in addition to what available services/tools have been used by them frequently (on their own). The results also indicated that communication is the most important aspect of e-services for them.

Contact person

Aboozar Eghdam


Information and communication technology to support self-management of patients with mild acquired cognitive impairments: systematic review.
Eghdam A, Scholl J, Bartfai A, Koch S
J. Med. Internet Res. 2012 Nov;14(6):e159