Histiocytoses and Hematology

The major aim of our studies is to improve survival and reduce long-term sequelae in children affected by cancer and blood disorders, with focus on hematological disorders and the histiocytoses (hemophagocytic lymphohistiocytosis, HLH, and Langerhans cell histiocytosis, LCH).

Our goal is to develop better diagnostic and monitoring tools, and better treatments. Our studies have resulted in significantly improved survival for patients affected by HLH, worldwide.

With the ultimate goal to improve treatment and outcome, we also investigate underlying genetics, immunology and biology of the disorders. Our studies range from molecular biology, through cellular studies to clinical and epidemiological studies. They comprise the following main research areas.

Main research areas

  • Hemophagocytic Lymphohistiocytosis (HLH)
  • Langerhans Cell Histiocytosis (LCH)
  • Acute leukemias


The main research projects are presented more in detail here


Research group leader

Group members

Désirée Gavhed, PhD; Research coordinator
Elisabet Bergsten, PhD; Research coordinator, Data manager
Ida Hed Myrberg, BSc; Statistician
Indranil Sinha, PhD; Bioinformatician
Nikolas Herold, MD; Dr. med, Assistant professor; Resident in pediatrics
Frida Holm, PhD; Assistant professor
Magdalini Lourda, PhD; Assistant professor (affiliated)
AnnaCarin Horne, MD; PhD, Senior researcher; Consultant
Selma Olsson Åkefeldt, MD, PhD; Pediatrician
Maja Ideström, MD, PhD; Senior Consultant
Marie Meeths, MD, PhD; Pediatrics
Shahrzad Shirazi Fard, PhD; Assistant professor
Daniel Hagey, PhD; Postdoc (affiliated)
Ingrid Lilienthal, PhD; Medical student; Teaching assistant

PhD students

Tatiana von Bahr Greenwood, MD; Paediatrician
Alexandra Löfstedt, MD; Resident in pediatrics
Egle Kvedaraite, MD; Board certified physician
Nikolaos Tsesmetzis, MSc
Maria Sjöborg Alpman, MD; Pediatrician, Consultant