Nikolaos Tsesmetzis

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Articles

Article: BLOOD. 2024;143(19):1953-1964
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma
Morsy MHA; Lilienthal I; Lord M; Merrien M; Wasik AM; Sureda-Gomez M; Amador V; Johansson HJ; Lehtio J; Garcia-Torre B; Martin-Subero JI; Tsesmetzis N; Tao S; Schinazi RF; Kim B; Sorteberg AL; Wickstrom M; Sheppard D; Rassidakis GZ; Taylor IA; Christensson B; Campo E; Herold N; Sander B
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(6):925-940
Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial
Jadersten M; Lilienthal I; Tsesmetzis N; Lourda M; Bengtzen S; Bohlin A; Arnroth C; Erkers T; Seashore-Ludlow B; Giraud G; Barkhordar GS; Tao S; Fogelstrand L; Saft L; Ostling P; Schinazi RF; Kim B; Schaller T; Juliusson G; Deneberg S; Lehmann S; Rassidakis GZ; Hoglund M; Henter J-I; Herold N
Article: CANCERS. 2022;14(12):2939
ALK plus Anaplastic Large Cell Lymphoma (ALCL)-Derived Exosomes Carry ALK Signaling Proteins and Interact with Tumor Microenvironment
Chioureas D; Beck J; Baltatzis G; Vardaki I; Fonseca P; Tsesmetzis N; Vega F; Leventaki V; Eliopoulos AG; Drakos E; Rassidakis GZ; Panaretakis T
Article: EMBO MOLECULAR MEDICINE. 2020;12(3):e10419
Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy
Rudd SG; Tsesmetzis N; Sanjiv K; Paulin CBJ; Sandhow L; Kutzner J; Myrberg IH; Bunten SS; Axelsson H; Zhang SM; Rasti A; Makela P; Coggins SA; Tao S; Suman S; Branca RM; Mermelekas G; Wiita E; Lee S; Walfridsson J; Schinazi RF; Kim B; Lehtio J; Rassidakis GZ; Tamm KP; Warpman-Berglund U; Heyman M; Grander D; Lehmann S; Lundback T; Qian H; Henter J-I; Schaller T; Helleday T; Herold N
Article: CANCERS. 2019;11(10):E1479-1479
STAT3 Activity Promotes Programmed-Death Ligand 1 Expression and Suppresses Immune Responses in Breast Cancer
Zerdes I; Wallerius M; Sifakis EG; Wallmann T; Betts S; Bartish M; Tsesmetzis N; Tobin NP; Coucoravas C; Bergh J; Rassidakis GZ; Rolny C; Foukakis T
Article: BLOOD CANCER JOURNAL. 2018;8(11):98
Low-level expression of SAMHD1 in acute myeloid leukemia (AML) blasts correlates with improved outcome upon consolidation chemotherapy with high-dose cytarabine-based regimens
Rassidakis GZ; Herold N; Myrberg IH; Tsesmetzis N; Rudd SG; Henter J-I; Schaller T; Ng S-B; Chng WJ; Yan B; Ng CH; Ravandi F; Andreeff M; Kantarjian HM; Medeiros LJ; Xagoraris I; Khoury JD
Article: SCIENTIFIC REPORTS. 2016;6:21252
Potential role of AKT/mTOR signalling proteins in hairy cell leukaemia: association with BRAF/ERK activation and clinical outcome
Lakiotaki E; Levidou G; Angelopoulou MK; Adamopoulos C; Pangalis G; Rassidakis G; Vassilakopoulos T; Gainaru G; Flevari P; Sachanas S; Saetta AA; Sepsa A; Moschogiannis M; Kalpadakis C; Tsesmetzis N; Milionis V; Chatziandreou I; Thymara I; Panayiotidis P; Dimopoulou M; Plata E; Konstantopoulos K; Patsouris E; Piperi C; Korkolopoulou P

All other publications

Thesis / dissertation: 2023
Translational studies on antimetabolic therapies in paediatric oncology
Tsesmetzis, Nikolaos
Review: CANCERS. 2018;10(7):E240-240
Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism
Tsesmetzis N; Paulin CBJ; Rudd SG; Herold N
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2018;180(5):744-748
CD274 (PD-L1)/PDCD1 (PD-1) expression in de novo and transformed diffuse large B-cell lymphoma
Kwiecinska A; Tsesmetzis N; Ghaderi M; Kis L; Saft L; Rassidakis GZ
Letter: LEUKEMIA. 2017;31(7):1633-1637
PD-L1 is commonly expressed and transcriptionally regulated by STAT3 and MYC in ALK-negative anaplastic large-cell lymphoma
Atsaves V; Tsesmetzis N; Chioureas D; Kis L; Leventaki V; Drakos E; Panaretakis T; Grander D; Medeiros LJ; Young KH; Rassidakis GZ

Employments

Postdoctoral Researcher, Department of Women's and Children's Health, Karolinska Institutet, 2023-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Women's and Children's Health, Karolinska Institutet, 2023

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