Agneta Månsson-Broberg

Agneta Månsson-Broberg

Adjunct Lecturer | Affiliated to Research | Docent
Telephone: +46852483845
Visiting address: M 52, Karolinska Universitetssjukhuset Huddinge, 14186 Stockholm
Postal address: H7 Medicin, Huddinge, H7 ICCA Braunschweig Månsson-Broberg, 171 77 Stockholm

Articles

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Grants

  • Swedish Research Council
    1 January 2024 - 31 December 2025
    Aims: The specific aims of the pilot study is to provide data to prepare for a future national, open-label proof of concept clinical treatment study assessing the safety and efficacy  interleukin 6 inhibition (IL6i) for the treatment of immune checkpoint inhibitor (ICI) related myocarditis (ICIrM). Background:  ICIrM is a rare complication to ICI cancer therapy but  the increasing number of patients in combination with a reported mortality of 30-40% summons up to a significant clinical problem. Current treatment guidelines with high dose cortisone are based on retrospectiv data. IL6 is used for  other irAEs, and we suggest a national open -label proof of concept clinical treatment study to asses early IL6i in the treatment of ICIrM. Methods: We will perform a systematic review covering clinical data on IL6 blockade for ICIrM treatments  according to the PRISMA framework (2024) and a retrospective single center study of diagnosis, management and cardiovascular och cancer outcome i patients with ICIrM at Karolinska University Hospital (2024). These subprojects will be the base for planning and preparing the future treatment study, The project organisation and steering committe is a multidisciplinary team to secure all aspects of optimal dimensioning, patient eligbility, outcome measures. This group will also be the steering committe for the national ICIrM network to provide a base for future treatment study.

Employments

  • Affiliated to Research, Department of Women's and Children's Health, Karolinska Institutet, 2023-2026
  • Adjunct Lecturer, Department of Medicine, Huddinge, Karolinska Institutet, 2019-2025

Degrees and Education

  • Docent, Karolinska Institutet, 2023
  • Degree Of Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2009
  • University Medical Degree, Karolinska Institutet, 1994

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