Kirsi Jahnukainen
Affiliated to Teaching/Tutoring | Docent
E-mail: kirsi.jahnukainen@ki.se
Visiting address: BioMedicum A4, Solnavägen 9, 17165 Solna
Postal address: K6 Kvinnors och barns hälsa, K6 Barnonkologi och Barnkirurgi Stukenborg, 171 77 Stockholm
About me
- I am visiting professor of Pediatric Oncology at the Department of Women's
and Children's Health, Pediatric Endocrinology Unit, Karolinska Institutet
and University Hospital, Stockholm, Sweden. I am a founding member of
NORDFERTIL (www.nordfertil.org) and an associated partner of EU-ITN
consortium “GROWSPERM” (www.growsperm.eu). I am working also as a senior
consultant in pediatric hematology and oncology in Children’s Hospital,
Helsinki University Central Hospital.
COURSES AND DEGREES
M.D., University of Turku, 1992
Specialist in Pediatrics, University of Turku, 2002
Specialist in Pediatrics in Sweden, 2003
Specialist in Medical Leadership, University of Turku, 2005
Specialist in Pediatric Hematology and Oncology, Helsinki University, 2006
DOCTORAL DEGREE
PhD, University of Turku, 1995
POSTDOC APPOINTMENTS
Post-doctoral scientist, Professor Stefan Schlatt´s lab, Centre for Research
in Reproductive Physiology, University of Pittsburgh, USA, 7/2005- 6/2006
Post-doctoral scientist, Professor Olle Söder´s lab, Department of Women´s
and Children´s Health, Karolinska Institutet , 8/1998-12/1999
DOCENT-LEVEL COMPETENCE
Docent in Clinical Pediatric Hematology and Oncology, Helsinki University,
2012
Docent in Experimental Pediatric Hematology and Oncology, Helsinki
University, 2008
Docent in Pediatrics, Karolinska Institutet, 2002
Research
- We focus on late adverse effects among adult survivors of childhood cancer,
and pediatric hematopoietic stem cell transplantation.
We have shown that survivors after pediatric hematopoietic stem cell
transplantation are at risk of early gonadal, skeletal and vascular aging and
frailty. Our research group is exploring methods to predict and prevent
gonadal late effects.
The clinical aim is to establish clinical quality testing of cryopreserved
immature ovarian and testicular tissue collected for fertility preservation.
Teaching
- Ongoing supervision of a PhD candidate:
• M.D. Mari Wilhelmsson, (Late adverse effects
after allogeneic hematopoietic stem cell transplantation in childhood AML),
Department of Women´s and Children´s Health, Pediatric Endocrinology Unit,
Karolinska Institutet, Sweden, registration 10/2011. Main supervisor.
• M.D. Valentina Pampanini (Biomarkers indicating
residual ovarian pool and their impact to determine fertility preservation
methods in childhood cancer patients) in Department of Women´s and
Children´s Health, Pediatric Endocrinology Unit, Karolinska Institutet,
Sweden, registration 2/2015. Main supervisor.
• M.D. Melanie Poganitsch, (Male fertility, late
morbidity and agining after childhood cancer) Children’s Hospital, Helsinki
University, Helsinki University Central Hospital, registration 12/2011. Main
supervisor.
PhD candidates supervised up to the defence of the candidate’s doctoral
thesis:
As main supervisor
• Mi Hou (Novel strategies and putative risks for
preservation of male fertility in acute leukemia) in Department of Women´s
and Children´s Health, Pediatric Endocrinology Unit, Karolinska Institutet,
Sweden, dissertation 26.10.2007.
• Mirja Nurmio (Models to study cancer therapy
related toxicity in immature testis) in Department of Anatomy, University of
Turku, Finland, dissertation 6.6.2009.
• M.D. Anu Vatanen, (Late adverse effects after
autologous hematopoietic stem cell transplantation in childhood) Children’s
Hospital, Helsinki University, Helsinki University Central Hospital,
dissertation 10.6.2016.
• McS Babak Asadi Azarbaijani (Novel methods to
preserve fertility in young female cancer patients) in Department for Women &
Children’s Health, Oslo University Central Hospital, dissertation 2.3.2017.
As co-supervisor
• Mona-Lisa Strand (Antimicrobial and xenobiotic
defence in the mammalian testis) in Department of Women´s and Children´s
Health, Pediatric Endocrinology Unit, Karolinska Institutet, Sweden,
dissertation 15.6.2012.
• McS Ahmed Reda (Artificial testis to study early
gonadal development and germ cell differentiation) in Department of Women´s
and Children´s Health, Pediatric Endocrinology Unit, Karolinska Institutet,
Sweden, dissertation, 30.9.2016.
Articles
- Article: AMERICAN JOURNAL OF HEMATOLOGY. 2024;99(7):1403-1406
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2024;42(18):2174-2185
- Article: INTERNATIONAL JOURNAL OF CANCER. 2024;154(12):2121-2131
- Article: INTERNET INTERVENTIONS. 2024;36:100739
- Article: HUMAN REPRODUCTION OPEN. 2024;2024(2):hoae010
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2024;204(2):595-605
- Article: CANCER. 2023;129(22):3633-3644
- Article: BLOOD ADVANCES. 2023;7(21):6532-6539
- Article: REPRODUCTIVE BIOMEDICINE ONLINE. 2023;47(4):103287
- Article: INTERNATIONAL JOURNAL OF CANCER. 2023;153(3):644-653
- Article: BLOOD. 2023;141(23):2853-2866
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2023;201(4):757-765
- Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2023;108(4):851-856
- Article: BLOOD ADVANCES. 2023;7(6):1045-1055
- Article: HUMAN REPRODUCTION. 2023;38(3):359-370
- Article: LEUKEMIA. 2023;37(3):550-559
- Article: CELL REPORTS. 2023;42(1):111907
- Article: BONE MARROW TRANSPLANTATION. 2023;58(1):39-45
- Article: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 2022;41(8):e335-e338
- Article: CANCERS. 2022;14(14):3310
- Article: SCIENTIFIC REPORTS. 2022;12(1):10670
- Article: BONE MARROW TRANSPLANTATION. 2022;57(5):705-711
- Article: BLOOD ADVANCES. 2022;6(1):152-164
- Article: BLOOD. 2021;138(23):2441-2445
- Article: NATURE MEDICINE. 2021;27(10):1806-1817
- Article: FAMILIAL CANCER. 2021;20(4):305-316
- Article: EUROPEAN JOURNAL OF CANCER. 2021;154:147-156
- Article: FERTILITY AND STERILITY. 2021;116(3):713-720
- Article: TRANSPLANTATION AND CELLULAR THERAPY. 2021;27(9):778.e1-778.e8
- Article: GENES. 2021;12(6):895
- Article: BLOOD ADVANCES. 2021;5(3):900-912
- Article: BONE MARROW TRANSPLANTATION. 2021;56(2):457-460
- Article: CELLS. 2021;10(2):241
- Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2021;8:715953
- Article: BMC MEDICINE. 2020;18(1):374
- Article: JOURNAL OF SEXUAL MEDICINE. 2020;17(10):2104-2107
- Article: PEDIATRIC NEPHROLOGY. 2020;35(9):1719-1728
- Article: TRANSPLANTATION AND CELLULAR THERAPY. 2020;26(9):1635-1645
- Article: PEDIATRIC BLOOD AND CANCER. 2020;67(8):e28209
- Article: JOURNAL OF CLINICAL MEDICINE. 2020;9(7):E2208-2208
- Article: MEDICINE (UNITED KINGDOM). 2020;99(28):e19919
- Article: CANCERS. 2020;12(7):E1786-1786
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2020;190(2):198-208
- Article: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 2020;146(4):953-960
- Article: HUMAN REPRODUCTION OPEN. 2020;2020(3):hoaa016
- Article: PEDIATRIC TRANSPLANTATION. 2019;23(7):e13550
- Article: HUMAN REPRODUCTION. 2019;34(9):1674-1685
- Article: REPRODUCTIVE BIOLOGY. 2019;19(2):133-138
- Article: LEUKEMIA AND LYMPHOMA. 2019;60(6):1469-1475
- Article: BONE MARROW TRANSPLANTATION. 2019;54(5):726-736
- Article: CANCER MEDICINE. 2019;8(2):527-542
- Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2019;17(1):10
- Article: NEURO-ONCOLOGY. 2019;21(1):125-136
- Article: FRONTIERS IN ENDOCRINOLOGY. 2019;10:555
- Article: JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY. 2019;41(1):e12-e17
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2018;183(4):618-628
- Article: HUMAN REPRODUCTION. 2018;33(9):1677-1683
- Article: ORPHANET JOURNAL OF RARE DISEASES. 2018;13(1):139
- Article: TRANSPLANT INTERNATIONAL. 2018;31(2):157-164
- Article: PEDIATRIC BLOOD AND CANCER. 2017;64(12)
- Article: PEDIATRIC BLOOD AND CANCER. 2017;64(12)
- Article: BONE MARROW TRANSPLANTATION. 2017;52(10):1406-1415
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2017;178(3):448-456
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2017;178(4):592-602
- Article: BONE MARROW TRANSPLANTATION. 2017;52(7):1029-1035
- Article: BONE MARROW TRANSPLANTATION. 2017;52(5):711-716
- Article: BONE MARROW TRANSPLANTATION. 2017;52(4):600-605
- Article: REPRODUCTIVE BIOLOGY. 2017;17(1):25-33
- Article: GENES CHROMOSOMES AND CANCER. 2016;55(9):719-726
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2016;174(4):600-609
- Article: CANCER. 2016;122(14):2268-2276
- Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2016;97(1):55-62
- Article: LEUKEMIA AND LYMPHOMA. 2016;57(3):700-707
- Article: PEDIATRIC BLOOD AND CANCER. 2016;63(1):83-92
- Article: HUMAN REPRODUCTION. 2015;30(11):2463-2475
- Article: PEDIATRIC BLOOD AND CANCER. 2015;62(11):2000-2006
- Article: JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY. 2015;37(7):536-542
- Article: ANDROLOGY. 2015;3(5):947-955
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2015;169(6):859-867
- Article: BONE MARROW TRANSPLANTATION. 2015;50(6):850-857
- Article: ECHOCARDIOGRAPHY. 2015;32(3):522-527
- Article: PLOS ONE. 2015;10(7):e0133985
- Article: HORMONE RESEARCH IN PAEDIATRICS. 2015;84(2):108-115
- Article: PEDIATRIC BLOOD AND CANCER. 2014;61(12):2199-2202
- Article: TRANSPLANTATION. 2014;98(9):987-993
- Article: PEDIATRIC BLOOD AND CANCER. 2014;61(9):1638-1643
- Article: GENES CHROMOSOMES AND CANCER. 2014;53(8):667-675
- Article: MOLECULAR CANCER. 2014;13:155
- Article: PEDIATRIC BLOOD AND CANCER. 2014;61(6):1094-1100
- Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2014;170(2):211-218
- Article: PEDIATRIC BLOOD AND CANCER. 2013;60(12):1988-1995
- Article: BLOOD COAGULATION AND FIBRINOLYSIS. 2013;24(7):749-756
- Article: JOURNAL OF CANCER SURVIVORSHIP. 2013;7(3):404-412
- Article: JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY. 2013;35(6):e254-e259
- Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2013;90(3):187-194
- Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2013;168(2):281-288
- Article: JOURNAL OF CLINICAL VIROLOGY. 2013;56(1):77-81
- Article: PEDIATRIC BLOOD AND CANCER. 2012;59(7):1190-1197
- Article: CANCER RESEARCH. 2012;72(20):5174-5178
- Article: BLOOD. 2012;120(5):978-984
- Article: SPERMATOGENESIS. 2012;2(2):79-87
- Article: PEDIATRIC BLOOD AND CANCER. 2011;57(7):1222-1229
- Article: BLOOD. 2011;118(22):5905-5913
- Article: REPRODUCTION. 2011;142(5):711-721
- Article: FERTILITY AND STERILITY. 2011;96(4):837-842
- Article: TRANSPLANTATION. 2011;92(4):404-409
- Article: HUMAN REPRODUCTION. 2011;26(8):1945-1954
- Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2011;254(3):267-279
- Article: BEST PRACTICE AND RESEARCH: CLINICAL ENDOCRINOLOGY AND METABOLISM. 2011;25(2):287-302
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2011;29(3):310-315
- Article: SEXUAL DEVELOPMENT. 2011;5(4):188-196
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2009;94(6):2119-2122
- Article: INTERNATIONAL JOURNAL OF ANDROLOGY. 2009;32(1):66-73
- Article: REPRODUCTIVE TOXICOLOGY. 2009;27(1):28-34
- Article: REPRODUCTIVE TOXICOLOGY. 2008;25(4):442-446
- Article: ENDOCRINOLOGY. 2008;149(6):2917-2922
- Article: REPRODUCTION. 2007;134(6):767-779
- Article: ENDOCRINOLOGY. 2007;148(11):5541-5548
- Article: HUMAN REPRODUCTION. 2007;22(7):1899-1906
- Article: HUMAN REPRODUCTION. 2007;22(5):1384-1395
- Article: HUMAN REPRODUCTION. 2007;22(4):1060-1067
- Article: CANCER RESEARCH. 2006;66(7):3813-3818
- Article: CANCER RESEARCH. 2005;65(21):9999-10005
- Article: BIOLOGY OF REPRODUCTION. 2004;70(2):290-296
- Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2003;201(1-2):39-46
- Article: ORTHODONTICS AND CRANIOFACIAL RESEARCH. 2002;5(3):131-139
- Article: ORAL ONCOLOGY. 2001;37(7):586-592
- Article: CANCER RESEARCH. 2001;61(17):6423-6427
- Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2001;68(3):590-597
- Article: CANCER RESEARCH. 2001;61(2):706-710
- Article: EUROPEAN JOURNAL OF ORAL SCIENCES. 2000;108(5):426-431
- Article: BIOLOGY OF REPRODUCTION. 2000;63(2):482-487
- Article: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 1999;115(2):131-135
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 1998;87(6):638-643
- Article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 1996;31(1-2):65-79
- Article: INTERNATIONAL JOURNAL OF ANDROLOGY. 1995;18(6):313-320
- Article: ANDROLOGIA. 1995;27(5):267-273
- Article: LEUKEMIA. 1995;9(5):908-914
- Article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 1995;28(3):263-273
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All other publications
- Letter: BONE MARROW TRANSPLANTATION. 2023;58(5):607-609
- Review: EXPERT REVIEW OF ANTICANCER THERAPY. 2022;22(11):1183-1196
- Review: TRANSPLANTATION AND CELLULAR THERAPY. 2022;28(8):503.e1-503.e15
- Letter: HAEMATOLOGICA. 2022;107(4):975-979
- Corrigendum: NATURE MEDICINE. 2021;27(12):2248
- Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(3):E74-E77
- Letter: HUMAN REPRODUCTION. 2020;35(5):1249-1251
- Review: HORMONE RESEARCH IN PAEDIATRICS. 2020;93(11-12):599-608
- Review: GENES CHROMOSOMES AND CANCER. 2018;57(7):359-365
- Review: ENDOCRINE CONNECTIONS. 2018;7(2):R69-R87
- Letter: LEUKEMIA. 2017;31(6):1460-1463
- Review: THE LANCET ONCOLOGY. 2017;18(2):e75-e90
- Review: FERTILITY AND STERILITY. 2016;106(7):1652-1657.e2
- Letter: BONE MARROW TRANSPLANTATION. 2016;51(6):853-855
- Review: CURRENT OPINION IN ENDOCRINOLOGY, DIABETES AND OBESITY. 2015;22(3):217-223
- Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2014;130(20):2050-2059
- Letter: LEUKEMIA. 2013;27(5):1183-1185
- Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2013;129(9):939-946
- Review: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2012;97(12):4341-4351
- Letter: BLOOD. 2012;119(4):1087-1088
- Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2012;128(8):858-865
- Meeting abstract: BONE. 2011;48:S255-S256
- Published conference paper: PEDIATRIC BLOOD AND CANCER. 2009;53(2):274-280
- Meeting abstract: BONE. 2009;44(2):S448
- Letter: EUROPEAN JOURNAL OF HAEMATOLOGY. 2009;82(1):75-76
- Meeting abstract: BLOOD. 2007;110(11):160B
- Published conference paper: INTERNATIONAL JOURNAL OF ANDROLOGY. 2007;30(4):366-376
- Editorial comment: INTERNATIONAL JOURNAL OF ANDROLOGY. 2007;30(4):418-419
- Review: PEDIATRIC RESEARCH. 2006;59(4):40R-47R
- Review: ENDOCRINE DEVELOPMENT. 2003;5:124-135
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Employments
- Affiliated to Teaching/Tutoring, Department of Women's and Children's Health, Karolinska Institutet, 2024-2027
Degrees and Education
- Docent, Karolinska institutet, 2002