Molecular brain imaging of neurodegenerative disorders – Andrea Varrone's research group

The main research focus of the group is the development of molecular imaging markers for the study of neurodegenerative disorders, such as Parkinson´s and Huntington´s disease, using positron emission tomography (PET).

Portrait Andrea Varrone
Andrea Varrone Photo: Andrea Varrone

Molecular brain imaging of neurodegenerative disorders

The main research focus of the group is the development of molecular imaging markers for the study of neurodegenerative disorders, such as Parkinson´s and Huntington´s disease, using positron emission tomography (PET).

The vision of the group is to develop imaging markers to study in vivo the interaction between protein misfolding, neurodegeneration and neuroinflammation. The work is based on the use of a fully translational imaging platform ranging from animal models to human subjects. The development of imaging markers makes use also of in vitro binding and autoradiographic techniques.

The preclinical and clinical research is supported by the Swedish Science Council, Vinnova, Michael J Fox Foundation for Parkinsons Research and from a private donation. Additional funding comes from AstraZeneca and CHDI Foundation.

Publications

Selected publications