Balazs Gulyas

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About me

Gulyás is a Hungarian born neurobiologist based, since 1988, in Stockholm, working at the Karolinska Institute.

Since 2013, while keeping his professorship at the Karolinska Institutet in Stockholm, he has been one of the founding professors of the Imperial College London-Nanyang Technological University's Lee Kong Chian School of Medicine in Singapore where he is responsible for Translational Neuroscience and is the Scientific Director of Neuroscience and Mental Health.

Articles

Article: JOURNAL OF NUCLEAR MEDICINE. 2019;60(12):1818-1824
Performance Evaluation of a High-Resolution Nonhuman Primate PET/CT System
Sarnyai Z; Nagy K; Patay G; Molnar M; Rosenqvist G; Toth M; Takano A; Gulyas B; Major P; Halldin C; Varrone A
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2019;29(16):2270-2274
Synthesis and biological evaluation of [¹⁸F]fluorovinpocetine, a potential PET radioligand for TSPO imaging
Nag S; Krasikova R; Airaksinen AJ; Arakawa R; Petukhovd M; Gulyas B
Article: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(502):eaan5662
The gut microbiota influences skeletal muscle mass and function in mice
Lahiri S; Kim H; Garcia-Perez I; Reza MM; Martin KA; Kundu P; Cox LM; Selkrig J; Posma JM; Zhang H; Padmanabhan P; Moret C; Gulyas B; Blaser MJ; Auwerx J; Holmes E; Nicholson J; Wahli W; Pettersson S
Article: BRAIN RESEARCH. 2019;1711:140-145
In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [¹⁸F]MNI-659
Svedberg MM; Varnas K; Varrone A; Mitsios N; Mulder J; Gulyas B; Beaumont V; Munoz-Sanjuan I; Zaleska MM; Schmidt CJ; Halldin C; Mrzljak L
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2017;37(6):2062-2075
An automated method measures variability in P-glycoprotein and ABCG2 densities across brain regions and brain matter
Kannan P; Schain M; Kretzschmar WW; Weidner L; Mitsios N; Gulyas B; Blom H; Gottesman MM; Innis RB; Hall MD; Mulder J
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2017;214(3):699-717
27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation
Ismail M-A; Mateos L; Maioli S; Merino-Serrais P; Ali Z; Lodeiro M; Westman E; Leitersdorf E; Gulyas B; Olof-Wahlund L; Winblad B; Savitcheva I; Bjorkhem I; Cedazo-Minguez A
Article: SCIENTIFIC REPORTS. 2017;7:42014
The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms
Kovacs T; Billes V; Komlos M; Hotzi B; Manzeger A; Tarnoci A; Papp D; Szikszai F; Szinyakovics J; Racz A; Noszal B; Veszelka S; Walter FR; Deli MA; Hackler LJ; Alfoldi R; Huzian O; Puskas LG; Liliom H; Tarnok K; Schlett K; Borsy A; Welker E; Kovacs AL; Padar Z; Erdos A; Legradi A; Bjelik A; Gulya K; Gulyas B; Vellai T
Article: AMERICAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;7(6):246-254
Simplified estimation of binding parameters based on image-derived reference tissue models for dopamine transporter bindings in non-human primates using [¹⁸F]FE-PE2I and PET
Odano I; Varrone A; Hosoya T; Sakaguchi K; Gulyas B; Padmanabhan P; Ghosh KK; Yang C-T; Guenther I; Wang Z; Serrano R; Chimon NG; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2016;43(12):2255-2262
Guidelines to PET measurements of the target occupancy in the brain for drug development
Takano A; Varrone A; Gulyas B; Salvadori P; Gee A; Windhorst A; Vercouillie J; Bormans G; Lammertsma AA; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2016;70(6):253-263
Brain PET measurement of PDE10A occupancy by TAK-063, a new PDE10A inhibitor, using [¹¹C]T-773 in nonhuman primates
Takano A; Stepanov V; Nakao R; Amini N; Gulyas B; Kimura H; Halldin C
Article: JOURNAL OF HUNTINGTON'S DISEASE. 2016;5(2):133-147
AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease
Billes V; Kovacs T; Hotzi B; Manzeger A; Tagscherer K; Komlos M; Tarnoci A; Padar Z; Erdos A; Bjelik A; Legradi A; Gulya K; Gulyas B; Vellai T
Article: BRAIN STRUCTURE & FUNCTION. 2016;221(3):1279-1290
Acute neuroinflammation in a clinically relevant focal cortical ischemic stroke model in rat: longitudinal positron emission tomography and immunofluorescent tracking
Toth M; Little P; Arnberg F; Haggkvist J; Mulder J; Halldin C; Gulyas B; Holmin S
Article: NEUROPHARMACOLOGY. 2016;101:519-530
A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates
Hjorth S; Karlsson C; Jucaite A; Varnas K; Hamren UW; Johnstrom P; Gulyas B; Donohue SR; Pike VW; Halldin C; Farde L
Article: AUTOPHAGY. 2016;12(2):273-286
AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects
Papp D; Kovacs T; Billes V; Varga M; Tarnoci A; Hackler LJ; Puskas LG; Liliom H; Tarnok K; Schlett K; Borsy A; Padar Z; Kovacs AL; Hegedus K; Juhasz G; Komlos M; Erdos A; Gulyas B; Vellai T
Article: EJNMMI PHYSICS. 2015;2(Suppl 1):A90
Biocompatible branched copolymer nanoparticles prepared by RAFT polymerization as MRI/PET bimodal tracers.
Yang C-T; Tao H; Jackson AW; Chandrasekharan P; Padmanabhan P; Gulyás B; Halldin C
Article: BRAIN STRUCTURE & FUNCTION. 2015;220(5):3043-3051
Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P immunoreactivity in Huntington's disease: a preliminary investigation in the postmortem human brain
Gulyas B; Sovago J; Gomez-Mancilla B; Jia Z; Szigeti C; Gulya K; Schumacher M; Maguire RP; Gasparini F; Halldin C
Article: MOLECULAR IMAGING AND BIOLOGY. 2015;17(4):445-449
Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [¹¹C]T-773
Toth M; Haggkvist J; Stepanov V; Takano A; Nakao R; Amini N; Miura S; Kimura H; Taniguchi T; Gulyas B; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2015;69(7):345-355
Evaluation of a novel PDE10A PET radioligand, [¹¹C]T-773, in nonhuman primates: Brain and whole body PET and brain autoradiography
Takano A; Stepanov V; Gulyas B; Nakao R; Amini N; Miura S; Kimura H; Taniguchi T; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2015;42(7):1119-1132
Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study
Rodriguez-Vieitez E; Ni R; Gulyas B; Toth M; Haeggkvist J; Halldin C; Voytenko L; Marutle A; Nordberg A
Article: PLOS ONE. 2015;10(5):e0125917
Positron Emission Tomography studies with [¹¹C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of Neuroinflammation
Toth M; Doorduin J; Haggkvist J; Varrone A; Amini N; Halldin C; Gulyas B
Article: MOLECULAR IMAGING AND BIOLOGY. 2014;16(2):173-179
Synthesis, Radiolabeling, and In Vivo Pharmacokinetic Evaluation of the Amyloid Beta Radioligand [¹¹C]AZD4694 in Nonhuman Primates
Schou M; Varnas K; Sandell J; Johnstrom P; Cselenyi Z; Svensson S; Nakao R; Amini N; Bergman L; Sumic A; Gulyas B; Lindstrom-Boo E; Halldin C; Farde L
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2014;68(3):89-97
Low Brain CB1 Receptor Occupancy by a Second Generation CB1 Receptor Antagonist TM38837 in Comparison With Rimonabant in Nonhuman Primates: A PET Study
Takano A; Gulyas B; Varnaes K; Little PB; Noerregaard PK; Jensen NO; Elling CE; Halldin C
Article: BIOGRAPHICAL MEMOIRS OF FELLOWS OF THE ROYAL SOCIETY. ROYAL SOCIETY (GREAT BRITAIN). 2013;59:383-406
JÁNOS SZENTÁGOTHAI. 31 October 1912 - 8 September 1994: Elected ForMemRs 20 April 1978.
Gulyás B; Somogyi P
Article: JOURNAL OF NUCLEAR MEDICINE. 2013;54(10):1825-1832
Performance Evaluation of the Small-Animal nanoScan PET/MRI System
Nagy K; Toth M; Major P; Patay G; Egri G; Haggkvist J; Varrone A; Farde L; Halldin C; Gulyas B
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2013;67(9):586-595
The dopamine D₁ receptor agonist (S)-[¹¹C]N-methyl-NNC 01-0259 is not sensitive to changes in dopamine concentrationa positron emission tomography examination in the monkey brain
Finnema SJ; Bang-Andersen B; Jorgensen M; Christoffersen CT; Gulyas B; Wikstrom HV; Farde L; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2013;40(6):747-754
Radiosynthesis and evaluation of new α₁-adrenoceptor antagonists as PET radioligands for brain imaging
Airaksinen AJ; Finnema SJ; Balle T; Varnas K; Bang-Andersen B; Gulyas B; Farde L; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40(6):921-931
In vivo imaging of the ¹⁸-kDa translocator protein (TSPO) with [¹⁸F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients
Varrone A; Mattsson P; Forsberg A; Takano A; Nag S; Gulyas B; Borg J; Boellaard R; Al-Tawil N; Eriksdotter M; Zimmermann T; Schultze-Mosgau M; Thiele A; Hoffmann A; Lammertsma AA; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2013;67(5):258-264
Brain uptake and distribution of the dopamine D3/D2 receptor partial agonist [11C]cariprazine: An in vivo positron emission tomography study in nonhuman primates
Toth M; Varrone A; Steiger C; Laszlovszky I; Horvath A; Kiss B; Gyertyan I; Adham N; Halldin C; Gulyas B
Article: EJNMMI RESEARCH. 2013;3(1):30
In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [¹⁸F]FEDAA1106
Takano A; Piehl F; Hillert J; Varrone A; Nag S; Gulyas B; Stenkrona P; Villemagne VL; Rowe CC; Macdonell R; Al Tawil N; Kucinski T; Zimmermann T; Schultze-Mosgau M; Thiele A; Hoffmann A; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2013;40(3):410-414
Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate
Schou M; Varnas K; Jucaite A; Gulyas B; Halldin C; Farde L
Article: BRAIN RESEARCH BULLETIN. 2013;91:46-51
In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB₁ receptor antagonist radioligand [¹²⁵I]SD7015 in CB₁ knock-out and wildtype mouse
Mathe D; Horvath I; Szigeti K; Donohue SR; Pike VW; Jia Z; Ledent C; Palkovits M; Freund TF; Halldin C; Gulyas B
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2013;21(1):186-195
Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity
Nag S; Kettschau G; Heinrich T; Varrone A; Lehmann L; Gulyas B; Thiele A; Keller E; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2012;53(11):1794-1801
Preclinical Characterization of a Novel Class of ¹⁸F-Labeled PET Tracers for Amyloid-β
Brockschnieder D; Schmitt-Willich H; Heinrich T; Varrone A; Gulyas B; Toth M; Andersson J; Boemer U; Krause S; Friebe M; Dinkelborg L; Halldin C; Dyrks T
Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2012;320(1-2):110-117
Evolution of microglial activation in ischaemic core and pen-infarct regions after stroke: A PET study with the TSPO molecular imaging biomarker [¹¹C]vinpocetine
Gulyas B; Toth M; Schain M; Airaksinen A; Vas A; Kostulas K; Lindstrom P; Hillert J; Halldin C
Article: EJNMMI RESEARCH. 2012;2(1):37
Synthesis and evaluation of 2-chloro N-[(S)-{(S)-1-[¹¹ C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide ([¹¹ C]N-methyl-SSR504734) as a PET radioligand for glycine transporter 1
Fuchigami T; Takano A; Gulyas B; Jia Z; Finnema SJ; Andersson JD; Nakao R; Magata Y; Haratake M; Nakayama M; Halldin C
Article: ACTA NEUROLOGICA SCANDINAVICA. 2012;125(6):373-381
Correlation between crossed cerebellar diaschisis and clinical neurological scales
Szilagyi G; Vas A; Kerenyi L; Nagy Z; Csiba L; Gulyas B
Article: BRAIN RESEARCH. 2012;1453:56-63
Signal transduction pathway activity compensates dopamine D₂/D₃ receptor density changes in Parkinson's disease: a preliminary comparative human brain receptor autoradiography study with [³H]raclopride and [³⁵S]GTPγS
Szabolcs F; Katalin N; Jia Z; Tibor H; Varrone A; Halldin C; Laszlo C; Gulyas B
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2012;20(9):3065-3071
Synthesis and evaluation of [¹⁸F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B)
Nag S; Lehmann L; Kettschau G; Heinrich T; Thiele A; Varrone A; Gulyas B; Halldin C
Article: BRAIN RESEARCH BULLETIN. 2012;87(6):504-510
The decrease of dopamine D₂/D₃ receptor densities in the putamen and nucleus caudatus goes parallel with maintained levels of CB₁ cannabinoid receptors in Parkinson's disease: A preliminary autoradiographic study with the selective dopamine D₂/D₃ antagonist [³H]raclopride and the novel CB₁ inverse agonist [¹²⁵I]SD7015
Farkas S; Nagy K; Jia Z; Harkany T; Palkovits M; Donohou SR; Pike VW; Halldin C; Mathe D; Csiba L; Gulyas B
Article: NUCLEAR MEDICINE AND BIOLOGY. 2012;39(3):315-323
Fluorine-18 labeling of three novel D-peptides by conjugation with N-succinimidyl-4-[¹⁸F]fluorobenzoate and preliminary examination by postmortem whole-hemisphere human brain autoradiography
Jahan M; Nag S; Krasikova R; Weber U; Muhs A; Pfeifer A; Spenger C; Willbold D; Gulyas B; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2012;39(2):295-303
Simplified quantification and whole-body distribution of [¹⁸F]FE-PE2I in nonhuman primates: prediction for human studies
Varrone A; Gulyas B; Takano A; Stabin MG; Jonsson C; Halldin C
Article: NEUROCHEMISTRY INTERNATIONAL. 2012;60(3):286-291
[¹²⁵I]SD-7015 reveals fine modalities of CB₁ cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's disease
Farkas S; Nagy K; Palkovits M; Kovacs GG; Jia Z; Donohue S; Pike V; Halldin C; Mathe D; Harkany T; Gulyas B; Csiba L
Article: PLOS ONE. 2012;7(7):e41457
Development of a Small D-Enantiomeric Alzheimer's Amyloid-β Binding Peptide Ligand for Future In Vivo Imaging Applications
Funke SA; Bartnik D; Glueck JM; Piorkowska K; Wiesehan K; Weber U; Gulyas B; Halldin C; Pfeifer A; Spenger C; Muhs A; Willbold D
Article: CURRENT RADIOPHARMACEUTICALS. 2012;5(1):19-28
Visualising Neuroinflammation in Post-Stroke Patients: A Comparative PET Study with the TSPO Molecular Imaging Biomarkers [¹¹C]PK11195 and [¹¹C]vinpocetine
Gulyas B; Toth M; Vas A; Shchukin E; Kostulas K; Hillert J; Halldin C
Article: NEUROCHEMISTRY INTERNATIONAL. 2012;60(2):153-162
Distribution and binding of ¹⁸F-labeled and ¹²⁵I-labeled analogues of ACI-80, a prospective molecular imaging biomarker of disease: A whole hemisphere post mortem autoradiography study in human brains obtained from Alzheimer's disease patients
Gulyas B; Spenger C; Beliczai Z; Gulya K; Kasa P; Jahan M; Jia Z; Weber U; Pfeifer A; Muhs A; Willbold D; Halldin C
Article: PSYCHOPHARMACOLOGY. 2011;218(3):579-587
Occupancy of dopamine D₂ and D₃ and serotonin 5-HT_1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography
Seneca N; Finnema SJ; Laszlovszky I; Kiss B; Horvath A; Pasztor G; Kapas M; Gyertyan I; Farkas S; Innis RB; Halldin C; Gulyas B
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2011;38(11):2058-2065
Biodistribution and radiation dosimetry of the 18 kDa translocator protein (TSPO) radioligand [¹⁸F]FEDAA1106: a human whole-body PET study
Takano A; Gulyas B; Varrone A; Karlsson P; Sjoholm N; Larsson S; Jonsson C; Odh R; Sparks R; Al Tawil N; Hoffmann A; Zimmermann T; Thiele A; Halldin C
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2011;54(20):7023-7029
Synthesis of Three Novel Fluorine-18 Labeled Analogues of L-Deprenyl for Positron Emission Tomography (PET) studies of Monoamine Oxidase B (MAO-B)
Nag S; Lehmann L; Heinrich T; Thiele A; Kettschau G; Nakao R; Gulyas B; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2011;52(8):1313-1321
Imaging of the Striatal and Extrastriatal Dopamine Transporter with ¹⁸F-LBT-999: Quantification, Biodistribution, and Radiation Dosimetry in Nonhuman Primates
Varrone A; Stepanov V; Nakao R; Toth M; Gulyas B; Emond P; Deloye JB; Vercouillie J; Stabin MG; Jonsson C; Guilloteau D; Halldin C
Article: PSYCHOPHARMACOLOGY. 2011;216(2):279-286
NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo
Takano A; Nag S; Gulyas B; Halldin C; Farde L
Article: NEUROIMAGE. 2011;56(3):1111-1121
Age and disease related changes in the translocator protein (TSPO) system in the human brain: Positron emission tomography measurements with [¹¹C]vinpocetine
Gulyas B; Vas A; Toth M; Takano A; Varrone A; Cselenyi Z; Schain M; Mattsson P; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2011;38(2):261-272
Development of a PET radioligand for the central 5-HT_1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds
Andersson JD; Pierson ME; Finnema SJ; Gulyas B; Heys R; Elmore CS; Farde L; Halldin C
Article: NEUROCHEMISTRY INTERNATIONAL. 2011;58(1):60-68
Activated MAO-B in the brain of Alzheimer patients, demonstrated by [¹¹C]-L-deprenyl using whole hemisphere autoradiography
Gulyas B; Pavlova E; Kasa P; Gulya K; Bakota L; Varszegi S; Keller E; Horvath MC; Nag S; Hermecz I; Magyar K; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2011;52(1):132-139
Kinetic Analysis and Quantification of the Dopamine Transporter in the Nonhuman Primate Brain with ¹¹C-PE2I and ¹⁸F-FE-PE2I
Varrone A; Toth M; Steiger C; Takano A; Guilloteau D; Ichise M; Gulyas B; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2010;64(10):733-741
Radiosynthesis of the Candidate β-Amyloid Radioligand [¹¹C]AZD2184: Positron Emission Tomography Examination and Metabolite Analysis in Cynomolgus Monkeys
Andersson JD; Varnas H; Cselenyi Z; Gulyas B; Wensbo D; Finnema SJ; Swahn B-M; Svensson S; Nyberg S; Farde L; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2010;64(7):573-577
Fenfluramine-Induced Serotonin Release Decreases [¹¹C]AZ10419369 Binding to 5-HT_1B-Receptors in the Primate Brain
Finnema SJ; Varrone A; Hwang TJ; Gulyas B; Pierson ME; Halldin C; Farde L
Article: NEUROCHEMISTRY INTERNATIONAL. 2010;56(6-7):789-798
The norepinephrine transporter (NET) radioligand (S,S)-[¹⁸F]FMeNER-D₂ shows significant decreases in NET density in the human brain in Alzheimer's disease: A post-mortem autoradiographic study
Gulyas B; Brockschnieder D; Nag S; Pavlova E; Kasa P; Beliczai Z; Legradi A; Gulya K; Thiele A; Dyrks T; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36(11):1885-1891
Comparative evaluations of norepinephrine transporter radioligands with reference tissue models in rhesus monkeys: (S,S)-[¹⁸F]FMeNER-D₂ and (S,S)-[¹¹C]MeNER
Takano A; Gulyas B; Varrone A; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2009;19(21):6209-6212
Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors
Donohue SR; Varnas K; Jia Z; Gulyas B; Pike VW; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2009;63(10):871-880
In Vitro Autoradiography and In Vivo Evaluation in Cynomolgus Monkey of [¹⁸F]FE-PE2I, a New Dopamine Transporter PET Radioligand
Varrone A; Steiger C; Schou M; Takano A; Finnema SJ; Guilloteau D; Gulyas B; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36(8):1308-1314
Saturated norepinephrine transporter occupancy by atomoxetine relevant to clinical doses: a rhesus monkey study with (S,S)-[¹⁸F]FMeNER-D₂
Takano A; Gulyas B; Varrone A; Maguire RP; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2009;63(5):378-389
Dopamine D_2/3 Receptor Occupancy of Apomorphine in the Nonhuman Primate Brain-A Comparative PET Study With [¹¹C]Raclopride and [¹¹C]MNPA
Finnema SJ; Halldin C; Bang-Andersen B; Gulyas B; Bundgaard C; Wikstrom HV; Farde L
Article: NEUROCHEMISTRY INTERNATIONAL. 2009;54(1):28-36
A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) system
Gulyas B; Makkai B; Kasa P; Gulya K; Bakota L; Varszegi S; Beliczai Z; Andersson J; Csiba L; Thiele A; Dyrks T; Suhara T; Suzuki K; Higuchi M; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2009;63(1):22-30
Evaluation of [¹¹C]PipISB and [¹⁸F]PipISB in Monkey as Candidate Radioligands for Imaging Brain Cannabinoid Type-1 Receptors In Vivo
Finnema SJ; Donohue SR; Zoghbi SS; Brown AK; Gulyas B; Innis RB; Halldin C; Pike VW
Article: MOLECULAR IMAGING AND BIOLOGY. 2009;11(1):23-30
Investigation of the Metabolites of (S,S)-[¹¹C] MeNER in Humans, Monkeys and Rats
Schou M; Zoghbi SS; Shetty HU; Shchukin E; Liow J-S; Hong J; Andree BA; Gulyas B; Farde L; Innis RB; Pike VW; Halldin C
Article: NEUROCHEMISTRY INTERNATIONAL. 2008;53(6-8):181-183
Immunohistoblot analysis on whole human hemispheres from normal and Alzheimer diseased brains
Beliczai Z; Varszegi S; Gulyas B; Halldin C; Kasa P; Gulya K
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2008;51(18):5608-5616
Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB₁) receptors
Donohue SR; Pike VW; Finnema SJ; Truong P; Andersson J; Gulyas B; Halldin C
Article: NEUROIMAGE. 2008;42(2):474-482
Mapping of the norepinephrine transporter in the human brain using PET with (S,S)-[¹⁸F]FMeNER-D₂
Takano A; Varrone A; Gulyas B; Karlsson P; Tauscher J; Halldin C
Article: NEUROIMAGE. 2008;41(3):1075-1085
[¹¹C]AZ10419369:: A selective 5-HT_1B receptor radioligand suitable for positron emission tomography (PET).: Characterization in the primate brain
Pierson ME; Andersson J; Nyberg S; McCarthy DJ; Finnema SJ; Varnas K; Takano A; Karlsson P; Gulyas B; Medd AM; Lee C-M; Powell ME; Heys JR; Potts W; Seneca N; Mrzljak L; Farde L; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2008;16(13):6467-6473
[¹¹C]cyclopropyl-FLB 457:: A PET radioligand for low densities of dopamine D₂ receptors
Airaksinen AJ; Nag S; Finnema SJ; Mukherjee J; Chattopadhyay S; Gulyas B; Farde L; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2008;35(3):630-636
Biodistribution and radiation dosimetry of the norepinephrine transporter radioligand (S,S)-[¹⁸F]FMeNER-D₂:: a human whole-body PET study
Takano A; Halldin C; Varrone A; Karlsson P; Sjoeholm N; Stubbs JB; Schou M; Airaksinen AJ; Tauscher J; Gulyas B
Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2008;264(1-2):9-17
Functional neuroimaging in multiple sclerosis with radiolabelled glia markers:: Preliminary comparative PET studies with [¹¹C]vinpocetine and [¹¹C]PK11195 in patients
Vas A; Shchukin Y; Karrenbauer VD; Cselenyi Z; Kostulas K; Hillert J; Savic I; Takano A; Halldin C; Gulyas B
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2008;35(1):153-157
Imaging the norepinephrine transporter with positron emission tomography:: initial human studies with (S,S)-[¹⁸F]FMeNER-D₂
Takano A; Gulyas B; Varrone A; Karlsson P; Schou M; Airaksinen AJ; Vandenhende F; Tauscher J; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2007;15(2):616-625
Synthesis of ¹¹C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET
Schou M; Pike VW; Sovago J; Gulyas B; Gallagher PT; Dobson DR; Walter MW; Rudyk H; Farde L; Halldin C
Article: BULLETIN ET MEMOIRES DE L'ACADEMIE ROYALE DE MEDECINE DE BELGIQUE. 2007;162(3-4):225-237
The receptor fingerprint of the human brain and its changes during life.
Gulyás B
Article: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2006;49(11):1007-1019
Synthesis and PET evaluation of (R)-[S-methyl-¹¹C]thionisoxetine, a candidate radioligand for imaging brain norepinephrine transporters
Schou M; Pike VW; Varrone A; Gulyas B; Farde L; Halldin C
Article: NEUROIMAGE. 2006;32(4):1690-1708
A comparison of recent parametric neuroreceptor mapping approaches based on measurements with the high affinity PET radioligands [¹¹C]FLB 457 and [¹¹C]WAY 100635
Cselenyi Z; Olsson H; Halldin C; Gulyas B; Farde L
Article: PSYCHOPHARMACOLOGY. 2006;188(1):119-127
Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion:: a PET study in nonhuman primate brain using (S,S)-[¹⁸F]FMeNER-D₂
Seneca N; Gulyas B; Varrone A; Schou M; Airaksinen A; Tauscher J; Vandenhende F; Kielbasa W; Farde L; Innis RB; Halldin C
Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2006;246(1-2):85-94
Optimization of semi-quantification in metabolic PET studies with ¹⁸F-fluorodeoxyglucose and ¹¹C-methionine in the determination of malignancy of gliomas
Borbely K; Nyary I; Toth M; Ericson K; Gulyas B
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2006;59(5):260-269
Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain:: A comparison of the agonist radioligand [^11C]MNPA and antagonist [¹¹C]raclopride
Seneca N; Finnema SJ; Farde L; Gulyás B; Wikström HV; Halldin C; Innis RB
Article: NEUROCHEMICAL RESEARCH. 2006;31(2):157-166
Continuous monitoring of post mortem temperature changes in the human brain
Gulyás B; Dobai J; Szilágyi G; Csécsei G; Székely G
Article: MOLECULAR IMAGING AND BIOLOGY. 2006;8(1):1-8
Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands:: [C-11]desipramine, [C-11]talopram and [C-11]talsupram
Schou M; Sóvágó J; Pike VW; Gulyás B; Bogeso KP; Farde L; Halldin C
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2005;58(3):173-183
[¹¹C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET
Halldin C; Lundberg J; Sóvágó J; Gulyás B; Guilloteau D; Vercouillie J; Emond P; Chalon S; Tarkiainen J; Hiltunen J; Farde L
Article: BRAIN RESEARCH BULLETIN. 2005;67(3):219-224
Lack of effect of reserpine-induced dopamine depletion on the binding of the dopamine-D3 selective radioligand, [¹¹C]RGH-1756
Sóvágó J; Farde L; Halldin C; Schukin E; Schou M; Laszlovszky I; Kiss B; Gulyás B
Article: NUCLEAR MEDICINE COMMUNICATIONS. 2005;26(8):695-700
Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[¹⁸F]FMeNER-D₂ in non-human primates
Seneca N; Andree B; Sjoholm N; Schou M; Pauli S; Mozley PD; Stubbs JB; Liow JS; Sovago J; Gulyás B; Innis R; Halldin C
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2005;22(1):65-71
Autoradiographic mapping of dopamine-D₂/D₃ receptor stimulated [³⁵S]GTPγS binding in the human brain
Sóvágó J; Makkai B; Gulyás B; Hall H
Article: NUCLEAR MEDICINE AND BIOLOGY. 2005;32(4):353-360
A preliminary PET evaluation of the new dopamine D₂ receptor agonist [¹¹C]MNPA in cynomolgus monkey
Finnema SJ; Seneca N; Farde L; Shchukin E; Sóvágó J; Gulyás B; Wikström HV; Innis RB; Neumeyer JL; Halldin C
Article: NEUROSCIENCE LETTERS. 2005;375(1):33-36
Feature uncertainty:: a novel test to probe prefrontal dysfunction in unaffected siblings of schizophrenia patients
Kéri S; Gulyás B; Benedek G; Janka Z
Article: NUCLEAR MEDICINE AND BIOLOGY. 2005;32(2):109-116
Preparation of highly specific radioactivity [¹⁸F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography
Ryzhikov NN; Seneca N; Krasikova RN; Gomzina NA; Shchukin E; Fedorova OS; Vassiliev DA; Gulyás B; Hall H; Savic I; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2005;13(3):883-893
N-Oxide analogs of WAY-100635:: new high affinity 5-HT_1A receptor antagonists
Marchais-Oberwinkler S; Nowicki B; Pike VW; Halldin C; Sandell J; Chou YH; Gulyas B; Brennum LT; Farde L; Wikström HV
Article: NEUROCHEMISTRY INTERNATIONAL. 2004;45(5):773-781
Joint explorative analysis of neuroreceptor subsystems in the human brain:: application to receptor-transporter correlation using PET data
Cselényi Z; Lundberg J; Halldin C; Farde L; Gulyás B
Article: NEUROCHEMISTRY INTERNATIONAL. 2004;45(5):609-617
Positron emission tomographic evaluation of the putative dopamine-D3 receptor ligand, [¹¹C]RGH-1756 in the monkey brain
Sóvágó J; Farde L; Halldin C; Langer O; Laszlovszky I; Kiss B; Gulyás B
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2004;53(2):57-67
PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain
Schou M; Halldin C; Sóvágó J; Pike VW; Hall H; Gulyás B; Mozley PD; Dobson D; Shchukin E; Innis RB; Farde L
Article: NEUROREPORT. 2004;15(8):1275-1277
Smelling human sex hormone-like compounds affects face gender judgment of men
Kovács G; Gulyás B; Savic I; Perrett DI; Cornwell RE; Little AC; Jones BC; Burt DM; Gál V; Vidnyánszky Z
Article: NEUROCHEMISTRY INTERNATIONAL. 2004;44(8):595-600
The putative pheromone androstadienone activates cortical fields in the human brain related to social cognition
Gulyás B; Kéri S; O'Sullivan BT; Decety J; Roland PE
Article: NEUROLOGY. 2004;62(8):1343-1351
Limbic reductions of 5-HT_1A receptor binding in human temporal lobe epilepsy
Savic I; Lindström P; Gulyás B; Halldin C; Andrée B; Farde L
Article: HUMAN BRAIN MAPPING. 2004;21(1):26-33
Feature uncertainty activates anterior cingulate cortex
Kéri S; Decety J; Roland PE; Gulyás B
Article: ORVOSI HETILAP. 2003;144(46):2271-2276
[Human positron emission tomography with oral 11C-vinpocetine].
Vas A; Christer H; Sóvágó J; Johan S; Cselényi Z; Kiss B; Kárpáti E; Lars F; Gulyás B
Article: NUCLEAR MEDICINE AND BIOLOGY. 2003;30(7):707-714
Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[¹¹C]MeNER
Schou M; Halldin C; Sóvágó J; Pike VW; Gulyás B; Mozley PD; Johnson DP; Hall H; Innis RB; Farde L
Article: ACTA NEUROLOGICA SCANDINAVICA. 2002;106(6):325-332
PET studies on the brain uptake and regional distribution of [¹¹C] vinpocetine in human subjects
Gulyás B; Halldin C; Sandell J; Karlsson P; Sóvágó J; Kárpáti E; Kiss B; Vas A; Cselényi Z; Farde L
Article: NUCLEAR MEDICINE AND BIOLOGY. 2002;29(7):753-759
Cerebral uptake of [ethyl-¹¹C]vinpocetine and 1-[¹¹C]ethanol in cynomolgous monkeys:: a comparative preclinical PET study
Gulyás B; Vas A; Halldin C; Sóvágó J; Sandell J; Olsson H; Fredriksson A; Stone-Elander S; Farde L
Article: HUMAN BRAIN MAPPING. 2002;17(1):17-27
Odorant differentiated pattern of cerebral activation:: Comparison of acetone and vanillin
Savic I; Gulyás B; Berglund H
Article: NEUROIMAGE. 2002;17(1):47-60
Wavelet-aided parametric mapping of cerebral dopamine D₂ receptors using the high affinity PET radioligand [¹¹C]FLB 457
Cselényi Z; Olsson H; Farde L; Gulyás B
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2002;29(8):1031-1038
Drug distribution in man:: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine
Gulyás B; Halldin C; Sóvágó J; Sandell J; Cselényi Z; Vas A; Kiss B; Kárpáti E; Farde L
Article: NUCLEAR MEDICINE AND BIOLOGY. 2002;29(6):651-656
PET examination of [¹¹C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter
Sandell J; Halldin C; Sovago J; Chou YH; Gulyás B; Yu MX; Emond P; Någren K; Guilloteau D; Farde L
Article: EXPERIMENTAL BRAIN RESEARCH. 2002;143(1):1-10
Perceptual segregation of overlapping shapes activates posterior extrastriate visual cortex in man
Larsson J; Amunts K; Gulyás B; Malikovic A; Zilles K; Roland PE
Article: BIOLOGIA FUTURA. 2002;53(1-2):59-66
Autoradiographic evaluation of [¹¹C]vinpocetine binding in the human postmortem brain
Hall H; Varnäs K; Sandell J; Halldin C; Farde L; Vas A; Kárpáti E; Gulyás B
Article: NEURON. 2001;31(4):661-668
Smelling of odorous sex hormone-like compounds causes sex-differentiated hypothalamic activations in humans
Savic I; Berglund H; Gulyas B; Roland P
Article: NEUROREPORT. 2001;12(9):2027-2033
Brain activation during odor perception in males and females
Bengtsson S; Berglund H; Gulyas B; Cohen E; Savic I
Article: ORVOSI HETILAP. 2001;142(9):443-449
[The effect of a single-dose intravenous vinpocetine on brain metabolism in patients with ischemic stroke].
Gulyás B; Bönöczk P; Vas A; Csiba L; Bereczki D; Boros I; Szakáll S; Balkay L; Emri M; Fekete I; Galuska L; Kerényi L; Lehel S; Márián T; Molnár T; Varga J; Trón L
Article: BRAIN RESEARCH BULLETIN. 2001;54(3):319-328
Neural networks for internal reading and visual imagery of reading:: A PET study
Gulyás B
Article: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2000;43(11):1069-1074
Radiochemical labelling of the dopamine D₃ receptor ligand RGH-1756
Langer O; Gulyás B; Sandell J; Laszlovszky I; Kiss B; Domány G; Acs T; Farde L; Halldin C
Article: HUMAN BRAIN MAPPING. 2000;11(2):104-116
Visual exploration of form and position with identical stimuli:: Functional anatomy with PET
Vidnyánszky Z; Gulyás B; Roland PE
Article: NEUROREPORT. 2000;11(13):2861-2866
PET shows that odors are processed both ipsilaterally and contralaterally to the stimulated nostril
Savic I; Gulyas B
Article: NEUROLOGY. 2000;55(4):544-548
Cerebral blood flow and glucose metabolism in mitochondrial disorders
Molnár MJ; Valikovics A; Molnár S; Trón L; Diószeghy P; Mechler F; Gulyás B
Article: NEURON. 2000;26(3):735-745
Olfactory functions are mediated by parallel and hierarchical processing
Savic I; Gulyas B; Larsson M; Roland P
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1999;11(11):4024-4036
Neuronal correlates of real and illusory contour perception: functional anatomy with PET
Larsson J; Amunts K; Gulyás B; Malikovic A; Zilles K; Roland PE
Article: JOURNAL OF NEUROIMAGING. 1999;9(4):217-222
Brain uptake and plasma metabolism of [¹¹C]vinpocetine:: A preliminary PET study in a cynomolgus monkey
Gulyás B; Halldin C; Karlsson P; Chou YH; Swahn CG; Bönöck P; Paróczai M; Farde L
Article: ORVOSI HETILAP. 1999;140(30):1687-1691
[Cerebral uptake and metabolism of (11C) Vinpocetine in monkeys: PET studies].
Gulyás B; Halldin C; Karlsson P; Chou YH; Swahn CG; Bönöczk P; Farde L
Article: NEUROREPORT. 1999;10(14):I-III
Functional neuroimaging-functional neuropathology:: The quest for validation
Gulyás B; Lestár M
Article: JOURNAL OF NEUROIMAGING. 1998;8(4):197-204
Cerebral effects of a single dose of intravenous vinpocetine in chronic stroke patients: A PET study
Szakall S; Boros I; Balkay L; Emri M; Fekete I; Kerenyi L; Lehel S; Marian T; Molnar T; Varga J; Galuska L; Tron L; Bereczki D; Csiba L; Gulyas B
Article: ACTA NEUROLOGICA SCANDINAVICA. 1998;97(5):279-286
Regional increases in [¹¹C]flumazenil binding after epilepsy surgery
Savic I; Blomqvist G; Halldin C; Litton JE; Gulyas B
Article: HUMAN BRAIN MAPPING. 1998;6(3):115-127
Visual form discrimination from texture cues: A PET study
Gulyas B; Cowey A; Heywood CA; Popplewell D; Roland PE
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1996;8(11):2232-2235
Assumptions and validations of statistical tests for functional neuroimaging
Roland PE; Gulyas B
Article: NEUROREPORT. 1996;7(2):463-468
Cortical representation of self-paced finger movement
Larsson J; Gulyas B; Roland PE
Article: SCIENCE. 1996;271(5248):512-515
Activation by attention of the human reticular formation and thalamic intralaminar nuclei
Kinomura S; Larsson J; Gulyas B; Roland PE
Article: BIOLOGIA FUTURA. 1996;47(1-4):157-172
Regional glucose metabolic rates in the human brain:: A PET study
Gulyás B; Trón L; Balkay L; Emri M; Molnár T; Tóth G; Marian T
Article: HUMAN BRAIN MAPPING. 1995;3(2):133-152
Cortical fields participating in spatial frequency and orientation discrimination functional anatomy by positron emission tomography
Gulyas B; Roland PE
Article: CEREBRAL CORTEX. 1995;5(1):79-93
VISUAL MEMORY, VISUAL-IMAGERY, AND VISUAL RECOGNITION OF LARGE FIELD PATTERNS BY THE HUMAN BRAIN - FUNCTIONAL-ANATOMY BY POSITRON EMISSION TOMOGRAPHY
ROLAND PE; GULYAS B
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Professor Emeritus/Emerita, Department of Clinical Neuroscience, Karolinska Institutet, 2025-2027
Professor, Department of Clinical Neuroscience, Karolinska Institutet, 2011-2024

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Docent, Karolinska Institutet, 1997

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