Miguel Cortes Gonzalez

Publications
Public outreach and news

Articles

Journal article: ACS CHEMICAL NEUROSCIENCE. 2024
Identification and In Vitro and In Vivo Characterization of KAC-50.1 as a Potential α-Synuclein PET Radioligand.
Saturnino Guarino D; Miranda Azpiazu P; Sunnemark D; Elmore CS; Bergare J; Artelsmair M; Nordvall G; Forsberg Morén A; Jia Z; Cortes-Gonzalez M; Mach R; Wilcox KC; Finnema S; Schou M; Varrone A
Article: JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS. 2024;67(6):245-249
Validation of a good manufacturing practice procedure for the production of [¹¹C]AZD4747, a CNS penetrant KRAS^G12c inhibitor
Gonzalez MAC; Hognasbacka AA; Halldin C; Schou M
Article: CLINICAL CANCER RESEARCH. 2024;30(7):1338-1351
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1
Staniszewska AD; Pilger D; Gill SJ; Jamal K; Bohin N; Guzzetti S; Gordon J; Hamm G; Mundin G; Illuzzi G; Pike A; McWilliams L; Maglennon G; Rose J; Hawthorne G; Gonzalez MC; Halldin C; Johnstroem P; Schou M; Critchlow SE; Fawell S; Johannes JW; Leo E; Davies BR; Cosulich S; Sarkaria JN; O'Connor MJ; Hamerlik P
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2023;66(13):9147-9160
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS^G12C with Demonstrable CNS Penetration
Kettle JG; Bagal SK; Barratt D; Bodnarchuk MS; Boyd S; Braybrooke E; Breed J; Cassar DJ; Cosulich S; Davies M; Davies NL; Deng C; Eatherton A; Evans L; Feron LJ; Fillery S; Gleave ES; Goldberg FW; Gonzalez MAC; Guerot C; Haider A; Harlfinger S; Howells R; Jackson A; Johnstrom P; Kemmitt PD; Koers A; Kondrashov M; Lamont GM; Lamont S; Lewis HJ; Liu L; Mylrea M; Nash S; Niedbala MJ; Peter A; Phillips C; Pike K; Raubo P; Robb GR; Ross S; Sanders MG; Schou M; Simpson I; Steward O
Article: JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS. 2022;65(10-11):288-291
Simplified and accessible [¹⁸F]F-AraG synthesis procedure for preclinical PET
Hognasbacka AA; Gonzalez MAC; Halldin C; Schou M
Journal article: CHEMICAL COMMUNICATIONS. 2021;57(68):8476-8479
Base-catalysed ¹⁸F-labelling of trifluoromethyl ketones. Application to the synthesis of ¹⁸F-labelled neutrophil elastase inhibitors
Meyer DN; Cortes Gonzalez MA; Jiang X; Johansson-Holm L; Pourghasemi Lati M; Elgland M; Nordeman P; Antoni G; Szabo KJ
Journal article: JOURNAL OF ORGANIC CHEMISTRY. 2020;85(13):8311-8319
Trifluoromethylthiolation, Trifluoromethylation, and Arylation Reactions of Difluoro Enol Silyl Ethers
Jiang X; Meyer D; Baran D; Cortes Gonzalez MA; Szabo KJ
Journal article: CHEMICAL COMMUNICATIONS. 2019;55(89):13358-13361
Rhodium-mediated ¹⁸F-oxyfluorination of diazoketones using a fluorine-18-containing hypervalent iodine reagent
Gonzalez MAC; Jiang X; Nordeman P; Antoni G; Szabo KJ
Article: CHEMICAL COMMUNICATIONS. 2018;54(34):4286-4289
[¹⁸F]fluoro-benziodoxole: a no-carrier-added electrophilic fluorinating reagent. Rapid, simple radiosynthesis, purification and application for fluorine-18 labelling
Gonzalez MAC; Nordeman P; Gomez AB; Meyer DN; Antoni G; Schou M; Szabo KJ
Article: JOURNAL OF FLUORINE CHEMISTRY. 2017;194:51-57
Synthesis of trifluoromethyl moieties by late-stage copper (I) mediated nucleophilic fluorination
Gome AB; Gonzalez MAC; Lubcke M; Johansson MJ; Schou M; Szabo KJ
Article: CHEMICAL COMMUNICATIONS. 2016;52(97):13963-13966
Efficient DBU accelerated synthesis of ¹⁸F-labelled trifluoroacetamides
Gomez AB; Gonzalez MAC; Lubcke M; Johansson MJ; Halldin C; Szabo KJ; Schou M
Journal article: ACS CATALYSIS. 2016;6(1):447-450
Palladium-Catalyzed lodofluorination of Alkenes Using Fluorolodoxole Reagent
Ilchenko NO; Cortes MA; Szabo KJ

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Thesis / dissertation: 2019
Development of new Fluorination Methods Directed to Fluorine-18 Labelling
Cortes Gonzalez M

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