Gerald McInerney Group
Regulation of Gene Expression during Viral Infection
All viruses, regardless of their host tropism, genome structure or any other properties, must use components of the host cell gene expression machinery in order to propagate. This reliance has led to the development of an evolutionary arms-race between viruses and hosts. Viral strategies have evolved to ensure access to this machinery while host cells have developed means to recognize viruses as foreign entities and to restrict their expression. In turn, viruses have developed methods to counteract these restrictions and to reduce the cells ability to communicate with its neighbouring cells. Our work concerns the mechanisms of regulation of gene expression during the early stages of viral infections. Using Semliki Forest virus as a model, we are studying viral interactions with diverse cellular pathways and systems including the translation machinery, the type I interferon system and protein degradation systems.
Read more about our group activities at alphavirus.org
Group Members
![]() | Benjamin Götte | Doktorand, Forskarstuderande | |
![]() | Leo Hanke | Anknuten | |
![]() | Peter Liljeström | Professor, senior | |
![]() | Lifeng Liu | Doktorand, Forskarstuderande | |
![]() | Karl Ljungberg | Senior lab manager | |
![]() | Gerald McInerney | Forskare | |
![]() | Ainhoa Moliner Morro | Doktorand, Forskarstuderande | |
![]() | Marc Panas | Anknuten | |
Lina Poulain | Anknuten | ||
![]() | Inga Szurgot | Postdoc | |
Timothy Tan | Anknuten | ||
Eline van Huizen | Anknuten |
Former Group Members
Post Doc Bastian Thaa
Post Doc Roberta Biasiotto
PhD Student Kai Eng
Post Doc Thomas Kuri
Selected Publications
Further Publications