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Gerald McInerney Group

Regulation of Gene Expression during Viral Infection

All viruses, regardless of their host tropism, genome structure or any other properties, must use components of the host cell gene expression machinery in order to propagate. This reliance has led to the development of an evolutionary arms-race between viruses and hosts. Viral strategies have evolved to ensure access to this machinery while host cells have developed means to recognize viruses as foreign entities and to restrict their expression. In turn, viruses have developed methods to counteract these restrictions and to reduce the cells ability to communicate with its neighbouring cells. Our work concerns the mechanisms of regulation of gene expression during the early stages of viral infections. Using Semliki Forest virus as a model, we are studying viral interactions with diverse cellular pathways and systems including the translation machinery, the type I interferon system and protein degradation systems.

Read more about our group activities at alphavirus.org

Group Members

Benjamin GötteDoktorand, Forskarstuderande

benjamin.gotte@ki.se

Leo HankeAnknuten

leo.hanke@ki.se

Peter LiljeströmProfessor, senior

Peter.Liljestrom@ki.se

Lifeng LiuDoktorand, Forskarstuderande

lifeng.liu@ki.se

Karl LjungbergSenior lab manager

karl.ljungberg@ki.se

Gerald McInerneyForskare

Gerald.McInerney@ki.se

08-524 869 51

Ainhoa Moliner MorroDoktorand, Forskarstuderande

ainhoa.moliner.morro@ki.se

Marc PanasAnknuten

marc.panas@ki.se

762258603

Lina PoulainAnknuten

lina.poulain@ki.se

Inga SzurgotPostdoc

inga.szurgot@ki.se

Timothy TanAnknuten

timothy.tan@ki.se

Eline van HuizenAnknuten

eline.van.huizen@ki.se

Former Group Members

Post Doc Bastian Thaa

Post Doc Roberta Biasiotto

PhD Student Kai Eng

Post Doc Thomas Kuri

Selected Publications

29377936

28968805

27535052

27383630

27022092

26339054

26101899

25896634

25658430

25605905

25211080

24623412

23087212

22438538

20458170

17553895

17553895

15930128

Further Publications

Further Publications on PubMed