Gerald Mc Inerney

About me
Publications
CV
Public outreach and news

Research

The McInerney research group at MTC are interested in early interactions between viruses and their host cells. Using alphaviruses as model systems, we are exploring the role(s) of cellular processes such as stress responses, the interferon system and autophagy in viral infection. More information on our group website.

Since 2020, we have been developing SARS-CoV-2 neutralising nanobodies as part of the CoroNAb consortium.

Teaching

I am involved in teaching at several levels at KI:
- Summer Research School with Biomedical Orientation for Gymnasium (High
School) Students
- Immunology and Microbiology course for undergraduate students in
Biomedicine
- Degree Project course for undergraduate students in Biomedicine

Articles

Article: NATURE COMMUNICATIONS. 2024;15(1):10607
SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs
Long S; Guzyk M; Vidakovics LP; Han X; Sun R; Wang M; Panas MD; Urgard E; Coquet JM; Merits A; Achour A; Mcinerney GM
Article: NUCLEIC ACIDS RESEARCH. 2024;52(16):9745-9759
Stress granule formation helps to mitigate neurodegeneration
Glineburg MR; Yildirim E; Gomez N; Rodriguez G; Pak J; Li X; Altheim C; Waksmacki J; McInerney GM; Barmada SJ; Todd PK
Article: NATURE COMMUNICATIONS. 2024;15(1):6338
Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques
Mandolesi M; Das H; de Vries L; Yang Y; Kim C; Dhinakaran M; Castro Dopico X; Fischbach J; Kim S; Guryleva MV; Adori M; Chernyshev M; Stalmarck A; Hanke L; Mcinerney GM; Sheward DJ; Corcoran M; Haellberg BM; Murrell B; Karlsson Hedestam GB
Article: CELL REPORTS MEDICINE. 2024;5(6):101577
Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies
Sheward DJ; Pushparaj P; Das H; Greaney AJ; Kim C; Kim S; Hanke L; Hyllner E; Dyrdak R; Lee J; Dopico XC; Dosenovic P; Peacock TP; McInerney GM; Albert J; Corcoran M; Bloom JD; Murrell B; Hedestam GBK; Hallberg BM
Article: JCI INSIGHT. 2023;8(17):e167656
Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations
Zhang J; Koolmeister C; Han J; Filograna R; Hanke L; Adori M; Sheward DJ; Teifel S; Gopalakrishna S; Shao Q; Liu Y; Zhu K; Harris RA; Mcinerney G; Murrell B; Aoun M; Baeckdahl L; Holmdahl R; Pekalski M; Wedell A; Engvall M; Wredenberg A; Hedestam GBK; Dopico XC; Rorbach J
Article: NANO LETTERS. 2023;23(9):3701-3707
A Multiparametric and High-Throughput Platform for Host-Virus Binding Screens
Schlegel J; Porebski B; Andronico L; Hanke L; Edwards S; Brismar H; Murrell B; McInerney GM; Fernandez-Capetillo O; Sezgin E
Article: OPEN BIOLOGY. 2023;13(5):220369
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH
Schulte T; Panas MD; Han X; Williams L; Kedersha N; Fleck JS; Tan TJC; Dopico XC; Olsson A; Morro AM; Hanke L; Nilvebrant J; Giang KA; Nygren P-A; Anderson P; Achour A; McInerney GM
Article: EUROSURVEILLANCE. 2023;28(13):2200432
At-home sampling to meet geographical challenges for serological assessment of SARS-CoV-2 exposure in a rural region of northern Sweden, March to May 2021: a retrospective cohort study
Bystrom JW; Vikstrom L; Rosendal E; Groning R; Gwon Y-D; Nilsson E; Sharma A; Espaillat A; Hanke L; McInerney G; Puhar A; Cava F; Hedestam GBK; Thunberg T; Monsen T; Elgh F; Evander M; Johansson AF; Overby AK; Ahim C; Normark J; Forsell MNE
Article: IMMUNITY. 2023;56(1):193-206.e7
Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies
Pushparaj P; Nicoletto A; Sheward DJ; Das H; Dopico XC; Vidakovics LP; Hanke L; Chernyshev M; Narang S; Kim S; Fischbach J; Ekstrom S; McInerney G; Hallberg BM; Murrell B; Corcoran M; Hedestam GBK
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:941281
SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses
Christensen D; Polacek C; Sheward DJ; Hanke L; McInerney G; Murrell B; Hartmann KT; Jensen HE; Zimmermann J; Jungersen G; Illigen KE; Isling LK; Fernandez-Antunez C; Ramirez S; Bukh J; Pedersen GK
Article: VIROLOGY. 2022;577:1-15
Multi-target direct-acting SARS-CoV-2 antivirals against the nucleotide-binding pockets of virus-specific proteins
Rani R; Long S; Pareek A; Dhaka P; Singh A; Kumar P; McInerney G; Tomar S
Article: EBIOMEDICINE. 2022;84:104248
Protection against SARS-CoV-2 transmission by a parenteral prime-Intranasal boost vaccine strategy
Christensen D; Polacek C; Sheward DJ; Hanke L; Moliner-Morro A; McInerney G; Murrell B; Hartmann KT; Jensen HE; Jungersen G; Illigen K; Isling LK; Jensen RF; Hansen JS; Rosenkrands I; Fernandez-Antunez C; Ramirez S; Follmann F; Bukh J; Pedersen GK
Article: PLOS PATHOGENS. 2022;18(9):e1010743
Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes
Yang E; Huang S; Jami-Alahmadi Y; McInerney GM; Wohlschlegel JA; Li MMH
Article: SCIENCE ADVANCES. 2022;8(12):eabm0220
Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies
Hanke L; Sheward DJ; Pankow A; Vidakovics LP; Karl V; Kim C; Urgard E; Smith NL; Astorga-Wells J; Ekstrom S; Coquet JM; McInerney GM; Murrell B
Article: NATURE COMMUNICATIONS. 2022;13(1):155
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo
Hanke L; Das H; Sheward DJ; Vidakovics LP; Urgard E; Moliner-Morro A; Kim C; Karl V; Pankow A; Smith NL; Porebski B; Fernandez-Capetillo O; Sezgin E; Pedersen GK; Coquet JM; Hallberg BM; Murrell B; McInerney GM
Article: NANO SELECT. 2022;3(1):227-232
Colloidal dispersion of poly(ionic liquid)/Cu composite particles for protective surface coating against SAR-CoV-2
Kheirabad AK; Pan X; Long S; Kochovski Z; Zhou S; Lu Y; McInerney G; Yuan J
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2022;11(3):e1379
Probabilistic classification of anti-SARS-CoV-2 antibody responses improves seroprevalence estimates
Dopico XC; Muschiol S; Grinberg NF; Aleman S; Sheward DJ; Hanke L; Ahl M; Vikstrom L; Forsell M; Coquet JM; McInerney G; Dillner J; Bogdanovic G; Murrell B; Albert J; Wallace C; Hedestam GBK
Article: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 2022;10:1083232
Silver nanoparticles with excellent biocompatibility block pseudotyped SARS-CoV-2 in the presence of lung surfactant
Gupta G; Hamawandi B; Sheward DJ; Murrell B; Hanke L; McInerney G; Blosi M; Costa AL; Toprak MS; Fadeel B
Article: NATURE COMMUNICATIONS. 2021;12(1):6761
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
Kruse T; Benz C; Garvanska DH; Lindqvist R; Mihalic F; Coscia F; Inturi R; Sayadi A; Simonetti L; Nilsson E; Ali M; Kliche J; Morro AM; Mund A; Andersson E; McInerney G; Mann M; Jemth P; Davey NE; Overby AK; Nilsson J; Ivarsson Y
Article: CELL REPORTS MEDICINE. 2021;2(11):100450
Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models
Sheward DJ; Mandolesi M; Urgard E; Kim C; Hanke L; Vidakovics LP; Pankow A; Smith NL; Dopico XC; McInerney GM; Coquet JM; Hedestam GBK; Murrell B
Article: JOURNAL OF INTERNAL MEDICINE. 2021;290(3):666-676
Seropositivity in blood donors and pregnant women during the first year of SARS-CoV-2 transmission in Stockholm, Sweden
Castro Dopico X; Muschiol S; Christian M; Hanke L; Sheward DJ; Grinberg NF; Rorbach J; Bogdanovic G; Mcinerney GM; Allander T; Wallace C; Murrell B; Albert J; Karlsson Hedestam GB
Article: NATURE COMMUNICATIONS. 2021;12(1):3695
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2
Roxhed N; Bendes A; Dale M; Mattsson C; Hanke L; Dodig-Crnkovic T; Christian M; Meineke B; Elsasser S; Andrell J; Havervall S; Thalin C; Eklund C; Dillner J; Beck O; Thomas CE; McInerney G; Hong M-G; Murrell B; Fredolini C; Schwenk JM
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(12):6287
Arabidopsis thaliana G3BP Ortholog Rescues Mammalian Stress Granule Phenotype across Kingdoms
Reuper H; Goette B; Williams L; Tan TJC; McInerney GM; Panas MD; Krenz B
Article: NANOMATERIALS. 2021;11(5):1312
Antiviral Activity of Silver, Copper Oxide and Zinc Oxide Nanoparticle Coatings against SARS-CoV-2
Merkl P; Long S; McInerney GM; Sotiriou GA
Article: CELL REPORTS MEDICINE. 2021;2(4):100252
SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses
Mandolesi M; Sheward DJ; Hanke L; Ma J; Pushparaj P; Vidakovics LP; Kim C; Adori M; Lenart K; Lore K; Dopico XC; Coquet JM; McInerney GM; Hedestam GBK; Murrell B
Article: SCIENTIFIC REPORTS. 2021;11(1):3125
DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice
Szurgot I; Hanke L; Sheward DJ; Vidakovics LP; Murrell B; McInerney GM; Liljestrom P
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1312
Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay
Hober S; Hellstrom C; Olofsson J; Andersson E; Bergstrom S; Jernbom Falk A; Bayati S; Mravinacova S; Sjoberg R; Yousef J; Skoglund L; Kanje S; Berling A; Svensson A-S; Jensen G; Enstedt H; Afshari D; Xu LL; Zwahlen M; von Feilitzen K; Hanke L; Murrell B; McInerney G; Karlsson Hedestam GB; Lendel C; Roth RG; Skoog I; Svenungsson E; Olsson T; Fogdell-Hahn A; Lindroth Y; Lundgren M; Maleki KT; Lagerqvist N; Klingstrom J; Da Silva Rodrigues R; Muschiol S; Bogdanovic G; Arroyo Muhr LS; Eklund C; Lagheden C; Dillner J; Sivertsson A; Havervall S; Thalin C; Tegel H; Pin E; Manberg A; Hedhammar M; Nilsson P
Article: EBIOMEDICINE. 2021;63:103197
Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice
Worzner K; Sheward DJ; Schmidt ST; Hanke L; Zimmermann J; McInerney G; Hedestam GBK; Murrell B; Christensen D; Pedersen GK
Article: BIOMOLECULES. 2020;10(12):E1661-1661
Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs
Moliner-Morro A; J. Sheward D; Karl V; Perez Vidakovics L; Murrell B; McInerney GM; Hanke L
Article: NATURE COMMUNICATIONS. 2020;11(1):5588
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
Custodio TF; Das H; Sheward DJ; Hanke L; Pazicky S; Pieprzyk J; Sorgenfrei M; Schroer MA; Gruzinov AY; Jeffries CM; Graewert MA; Svergun DI; Dobrev N; Remans K; Seeger MA; McInerney GM; Murrell B; Haellberg BM; Loew C
Article: NATURE COMMUNICATIONS. 2020;11(1):5064
SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
Rudberg A-S; Havervall S; Manberg A; Jernbom Falk A; Aguilera K; Ng H; Gabrielsson L; Salomonsson A-C; Hanke L; Murrell B; McInerney G; Olofsson J; Andersson E; Hellstrom C; Bayati S; Bergstrom S; Pin E; Sjoberg R; Tegel H; Hedhammar M; Phillipson M; Nilsson P; Hober S; Thalin C
Article: JOURNAL OF VIROLOGY. 2020;94(7):e01681-e01619
Sensitivity of Alphaviruses to G3BP Deletion Correlates with Efficiency of Replicase Polyprotein Processing
Gotte B; Utt A; Fragkoudis R; Merits A; McInerney GM
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2020;10:537782
Replication of Salmonella enterica serovar Typhimurium in RAW264.7 Phagocytes Correlates With Hypoxia and Lack of iNOS Expression
Wrande M; Vesto K; Banesaru SP; Anwar N; Nordfjell J; Liu L; McInerney GM; Rhen M
Article: JOURNAL OF GENERAL VIROLOGY. 2019;100(10):1375-1389
RNA processing bodies are disassembled during Old World alphavirus infection
Liu L; Weiss E; Panas MD; Gotte B; Sellberg S; Thaa B; McInerney GM
Article: ELIFE. 2019;8:e46681
Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
Hosmillo M; Lu J; McAllaster MR; Eaglesham JB; Wang X; Emmott E; Domingues P; Chaudhry Y; Fitzmaurice TJ; Tung MKH; Panas MD; McInerney G; Locker N; Wilen CB; Goodfellow IG
Article: VIRUSES-BASEL. 2018;10(5):E226-226
Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus
Mutso M; Morro AM; Smedberg C; Kasvandik S; Aquilimeba M; Teppor M; Tarve L; Lulla A; Lulla V; Saul S; Thaa B; McInerney GM; Merits A; Varjak M
Article: PLOS ONE. 2018;13(4):e0195956
Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib
Ladds MJGW; Pastor-Fernandez A; Popova G; van Leeuwen IMM; Eng KE; Drummond CJ; Johansson L; Svensson R; Westwood NJ; McCarthy AR; Tholander F; Popa M; Lane DP; McCormack E; McInerney GM; Bhatia R; Lain S
Article: JOURNAL OF INFECTIOUS DISEASES. 2017;216(10):1308-1317
A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense
Svedin E; Utorova R; Huhn MH; Larsson PG; Stone VM; Garimella M; Lind K; Hagglof T; Pincikova T; Laitinen OH; McInerney GM; Scholte B; Hjelte L; Karlsson MCI; Flodstrom-Tullberg M
Article: CHEMMEDCHEM. 2017;12(8):613-620
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
Hardes K; Ivanova T; Thaa B; McInerney GM; Klokk TI; Sandvig K; Kuenzel S; Lindberg I; Steinmetzer T
Article: JOURNAL OF VIROLOGY. 2016;90(21):9743-9757
The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling
Varghese FS; Thaa B; Amrun SN; Simarmata D; Rausalu K; Nyman TA; Merits A; McInerney GM; Ng LFP; Ahola T
Article: JOURNAL OF VIROLOGY. 2016;90(8):4150-4159
Effects of an In-Frame Deletion of the 6k Gene Locus from the Genome of Ross River Virus
Taylor A; Melton JV; Herrero LJ; Thaa B; Karo-Astover L; Gage PW; Nelson MA; Sheng K-C; Lidbury BA; Ewart GD; McInerney GM; Merits A; Mahalingam S
Article: JOURNAL OF CELL BIOLOGY. 2016;212(7):845-860
G3BP-Caprin 1-USP10 complexes mediate stress granule condensation and associate with 40S subunits
Kedersha N; Panas MD; Achorn CA; Lyons S; Tisdale S; Hickman T; Thomas M; Lieberman J; McInerney GM; Ivanov P; Anderson P
Article: PLOS ONE. 2016;11(6):e0157435
A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles
Gullberg M; Lohse L; Botner A; McInerney GM; Burman A; Jackson T; Polacek C; Belsham GJ
Article: JOURNAL OF VIROLOGY. 2015;89(22):11420-11437
Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization
Thaa B; Biasiotto R; Eng K; Neuvonen M; Gotte B; Rheinemann L; Mutso M; Utt A; Varghese F; Balistreri G; Merits A; Ahola T; McInerney GM
Article: DNA AND CELL BIOLOGY. 2015;34(9):557-560
FGDF Motif Regulation of Stress Granule Formation
McInerney GM
Article: JOURNAL OF IMMUNOLOGY. 2015;194(9):4422-4430
Protection of Human Myeloid Dendritic Cell Subsets against Influenza A Virus Infection Is Differentially Regulated upon TLR Stimulation
Baharom F; Thomas S; Bieder A; Hellmer M; Volz J; Sandgren KJ; McInerney GM; Hedestam GBK; Mellman I; Smed-Sorensen A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(5):E440-E449
Real-time resolution of point mutations that cause phenovariance in mice
Wang T; Zhan X; Bu C-H; Lyon S; Pratt D; Hildebrand S; Choi JH; Zhang Z; Zeng M; Wang K-W; Turer E; Chen Z; Zhang D; Yue T; Wang Y; Shi H; Wang J; Sun L; SoRelle J; McAlpine W; Hutchins N; Zhan X; Fina M; Gobert R; Quan J; Kreutzer M; Arnett S; Hawkins K; Leach A; Tate C; Daniel C; Reyna C; Prince L; Davis S; Purrington J; Bearden R; Weatherly J; White D; Russell J; Sun Q; Tang M; Li X; Scott L; Moresco EMY; McInerney GM; Hedestam GBK; Xie Y; Beutler B
Journal article: SCIENCE. 2014;346(6216):1486-1492
MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses (Retracted Article)
Zeng M; Hu Z; Shi X; Li X; Zhan X; Li X-D; Wang J; Choi JH; Wang K-W; Purrington T; Tang M; Fina M; DeBerardinis RJ; Moresco EMY; Pedersen G; McInerney GM; Hedestam GBK; Chen ZJ; Beutler B
Article: CELL HOST & MICROBE. 2014;16(3):403-411
The Host Nonsense-Mediated mRNA Decay Pathway Restricts Mammalian RNA Virus Replication
Balistreri G; Horvath P; Schweingruber C; Zuend D; McInerney G; Merits A; Muehlemann O; Azzalin C; Helenius A
Article: JOURNAL OF VIROLOGY. 2014;88(10):5888-5893
The C-Terminal Repeat Domains of nsP3 from the Old World Alphaviruses Bind Directly to G3BP
Panas MD; Ahola T; McInerney GM
Article: CELLULAR MICROBIOLOGY. 2013;15(8):1385-1400
Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected with Streptococcus pneumoniae
Kuri T; Sorensen AS; Thomas S; Hedestam GBK; Normark S; Henriques-Normark B; McInerney GM; Plant L
Article: MOLECULAR BIOLOGY OF THE CELL. 2012;23(24):4701-4712
Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection
Panas MD; Varjak M; Lulla A; Eng KE; Merits A; Hedestam GBK; McInerney GM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(31):12286-12293
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity
Arnold CN; Pirie E; Dosenovic P; McInerney GM; Xia Y; Wang N; Li X; Siggs OM; Hedestam GBK; Beutler B
Article: JOURNAL OF VIROLOGY. 2012;86(10):5674-5685
Accumulation of Autophagosomes in Semliki Forest Virus-Infected Cells Is Dependent on Expression of the Viral Glycoproteins
Eng KE; Panas MD; Murphy D; Hedestam GBK; McInerney GM
Article: PLOS PATHOGENS. 2012;8(5):e1002670
Age-Dependent TLR3 Expression of the Intestinal Epithelium Contributes to Rotavirus Susceptibility
Pott J; Stockinger S; Torow N; Smoczek A; Lindner C; McInerney G; Backhed F; Baumann U; Pabst O; Bleich A; Hornef MW
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(18):7499-7504
Adenovirus type-35 vectors block human CD4⁺ T-cell activation via CD46 ligation
Adams WC; Gujer C; McInerney G; Gall JGD; Petrovas C; Hedestam GBK; Koup RA; Lore K
Article: PLOS ONE. 2011;6(12):e29523
Multiple Polymorphisms Affect Expression and Function of the Neuropeptide S Receptor (NPSR1)
Anedda F; Zucchelli M; Schepis D; Hellquist A; Corrado L; D'Alfonso S; Achour A; McInerney G; Bertorello A; Lordal M; Befrits R; Bjork J; Bresso F; Torkvist L; Halfvarson J; Kere J; D'Amato M
Article: AUTOPHAGY. 2010;6(5):634-641
A novel quantitative flow cytometry-based assay for autophagy
Eng KE; Panas MD; Hedestam GBK; McInerney GM
Article: PLOS PATHOGENS. 2010;6(4):e1000866
A Differential Role for Macropinocytosis in Mediating Entry of the Two Forms of Vaccinia Virus into Dendritic Cells
Sandgren KJ; Wilkinson J; Miranda-Saksena M; McInerney GM; Byth-Wilson K; Robinson PJ; Cunningham AL
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(7):3046-3051
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
Siggs OM; Berger M; Krebs P; Arnold CN; Eidenschenk C; Huber C; Pirie E; Smart NG; Khovananth K; Xia Y; McInerney G; Hedestam GBK; Nemazee D; Beutler B
Article: NUCLEIC ACIDS RESEARCH. 2008;36(16):e99
Specific ligation to double-stranded RNA for analysis of cellular RNA::RNA interactions
Faridani OR; McInerney GM; Gradin K; Good L
Article: JOURNAL OF GENERAL VIROLOGY. 2007;88(Pt 10):2774-2779
Increased human immunodeficiency virus type 1 Env expression and antibody induction using an enhanced alphavirus vector
Forsell MNE; McInerney GM; Dosenovic P; Hidmark AS; Eriksson C; Liljestorm P; Grundner C; Hedestam GBK
Article: JOURNAL OF VIROLOGY. 2007;81(16):8677-8684
Semliki forest virus nonstructural protein 2 is involved in suppression of the type I interferon response
Breakwell L; Dosenovic P; Hedestam GBK; D'Amato M; Liljestrom P; Fazakerley J; McInerney GM
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2007;65(6):494-502
Bone marrow dendritic cells internalize live RF-81 bovine rotavirus and rotavirus-like particles (RF 2/6-GFP-VLP and RF 8*2/6/7-VLP) but are only activated by live bovine rotavirus
Istrate C; Douagi I; Charpilienne A; McInerney GM; Hidmark A; Johansen K; Larsson M; Magnusson K-E; Poncet D; Svensson L; Hinkula J
Article: JOURNAL OF VIROLOGY. 2007;81(6):2758-2768
Role of interferon regulatory factor 3 in type I interferon responses in rotavirus-infected dendritic cells and fibroblasts
Douagi I; McInerney GA; Hidmark AS; Miriallis V; Johansen K; Svensson L; Hedestam GBK
Article: VIROLOGY. 2005;341(2):190-202
Efficient expansion of HIV-1-specific T cell responses by homologous immunization with recombinant Semliki Forest virus particles
Sundbäck M; Douagi I; Dayaraj C; Forsell MNE; Nordström EKL; McInerney GM; Spångberg K; Tjäder L; Bonin E; Sundström M; Liljeström P; Hedestam GBK
Article: JOURNAL OF VIROLOGY. 2005;79(16):10376-10385
Early alpha/beta interferon production by myeloid dendritic cells in response to UV-inactivated virus requires viral entry and interferon regulatory factor 3 but not MyD88
Hidmark Å; McInerney GM; Nordström EKL; Douagi I; Werner KM; Liljeström P; Hedestam GBK
Article: MOLECULAR BIOLOGY OF THE CELL. 2005;16(8):3753-3763
Importance of eIF2α phosphorylation assembly in alphavirus translation and stress granule regulation
McInerney GM; Kedersha NL; Kaufman RJ; Anderson P; Liljeström P
Article: JOURNAL OF VIROLOGY. 2005;79(12):7942-7948
Reversible acid-induced inactivation of the membrane fusion protein of Semliki Forest virus
Waarts BL; Smit JM; Aneke OJC; McInerney GM; Liljeström P; Bittman R; Wilschut J
Article: VIROLOGY. 2004;325(2):200-206
Semliki Forest virus produced in the absence of the 6K protein has an altered spike structure as revealed by decreased membrane fusion capacity
McInerney GM; Smit JM; Liljeström P; Wilschut J
Article: JOURNAL OF GENERAL VIROLOGY. 2000;81(Pt 7):1699-1702
Replication-competent foot-and-mouth disease virus RNAs lacking capsid ceding sequences
McInerney GM; King AMQ; Ross-Smith N; Belsham GJ
Article: JOURNAL OF VIROLOGY. 2000;74(1):272-280
Foot-and-mouth disease virus 3C protease induces cleavage of translation initiation factors eIF4A and eIF4G within infected cells
Belsham GJ; McInerney GM; Ross-Smith N
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Professor, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2021-

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Docent, Karolinska Institutet, 2013

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