Research group Peder Olofsson
We study cellular and molecular mechanisms of cardiovascular and inflammatory diseases with the aim to contribute building blocks for improved therapy and better outcomes.
Pathophysiological mechanisms of cardiovascular and inflammatory diseases
Overactive inflammation causes increased morbidity and mortality, not least in cardiovascular disease, the most common cause of death in the world.
By combining studies of molecular mechanisms in model systems and large-scale analysis (omics) of our own clinical cohorts, we aim to elucidate the mechanisms behind cardiovascular and inflammatory diseases. A better understanding of the physiological mechanisms that drive disease development promises better opportunities for treatment and prevention.
Teams
The disease mechanisms are complex and in the group there are six teams that work together with complementary perspectives to study inflammation and blood vessel biology.
- Team Björck: Molecular and epidemiological studies of ascending aortic aneurysms.
- Team Gigante
- Team Gisterå: Immunology of atherosclerosis
- Team Li: Atherothrombosis Research
- Team Maegdefessel
- Team Olofsson: Neural regulation of inflammation and metabolism.
(Links to the teams are added as the pages are created. For contact information for the team leaders, please use the search function at the top of this page.)
Detailed cellular and molecular characterization can provide important insights into physiological mechanisms (www.proteinatlas.org).