Alzheimer’s Disease Risk Factors & Sex-Specific Mechanisms – Silvia Maioli's research group

Alzheimer’s disease (AD) results from a complex interaction of genetic, environmental, and age-related factors. Our research focuses on the interplay between biological sex (female vs. male) and cholesterol-related environmental and genetic risk factors (hypercholesterolemia, APOE4 genotype), using mouse models and human clinical and postmortem samples. By identifying sex-specific pathways that drive disease progression, we aim to develop tailored strategies for AD prevention and treatment.

Patri1

Latest news from our research group

Keywords:
Aging Alzheimer Disease Apolipoprotein E4 Cell and Molecular Biology Cholesterol Cholesterol 24-Hydroxylase Geriatrics Memory Neurosciences Oxysterols Polypharmacy Risk Factors Women's Health Show all
Content reviewer:
21-03-2025