Julen Goicolea

Publications
CV
Public outreach and news

Articles

Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2024;119:286-300
Dynamic microglia alterations associate with hippocampal network impairments: A turning point in amyloid pathology progression
Pizzirusso G; Preka E; Goikolea J; Aguilar-Ruiz C; Rodriguez-Rodriguez P; Vazquez-Cabrera G; Laterza S; Latorre-Leal M; Eroli F; Blomgren K; Maioli S; Nilsson P; Fragkopoulou A; Fisahn A; Arroyo-Garcia LE
Article: FRONTIERS IN CELLULAR NEUROSCIENCE. 2024;18:1347535
Impaired astrocytic synaptic function by peripheral cholesterol metabolite 27-hydroxycholesterol
Spanos F; Gerenu G; Goikolea J; Latorre-Leal M; Balleza-Tapia H; Gomez K; Alvarez-Jimenez L; Piras A; Gomez-Galan M; Fisahn A; Cedazo-Minguez A; Maioli S; Loera-Valencia R
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2023;234:106387
Different effects of CYP27A1 and CYP7B1 on cognitive function: Two mouse models in comparison
Goikolea J; Latorre-Leal M; Tsagkogianni C; Pikkupeura S; Gulyas B; Cedazo-Minguez A; Loera-Valencia R; Bjorkhem I; Rodriguez PR; Maioli S
Article: BRAIN COMMUNICATIONS. 2023;5(5):fcad228
Alzheimer's disease biomarker profiling in a memory clinic cohort without common comorbidities
Daniilidou M; Eroli F; Alanko V; Goikolea J; Latorre-Leal M; Rodriguez-Rodriguez P; Griffiths WJ; Wang Y; Pacciarini M; Brinkmalm A; Zetterberg H; Blennow K; Rosenberg A; Bogdanovic N; Winblad B; Kivipelto M; Ibghi D; Cedazo-Minguez A; Maioli S; Matton A
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2022;14(1):37
Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer's disease: a potential early sign of AD
Goikolea J; Gerenu G; Daniilidou M; Mangialasche F; Mecocci P; Ngandu T; Rinne J; Solomon A; Kivipelto M; Cedazo-Minguez A; Sandebring-Matton A; Maioli S
Article: MOLECULAR NEUROBIOLOGY. 2021;58(12):6063-6076
Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration
Loera-Valencia R; Ismail M-A; Goikolea J; Lodeiro M; Mateos L; Bjorkhem I; Puerta E; Romao MA; Gomes CM; Merino-Serrais P; Maioli S; Cedazo-Minguez A
Article: MOLECULAR PSYCHIATRY. 2021;26(4):1410-1423
Thioredoxin-80 protects against amyloid-beta pathology through autophagic-lysosomal pathway regulation
Gerenu G; Persson T; Goikolea J; Calvo-Garrido J; Loera-Valencia R; Pottmeier P; Santiago C; Poska H; Presto J; Cedazo-Minguez A
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2021;13(1):56
27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial
Sandebring-Matton A; Goikolea J; Bjorkhem I; Paternain L; Kemppainen N; Laatikainen T; Ngandu T; Rinne J; Soininen H; Cedazo-Minguez A; Solomon A; Kivipelto M
Article: CELL DEATH AND DIFFERENTIATION. 2019;26(9):1545-1565
Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation
Guerrero-Gomez D; Antonio Mora-Lorca J; Saenz-Narciso B; Jose Naranjo-Galindo F; Munoz-Lobato F; Parrado-Fernandez C; Goikolea J; Cedazo-Minguez A; Link CD; Neri C; Dolores Sequedo M; Vazquez-Manrique RP; Fernandez-Suarez E; Goder V; Pane R; Cabiscol E; Askjaer P; Cabello J; Miranda-Vizuete A
Article: JOURNAL OF VIROLOGY. 2015;89(8):4645-4654
Triatoma virus recombinant VP4 protein induces membrane permeability through dynamic pores.
Sánchez-Eugenia R; Goikolea J; Gil-Cartón D; Sánchez-Magraner L; Guérin DMA

All other publications

Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:836196
Defects of Nutrient Signaling and Autophagy in Neurodegeneration
Ondaro J; Hernandez-Eguiazu H; Garciandia-Arcelus M; Loera-Valencia R; Rodriguez-Gomez L; Jimenez-Zuniga A; Goikolea J; Rodriguez-Rodriguez P; Ruiz-Martinez J; Moreno F; Lopez de Munain A; Holt IJ; Gil-Bea FJ; Gerenu G
Thesis / dissertation: 2021
Translational studies on Alzheimer’s disease : a focus on cholesterol metabolism, thioredoxin-80 and microglia function
Goicolea, Julen
Review: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2019;190:104-114
Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment
Loera-Valencia R; Goikolea J; Parrado-Fernandez C; Merino-Serraisa P; Maioli S

Employments

Affiliated to Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2024-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2022

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