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Publications | Nils-Göran Larsson Group

Find our latest publications as well as all publications by Principal Investigator Nils-Göran Larsson.

Recent original publications

Mutations of mitochondrial DNA are not major contributors to aging of fruit flies.
Kauppila TES, Bratic A, Jensen MB, Baggio F, Partridge L, Jasper H, et al
Proc. Natl. Acad. Sci. U.S.A. 2018 10;115(41):E9620-E9629

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice.
Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, et al
Nucleic Acids Res. 2018 Jul;46(13):6642-6669

PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly.
Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, et al
Cell Rep 2018 04;23(1):127-142

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.
Matic S, Jiang M, Nicholls TJ, Uhler JP, Dirksen-Schwanenland C, Polosa PL, et al
Nat Commun 2018 03;9(1):1202

Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.
Nicholls TJ, Nadalutti CA, Motori E, Sommerville EW, Gorman GS, Basu S, et al
Mol. Cell 2018 01;69(1):9-23.e6

LRPPRC-mediated folding of the mitochondrial transcriptome.
Siira SJ, Spåhr H, Shearwood AJ, Ruzzenente B, Larsson NG, Rackham O, et al
Nat Commun 2017 11;8(1):1532

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals.
Kühl I, Miranda M, Atanassov I, Kuznetsova I, Hinze Y, Mourier A, et al
Elife 2017 11;6():

Increased Total mtDNA Copy Number Cures Male Infertility Despite Unaltered mtDNA Mutation Load.
Jiang M, Kauppila TES, Motori E, Li X, Atanassov I, Folz-Donahue K, et al
Cell Metab. 2017 Aug;26(2):429-436.e4

Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila.
Brandt T, Mourier A, Tain LS, Partridge L, Larsson NG, Kühlbrandt W
Elife 2017 07;6():

Recent reviews

The Enigma of the Respiratory Chain Supercomplex.
Milenkovic D, Blaza JN, Larsson NG, Hirst J
Cell Metab. 2017 Apr;25(4):765-776

Mammalian Mitochondria and Aging: An Update.
Kauppila TES, Kauppila JHK, Larsson NG
Cell Metab. 2017 01;25(1):57-71

Maintenance and Expression of Mammalian Mitochondrial DNA.
Gustafsson CM, Falkenberg M, Larsson NG
Annu. Rev. Biochem. 2016 Jun;85():133-60

Keeping mtDNA in shape between generations.
Stewart JB, Larsson NG
PLoS Genet. 2014 Oct;10(10):e1004670

Making proteins in the powerhouse.
Hällberg BM, Larsson NG
Cell Metab. 2014 Aug;20(2):226-40

All publications by Nils-Göran Larsson

Publications by Nils-Göran Larsson on Pubmed