Nils-Göran Larsson
About me
I started my career as a clinically active physician and after completing my specialist degree in Paediatrics and my doctoral thesis at the University of Gothenburg, I continued as an HHMI Postdoctoral Fellow at Stanford University. Since 1997 I have been active at Karolinska Institutet and was Director at the Max Planck Institute for Biology of Ageing, Cologne, Germany from 2008 to 2015. My research area has always been focused on mitochondria and how impaired mitochondrial function causes disease in humans. I also have a strong interest in molecular regulation of mtDNA expression. Over the years, I have trained many researchers who have then gone on to independent careers. For further description, see my CV and profile page below.
More about me on my profile page: https://molmet.ki.se/nils-goran-larsson
Management experience:
Mitochondrial Medicine Center 2005-2008 KI Campus Syd
Director and Managing Director, Max Planck Institute for Biology of Ageing, Köln, Tyskland 2008-2015
Head of Department MBB 2016-2018
Vice Chairman/Chairman Nobel Committee for Physiology or Medicine 2019-2021.
Member of Konsistoriet 2022-2024.
Visions for my assignment in the board (Konsistoriet) of Karolinska Institutet,
My contribution will be based on my long national and international experience in basic and translational medical research. I also have experience in training doctors and extensive experience in supervising doctoral students. Karolinska Institutet's researchers have been very successful in attracting different types of external research funding. Unfortunately, this has led to an uncontrolled expansion with a large gap between the level of government funding, which is used for payment of teacher salaries, rents, IT fees, co-financing, etc., as well as available external research grants. The existing government appropriations (intramural resources) are insufficient in relation to the size of the activities. At present, various funding sources therefore have too much influence over recruitment and the focus of research at KI. It is clear that KI needs to review its size and consolidate its operations. The service structure for young researchers is also poorly defined and should be reviewed. In this context, it must be recalled that major discoveries are rarely the result of strategic initiatives, but often arise when researchers are given resources to process long-term scientific problems that typically lie outside the currently popular research directions. Major fundamental discoveries often lead to a number of new applications, and researchers at KI must therefore be given the conditions to deliver such important breakthroughs. I want to help accelerate these changes by contributing to a strategic vision in the Konsistorium.
Articles
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2024;52(18):11266-11282
- Journal article: NATURE AGING. 2024;:1
- Journal article: NATURE AGING. 2024;4(9):1174-1176
- Article: NATURE METABOLISM. 2024;6(6):1024-1035
- Article: NPJ PARKINSON'S DISEASE. 2024;10(1):93
- Article: LIFE SCIENCE ALLIANCE. 2024;7(2):e202302147
- Article: CELL METABOLISM. 2023;35(10):1799-1813.e7
- Article: PLOS GENETICS. 2023;19(1):e1010573
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2022;50(15):8749-8766
- Article: NATURE METABOLISM. 2022;4(6):651-662
- Article: PLOS GENETICS. 2022;18(5):e1010190
- Article: EMBO REPORTS. 2022;23(1):e53054
- Article: LIFE SCIENCE ALLIANCE. 2021;4(11):e202101034
- Article: PLOS GENETICS. 2021;17(9):e1009822
- Article: SCIENCE ADVANCES. 2021;7(27):eabf8631
- Article: NATURE METABOLISM. 2021;3(5):636-650
- Article: NATURE. 2020;588(7839):712-716
- Article: PLOS GENETICS. 2020;16(12):e1009242
- Article: SCIENCE ADVANCES. 2020;6(35):eaba8271
- Article: EMBO MOLECULAR MEDICINE. 2020;12(7):e11659
- Article: MOLECULAR CELL. 2019;76(5):784-796.e6
- Article: CELL REPORTS. 2019;29(6):1728-1738.e9
- Article: PLOS GENETICS. 2019;15(6):e1008085
- Article: EMBO REPORTS. 2019;20(6):embr201948101
- Article: SCIENCE ADVANCES. 2019;5(4):eaav9824
- Article: NATURE MEDICINE. 2018;24(11):1696-1700
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(41):E9620-E9629
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2018;46(13):6642-6669
- Article: CELL REPORTS. 2018;23(1):127-142
- Article: NATURE COMMUNICATIONS. 2018;9(1):1202
- Article: MOLECULAR CELL. 2018;69(1):9-23.e6
- Article: NATURE COMMUNICATIONS. 2017;8(1):1532
- Article: ELIFE. 2017;6:e30952
- Article: CELL METABOLISM. 2017;26(2):429-436.e4
- Article: ELIFE. 2017;6:e24662
- Article: SLAS DISCOVERY. 2017;22(4):378-386
- Article: CELL REPORTS. 2016;16(11):2980-2990
- Article: CELL REPORTS. 2016;16(9):2387-2398
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2016;44(14):6868-6882
- Article: CELL REPORTS. 2016;16(7):1874-1890
- Article: SCIENCE ADVANCES. 2016;2(8):e1600963
- Article: NATURE COMMUNICATIONS. 2016;7:11884
- Article: HUMAN MOLECULAR GENETICS. 2015;24(25):7286-7294
- Article: NATURE COMMUNICATIONS. 2015;6:8808
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(36):11288-11293
- Article: PLOS GENETICS. 2015;11(8):e1005423
- Article: JOURNAL OF CELL BIOLOGY. 2015;208(4):429-442
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2014;42(22):13920-13938
- Article: CELL METABOLISM. 2014;20(6):1069-1075
- Article: HUMAN MOLECULAR GENETICS. 2014;23(23):6345-6355
- Article: DIABETES. 2014;63(12):4100-4114
- Article: HUMAN MOLECULAR GENETICS. 2014;23(21):5733-5749
- Article: THE FASEB JOURNAL. 2014;28(10):4408-4419
- Article: MECHANISMS OF AGEING AND DEVELOPMENT. 2014;139:22-30
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2014;42(6):3638-3647
- Article: PLOS GENETICS. 2014;10(2):e1004110
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;443(1):7-12
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2014;42(2):1111-1116
- Article: NATURE. 2013;501(7467):412-415
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(22):15510-15519
- Article: HUMAN MOLECULAR GENETICS. 2013;22(10):1983-1993
- Article: CELL METABOLISM. 2013;17(4):618-626
- Article: PLOS GENETICS. 2013;9(1):e1003178
- Article: CELL METABOLISM. 2012;16(6):765-776
- Article: EMBO REPORTS. 2012;13(12):1130-1137
- Article: HUMAN MOLECULAR GENETICS. 2012;21(22):4827-4835
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2012;122(11):4048-4058
- Article: NATURE GENETICS. 2012;44(11):1282-1285
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(41):16510-16515
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(38):15253-15258
- Article: HUMAN MOLECULAR GENETICS. 2012;21(5):1078-1089
- Article: EMBO JOURNAL. 2012;31(2):443-456
- Article: CELL METABOLISM. 2012;15(1):100-109
- Article: JIMD REPORTS. 2012;4:67-73
- Article: ANTIOXIDANTS AND REDOX SIGNALING. 2011;15(9):2455-2464
- Article: PLOS GENETICS. 2011;7(10):e1002324
- Article: STEM CELLS. 2011;29(9):1459-1468
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(33):13534-13539
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(31):12937-12942
- Article: CELL METABOLISM. 2011;13(5):527-539
- Article: CELL METABOLISM. 2011;13(4):361-366
- Article: THE FASEB JOURNAL. 2011;25(4):1333-1344
- Article: HUMAN MOLECULAR GENETICS. 2011;20(6):1212-1223
- Article: PLOS GENETICS. 2011;7(3):e1002028
- Article: CELL METABOLISM. 2011;13(1):80-91
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(46):20087-20092
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2010;38(19):6577-6588
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;398(4):759-764
- Article: NEUROMUSCULAR DISORDERS. 2010;20(3):198-203
- Article: GENES, BRAIN AND BEHAVIOR. 2010;9(2):173-181
- Article: CELL METABOLISM. 2010;11(1):93
- Article: JOURNAL OF NEUROSCIENCE. 2009;29(50):15923-15932
- Article: CELL METABOLISM. 2009;10(2):131-138
- Article: PLOS GENETICS. 2009;5(5):e1000499
- Article: CELL METABOLISM. 2009;9(4):386-397
- Article: HUMAN MOLECULAR GENETICS. 2009;18(2):278-288
- Article: HUMAN MOLECULAR GENETICS. 2008;17(10):1418-1426
- Article: PLOS BIOLOGY. 2008;6(1):e10-71
- Article: JOURNAL OF PHYSIOLOGY. 2008;586(1):175-184
- Article: EXPERIMENTAL CELL RESEARCH. 2007;313(18):3924-3934
- Article: CELL. 2007;130(2):273-285
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(4):1325-1330
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(49):37972-37979
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;350(1):202-207
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(50):17993-17998
- Article: EMBO JOURNAL. 2005;24(23):4061-4070
- Article: ANNALS OF NEUROLOGY. 2005;58(4):544-552
- Article: CURRENT GENETICS. 2005;48(4):265-269
- Article: HUMAN MOLECULAR GENETICS. 2005;14(8):1069-1076
- Article: EMBO JOURNAL. 2004;23(23):4606-4614
- Article: NATURE. 2004;429(6990):417-423
- Article: HUMAN MOLECULAR GENETICS. 2004;13(9):935-944
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(9):3136-3141
- Article: MAMMALIAN GENOME. 2003;14(1):1-6
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(23):15066-15071
- Article: BEST PRACTICE AND RESEARCH: CLINICAL OBSTETRICS AND GYNAECOLOGY. 2002;16(5):715-728
- Article: NATURE GENETICS. 2002;31(3):289-294
- Article: METHODS IN MOLECULAR BIOLOGY. 2002;197:391-400
- Article: JOURNAL OF NEUROSCIENCE. 2001;21(20):8082-8090
- Article: MAMMALIAN GENOME. 2001;12(10):787-792
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(7):4038-4043
- Article: NATURE GENETICS. 2000;26(3):336-340
- Article: PRENATAL DIAGNOSIS. 2000;20(5):426-431
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(7):3467-3472
- Article: NATURE GENETICS. 1999;21(1):133-137
- Article: NATURE GENETICS. 1998;18(3):231-236
- Article: HUMAN MOLECULAR GENETICS. 1997;6(2):185-191
- Article: MAMMALIAN GENOME. 1997;8(2):139-140
- Article: NATURE GENETICS. 1996;13(3):296-302
- Article: HUMAN GENETICS. 1996;97(3):269-273
- Article: HUMAN GENETICS. 1995;96(3):290-294
- Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 1995;54(4):581-587
- Article: EUROPEAN JOURNAL OF PEDIATRICS. 1995;154(1):35-42
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All other publications
- Review: ANNUAL REVIEW OF BIOCHEMISTRY. 2024;93(1):47-77
- Review: MOLECULAR CELL. 2023;83(6):832-842
- Corrigendum: THE FASEB JOURNAL. 2021;35(6):e21633
- Review: FEBS LETTERS. 2021;595(8):976-1002
- Editorial comment: NATURE METABOLISM. 2020;2(8):673-675
- Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2020;287(6):589-591
- Corrigendum: NATURE MEDICINE. 2018;24(12):1940
- Editorial comment: CELL. 2018;172(1-2):388-388.e1
- Review: CELL METABOLISM. 2017;25(4):765-776
- Review: CELL METABOLISM. 2017;25(1):57-71
- Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2016;1857(8):1277-1283
- Review: ANNUAL REVIEW OF BIOCHEMISTRY. 2016;85:133-160
- Editorial comment: CELL METABOLISM. 2015;21(5):660-661
- Letter: NATURE. 2014;514(7521):E7-11
- Review: PLOS GENETICS. 2014;10(10):e1004670
- Review: CELL METABOLISM. 2014;20(2):226-240
- Review: TRENDS IN CELL BIOLOGY. 2013;23(9):457-463
- Review: JOURNAL OF INTERNAL MEDICINE. 2013;273(6):529-543
- Review: JOURNAL OF CLINICAL INVESTIGATION. 2013;123(3):951-957
- Editorial comment: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2011;18(11):1179-1181
- Editorial comment: PLOS BIOLOGY. 2011;9(8):e1001129
- Review: JOURNAL OF CELL BIOLOGY. 2011;193(5):809-818
- Editorial comment: CELL METABOLISM. 2010;12(1):3-4
- Review: ANNUAL REVIEW OF BIOCHEMISTRY. 2010;79:683-706
- Letter: CELL METABOLISM. 2010;11(1):1
- Editorial comment: CELL. 2009;139(2):231-233
- Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1787(5):484-490
- Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1787(5):296-302
- Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2009;265(2):170-173
- Review: NATURE REVIEWS GENETICS. 2008;9(9):657-662
- Editorial comment: CELL METABOLISM. 2008;7(4):278-279
- Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2008;263(2):114-116
- Published conference paper: JOURNAL OF INTERNAL MEDICINE. 2008;263(2):167-178
- Editorial comment: CELL. 2007;131(3):448-450
- Review: NOVARTIS FOUNDATION SYMPOSIUM. 2007;287:197-208
- Review: ANNUAL REVIEW OF BIOCHEMISTRY. 2007;76:679-699
- Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2004;1659(2-3):148-152
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2004;93(10):1268-1270
- Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2004;1658(1-2):122-132
- Editorial comment: ANNALS OF NEUROLOGY. 2002;52(5):529-530
- Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2002;1555(1-3):106-110
- Review: METHODS IN ENZYMOLOGY. 2002;353:409-421
- Review: TRENDS IN MOLECULAR MEDICINE. 2001;7(12):578-581
- Published conference paper: ACTA PHYSIOLOGICA. 2001;171(3):385-393
- Review: HUMAN REPRODUCTION. 2000;15 Suppl 2:86-91
- Review: FEBS LETTERS. 1999;455(3):199-202
- Review: JOURNAL OF INTERNAL MEDICINE. 1999;246(1):11-23
- Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1995;1271(1):249-252
- Published conference paper: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. 1995;22(4):284-287
- Review: ANNUAL REVIEW OF GENETICS. 1995;29:151-178
- Other: ACTA NEUROPATHOLOGICA. 1995;90(3):328-333
- Published conference paper: MUSCLE AND NERVE. 1995;3:S102-S106
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