Johan Lundberg's research group
Molecular imaging, neuropsychopharmacology, mood and anxiety disorders

The overriding aim of our research is to improve the treatment of major psychiatric disorders. Our main activity involves in vivo and post mortem molecular imaging to study the pathophysiology and pharmacology of mood and anxiety disorders, and to some extent autism spectrum disorders.
One vision of the group is to develop imaging markers for antidepressant treatment response. To this end, we study the molecular effect in man in vivo of different antidepressant treatments, such as Cognitive Behavioral Treatment, antidepressant drug treatment, Electro Convulsive Treatment and novel antidepressant treatments such as ketamine. We have had a focus on the serotonin system, but are performing studies also on the GABA and Glutamate systems. The development of molecular imaging analysis and statistics is an integrated part of our work.
Our work is supported by the Swedish Science Council, the Stockholm County, the Söderström-Königska foundation and from a generous private donation.
Group members
Media appearances
UR Samtiden Hjärndagen 2019 - Depression-en sjukdom och dess behandling
https://urplay.se/program/215072-ur-samtiden-hjarndagen-2019-depression…
Selected publications
Lundberg J, Cars T, Lööv SÅ, Söderling J, Sundström J, Tiihonen J, Leval A, Gannedahl A, Björkholm C, Själin M, Hellner C
JAMA psychiatry 2023;80(2):167-175
Price Rb, Kissel N, Baumeister A, Rohac R, Woody Ml, Ballard Ed, Zarate Ca, Deakin W, Abdallah Cg, Feder A, Charney Ds, Grunebaum Mf, Mann Jj, Mathew Sj, Gallagher B, Mcloughlin Dm, Murrough Jw, Muthukumaraswamy S, Mcmillan R, Sumner R, Papakostas G, Fava M, Hock R, Phillips Jl, Blier P, Shiroma P, Šóš P, Su Tp, Chen Mh, Tiger M, Lundberg J, Wilkinson St, Wallace Ml
Molecular psychiatry 2022;27(12):5096-5112
Lundberg J, Cars T, Lööv SÅ, Söderling J, Tiihonen J, Leval A, Gannedahl A, Björkholm C, Själin M, Hellner C
Acta psychiatrica Scandinavica 2022;146(1):51-63
Veldman Er, Varrone A, Varnas K, Svedberg Mm, Cselenyi Z, Tiger M, Gulyas B, Halldin C, Lundberg J
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 2022;42(4):630-641
Veldman Er, Mamula D, Jiang H, Tiger M, Ekman Cj, Lundberg J, Svenningsson P
Journal of affective disorders 2021;290():240-244
Serotonin transporter availability increases in patients recovering from a depressive episode
Svensson Je, Svanborg C, Plavén-sigray P, Kaldo V, Halldin C, Schain M, Lundberg J
Translational psychiatry 2021;11(1):264-
Serotonin transporter availability in adults with autism-a positron emission tomography study
Andersson M, Tangen Ä, Farde L, Bölte S, Halldin C, Borg J, Lundberg J
Molecular psychiatry 2021;26(5):1647-1658
Tiger M, Veldman Er, Ekman Cj, Halldin C, Svenningsson P, Lundberg J
TRANSLATIONAL PSYCHIATRY 2020;10(1):159-
Tiger M, Svensson J, Liberg B, Saijo T, Schain M, Halldin C, Farde L, Lundberg J
Psychiatry and clinical neurosciences 2020;74(4):263-269
Svensson Je, Schain M, Plavén-sigray P, Cervenka S, Tiger M, Nord M, Halldin C, Farde L, Lundberg J
NeuroImage 2019;202():116143-