Mikael Tiger

Publications
CV
Public outreach and news

Articles

Article: JOURNAL OF AFFECTIVE DISORDERS. 2025;386:119419
Risk of major adverse cardiovascular events in treatment-resistant or severe depression
Nygren A; Reutfors J; Karlsson P; Tiger M; Faxen J; Brenner P
Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2024;177:24-30
Long-term follow-up on patient attitudes towards renewed ECT: A register-based cohort study
Kronsell A; Nordenskjold A; Mittendorfer-Rutz E; Tiger M
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2024;27(5):pyae021
Altered Serotonin 1B Receptor Binding After Escitalopram for Depression Is Correlated With Treatment Effect
Garde M; Matheson GJ; Varnaes K; Svenningsson P; Hedman-Lagerloef E; Lundberg J; Farde L; Tiger M
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2023;26(4):241-248
Associations Between Cognition and Serotonin 1B Receptor Availability in Healthy Volunteers: A [¹¹C]AZ10419369 Positron Emission Tomography Study
Tangen A; Veldman ER; Svensson J; Tiger M; Nord M; Sorjonen K; Andersson M; Plaven-Sigray P; Varrone A; Halldin C; Varnas K; Borg J; Lundberg J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2023;323:292-298
Utilization of antidepressants, anxiolytics, and hypnotics during the COVID-19 pandemic in Scandinavia
Tiger M; Wesselhoeft R; Karlsson P; Handal M; Bliddal M; Cesta CE; Skurtveit S; Reutfors J
Article: BJPSYCH OPEN. 2023;9(2):e35
Response to electroconvulsive therapy in treatment-resistant depression: nationwide observational follow-up study
Nygren A; Reutfors J; Brandt L; Boden R; Nordenskjoeld A; Tiger M
Article: MOLECULAR PSYCHIATRY. 2022;27(12):5096-5112
International pooled patient-level meta-analysis of ketamine infusion for depression: In search of clinical moderators
Price RB; Kissel N; Baumeister A; Rohac R; Woody ML; Ballard ED; Zarate CAJ; Deakin W; Abdallah CG; Feder A; Charney DS; Grunebaum MF; Mann JJ; Mathew SJ; Gallagher B; McLoughlin DM; Murrough JW; Muthukumaraswamy S; McMillan R; Sumner R; Papakostas G; Fava M; Hock R; Phillips JL; Blier P; Shiroma P; Sos P; Su T-P; Chen M-H; Tiger M; Lundberg J; Wilkinson ST; Wallace ML
Article: INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE. 2022;26(3):251-258
Health care utilisation in treatment-resistant depression: a Swedish population-based cohort study
Brenner P; Nygren A; Hagg D; Tiger M; O'Hara M; Brandt L; Reutfors J
Article: NEUROPSYCHOPHARMACOLOGY. 2022;47(10):1863-1868
In vivo correlation of serotonin transporter and 1B receptor availability in the human brain: a PET study
Svensson JE; Tiger M; Plaven-Sigray P; Halldin C; Schain M; Lundberg J
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):226
Patterns of activity correlate with symptom severity in major depressive disorder patients
Spulber S; Elberling F; Svensson J; Tiger M; Ceccatelli S; Lundberg J
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022;42(4):630-641
Serotonin 1B receptor density mapping of the human brainstem using positron emission tomography and autoradiography
Veldman ER; Varrone A; Varnas K; Svedberg MM; Cselenyi Z; Tiger M; Gulyas B; Halldin C; Lundberg J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;294:645-651
A positron emission tomography study of the serotonin1B receptor effect of electroconvulsive therapy for severe major depressive episodes
Tiger M; Garde M; Tateno A; Matheson GJ; Sakayori T; Nogami T; Moriya H; Varnas K; Arakawa R; Okubo Y
Article: FRONTIERS IN NEUROSCIENCE. 2021;15:698633
Plasma Levels of Brain-Derived Neurotrophic Factor and S100B in Relation to Antidepressant Response to Ketamine
Jiang H; Veldman ER; Tiger M; Ekman C-J; Lundberg J; Svenningsson P
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;290:240-244
P11 (S100A10) as a potential predictor of ketamine response in patients with SSRI-resistant depression
Veldman ER; Mamula D; Jiang H; Tiger M; Ekman C-J; Lundberg J; Svenningsson P
Article: BJPSYCH OPEN. 2021;7(2):e71
The effect of anaesthetic dose on response and remission in electroconvulsive therapy for major depressive disorder: nationwide register-based cohort study
Kronsell A; Nordenskjold A; Bell M; Amin R; Mittendorfer-Rutz E; Tiger M
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2020;74(8):424-430
Low dopamine transporter binding in the nucleus accumbens in geriatric patients with severe depression
Moriya H; Tiger M; Tateno A; Sakayori T; Masuoka T; Kim W; Arakawa R; Okubo Y
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2020;301:111086
Electroconvulsive therapy decreases striatal dopamine transporter binding in patients with depression: A positron emission tomography study with [ 18 F]FE-PE2I
Masuoka T; Tateno A; Sakayori T; Tiger M; Kim W; Moriya H; Ueda S; Arakawa R; Okubo Y
Article: TRANSLATIONAL PSYCHIATRY. 2020;10(1):159
A randomized placebo-controlled PET study of ketamine′s effect on serotonin_1B receptor binding in patients with SSRI-resistant depression
Tiger M; Veldman ER; Ekman C-J; Halldin C; Svenningsson P; Lundberg J
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2020;74(4):263-269
[¹¹C]raclopride positron emission tomography study of dopamine-D_2/3 receptor binding in patients with severe major depressive episodes before and after electroconvulsive therapy and compared to control subjects
Tiger M; Svensson J; Liberg B; Saijo T; Schain M; Halldin C; Farde L; Lundberg J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2019;259:296-301
Less memory complaints with reduced stimulus dose during electroconvulsive therapy for depression
Kronsell A; Nordenskjold A; Tiger M
Article: NEUROIMAGE. 2019;202:116143
Validity and reliability of extrastriatal [¹¹C]raclopride binding quantification in the living human brain
Svensson JE; Schain M; Plaven-Sigray P; Cervenka S; Tiger M; Nord M; Halldin C; Farde L; Lundberg J
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2017;267:15-21
Associations between cognition and serotonin receptor 1B binding in patients with major depressive disorder - A pilot study.
Tangen Ä; Borg J; Tiger M; Varnäs K; Sorjonen K; Lindefors N; Halldin C; Lundberg J
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2016;253:36-42
Low serotonin_1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder
Tiger M; Farde L; Ruck C; Varrone A; Forsberg A; Lindefors N; Halldin C; Lundberg J
Article: NEUROIMAGE. 2014;103:303-308
Distinct regional age effects on [¹¹C]AZ10419369 binding to 5-HT_1B receptors in the human brain
Nord M; Cselenyi Z; Forsberg A; Rosenqvist G; Tiger M; Lundberg J; Varrone A; Farde L
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2014;68(10):480-483
No correlation between serotonin and its metabolite 5-HIAA in the cerebrospinal fluid and [(11) C]AZ10419369 binding measured with PET in healthy volunteers.
Tiger M; Svenningsson P; Nord M; Jabre S; Halldin C; Lundberg J
Article: PSYCHIATRY RESEARCH. 2014;223(2):164-170
Reduced 5-HT_1B receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder
Tiger M; Ruck C; Forsberg A; Varrone A; Lindefors N; Halldin C; Farde L; Lundberg J
Article: NEUROBIOLOGY OF AGING. 2014;35(4):867-875
Positron emission tomography imaging of 5-hydroxytryptamine_1B receptors in Parkinson's disease
Varrone A; Svenningsson P; Forsberg A; Varnas K; Tiger M; Nakao R; Halldin C; Nilsson L-G; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2012;15(8):1167-1172
Serotonin transporter occupancy with TCAs and SSRIs: a PET study in patients with major depressive disorder
Lundberg J; Tiger M; Landen M; Halldin C; Farde L
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;321(1):226-233
Ligand-induced alpha2-adrenoceptor endocytosis: relationship to Gi protein activation.
Olli-Lähdesmäki T; Tiger M; Vainio M; Scheinin M; Kallio J
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All other publications

Preprint: BIORXIV. 2024;BIORXIV
A Reference Tissue Implementation of Simultaneous Multifactor Bayesian Analysis (SiMBA) of PET Time Activity Curve Data.
Matheson GJ; Lundberg J; Gärde M; Veldman ER; Tateno A; Okubo Y; Tiger M; Ogden RT
Review: LAKARTIDNINGEN. 2024;121:23195
[Psychedelic psychiatry].
López E; Yngwe H; Beckman M; Tiger M; Hieronymus F; Lundberg J
Review: TRANSLATIONAL PSYCHIATRY. 2024;14(1):175
Utilization of antidepressants, anxiolytics, and hypnotics during the COVID-19 pandemic
Tiger M; Castelpietra G; Wesselhoeft R; Lundberg J; Reutfors J
Letter: NEUROIMAGE. 2020;207:116371
In response to the letter "[¹¹C]raclopride and extrastriatal binding to D2/3 receptors"
Svensson JE; Schain M; Plaven-Sigray P; Cervenka S; Tiger M; Nord M; Halldin C; Farde L; Lundberg J
Review: PSYCHOPHARMACOLOGY. 2018;235(5):1317-1334
The 5-HT_1B receptor - a potential target for antidepressant treatment
Tiger M; Varnas K; Okubo Y; Lundberg J
Doctoral thesis: 2014
PET studies of the serotonin system in major depression and its treatment
Tiger M

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2023-2026

Degrees and Education

Docent, Karolinska Institutet, 2022
Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2014

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