Katarina Varnäs

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Articles

Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2024;27(5):pyae021
Altered Serotonin 1B Receptor Binding After Escitalopram for Depression Is Correlated With Treatment Effect
Garde M; Matheson GJ; Varnaes K; Svenningsson P; Hedman-Lagerloef E; Lundberg J; Farde L; Tiger M
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(17):3206-3211
PET Evaluation of the Novel F-18 Labeled Reversible Radioligand [¹⁸F]GEH200449 for Detection of Monoamine Oxidase-B in the Non-Human Primate Brain
Varnas K; Nag S; Halldin C; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2023;26(4):241-248
Associations Between Cognition and Serotonin 1B Receptor Availability in Healthy Volunteers: A [¹¹C]AZ10419369 Positron Emission Tomography Study
Tangen A; Veldman ER; Svensson J; Tiger M; Nord M; Sorjonen K; Andersson M; Plaven-Sigray P; Varrone A; Halldin C; Varnas K; Borg J; Lundberg J
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022;42(4):630-641
Serotonin 1B receptor density mapping of the human brainstem using positron emission tomography and autoradiography
Veldman ER; Varrone A; Varnas K; Svedberg MM; Cselenyi Z; Tiger M; Gulyas B; Halldin C; Lundberg J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;294:645-651
A positron emission tomography study of the serotonin1B receptor effect of electroconvulsive therapy for severe major depressive episodes
Tiger M; Garde M; Tateno A; Matheson GJ; Sakayori T; Nogami T; Moriya H; Varnas K; Arakawa R; Okubo Y
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2021;64(16):12003-12021
[¹¹C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins
Liu L; Johnson PD; Prime ME; Khetarpal V; Lee MR; Brown CJ; Chen X; Clark-Frew D; Coe S; Conlon M; Davis R; Ensor S; Esposito S; Moren AF; Gai X; Green S; Greenaway C; Haber J; Halldin C; Hayes S; Herbst T; Herrmann F; He-mann M; Hsai MM; Kotey A; Mangette JE; Mills MR; Monteagudo E; Nag S; Nibbio M; Orsatti L; Schaertl S; Scheich C; Sproston J; Stepanov V; Varnas K; Varrone A; Wityak J; Mrzljak L; Munoz-Sanjuan I; Bard JA; Dominguez C
Article: NEURO-ONCOLOGY. 2021;23(4):687-696
Brain exposure of the ATM inhibitor AZD1390 in humans-a positron emission tomography study
Jucaite A; Stenkrona P; Cselenyi Z; De Vita S; Buil-Bruna N; Varnas K; Savage A; Varrone A; Johnstrom P; Schou M; Davison C; Sykes A; Reddy VP; Hoch M; Vazquez-Romero A; Moein MM; Halldin C; Merchant MS; Pass M; Farde L
Article: CLINICAL CANCER RESEARCH. 2021;27(1):189-201
Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs
Colclough N; Chen K; Johnstrom P; Strittmatter N; Yan Y; Wrigley GL; Schou M; Goodwin R; Varnas K; Adua SJ; Zhao M; Nguyen DX; Maglennon G; Barton P; Atkinson J; Zhang L; Janefeldt A; Wilson J; Smith A; Takano A; Arakawa R; Kondrashov M; Malmquist J; Revunov E; Vazquez-Romero A; Moein MM; Windhorst AD; Karp NA; Finlay MRV; Ward RA; Yates JWT; Smith PD; Farde L; Cheng Z; Cross DAE
Article: BRITISH JOURNAL OF ANAESTHESIA. 2021;126(1):238-244
Effects of sevoflurane anaesthesia on radioligand binding to monoamine oxidase-B in vivo
Varnas K; Finnema SJ; Johnstrom P; Arakawa R; Halldin C; Eriksson LI; Farde L
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(24):4398-4404
Synthesis and Autoradiography of Novel F-18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B
Nag S; Jia Z; Svedberg M; Jackson A; Ahmad R; Luthra S; Varnas K; Farde L; Halldin C
Article: MOLECULAR BRAIN. 2020;13(1):164
Altered striatal dopamine levels in Parkinson's disease VPS35 D620N mutant transgenic aged mice
Vanan S; Zeng X; Chia SY; Varnas K; Jiang M; Zhang K; Saw WT; Padmanabhan P; Yu W-P; Zhou Z-D; Halldin C; Gulyas B; Tan E-K; Zeng L
Article: SYNAPSE. 2020;74(10):e22157
Autoradiographic mapping of synaptic vesicle glycoprotein 2A in non-human primate and human brain
Varnas K; Stepanov V; Halldin C
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(7):1048-1057
Synthesis, Biodistribution, and Radiation Dosimetry of a Novel mGluR5 Radioligand: ¹⁸F-AZD9272
Nag S; Varnas K; Arakawa R; Jahan M; Schou M; Farde L; Halldin C
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2020;40(4):799-807
A PET study in healthy subjects of brain exposure of ¹¹C-labelled osimertinib - A drug intended for treatment of brain metastases in non-small cell lung cancer
Varrone A; Varnas K; Jucaite A; Cselenyi Z; Johnstrom P; Schou M; Vazquez-Romero A; Moein MM; Halldin C; Brown AP; Vishwanathan K; Farde L
Article: NEUROPHARMACOLOGY. 2020;162:107809
The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans
Varnas K; Cselenyi Z; Arakawa R; Nag S; Stepanov V; Moein MM; Johnstrom P; Kingston L; Elmore CS; Halldin C; Farde L
Article: BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 2019;29(13):1624-1627
Synthesis and preclinical evaluation of [¹⁸F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B
Dahl K; Bernard-Gauthier V; Nag S; Varnas K; Narayanaswami V; Moein MM; Arakawa R; Vasdev N; Halldin C
Article: BRAIN RESEARCH. 2019;1711:140-145
In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [¹⁸F]MNI-659
Svedberg MM; Varnas K; Varrone A; Mitsios N; Mulder J; Gulyas B; Beaumont V; Munoz-Sanjuan I; Zaleska MM; Schmidt CJ; Halldin C; Mrzljak L
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(2):367-375
PET imaging of [¹¹C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding
Varnas K; Cselenyi Z; Jucaite A; Halldin C; Svenningsson P; Farde L; Varrone A
Article: SCIENCE ADVANCES. 2018;4(6):eaat1719
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models
Durant ST; Zheng L; Wang Y; Chen K; Zhang L; Zhang T; Yang Z; Riches L; Trinidad AG; Fok JHL; Hunt T; Pike KG; Wilson J; Smith A; Colclough N; Reddy VP; Sykes A; Janefeldt A; Johnstrom P; Varnas K; Takano A; Ling S; Orme J; Stott J; Roberts C; Barrett I; Jones G; Roudier M; Pierce A; Allen J; Kahn J; Sule A; Karlin J; Cronin A; Chapman M; Valerie K; Illingworth R; Pass M
Article: NEUROPHARMACOLOGY. 2018;135:455-463
The metabotropic glutamate receptor 5 radioligand [¹¹C]AZD9272 identifies unique binding sites in primate brain
Varnas K; Jureus A; Finnema SJ; Johnstrom P; Raboisson P; Amini N; Takano A; Stepanov V; Halldin C; Farde L
Article: ACS CHEMICAL NEUROSCIENCE. 2018;9(5):906-911
Development of [Carbonyl-¹¹C]AZ13198083, a Novel Histamine Type-3 Receptor Radioligand with Favorable Kinetics
Dahl K; Nakao R; Amini N; Moein MM; Finnema S; Malmquist J; Varnas K; Schou M
Article: ACS CHEMICAL NEUROSCIENCE. 2018;9(2):224-229
Discovery of a Novel Muscarinic Receptor PET Radioligand with Rapid Kinetics in the Monkey Brain
Malmquist J; Varnas K; Svedberg M; Vallee F; Albert JS; Finnema SJ; Schou M
Article: PSYCHIATRY RESEARCH - NEUROIMAGING. 2017;267:15-21
Associations between cognition and serotonin receptor 1B binding in patients with major depressive disorder - A pilot study.
Tangen Ä; Borg J; Tiger M; Varnäs K; Sorjonen K; Lindefors N; Halldin C; Lundberg J
Article: JOURNAL OF NUCLEAR MEDICINE. 2017;58(4):617-622
Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral Cortex
Haggkvist J; Toth M; Tari L; Varnas K; Svedberg M; Forsberg A; Nag S; Dominguez C; Munoz-Sanjuan I; Bard J; Wityak J; Varrone A; Halldin C; Mrzljak L
Article: PSYCHOPHARMACOLOGY. 2017;234(4):707-716
GABA_A receptor occupancy by subtype selective GABA_Aα2,3 modulators: PET studies in humans
Jucaite A; Cselenyi Z; Lappalainen J; McCarthy DJ; Lee C-M; Nyberg S; Varnas K; Stenkrona P; Halldin C; Cross A; Farde L
Article: CLINICAL CANCER RESEARCH. 2016;22(20):5130-5140
Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity
Ballard P; Yates JWT; Yang Z; Kim D-W; Yang JC-H; Cantarini M; Pickup K; Jordan A; Hickey M; Grist M; Box M; Johnstrom P; Varnas K; Malmquist J; Thress KS; Janne PA; Cross D
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2016;358(3):464-471
Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
Varnas K; Jureus A; Johnstrom P; Ahlgren C; Schott P; Schou M; Gruber S; Jerning E; Malmborg J; Halldin C; Afzelius L; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2016;19(8):pyw023
Neurokinin-3 Receptor Binding in Guinea Pig, Monkey, and Human Brain: In Vitro and in Vivo Imaging Using the Novel Radioligand, [¹⁸F]Lu AF10628
Varnas K; Finnema SJ; Stepanov V; Takano A; Toth M; Svedberg M; Nielsen SM; Khanzhin NA; Juhl K; Bang-Andersen B; Halldin C; Farde L
Article: NEUROIMAGE. 2016;133:313-320
Mapping the distribution of serotonin transporter in the human brainstem with high-resolution PET: Validation using postmortem autoradiography data
Fazio P; Schain M; Varnas K; Halldin C; Farde L; Varrone A
Article: ACS CHEMICAL NEUROSCIENCE. 2016;7(2):177-184
Discovery and Preclinical Validation of [¹¹C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor
Schou M; Varnas K; Jureus A; Ahlgren C; Malmquist J; Haggkvist J; Tari L; Wesolowski SS; Throner SR; Brown DG; Nilsson M; Johnstrom P; Finnema SJ; Nakao R; Amini N; Takano A; Farde L
Article: NEUROPHARMACOLOGY. 2016;101:519-530
A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates
Hjorth S; Karlsson C; Jucaite A; Varnas K; Hamren UW; Johnstrom P; Gulyas B; Donohue SR; Pike VW; Halldin C; Farde L
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2015;58(20):8200-8215
Discovery and Evaluation of Clinical Candidate AZD3759, a Potent, Oral Active, Central Nervous System-Penetrant, Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
Zeng Q; Wang J; Cheng Z; Chen K; Johnstrom P; Varnas K; Li DY; Yang ZF; Zhang X
Article: BRAIN. 2015;138(Pt 9):2687-2700
Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease
Jucaite A; Svenningsson P; Rinne JO; Cselenyi Z; Varnas K; Johnstrom P; Amini N; Kirjavainen A; Helin S; Minkwitz M; Kugler AR; Posener JA; Budd S; Halldin C; Varrone A; Farde L
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2015;80(1):116-127
Estimation of drug receptor occupancy when non-displaceable binding differs between brain regions - extending the simplified reference tissue model
Kagedal M; VarnaS K; Hooker AC; Karlsson MO
Article: NUCLEAR MEDICINE AND BIOLOGY. 2015;42(6):555-560
Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing
Johnstrom P; Bergman L; Varnas K; Malmquist J; Halldin C; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2015;18(10):pyv036
Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates
Schou M; Varnas K; Lundquist S; Nakao R; Amini N; Takano A; Finnema SJ; Halldin C; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2014;18(3):pyu081
Amphetamine Decreases α_2C-Adrenoceptor Binding of [¹¹C]ORM-13070: A PET Study in the Primate Brain
Finnema SJ; Hughes ZA; Haaparanta-Solin M; Stepanov V; Nakao R; Vamas K; Varrone A; Arponen E; Marjamaki P; Pohjanoksa K; Vuorilehto L; Babalola PA; Solin O; Grimwood S; Sallinen J; Farde L; Scheinin M; Halldin C
Article: NEUROINFORMATICS. 2014;12(4):551-562
Evaluation of Two Automated Methods for PET Region of Interest Analysis
Schain M; Varnas K; Cselenyi Z; Halldin C; Farde L; Varrone A
Article: MOLECULAR IMAGING AND BIOLOGY. 2014;16(2):173-179
Synthesis, Radiolabeling, and In Vivo Pharmacokinetic Evaluation of the Amyloid Beta Radioligand [¹¹C]AZD4694 in Nonhuman Primates
Schou M; Varnas K; Sandell J; Johnstrom P; Cselenyi Z; Svensson S; Nakao R; Amini N; Bergman L; Sumic A; Gulyas B; Lindstrom-Boo E; Halldin C; Farde L
Article: NEUROBIOLOGY OF AGING. 2014;35(4):867-875
Positron emission tomography imaging of 5-hydroxytryptamine_1B receptors in Parkinson's disease
Varrone A; Svenningsson P; Forsberg A; Varnas K; Tiger M; Nakao R; Halldin C; Nilsson L-G; Farde L
Article: SYNAPSE. 2014;68(3):89-97
Low Brain CB1 Receptor Occupancy by a Second Generation CB1 Receptor Antagonist TM38837 in Comparison With Rimonabant in Nonhuman Primates: A PET Study
Takano A; Gulyas B; Varnaes K; Little PB; Noerregaard PK; Jensen NO; Elling CE; Halldin C
Article: NEUROSCIENCE LETTERS. 2014;559:163-168
Antidepressant effects on serotonin 1A/1B receptors in the rat brain using a gene x environment model
Shrestha SS; Pine DS; Luckenbaugh DA; Varnas K; Henter ID; Innis RB; Mathe AA; Svenningsson P
Article: NEUROIMAGE. 2013;82:160-169
A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066-Estimating occupancy in the absence of a reference region
Kadgedal M; Cselenyi Z; Nyberg S; Raboisson P; Stahle L; Stenkrona P; Varnas K; Halldin C; Hooker AC; Karlsson MO
Article: NUCLEAR MEDICINE AND BIOLOGY. 2013;40(6):747-754
Radiosynthesis and evaluation of new α₁-adrenoceptor antagonists as PET radioligands for brain imaging
Airaksinen AJ; Finnema SJ; Balle T; Varnas K; Bang-Andersen B; Gulyas B; Farde L; Halldin C
Article: CEPHALALGIA. 2013;33(10):853-860
A PET study with [¹¹C]AZ10419369 to determine brain 5-HT_1B receptor occupancy of zolmitriptan in healthy male volunteers
Varnas K; Jucaite A; McCarthy DJ; Stenkrona P; Nord M; Halldin C; Farde L; Kanes S
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2013;33(7):1058-1065
Arterial input function derived from pairwise correlations between PET-image voxels
Schain M; Benjaminsson S; Varnas K; Forsberg A; Halldin C; Lansner A; Farde L; Varrone A
Article: NUCLEAR MEDICINE AND BIOLOGY. 2013;40(3):410-414
Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate
Schou M; Varnas K; Jucaite A; Gulyas B; Halldin C; Farde L
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40(4):580-593
Low background and high contrast PET imaging of amyloid-β with [¹¹C]AZD2995 and [¹¹C]AZD2184 in Alzheimer's disease patients
Forsberg A; Jureus A; Cselenyi Z; Eriksdotter M; Freund-Levi Y; Jeppsson F; Swahn B-M; Sandell J; Julin P; Schou M; Andersson J; Johnstrom P; Varnas K; Halldin C; Farde L; Svensson S
Article: EJNMMI RESEARCH. 2012;2:15
Kinetic analysis and test-retest variability of the radioligand [¹¹C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects
Jucaite A; Cselenyi Z; Arvidsson A; Ahlberg G; Julin P; Varnas K; Stenkrona P; Andersson J; Halldin C; Farde L
Article: JOURNAL OF NUCLEAR MEDICINE. 2012;53(3):415-424
Clinical Validation of ¹⁸F-AZD4694, an Amyloid-β-Specific PET Radioligand
Cselenyi Z; Jonhagen ME; Forsberg A; Halldin C; Julin P; Schou M; Johnstrom P; Varnas K; Svensson S; Farde L
Article: PSYCHOPHARMACOLOGY. 2011;213(2-3):533-545
Dose-dependent binding of AZD3783 to brain 5-HT_1B receptors in non-human primates and human subjects: a positron emission tomography study with [¹¹C]AZ10419369
Varnas K; Nyberg S; Karlsson P; Pierson ME; Kagedal M; Cselenyi Z; McCarthy D; Xiao A; Zhang M; Halldin C; Farde L
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2011;31(1):113-123
Quantitative analysis of [¹¹C]AZ10419369 binding to 5-HT_1B receptors in human brain
Varnas K; Nyberg S; Halldin C; Varrone A; Takano A; Karlsson P; Andersson J; McCarthy D; Smith M; Pierson ME; Soderstrom J; Farde L
Article: SYNAPSE. 2010;64(10):733-741
Radiosynthesis of the Candidate β-Amyloid Radioligand [¹¹C]AZD2184: Positron Emission Tomography Examination and Metabolite Analysis in Cynomolgus Monkeys
Andersson JD; Varnas H; Cselenyi Z; Gulyas B; Wensbo D; Finnema SJ; Swahn B-M; Svensson S; Nyberg S; Farde L; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36(11):1859-1863
Detection of amyloid in Alzheimer's disease with positron emission tomography using [¹¹C]AZD2184
Nyberg S; Jonhagen ME; Cselenyi Z; Halldin C; Julin P; Olsson H; Freund-Levi Y; Andersson J; Varnas K; Svensson S; Farde L
Article: BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 2009;19(21):6209-6212
Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors
Donohue SR; Varnas K; Jia Z; Gulyas B; Pike VW; Halldin C
Article: NEUROIMAGE. 2009;47(1):213-219
Local and covariate-modulated false discovery rates applied in neuroimaging
Lawyer G; Ferkingstad E; Nesvag R; Varnas K; Agartz I
Article: CEREBELLUM. 2009;8(1):52-60
Grey and White Matter Proportional Relationships in the Cerebellar Vermis Altered in Schizophrenia
Lawyer G; Nesvag R; Varnas K; Okugawa G; Agartz I
Article: PSYCHIATRY RESEARCH. 2008;164(3):254-264
Investigating possible subtypes of schizophrenia patients and controls based on brain cortical thickness
Lawyer G; Nesvag R; Varnas K; Frigessi A; Agartz I
Article: NEUROIMAGE. 2008;41(3):1075-1085
[¹¹C]AZ10419369:: A selective 5-HT_1B receptor radioligand suitable for positron emission tomography (PET).: Characterization in the primate brain
Pierson ME; Andersson J; Nyberg S; McCarthy DJ; Finnema SJ; Varnas K; Takano A; Karlsson P; Gulyas B; Medd AM; Lee C-M; Powell ME; Heys JR; Potts W; Seneca N; Mrzljak L; Farde L; Halldin C
Article: SCHIZOPHRENIA RESEARCH. 2008;98(1-3):16-28
Regional thinning of the cerebral cortex in schizophrenia:: Effects of diagnosis, age and antipsychotic medication
Nesvag R; Lawyer G; Varnas K; Fjell AM; Walhovd KB; Frigessi A; Jonsson EG; Agartz I
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2007;61(3):326-329
Cerebellar volumes in men with schizophrenia and alcohol dependence
Varnas K; Okugawa G; Hammarberg A; Nesvag R; Rimol LM; Franck J; Agartz I
Article: SYNAPSE. 2005;56(1):21-28
Regional expression of 5-HT_1B receptor mRNA in the human brain
Varnäs K; Hurd YL; Hall H
Article: NEUROSCIENCE LETTERS. 2004;367(3):313-316
Distribution of 5-HT₇ receptors in the human brain:: a preliminary autoradiographic study using [³H]SB-269970
Varnäs K; Thomas DR; Tupala E; Tiihonen J; Hall H
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2003;13(4):228-234
Distribution of 5-HT₄ receptors in the postmortem human brain -: an autoradiographic study using [¹²⁵I]SB 207710
Varnäs K; Halldin C; Pike VW; Hall H
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2003;304(1):81-87
Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity
Chalon S; Tarkiainen J; Garreau L; Hall H; Emond P; Vercouillie J; Farde L; Dasse P; Varnas K; Besnard JC; Halldin C; Guilloteau D
Article: NUCLEAR MEDICINE AND BIOLOGY. 2002;29(4):389-398
Synthesis and biological evaluation of technetium(III) mixed-ligand complexes with high affinity for the cerebral 5-HT_1A receptor and the alpha1-adrenergic receptor
Drews A; Pietzsch HJ; Syhre R; Seifert S; Varnäs K; Hall H; Halldin C; Kraus W; Karlsson P; Johnsson C; Spies H; Johannsen B
Article: NUCLEAR MEDICINE AND BIOLOGY. 2002;29(4):375-387
Synthesis, biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high affinity for the 5-HT_1A receptor and the alpha1-adrenergic receptor
Heimbold I; Drews A; Kretzschmar M; Varnäs K; Hall H; Halldin C; Syhre R; Kraus W; Pietzsch HJ; Seifert S; Brust P; Johannsen B
Article: BIOLOGIA FUTURA. 2002;53(1-2):59-66
Autoradiographic evaluation of [¹¹C]vinpocetine binding in the human postmortem brain
Hall H; Varnäs K; Sandell J; Halldin C; Farde L; Vas A; Kárpáti E; Gulyás B
Article: BRAIN RESEARCH. 2001;915(1):47-57
Autoradiographic mapping of 5-HT_1B and 5-HT_1D receptors in the post mortem human brain using [³H]GR 125743
Varnäs K; Hall H; Bonaventure P; Sedvall G
Article: NUCLEAR MEDICINE AND BIOLOGY. 2001;28(2):177-185
New halogenated [¹¹C]WAY analogues, [¹¹C]6FPWAY and [¹¹C]6BPWAY -: Radiosynthesis and assessment as radioligands for the study of brain 5-HT_1A receptors in living monkey
Sandell J; Halldin C; Pike VW; Chou YH; Varnäs K; Hall H; Marchais S; Nowicki B; Wikström HV; Swahn CG; Farde L
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All other publications

Review: PSYCHOPHARMACOLOGY. 2018;235(5):1317-1334
The 5-HT_1B receptor - a potential target for antidepressant treatment
Tiger M; Varnas K; Okubo Y; Lundberg J
Review: CLINICAL AND TRANSLATIONAL IMAGING. 2017;5(3):291-298
PET microdosing of CNS drugs
Schou M; Varnas K
Review: JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. 2013;40(3):267-279
Modeling of PET data in CNS drug discovery and development
Varnas K; Varrone A; Farde L
Meeting abstract: NEUROIMAGE. 2010;52:S61-S62
Amphetamine decreases binding of the novel alpha2C-adrenoreceptor radioligand [11C]ORM-13070 in monkey brain
Finnema SJ; Varnas K; Stepanov V; Varrone A; Gulyas B; Arponen E; Helin S; Solin O; Haaparanta M; Sallinen J; Ingman K; Scheinin M; Farde L; Halldin C
Meeting abstract: NEUROIMAGE. 2010;52:S142
Quantification and wavelet-aided parametric imaging of cerebral amyloid using the HRRT PET-system and [18F]AZD4694
Cselenyi Z; Jonhagen ME; Forsberg A; Halldin C; Julin P; Schou M; Johnstroem P; Varnas K; Svensson S; Farde L
Corrigendum: PSYCHIATRY RESEARCH - NEUROIMAGING. 2009;171(3):258
Investigating possible subtypes of schizophrenia patients and controls based on brain cortical thickness (vol 164, pg 254, 2008)
Lawyer G; Nesvag R; Varnas K; Frigessi A; Agartz I
Published conference paper: PSYCHIATRIC GENETICS. 2008;18(4):177-183
Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia
Varnas K; Lawyer G; Jonsson EG; Kulle B; Nesvag R; Hall H; Terenius L; Agartz I
Thesis / dissertation: 2005
Distribution of serotonin receptors and transporters in the human brain : implications for psychosis
Varnäs, Katarina
Published conference paper: HUMAN BRAIN MAPPING. 2004;22(3):246-260
Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain
Varnäs K; Halldin C; Hall H

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Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2023-2026

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Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2005

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