Gunilla Karlsson Hedestam group
Our research focuses on the function of B lymphocytes and qualitative properties of antibody repertoires. A specific interest in the group is to understand individual variation in antibody germline (VDJ) genes and how this influences the elicitation of antigen-specific B cell responses.
Resources
IgDiscover
The computational tool, IgDiscover, allows the production of individualized genetic profiles of adaptive immune receptor V, D and J genes, which is central for many areas of research and personalized medicine applications.
VDJ Databases
The latest set of VDJ alleles reported in Vázquez Bernat et al., available for download and assignments.