Oscar Fernandez-Capetillo group

The Fernández-Capetillo laboratory focuses on the use of cell-based phenotypic screens for the development of new medicines. Neglected until rather recently, due to a focus on target-oriented drug development, phenotypic screens have yielded some of the most important medical advances to our societies. With the help of automatized microscopes, the laboratory designs phenotypic screens that aim to mimic a disease condition.

Oscar Frenandez-Capetillo group

Our research

Our current interests are spread among a variety of topics, where we believe that the use of automatized microscopy and phenotypic screens can contribute. Examples include the search for new treatments for neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) or Huntington disease (HD); investigating ways of potentiating the immune response; identifying molecules that modulate RNA translation or exploring the links between female hormones in the context of inflammatory diseases. To do so, we capitalize on our expertise in chemical screens, and we seek collaborations with national and international groups that help us bring our discoveries as far as possible.

Besides our own work, and together with Prof. Karin Forsberg, we coordinate a research community program named PHENOTARGET, supported by SciLifeLab, which brings together more than 30 Swedish research groups with a common interest on Phenotype Drug Discovery in Human disease.

Alumni

  • Wareed Ahmed, postdoctoral researcher, 2020-2022
  • Alba Corman, PhD student, 2017-2022
  • Patrycia Michalska Dziama, postdoctoral researcher, 2020-2021
  • Pranauti Rajesh Panshikar, master student, 2020-2021
  • Valeria Colicchia, postdoctoral researcher, 2018-2021
  • Mimmi Olofsson, master student, 2021
  • Jordi Carreras-Puigvert, project leader and assistant professor, 2015-2020
  • Marlene Wolfsgruber, Bachelor student, 2020
  • Catherine Hansel, postdoctoral researcher, 2018-2020
  • Schayan Yousefian, master student, 2018-2019
  • Mirela Balan, postdoctoral researcher, 2018
  • Alba González, bachelor student Erasmus+, 2017-2018
  • Melania Zauri, postdoctoral researcher, 2017-2018
  • Pablo Marti Rodrigo, graduate research fellow, 2017-2018
  • Pournima Prabhakaran, master student, 2017
  • Kirsten Tschapalda, postdoctoral researcher, 2016-2017
  • Bomi Jung, postdoctoral researcher, 2016-2017
  • Jon Vallejo, visiting PhD student, 2016

Publications

Selected publications

Members and contact

Group leader

All members of the group