Daniela Hühn

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Articles

Article: EBIOMEDICINE. 2024;103:105124
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ γ
Li X; Hernandez I; Koyuncu S; Haeggblad M; Lidemalm L; Abbas AA; Bendeguz S; Goebloes A; Brautigam L; Lucas JJ; Carreras-Puigvert J; Huehn D; Pircs K; Vilchez D; Fernandez-Capetillo O
Article: MICROPUBLICATION BIOLOGY. 2023;2023:10.17912/micropub.biology
A chemical screen underscores the essential role of STAT1-dependent IFNγ signaling to regulate HLA-I expression in cancer cells.
Barz M; Porebski B; Panshikar P; Häggbladd M; Hühn D; Fernandez-Capetillo O
Article: FEBS OPEN BIO. 2022;12(10):1896-1908
New regulators of the tetracycline-inducible gene expression system identified by chemical and genetic screens
Colicchia V; Haggblad M; Sirozh O; Porebski B; Balan M; Li X; Lidemalm L; Carreras-Puigvert J; Huhn D; Fernandez-Capetillo O
Article: MOLECULAR ONCOLOGY. 2022;16(1):148-165
Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells
Huhn D; Marti-Rodrigo P; Mouron S; Hansel C; Tschapalda K; Porebski B; Haggblad M; Lidemalm L; Quintela-Fandino M; Carreras-Puigvert J; Fernandez-Capetillo O
Article: CELL DEATH AND DIFFERENTIATION. 2020;27(2):773-789
The antimalarial drug amodiaquine stabilizes p53 through ribosome biogenesis stress, independently of its autophagy-inhibitory activity
Espinoza JA; Zisi A; Kanellis DC; Carreras-Puigvert J; Henriksson M; Huhn D; Watanabe K; Helleday T; Lindstrom MS; Bartek J
Article: CELL CHEMICAL BIOLOGY. 2019;26(2):235-243.e5
A Chemical Screen Identifies Compounds Limiting the Toxicity of C9ORF72 Dipeptide Repeats
Corman A; Jung B; Haggblad M; Brautigam L; Lafarga V; Lidemalm L; Huhn D; Carreras-Puigvert J; Fernandez-Capetillo O
Article: JOURNAL OF CELL BIOLOGY. 2016;214(4):401-415
RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells
Urban V; Dobrovolna J; Huhn D; Fryzelkova J; Bartek J; Janscak P
Article: ONCOGENE. 2015;34(30):3977-3984
miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP.
Hühn D; Kousholt AN; Sørensen CS; Sartori AA
Article: MOLECULAR CELL. 2013;50(3):333-343
Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection.
Steger M; Murina O; Hühn D; Ferretti LP; Walser R; Hänggi K; Lafranchi L; Neugebauer C; Paliwal S; Janscak P; Gerrits B; Del Sal G; Zerbe O; Sartori AA
Article: PLANT PHYSIOLOGY. 2011;155(3):1435-1444
Nonsymbiotic hemoglobin-2 leads to an elevated energy state and to a combined increase in polyunsaturated fatty acids and total oil content when overexpressed in developing seeds of transgenic Arabidopsis plants.
Vigeolas H; Hühn D; Geigenberger P
Article: NUCLEIC ACIDS RESEARCH (NAR). 2010;38(22):8131-8140
RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription.
Kanagaraj R; Huehn D; MacKellar A; Menigatti M; Zheng L; Urban V; Shevelev I; Greenleaf AL; Janscak P
Article: JOURNAL OF CELL SCIENCE. 2009;122(Pt 8):1258-1267
p300-mediated acetylation of the Rothmund-Thomson-syndrome gene product RECQL4 regulates its subcellular localization.
Dietschy T; Shevelev I; Pena-Diaz J; Hühn D; Kuenzle S; Mak R; Miah MF; Hess D; Fey M; Hottiger MO; Janscak P; Stagljar I
Article: PLANT PHYSIOLOGY. 2003;133(4):2048-2060
Lipid storage metabolism is limited by the prevailing low oxygen concentrations within developing seeds of oilseed rape.
Vigeolas H; van Dongen JT; Waldeck P; Huhn D; Geigenberger P

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Review: SWISS MEDICAL WEEKLY. 2013;143:w13837
Targeting DNA double-strand break signalling and repair: recent advances in cancer therapy.
Hühn D; Bolck HA; Sartori AA

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