Henrik Druid's Group

We conduct research that aims at improving the diagnostic forensic casework. We also participate in preclinical research on tissue turnover, and carry out studies on pathophysiological mechanisms behind various medical conditions caused by disease and injury states. Several projects involve collaboration with the Swedish National Board of Forensic Medicine, and with researchers at KI and several other universities.

We are running several projects in parallel representing both basic and translational research, particularly aiming at developing methods to improve the postmortem diagnosis of severe medical conditions.
We are running several projects in parallel representing both basic and translational research, particularly aiming at developing methods to improve the postmortem diagnosis of severe medical conditions. Although having different focus, the projects have several points of contacts.

Projects

Group members

Principal investigators

Henrik Druid, MD, Professor
CV Henrik Druid

Kanar Alkass, PhD, associate prof.
Lydia Kahn, MD, PhD
Brita Zilg, MD, PhD

Associated group members

Maria Jepsen, BSc
Magnus Lundberg, MD, PhD
Nenad Bogdanovic, MD, PhD
Nina Heldring, PhD
Anja Petaros, MD, PhD
Eva Rudd, MD, PhD

Postdocs

Kie Horioka, PhD

PhD Students

Rebecka Teglind, MSc (Bone Age, PI: Kanar Alkass)
Daniel Andersson, MD (Traumatic brain injury, PI: Henrik Druid)
Denise Guggenheimer, MD (Homicide studies, PI: Brita Zilg)
Cecilia Besev Swing, MD (Opioid toxicity, PI: Lydia Kahn)
Anton Mittendorf, MD (injury pattern, PI: Brita Zilg)
Anna Jinghede, dentist, scene invest. (child abuse, PI:Brita Zilg)

Project students

Anna Kawaguchi
Julia Mielcarz

Project assistant

Deni Rashid

KI Donatum

Kanar Alkass, PhD, kanar.alkass@ki.se

Former group members

Guest researchers

Shinya Kasai, Ass. Prof (2017-2019)
Ahmed Mousa, PhD (2012-2016)
Sasikala K. Nil, Professor (2004)

Postdocs

Akira Hayakawa, MD, PhD (2021-2022)
Kie Horioka PhD (2020)
Tara Wardi LeMaitre, PhD (2014-2018)
Lydia Kahn MD, PhD(2010-2014)
Hisako Saitoh MD(2010-2011)
Olof Bendel, PhD (2008-2009)
Fredrik C. Kugelberg, PhD (2005-2006)

PhD students

Gopalakrishnan Dhanabalan
Lotta Walz
Carl Söderberg
Brita Zilg
Kanar Alkass
Joakim Strandberg
Sofi Bäcklin
Madeleine Granlind
Lars-Eric Bergman

Project and exchange students

Supervisor Henrik Druid unless otherwise stated

Deni Rashid; supervisor Kanar Alkass (2023)
Klaske Osinga (2023)
Deni Rashid; supervisor Kanar Alkass (2022)
Malin Persson; supervisor Lydia Kahn (2022)
Emma Molander; supervisor Brita Zilg (2022)
Sebastian Gode (2022)
Nicelle Myhrberg (2022)
Sofia Andersson (2022)
Elin Haupt; supervisor Brita Zilg (2022)
Amanda Jonsson; supervisor Lydia Kahn (2022)
Paula Tolsa Ortega (2022)
Constanze Kohout; supervisor Kanar Alkass (2022)
Natalie Avigdor (2021)
Sofia Riehl (2021)
Panagiota Tselekidou (2021)
Jasmijn Maljaars; supervisor Kanar Alkass (2021)
Cecilia Magnusson; supervisor Brita Zilg (2021)
Linnea Aurich; supervisor Lydia Kahn (2021)
Hanna Tengelin; supervisor Lydia Kahn (2021)
Tobias Björkman; supervisor Lydia Kahn (2021)
Erik Alexandersson, supervisor Lydia Kahn (2021)
Isabel Auer; supervisor: Lydia Kahn (2020)
Yakub Eriksson Hydara; supervisor Brita Zilg (2020)
Simon Ström supervisor Brita Zilg (2020)
Gustav Wärn supervisor Brita Zilg (2020)
Kristoffer Hahn; supervisor: Lydia Kahn (2019)
Evelyn Maitz, supervisor Kanar Alkass (2019)
Dominika Begolli; supervisor: Kanar Alkass (2019)
Johan Pieniowski (2019)
Sibon Kabir (2019)
Hanna Hedlund (2019)
Frida Soneborg (2019)
Alice Ljungström (2018)
Michael Moridi; supervisor: Brita Zilg (2018)
Cassandra Cieslak; supervisor Kanar Alkass (2017)
Carolina Goncalves (2017)
Emma Gustafsson (2016)
Caroline Ytterman (2016)
Meta Byström (2015)
Hampus Fabricius (2015)
George Hamnström (2014)
Sabria Belarbi (2014)
Marina Montmany (2014)
Niklas Sjökvist (2014)
Sandra Koskinen (2013)
Joelle Vos (2013)
Erik Bivehed (2013)
Joan Raouf (2011)
Ann Ståhle (2011)
Jenny Rönnlund (2011)
Evan Reed (2010)
Sara Hassanzaddeh (2010)
Annika Andersson (2009)
Stephanie Harney (2009)
Hampus Janko (2009)
Anke Böhmer (2008)
Siv Andersson (2008)
Stina Norlin (2008)
Nina Granberg (2008)
Lisen Bredberg (2006)
Midia Hussein (2006)
Brita Zilg (2006)
Aziz Bitar (2005)
Anna Gustavsson (2005)
Elias Malko (2005)
Cecilia Hult (2004)
Peggy Törn (2004)
Elias Palm (2004)
Sofia Hausel (2002)

Research Nurse

Isabella Cereceda (2003-2009)

Selected publications

A DNA methylation atlas of normal human cell types.
Loyfer N, Magenheim J, Peretz A, Cann G, Bredno J, Klochendler A, Fox-Fisher I, Shabi-Porat S, Hecht M, Pelet T, Moss J, Drawshy Z, Amini H, Moradi P, Nagaraju S, Bauman D, Shveiky D, Porat S, Dior U, Rivkin G, Or O, Hirshoren N, Carmon E, Pikarsky A, Khalaileh A, Zamir G, Grinbaum R, Abu Gazala M, Mizrahi I, Shussman N, Korach A, Wald O, Izhar U, Erez E, Yutkin V, Samet Y, Rotnemer Golinkin D, Spalding KL, Druid H, Arner P, Shapiro AMJ, Grompe M, Aravanis A, Venn O, Jamshidi A, Shemer R, Dor Y, Glaser B, Kaplan T
Nature 2023 Jan;613(7943):355-364

A Rapid Method for Postmortem Vitreous Chemistry-Deadside Analysis.
Zilg B, Alkass K, Kronstrand R, Berg S, Druid H
Biomolecules 2021 Dec;12(1):

Effects of Alcohol Abuse on Proliferating Cells, Stem/Progenitor Cells, and Immature Neurons in the Adult Human Hippocampus.
Le Maître TW, Dhanabalan G, Bogdanovic N, Alkass K, Druid H
Neuropsychopharmacology 2018 03;43(4):690-699

A new model for the estimation of time of death from vitreous potassium levels corrected for age and temperature.
Zilg B, Bernard S, Alkass K, Berg S, Druid H
Forensic Sci. Int. 2015 Sep;254():158-66

Neurogenesis in the striatum of the adult human brain.
Ernst A, Alkass K, Bernard S, Salehpour M, Perl S, Tisdale J, et al
Cell 2014 Feb;156(5):1072-83

Dynamics of hippocampal neurogenesis in adult humans.
Spalding KL, Bergmann O, Alkass K, Bernard S, Salehpour M, Huttner HB, et al
Cell 2013 Jun;153(6):1219-1227

Analysis of radiocarbon, stable isotopes and DNA in teeth to facilitate identification of unknown decedents.
Alkass K, Saitoh H, Buchholz BA, Bernard S, Holmlund G, Senn DR, et al
PLoS ONE 2013 ;8(7):e69597

Evidence for cardiomyocyte renewal in humans.
Bergmann O, Bhardwaj RD, Bernard S, Zdunek S, Barnabé-Heider F, Walsh S, et al
Science 2009 Apr;324(5923):98-102

Forensics: age written in teeth by nuclear tests.
Spalding KL, Buchholz BA, Bergman LE, Druid H, Frisén J
Nature 2005 Sep;437(7057):333-4

A compilation of fatal and control concentrations of drugs in postmortem femoral blood.
Druid H, Holmgren P
J. Forensic Sci. 1997 Jan;42(1):79-87

 

05-07-2023