Stefan Skare´s research group
Neuroradiology – MRI physics
The research group consists of MR physicists at Karolinska University Hospital and GE Healthcare, and develops new imaging methods for brain MRI. The research consists of software development of new acquisition methods (a.k.a. pulse sequences) and image reconstruction methods for brain MRI, with integration in a clinical environment. A criteria for our research projects are that they should also be implemented in the clinical routine, and today about 20% of the clinical MR images at the Dept. of Neuroradiology are acquired with in-house developed software. The methods developed may also come to good use for other departments and hospitals.
MRI is a slow imaging modality, where each image series typically takes several minutes to acquire. This requires that the patient is capable of remaining still during the data acquisition, and a complete MR exam takes between 30-60 min. Our research group have two major R&D projects to address this fundamental problem in MRI. One project is about acceleration techniques (SMS - simultaneous multi-slice) for 2D pulse sequences that are used clinically. This aims to reduce the imaging time for each series in the MR exam, which implies less risk of head motion as well as shorter MR examinations overall. The other, and the most central, project for the group is prospective (and retrospective) motion correction for the range of MR image contrasts that are used clinically. This will allow patients to freely move their head during the MR examination without loss in the diagnostic image quality or confidence. This is of particular interest for brain MRI of children, where the goal is also to significantly reduce the number of MR examinations with the patient under general anesthesia (GA).
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