Cell-based immune therapy for cancer – Andreas Lundqvist's Group

Our research focuses to understand mechanisms of immune escape in solid tumors.

Andreas Lundqvist's research group.

Our research

The immune system plays an important role to prevent local growth and dissemination of cancer. Therapies based on activating the immune system can result in beneficial responses in patients with cancer. In order to harness the full potential of the immune system T and NK cells need to colonize tumors as well as to display optimal tumor killing potential. We investigate the ability of T and NK cells to migrate towards tumors, to persist within the tumor microenvironment, and to maintain the ability to and recognize and kill tumor cells. We study how T and NK cells interact with cells within the tumor microenvironment and exploit cellular and molecular mechanisms of tumor-induced immunosuppression to develop improved immunotherapy regimens in patients with cancer.

Publications

Selected publications

Staff and contact

Group leader

All members of the group

Alumni

Erik Wennerberg, The Institute of Cancer Research, London
Dhifaf Sarhan, Karolinska Institutet
Veronika Kremer, ‎Novartis
Kristina Witt, Oncopeptides
Maria Wolodarski, Karolinska University Hospital
Ziqing Chen, Princeton University
Shi Yong Neo, Agency for Science, Technology and Research (A*STAR), Singapore
Khang Luu, National University of Singapore