Andreas Lundqvist

Andreas Lundqvist

Professor
Telephone: +46852482371
Visiting address: J6:20 BioClinicum, Akademiska stråket 1, 17164 Solna
Postal address: K7 Onkologi-Patologi, K7 Forskning Lundqvist, 171 77 Stockholm

About me

  • Professor, Karolinska Institutet, Department of Oncology-Pathology, 2023

    Associate Professor, Karolinska Institutet, 2012
    Assistant Professor, Karolinska Institutet, 2009
    Staff Scientist, National Institutes of Health, 2008
    Research fellow, National Institutes of Health, 2005
    Postdoctoral fellow, National Institutes of Health, 2003
    PhD, Karolinska Institutet, 2003

Research

  • Our research focus on studies to understand how NK and T cells are regulated in patients with cancer. With this knowledge we aim to develop improved immunotherapies in patients with cancer.

Teaching

  • Completed ten weeks of pedagogic training courses.
    PhD course organizer: Tumor immunology and immune therapy of cancer (#3110), Karolinska Institutet.
    More than 500 hours teaching undergradates (BSc), post-graduates (MSc and PhD) and medical professionals (MD).

Articles

All other publications

Grants

  • The Swedish Childhood Cancer Fund
    1 January 2024 - 31 December 2025
  • Swedish Research Council
    1 January 2023 - 31 December 2026
    Due to their important role to eradicate tumors, natural killer (NK) cells are increasingly utilized in cancer immunotherapy. While the infusion of NK cells shows clinical benefit in hematological malignancies, NK cell therapy has yet to show therapeutic potential in patients with solid tumors. We recently discovered a unique subset of tumor-infiltrating NK cells that exert immune regulatory functions to inhibit anti-tumor T cell responses in solid tumors. Our preliminary results support that these NK cells also play a critical role to orchestrate changes within the tumor microenvironment and to affect epithelial-to-mesenchymal transition (EMT). In this project, we will use in vitro and in vivo models and ex vivo analysis of patient material to address how these NK cells remodel the tumor microenvironment via the crosstalk with myeloid cells, influence the EMT process to promote metastatic dissemination, and interfere with clinical responses to immune checkpoint therapy. In aggregate, we anticipate these studies will support the role of tumor-infiltrating NK cells to suppress local and systemic immune responses and favor tumor progression, metastatic dissemination, and interfere with therapy. Such findings have direct implications to improve therapies based on activating NK cell as well as to implement predictive and prognostic biomarkers in patients with cancer.
  • Barncancerfonden
    1 January 2023 - 31 December 2023
  • The Swedish Cancer Society
    1 January 2022 - 31 December 2024
  • The Cancer Research Funds of Radiumhemmet
    1 January 2022 - 31 December 2024

Employments

  • Professor, Department of Oncology-Pathology, Karolinska Institutet, 2023-

Degrees and Education

  • Doctor Of Philosophy, Department of Oncology-Pathology, Karolinska Institutet, 2003

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