Lisa Westerberg Group

The overall goal of our research is to understand how a compromised immune system leads to immunodeficiency with high incidence of autoimmunity and hematological cancers. We have a particular focus on how inborn mutations in actin regulators affect immune cell-cell communication, trafficking, and maintenance of genomic stability. Our research aims at revealing critical mechanisms for correct regulation of the immune system in health and disease and to identifying new targets for therapy.