Mattias Carlström group publications

AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis.
Cordero-Herrera I, Kozyra M, Zhuge Z, McCann Haworth S, Moretti C, Peleli M, et al
Proc. Natl. Acad. Sci. U.S.A. 2019 01;116(1):217-226

Therapeutic value of stimulating the nitrate-nitrite-nitric oxide pathway to attenuate oxidative stress and restore nitric oxide bioavailability in cardiorenal disease.
Carlstrom M, Montenegro MF
J. Intern. Med. 2019 01;285(1):2-18

Metabolic Effects of Dietary Nitrate in Health and Disease.
Lundberg JO, Carlström M, Weitzberg E
Cell Metab. 2018 Jul;28(1):9-22

Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress.
Yang T, Zhang XM, Tarnawski L, Peleli M, Zhuge Z, Terrando N, et al
Redox Biol 2017 10;13():320-330

Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation.
Hezel M, Peleli M, Liu M, Zollbrecht C, Jensen BL, Checa A, et al
Free Radic. Biol. Med. 2016 10;99():87-98

NADPH oxidase in the renal microvasculature is a primary target for blood pressure-lowering effects by inorganic nitrate and nitrite.
Gao X, Yang T, Liu M, Peleli M, Zollbrecht C, Weitzberg E, et al
Hypertension 2015 Jan;65(1):161-70

Renal autoregulation in health and disease.
Carlström M, Wilcox CS, Arendshorst WJ
Physiol. Rev. 2015 Apr;95(2):405-511

Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice.
Carlström M, Larsen FJ, Nyström T, Hezel M, Borniquel S, Weitzberg E, et al
Proc. Natl. Acad. Sci. U.S.A. 2010 Oct;107(41):17716-20

Peer-reviewed research review articles

Inorganic nitrate: A potential prebiotic for oral microbiota dysbiosis associated with type 2 diabetes.
Bahadoran Z, Mirmiran P, Carlström M, Ghasemi A
Nitric Oxide 2021 Nov;116():38-46

Nitric oxide signalling in kidney regulation and cardiometabolic health.
Carlström M
Nat Rev Nephrol 2021 Sep;17(9):575-590

Effects of inorganic nitrate supplementation on cardiovascular function and exercise tolerance in heart failure.
Ferguson SK, Woessner MN, Holmes MJ, Belbis MD, Carlström M, Weitzberg E, Allen JD, Hirai DM
J Appl Physiol (1985) 2021 Apr;130(4):914-922

Microbiota, diet and the generation of reactive nitrogen compounds.
Carlström M, Moretti CH, Weitzberg E, Lundberg JO
Free Radic Biol Med 2020 Dec;161():321-325

Modulation of mitochondria and NADPH oxidase function by the nitrate-nitrite-NO pathway in metabolic disease with focus on type 2 diabetes.
Schiffer TA, Lundberg JO, Weitzberg E, Carlström M
Biochim Biophys Acta Mol Basis Dis 2020 Aug;1866(8):165811

Nitric oxide: To be or not to be an endocrine hormone?
Bahadoran Z, Carlström M, Mirmiran P, Ghasemi A
Acta Physiol (Oxf) 2020 May;229(1):e13443

Therapeutic value of stimulating the nitrate-nitrite-nitric oxide pathway to attenuate oxidative stress and restore nitric oxide bioavailability in cardiorenal disease.
Carlstrom M, Montenegro MF
J. Intern. Med. 2019 01;285(1):2-18

Hydronephrosis and risk of later development of hypertension.
Carlström M
Acta Paediatr. 2019 01;108(1):50-57

Circulating markers of nitric oxide homeostasis and cardiometabolic diseases: insights from population-based studies.
Bahadoran Z, Mirmiran P, Jeddi S, Carlström M, Azizi F, Ghasemi A
Free Radic. Res. 2019 Apr;53(4):359-376

Metabolic Effects of Dietary Nitrate in Health and Disease.
Lundberg JO, Carlström M, Weitzberg E
Cell Metab. 2018 Jul;28(1):9-22

Mechanisms underlying blood pressure reduction by dietary inorganic nitrate.
Carlström M, Lundberg JO, Weitzberg E
Acta Physiol (Oxf) 2018 09;224(1):e13080

Pharmacological targeting of adenosine receptor signaling.
Peleli M, Fredholm BB, Sobrevia L, Carlström M
Mol. Aspects Med. 2017 06;55():4-8

Adenosine signaling in diabetes mellitus and associated cardiovascular and renal complications.
Peleli M, Carlstrom M
Mol. Aspects Med. 2017 06;55():62-74

Renal autoregulation in health and disease.
Carlström M, Wilcox CS, Arendshorst WJ
Physiol. Rev. 2015 Apr;95(2):405-511

Interactions between adenosine, angiotensin II and nitric oxide on the afferent arteriole influence sensitivity of the tubuloglomerular feedback.
Persson AE, Lai EY, Gao X, Carlström M, Patzak A
Front Physiol 2013 ;4():187

Roles of dietary inorganic nitrate in cardiovascular health and disease.
Lundberg JO, Carlström M, Larsen FJ, Weitzberg E
Cardiovasc. Res. 2011 Feb;89(3):525-32

Peer-reviewed Editorials, Letters and Commentaries

miR-27a in Extracellular Vesicles: Is It a Novel Modulator of Hypertension?
Carlström M, Braga VA
Am. J. Hypertens. 2020 01;33(1):21-22

The Other Glucose Transporter, SGLT1 - Also a Potential Trouble Maker in Diabetes?
Carlström M
J. Am. Soc. Nephrol. 2019 04;30(4):519-521

Mechanisms underlying the effects of renal denervation in renovascular hypertension.
Carlström M, Braga VA
Hypertens. Res. 2019 05;42(5):754-757

Therapeutic value of renal denervation in cardiovascular disease?
Carlstrom M
Acta Physiol (Oxf) 2017 05;220(1):11-13

Renal purinergic signalling in health and disease.
Persson AE, Carlström M
Acta Physiol (Oxf) 2015 Apr;213(4):805-7