Tomas Schiffer

Publications
CV
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Articles

Article: REDOX BIOLOGY. 2024;69:102984
Dimethyl malonate preserves renal and mitochondrial functions following ischemia-reperfusion via inhibition of succinate dehydrogenase
Carlstrom M; Carvalho LRRA; Guimaraes D; Boeder A; Schiffer TA
Article: REDOX BIOLOGY. 2022;51:102266
Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway
Li X; Zhuge Z; Carvalho LRRA; Braga VA; Lucena RB; Li S; Schiffer TA; Han H; Weitzberg E; Lundberg JO; Carlstrom M
Article: ELIFE. 2022;11:e70714
Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
Zheng X; Narayanan S; Xu C; Eliasson Angelstig S; Grunler J; Zhao A; Di Toro A; Bernardi L; Mazzone M; Carmeliet P; Del Sole M; Solaini G; Forsberg EA; Zhang A; Brismar K; Schiffer TA; Rajamand Ekberg N; Botusan IR; Palm F; Catrina S-B
Article: CLINICAL SCIENCE. 2021;135(19):2243-2263
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
Elksnis A; Schiffer TA; Palm F; Wang Y; Cen J; Turpaev K; Ngamjariyawat A; Younis S; Huang S; Shen Y; Leng Y; Bergsten P; Karlsborn T; Welsh N; Wang X
Article: ACTA PHYSIOLOGICA. 2021;231(3):e13581
Germ-free mice are not protected against diet-induced obesity and metabolic dysfunction
Moretti CH; Schiffer TA; Li X; Weitzberg E; Carlstrom M; Lundberg JO
Article: REDOX BIOLOGY. 2021;39:101836
Renovascular effects of inorganic nitrate following ischemia-reperfusion of the kidney
Zhang G; Han H; Zhuge Z; Dong F; Jiang S; Wang W; Guimaraes DD; Schiffer TA; Lai EY; Ribeiro Antonino Carvalho LR; Lucena RB; Braga VA; Weitzberg E; Lundberg JO; Carlstrom M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2020;160:860-870
Dietary nitrite extends lifespan and prevents age-related locomotor decline in the fruit fly
Moretti CH; Schiffer TA; Montenegro MF; Larsen FJ; Tsarouhas V; Carlstrom M; Samakovlis C; Weitzberg E; Lundberg JO
Article: ACTA PHYSIOLOGICA. 2020;229(3):e13463
Mitochondrial oxygen affinity increases after sprint interval training and is related to the improvement in peak oxygen uptake
Larsen FJ; Schiffer TA; Zinner C; Willis SJ; Morales-Alamo D; Calbet JAL; Boushel R; Holmberg H-C
Article: DIABETES-METABOLISM RESEARCH AND REVIEWS. 2019;35(2):e3091
Metformin attenuates renal medullary hypoxia in diabetic nephropathy through inhibition uncoupling protein-2
Christensen M; Schiffer TA; Gustafsson H; Krag SP; Norregaard R; Palm F
Article: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2018;315(3):F677-F681
Kidney outer medulla mitochondria are more efficient compared with cortex mitochondria as a strategy to sustain ATP production in a suboptimal environment
Schiffer TA; Gustafsson H; Palm F
Article: JOURNAL OF SPINAL CORD MEDICINE. 2018;41(1):85-90
Acute effects of glossopharyngeal insufflation in people with cervical spinal cord injury
Nygren-Bonnier M; Schiffer TA; Lindholm P
Article: FRONTIERS IN PHYSIOLOGY. 2018;9:1133
Superior Intrinsic Mitochondria Respiration in Women Than in Men
Cardinale DA; Larsen FJ; Schiffer TA; Morales-Alamo D; Ekblom B; Calbet JAL; Holmberg H-C; Boushel R
Article: PLOS ONE. 2018;13(11):e0207728
The effect of inactin on kidney mitochondrial function and production of reactive oxygen species
Schiffer TA; Christensen M; Gustafsson H; Palm F
Article: FRONTIERS IN PHYSIOLOGY. 2017;8:211
Mitochondrial Reactive Oxygen Species and Kidney Hypoxia in the Development of Diabetic Nephropathy
Schiffer TA; Friederich-Persson M
Article: PHYSIOLOGY & BEHAVIOR. 2017;168:55-61
Dietary nitrate markedly improves voluntary running in mice
Ivarsson N; Schiffer TA; Hernandez A; Lanner JT; Weitzberg E; Lundberg JO; Westerblad H
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2016;311(3):C452-C461
Control of human energy expenditure by cytochrome c oxidase subunit IV-2
Schiffer TA; Peleli M; Sundqvist ML; Ekblom B; Lundberg JO; Weitzberg E; Larsen FJ
Article: FRONTIERS IN PHYSIOLOGY. 2016;7:426
The Physiological Mechanisms of Performance Enhancement with Sprint Interval Training Differ between the Upper and Lower Extremities in Humans
Zinner C; Morales-Alamo D; Ortenblad N; Larsen FJ; Schiffer TA; Willis SJ; Gelabert-Rebato M; Perez-Valera M; Boushel R; Calbet JAL; Holmberg H-C
Article: FASEB JOURNAL. 2016;30(1):417-427
High-intensity sprint training inhibits mitochondrial respiration through aconitase inactivation
Larsen FJ; Schiffer TA; Ortenblad N; Zinner C; Morales-Alamo D; Willis SJ; Calbet JA; Holmberg H-C; Boushel R
Article: REDOX BIOLOGY. 2015;5:234-242
Effects of long-term dietary nitrate supplementation in mice
Hezel MP; Liu M; Schiffer TA; Larsen FJ; Checa A; Wheelock CE; Carlstrom M; Lundberg JO; Weitzberg E
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2015;44:88-97
Effects of hyperbaric oxygen on nitric oxide generation in humans
Uusijarvi J; Eriksson K; Larsson AC; Nihlen C; Schiffer T; Lindholm P; Weitzberg E
Article: FASEB JOURNAL. 2014;28(10):4303-4311
Dynamic regulation of metabolic efficiency explains tolerance to acute hypoxia in humans
Schiffer TA; Ekblom B; Lundberg JO; Weitzberg E; Larsen FJ
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2014;99(4):843-850
Dietary nitrate reduces resting metabolic rate: a randomized, crossover study in humans
Larsen FJ; Schiffer TA; Ekblom B; Mattsson MP; Checa A; Wheelock CE; Nystrom T; Lundberg JO; Weitzberg E
Article: PLOS ONE. 2014;9(7):e103402
KCNMA1 Encoded Cardiac BK Channels Afford Protection against Ischemia-Reperfusion Injury
Soltysinska E; Bentzen BH; Barthmes M; Hattel H; Thrush AB; Harper M-E; Qvortrup K; Larsen FJ; Schiffer TA; Losa-Reyna J; Straubinger J; Kniess A; Thomsen MB; Brueggemann A; Fenske S; Biel M; Ruth P; Wahl-Schott C; Boushel RC; Olesen S-P; Lukowski R
Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2013;113(3):803-810
Transient ischemic attacks from arterial gas embolism induced by glossopharyngeal insufflation and a possible method to identify individuals at risk
Schiffer TA; Lindholm P
Article: RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY. 2013;185(2):339-348
Effects of dietary inorganic nitrate on static and dynamic breath-holding in humans
Schiffer TA; Larsen FJ; Lundberg JO; Weitzberg E; Lindholm P
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2012;590(15):3575-3583
Dietary nitrate increases tetanic [Ca2+]i and contractile force in mouse fast-twitch muscle
Hernandez A; Schiffer TA; Ivarsson N; Cheng AJ; Bruton JD; Lundberg JO; Weitzberg E; Westerblad H
Article: FASEB JOURNAL. 2011;25(8):2843-2852
Mitochondrial oxygen affinity predicts basal metabolic rate in humans
Larsen FJ; Schiffer TA; Sahlin K; Ekblom B; Weitzberg E; Lundberg JO
Article: CELL METABOLISM. 2011;13(2):149-159
Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans
Larsen FJ; Schiffer TA; Borniquel S; Sahlin K; Ekblom B; Lundberg JO; Weitzberg E
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All other publications

Review: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 2020;1866(8):165811
Modulation of mitochondria and NADPH oxidase function by the nitrate-nitrite-NO pathway in metabolic disease with focus on type 2 diabetes
Schiffer TA; Lundberg JO; Weitzberg E; Carlstrom M
Letter: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2020;111(2):486
Dietary nitrate and mitochondrial efficiency in humans
Schiffer TA; Larsen F; Lundberg JO; Weitzberg E
Review: FREE RADICAL BIOLOGY AND MEDICINE. 2012;53(10):1919-1928
Regulation of mitochondrial function and energetics by reactive nitrogen oxides
Larsen FJ; Schiffer TA; Weitzberg E; Lundberg JO

Employments

Senior Research Specialist, Department of Physiology and Pharmacology, Karolinska Institutet, 2022-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Physiology and Pharmacology, Karolinska Institutet, 2014

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