Mattias Carlström

Mattias Carlström

Professor | Docent
Telephone: +46852486850
Visiting address: Solnavägen 9, Biomedicum B5, 17165 Solna
Postal address: C3 Fysiologi och farmakologi, C3 FyFa Reaktiva syreradikaler och kväveoxid i njur- och hjärtkärlforskning, 171 77 Stockholm
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About me

  • Mattias Carlström is Professor of Cardiorenal Physiology and group leader for Reactive oxygen species and nitric oxide signaling in Reno-Cardio-Metabolic Regulation at the Department of Physiology and Pharmacology.

    Education
    Professor of Cardiorenal Physiology, Karolinska Institutet, Dept. of Physiology &
  • Pharmacology (2022-)
    Associate Professor of Physiology, Karolinska Institutet, Dept. of Physiology &
  • Pharmacology (2015-2022)
    Adjunct Assistant Professor, Georgetown University, Washington DC, Dept. of Medicine, Div of Nephrology &
  • Hypertension (2011-)
    Postdoc: Georgetown University, Div. of Nephrology &
  • Hypertension, DC, USA, (2009-2011)
    Postdoc: Karolinska Institutet, Dept. of Physiology &
  • Pharmacology (2008-2009)
    PhD Medicine, Dept. of Medical Cell Biology, Uppsala University (2008)
    Degree of Master of Science in Pharmacy, Uppsala University (2003)
    Degree of Master of Science in Pharmaceutical Science, Uppsala University (2002)


    Academic honours, awards and prizes
    2022: SRP Diabetes - The Rolf Luft Grant for Instrumentation

    2019: Novo Nordisk Foundation (5 years) – Ascending Investigator Grant - Endocrinology &
  • Metabolism

    2019: Distinguished Professor, Weifang Medical University, China

    2019. Senior Research Award (2 years), Karolinska Institutet

    2017: Heart and Lung Foundation (3 years) – Prince Daniel’s Award, Sweden

    2015: Fo-Ass Research Grant (4 years), Karolinska Institutet

    2012: Lewis T. Preston Research Achievement Award, Georgetown University, USA

    2012: Top Young Investigator Award, ASN, Kidney Week, Philadelphia, USA

    2011: Lewis T. Preston Research Achievement Award, Georgetown University, USA

    2011: Fellows Forum Presentation Winner, National Kidney Foundation, NIH, USA

    2010: Young Investigator Award – Society Free Radical Biology Meeting, Orlando, USA

    2010: Fellows Forum Presentation Winner, National Kidney Foundation, NIH, USA

    2009: Young Investigator Award – 3rd Int. Meeting on the Role of Nitrite in Physiology, Pathophysiology, and Therapeutics, Sweden

    2007: Young Investigator Award - Scand. Physiol. Society Annual Meeting, Norway

Research

  • Emerging evidence suggests that renal oxidative stress and nitric oxide (NO) deficiency is linked to cardiovascular disease and diabetic complications. Mechanisms are not clear, but exaggerated NADPH oxidase- and mitochondria-derived superoxide production and NO deficiency may impair vascular function and lead to impairment of renal autoregulation. Using a translational design, our projects aim to characterize the mechanisms for superoxide and NO formation, interaction and influence on renal, cardiovascular and metabolic functions in health and disease. Novel dietary and pharmacological therapeutic strategies, focusing on dampening of vascular oxidative stress, are investigated and characterized in experimental disease models and in patients with reno-cardio-metabolic disorders, including chronic kidney disease, hypertension and type 2 diabetes.

Articles

All other publications

Employments

  • Professor, Department of Physiology and Pharmacology, Karolinska Institutet, 2022-

Degrees and Education

  • Docent, Karolinska Institutet, 2015

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