Helin Norberg lab – Protein degradation pathways

The focus of the lab is to dissect the cells own quality control mechanisms to develop novel therapeutic strategies to selectively target pathogenic proteins in cancer or other human disorders. To this end, the group study the molecular details of various fundamentally different protein degradation mechanisms, involving the autophagy-lysosome pathways. The lab encompasses full spectrum of investigations on both basic research and highly translational efforts using patient and animal experiments.