Petter Brodin
About me
Systems immunology lab developing novel technologies to profile human immune systems.
Research
Our multidisciplinary aims to understand human immune system variation in health and disease, its origins early in life and the influences of microbes and learning the principles of human immune system regulation. To achieve this we develop novel experimental and computational tools that enable systems-level analyses of all the white blood cells in human blood samples and their functional regulation.
As a physician/scientist at the department of pediatrics at the Karolinska University Hospital, I have a particular interest in understanding when and how human immune systems are shaped early in life, and how its regulation is disrupted in children with inflammatory diseases and cancers.
Teaching
Systems immunology, computational biology and pediatrics.
Articles
- Journal article: JOURNAL OF IMMUNOLOGY. 2024;213(10):1452-1466
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2024;45(1):31
- Article: SCIENTIFIC REPORTS. 2024;14(1):24512
- Journal article: JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY. 2024;13(Supplement_4):8-9
- Journal article: NATURE REVIEWS IMMUNOLOGY. 2024;24(10):697-698
- Journal article: NATURE REVIEWS IMMUNOLOGY. 2024;24(10):771
- Article: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 2024
- Article: NATURE. 2024;633(8028):155-164
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2024;221(9):e20231725
- Journal article: BMC MEDICINE. 2024;22(1):295
- Article: NATURE METHODS. 2024;21(6):1044-1052
- Journal article: BIORXIV. 2024;:2024.04.16.589585
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(4):e13346
- Journal article: CANCER RESEARCH. 2024;84(6):6378
- Article: NPJ VACCINES. 2024;9(1):42
- Article: NATURE. 2024;626(8000):827-835
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2024;221(2):e20231353
- Article: PEDIATRIC RESEARCH. 2024;95(3):762-769
- Article: CYTOMETRY. PART A : THE JOURNAL OF THE INTERNATIONAL SOCIETY FOR ANALYTICAL CYTOLOGY. 2024;105(2):124-138
- Article: SCIENCE. 2024;383(6680):eadg7942
- Article: SCIENCE IMMUNOLOGY. 2023;8(90):eabp8966
- Article: GUT MICROBES. 2023;15(2):2287618
- Article: NATURE. 2023;623(7988):803-813
- Journal article: CIRCULATION. 2023;148:a16646
- Journal article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2023;159:104065
- Article: ISCIENCE. 2023;26(8):107422
- Article: IMMUNITY. 2023;56(6):1255-1268.e5
- Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2023;41(16_suppl):3110
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):233.07
- Article: THE LANCET REGIONAL HEALTH. EUROPE. 2023;28:100608
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2023;220(5):e20220170
- Article: GENOME MEDICINE. 2023;15(1):22
- Article: THE LANCET RHEUMATOLOGY. 2023;5(4):e184-e199
- Article: SCIENCE. 2023;379(6632):eabo3627-20
- Article: OXFORD OPEN IMMUNOLOGY. 2023;4(1):iqad003
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(1):136-150
- Article: CELL REPORTS MEDICINE. 2022;3(11):100804
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2022;219(11):e20220514
- Article: NATURE COMMUNICATIONS. 2022;13(1):5895
- Article: MOLECULAR ONCOLOGY. 2022;16(19):3452-3464
- Article: SCIENTIFIC REPORTS. 2022;12(1):14937
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2022;219(8):e20220131
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(8):2415-2430
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2022;219(7):e20220202
- Article: CELL REPORTS. 2022;39(13):110989
- Journal article: FRONTIERS IN SYSTEMS BIOLOGY. 2022;2:918792
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(21):e2200413119
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: GLOBAL. 2022;1(2):37-42
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(5):1583-1595
- Article: GENES AND IMMUNITY. 2022;23(2):93-98
- Article: JAMA NETWORK OPEN. 2022;5(4):e228109
- Article: GENOME MEDICINE. 2022;14(1):28
- Article: NATURE IMMUNOLOGY. 2022;23(2):159-164
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2022;111(2):354-362
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(1):65-75.e8
- Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(12):2791-2796
- Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2021;32(8):1833-1842
- Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4348
- Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4340
- Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2021;40(1):240
- Article: CELL. 2021;184(15):3884-3898.e11
- Article: NEW ENGLAND JOURNAL OF MEDICINE. 2021;385(1):11-22
- Article: LAKARTIDNINGEN. 2021;118:21136
- Article: PSYCHONEUROENDOCRINOLOGY. 2021;126:105162
- Article: CELL REPORTS. 2021;34(11):108852
- Article: PEDIATRIC RESEARCH. 2021;89(3):604-612
- Article: IMMUNITY AND AGEING. 2021;18(1):5
- Article: NATURE MEDICINE. 2021;27(1):28-33
- Article: FRONTIERS IN IMMUNOLOGY. 2021;12:727300
- Article: MED. 2020;1(1):14-20
- Article: SCIENTIFIC REPORTS. 2020;10(1):20425
- Article: CELL. 2020;183(4):968-981.e7
- Article: SCIENCE. 2020;370(6515):eabd4585
- Article: SCIENCE. 2020;370(6515):eabd4570
- Article: NATURE COMMUNICATIONS. 2020;11(1):4487
- Article: CELL REPORTS MEDICINE. 2020;1(5):100078
- Article: CELL REPORTS. 2020;32(3):107923
- Article: GENOME MEDICINE. 2020;12(1):25
- Article: SCIENCE. 2019;366(6472):eaax9198
- Article: PLOS BIOLOGY. 2019;17(10):e3000383
- Article: ELIFE. 2019;8:e43578
- Article: JCI INSIGHT. 2019;4(9):126492
- Article: NATURE MEDICINE. 2019;25(4):591-596
- Article: JCI INSIGHT. 2019;4(3):e125442
- Article: EBIOMEDICINE. 2019;40:517-527
- Article: METHODS IN MOLECULAR BIOLOGY. 2019;1989:111-123
- Article: METHODS IN MOLECULAR BIOLOGY. 2019;1913:33-48
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2019;89(1):e12732
- Article: CELL. 2018;174(5):1277-1292.e14
- Article: CLINICAL IMMUNOLOGY. 2018;193:70-79
- Article: CELL METABOLISM. 2018;27(2):378-392.e5
- Article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2018;5:81
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(3):135-142
- Article: CELL REPORTS. 2017;20(9):2238-2250
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(30):E6097-E6106
- Article: NATURE COMMUNICATIONS. 2017;8:15627
- Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1130
- Article: FRONTIERS IN IMMUNOLOGY. 2017;8:717
- Article: HAEMATOLOGICA. 2015;100(11):1477-1485
- Article: CELL. 2015;160(1-2):37-47
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(1):202-207
- Article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2013;9(4):307-317
- Article: FRONTIERS IN IMMUNOLOGY. 2013;4:65
- Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2012;96(6):798-800
- Article: ONCOGENESIS. 2012;1(3):e3
- Article: JOURNAL OF IMMUNOLOGY. 2012;188(5):2218-2226
- Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2011;131(7):1521-1529
- Article: PLOS ONE. 2010;5(10):e13174
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(4):1553-1558
- Article: JOURNAL OF NEUROSCIENCE. 2009;29(43):13503-13515
- Article: PLOS ONE. 2009;4(6):e6046
- Article: IMMUNITY. 2009;30(3):337-347
- Article: BLOOD. 2009;113(11):2434-2441
- Article: JOURNAL OF IMMUNOLOGY. 2009;182(3):1460-1468
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):2934-2937
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(1):1-11
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(1):30-36
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All other publications
- Corrigendum: NATURE. 2024;634(8033):E5
- Preprint: BIORXIV. 2024
- Preprint: RESEARCH SQUARE. 2024
- Editorial comment: TRENDS IN MOLECULAR MEDICINE. 2024;30(3):200-201
- Preprint: BIORXIV. 2024
- Corrigendum: GENOME MEDICINE. 2024;16(1):6
- Review: NATURE REVIEWS GASTROENTEROLOGY AND HEPATOLOGY. 2024;21(1):35-45
- Conference publication: 2023;00:715-720
- Review: SEMINARS IN IMMUNOLOGY. 2023;69:101794
- Review: TRENDS IN IMMUNOLOGY. 2023;44(8):577-584
- Preprint: BIORXIV. 2023
- Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;151(4):818-831
- Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;151(4):832-840
- Editorial comment: SCIENCE. 2023;379(6632):538-539
- Conference publication: ARTHRITIS & RHEUMATOLOGY. 2023;75:4913-4915
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Review: CAMBRIDGE PRISMS: PRECISION MEDICINE. 2023;1:e25
- Editorial comment: THE BMJ. 2022;379:o2750
- Editorial comment: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(7):1354-1359
- Letter: THE LANCET GASTROENTEROLOGY AND HEPATOLOGY. 2022;7(7):594-595
- Review: SCIENCE. 2022;376(6596):945-950
- Letter: NATURE MEDICINE. 2022;28(5):879-882
- Preprint: BIORXIV. 2022
- Review: NATURE. 2022;603(7902):587-598
- Preprint: RESEARCH SQUARE. 2022
- Review: IMMUNITY. 2022;55(2):201-209
- Corrigendum: NATURE IMMUNOLOGY. 2022;23(2):341
- Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(1):96-98
- Review: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2021;218(6):e20210446
- Editorial comment: NATURE METHODS. 2021;18(6):588-591
- Editorial comment: JOURNAL OF CLINICAL IMMUNOLOGY. 2020;40(7):958-959
- Editorial comment: CURRENT OPINION IN IMMUNOLOGY. 2020;65:iv
- Review: CURRENT OPINION IN IMMUNOLOGY. 2020;65:28-31
- Preprint: BIORXIV. 2020
- Editorial comment: CELL. 2020;181(6):1194-1199
- Review: HUMAN GENETICS. 2020;139(6-7):795-799
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2020;109(6):1082-1083
- Editorial comment: CELL. 2020;180(5):820-821
- Review: JAMA PEDIATRICS. 2019;173(11):1032-1040
- Editorial comment: NATURE MEDICINE. 2019;25(7):1026
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2019;108(7):1357-1358
- Letter: IMMUNITY. 2019;50(6):1335-1336
- Review: THE FEBS JOURNAL. 2019;286(8):1514-1522
- Editorial comment: NATURE REVIEWS IMMUNOLOGY. 2019;19(2):87-88
- Review: ANNUAL REVIEW OF IMMUNOLOGY. 2018;36:843-864
- Editorial comment: CELL HOST AND MICROBE. 2017;21(3):309-310
- Review: NATURE REVIEWS IMMUNOLOGY. 2017;17(1):21-29
- Review: TRENDS IN IMMUNOLOGY. 2016;37(3):233-243
- Editorial comment: IMMUNITY. 2015;43(6):1035-1037
- Thesis / dissertation: 2011
- Review: NATURE REVIEWS IMMUNOLOGY. 2010;10(10):724-734
- Review: TRENDS IN IMMUNOLOGY. 2009;30(4):143-149
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Grants
- Deutsche Forschungsgemeinschaft1 January 2024
- Swedish Research Council1 January 2023 - 31 December 2027
- Swedish Research Council1 December 2022 - 30 November 2025
- Barncancerfonden1 January 2022 - 31 December 2022
- Swedish Research Council1 December 2021 - 30 November 2024
- Swedish Research Council1 June 2021 - 31 May 2024
- Swedish Research Council1 January 2021 - 31 December 2023
- Swedish Research Council1 January 2021 - 31 December 2024
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2021
- Swedish Cancer Society1 January 2021
- Swedish Research Council1 January 2020 - 31 December 2023
- Knut and Alice Wallenberg Foundation1 January 2020 - 1 January 2025
- Swedish Research Council1 January 2019 - 31 December 2021
- Swedish Research Council1 December 2018 - 30 November 2023
- ISAC - Immune System Against Cancer in Children: A New Platform for Increased Knowledge of the Immune System in Children with Cancer, Aiming to Accelerate the Introduction of ImmunotherapySwedish Cancer Society1 January 2018
- The maturation of a well-balanced immune system determines the prognosis for patients with leukemia who undergo stem cell transplantation.Swedish Cancer Society1 January 2017
- The maturation of a well-balanced immune system determines the prognosis for patients with leukemia who undergo stem cell transplantation.Swedish Cancer Society1 January 2016
- The maturation of a well-balanced immune system determines the prognosis for patients with leukemia who undergo stem cell transplantation.Swedish Cancer Society1 January 2015
Employments
- Professor/Specialist Physician, Department of Women's and Children's Health, Karolinska Institutet, 2021-
Degrees and Education
- Docent, Karolinska Institutet, 2018
- Degree Of Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2011
- University Medical Degree, Karolinska Institutet, 2010
Distinction and awards
- Wallenberg Scholar, Knut and Alice Wallenberg Foundation, 2024
- VR Consolidator award, Swedish Research Council, 2022
- SSMF Consolidator award, Swedish Society for Medical Research, 2022
- Göran Gustavsson award, Royal Swedish Academy of Sciences, 2019
- EMBO Young Investigator, European Molecular Biology Organization, 2019
- Wallenberg Academy Fellow, Knut and Alice Wallenberg Foundation, 2019
- Jonas Söderquist Scholarship, 2019
- Member, Young Academy of Sweden, 2019
- The Sven and Ebba-Christina Hagberg Prize, By the Sven and Ebba-Christina Hagberg foundation, 2018
- Wallenberg Clinical Fellow, Marianne and Marcus Wallenberg Foundation, 2017
- ERC starting grant, European Research Council, 2015
- VR young researcher grant, Swedish Research Council, 2015
- SSMF young researcher grant, Swedish Society for Medical Research, 2014
- Wenner-Gren Fellow, 2012
- Prins Bertil's award, Sweden America Foundation, 2012
- Doktorsexamen, 2009
Supervisor
- Hanna Danielsson, The role of early-life events on protein expression and gut microbiome in extreme preterm infants, 2020
Visiting research fellowships
- Postdoc, Stanford University School of Medicine, 2012-2013