Development, transcription factors, neurons, dopamine – Thomas Perlmann's Group

Our group is interested in how specific cell types of the central nervous system are generated and how they are maintained.

Our research

We are mostly focusing on neurons using dopamine as neurotransmitter and we are unraveling the signaling and transcriptional regulation that govern the specification, differentiation and maintenance of these cells. The studies have resulted in the identification of several transcription factors with key roles in these processes. The projects are focused on understanding functions in both early specification events and in maintenance of dopamine neurons in the adult brain. Moreover, we are also interested in regenerative medicine in relation to Parkinson’s disease and other brain disorders.


Selected publications

Staff and contact

Group leader

All members of the group