Thomas Perlmann

Thomas Perlmann

Professor
Visiting address: Solnavägen 9, 17165 Stockholm
Postal address: C5 Cell- och molekylärbiologi, C5 CMB Perlmann, 171 77 Stockholm
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About me

  • Professor in Molecular Developmental Biology

    My research group is localized at the department of Cell and Molecular Biology and at the Stockholm Branch of the Ludwig Institute for Cancer Research, where I am also the director.

    Education
    - Ph.D., Karolinska Institutet, 1991
    - M.Sc., Stockholm University, Chemistry and Biology, 1987

    Academic honours, awards and prizes
    - 2011 Nicholson Lecturer award at Rockefeller Rockefeller University
    - 2008 Member of the Royal Academy of Sciences, Sweden
    - 2006 Member of the Nobel Assembly, Karolinska Institutet

    1999 Göran Gustafsson Prize in Molecular Biology

    1997 Eric K. Fernström, Young Investigator Prize

Research

  • The vast complexity of the central nervous system raises challenging questions concerning the specification and differentiation of specific types of neurons. Dopamine neurons are clinically important cells that degenerate in patients with Parkinson’s disease and are also implicated in other neurological and psychiatric conditions.

    My group is interested in unraveling the signaling and transcriptional regulation that govern the specification, differentiation and maintenance of these cells. The studies have resulted in the identification of several transcription factors with key roles in these processes. The projects are focused on understanding functions in both early specification events and in maintenance of dopamine neurons in the adult brain. Moreover, we are also interested in regenerative medicine in relation to Parkinson’s disease and other brain disorders.

Selected publications

Articles

All other publications

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