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Martin Hällberg's Group

Structural basis of RNA biogenesis

We want to understand, on a molecular level, how proteins and RNA recognize each other and how their interaction interface mediates specificity. To this end we study both apo-structures and RNA co-crystal structures of proteins involved in processing and modification of RNA. Most transcripts undergo processing and modification. Out of these, transfer RNA is by far the most studied and modification of tRNA has been the focus of our lab for several years. Recently, we have expanded into structural studies on the general process of mitochondrial RNA biogenesis: transcription, processing and modification.

Group members

Martin Hällberg, Senior Researcher

Linda Reinard, Associated

Saba Shahzad, PhD student, Graduate Student

Sagar Sridhara, PhD student, Graduate Student

Agnes Zimmer, Associated

Selected Publications

26319014

25953853

25690892

25088301

22949673