Nils-Göran Larsson Group
The mitochondrion is a key player in cellular function and dysfunctional mitochondria have been implicated in a number of disorders as well as in the process of normal ageing. Our knowledge of mitochondria is, however, still limited. How is the number and the funciton of mitochondra regulated? What happens in a cell with dysfunctional mitochondria?
- Production and analysis of genetically modified mouse models
- Methods in molecular biology such as analysis of DNA, RNA and proteins.
- Swedish Research Council
- Knut and Alice Wallenberg Foundation
Members of the group
|Camilla Koolmeister||Research coordinator|
|Eva Berglund||Research coordinator|
|Nils-Göran Larsson||Professor/senior physician|
|Seungmin Lee||Assistant professor|
|Susanne Virding||Biomedical scientist|
SLIRP stabilizes LRPPRC via an RRM-PPR protein interface.
Nucleic Acids Res. 2016 Aug;44(14):6868-82
POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.
Sci Adv 2016 Aug;2(8):e1600963
Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.
Cell Rep 2016 Aug;16(7):1874-90