ERC funding at KI
The main goal of the European Research Council (ERC) is to encourage high-quality research in Europe through competitive funding.
ERC Synergy Grants
ERC Synergy Grants, worth up to 10 million EUR, aim to bring together 2-4 outstanding scientists at the forefront of complementary fields to jointly undertake bold, curiosity-driven research with the potential to transform the research landscape.
András Simon – SALAMANDRA; Decoding the organization and regeneration of locomotor neuronal networks in tetrapods by integrating genomics, systems neuroscience, numerical modeling, and biorobotics
Collaboration with Auke Ijspeert at École polytechnique fédérale de Lausanne in Switzerland and Dimitri Ryczko at Université de Sherbrooke in Canada.
More at KI News
Mikael Rydén – SPHERES; Lipid droplet hypertrophy: the link between adipocyte dysfunction and cardiometabolic diseases
Collaboration with Bruno Antonny at CNRS in France and Dominique Langin (corresponding PI) at the Université Paul Sabatier in France.
Igor Adameyko and Susanne Schlisio – KILL-OR-DIFFERENTIATE; Using cell-cell interactions to unlock new cancer treatments
(Igor Adameyko (corresponding PI) is also affiliated to MedUni Vienna in Austria.) Collaboration with Peter Kharchenko at the Harvard Medical School in the US and Olivier Delattre at the Institut Curie in France.
ERC Advanced Grants
ERC Advanced Grants, worth up to 2.5 million EUR over a period of five years, allow exceptional established research leaders of any nationality and any age to pursue ground-breaking, high-risk projects that open new directions in their respective research fields or other domains. The ERC Advanced Grant funding targets researchers who have already established themselves as independent research leaders in their own right. At KI the following researchers have received an ERC Advanced Grant(s):
- Patrik Ernfors – Descending control of pain.
- Ernest Arenas – PreciseCellPD; A precision cell-replacement strategy for Parkinson's Disease
- Per-Olof Berggren (second grant) – EYELETS; A regenerative medicine approach in diabetes
- Henrik Ehrsson – SELF-UNITY; The Unity of the Bodily Self
- Gunilla Karlsson Hedestam – IMMUNEDIVERSITY; Defining human adaptive immune gene diversity and its impact on disease
- Kenneth R. Chien – 5D Heart Patch; A Functional, Mature In vivo Human Ventricular Muscle Patch for Cardiomyopathy.
- Patrik Ernfors (second grant) – PainCells; Decomposition of pain into cell types.
- Magnus Ingelman-Sundberg – HEPASPHER; Mimicking liver disease and regeneration in vitro for drug development and liver transplantation.
- Nils-Göran Larsson (second grant, moved from Max Planck Institute) – mtDNA-CURE; Treating mitochondrial disease caused by pathogenic mtDNA mutations
- Jonas Frisén (second grant) – Exploration and promotion of neurogenesis in the adult brain
- Thomas Helleday – Targeting oxidative repair proteins for treatment of cancer and inflammation
- Ole Kiehn (second grant) – Functional deciphering of the integrated brainstem connectome that selects locomotor behavior
- Klas Wiman – Restoration of tumor suppressor function by induction of translational read-through of premature termination codons - a strategy for improved cancer therapy
- Per-Olof Berggren – An in vivo imaging approach to understand pancreatic beta-cell signal-transduction
- Carlos Ibanez (second grant) – Understanding death-receptor signaling and physiology in the nervous system
- Christer Betsholtz – Mechanisms of regulation of the blood-brain barrier
- Lars Olson – Plasticity and formation of lasting memories in health and disease
- Jonas Frisén – Neurogenesis in the adult human brain
- Ole Kiehn – Linking glutamatergic spinal cord and brainstem neuronal circuits to the control of locomotor behavior
- Thomas Helleday – GEnetic NEtworks as a tool for anti-CAncer Drug Development
- Lars Klareskog – Genes, environment and immunity in the pathogenesis of rheumatoid arthritis
- Yihai Cao – New mechanisms of angiogenesis modulators in switching between white and brown tissue
- Patrik Ernfors – Identification of new mechanism of stem cell self-renewal
- Carlos Ibanez – Metabolic control by the TGF-x superfamilt receptor ALK7
- Jussi Taipale – Dissecting the transcriptional mechanisms controlling growth during normal development and cancer
- Juleen Zierath – Discovery of type 2 diabetes targets
ERC Consolidator Grants
ERC Consolidator Grants, worth up to 2 mEuro, are designed to support researchers at the stage at which they are consolidating their own independent research team or programme. The scheme will strengthen independent and excellent new individual research teams that have been recently created. At KI the following researchers have received an ERC Consolidator Grant:
Ulrika Marklund – Dissecting a stepwise principle of cellular diversification to instruct regeneration in the enteric nervous system (divENSify).
- Samir El Andaloussi – Release of engineered Extracellular vesicles for delivery of Biotherapeutics
- Camilla Svensson -- Autoantibodies and chronic pain - Unraveling new mechanisms contributing to pain in rheumatic disease
- Myriam Aouadi -- Revealing the contribution of liver macrophage populations to NASH in insulin resistance
- Jens Hjerling Leffler – Brain cell type-specific interactions and schizophrenia
- Anna Rising – Novel approaches to the generation of artificial spider-silk super fibers
- Maja Jagodic – Epi4MS – targeting the epigenome for a better understanding of disease pathogenesis and novel therapeutic strategies in Multiple Sclerosis
- Olov Andersson – In vivo drug discovery for cellular reprogramming to β-cells; towards a future regenerative therapy for diabetes (Reprogram-Diabetes)
- Anca Catrina – Towards prevention of autoimmune diseases; the case of rheumatoid arthritis (PREVENT RA)
- Björn Högberg – Cellular Position Tracking Using DNA Origami Barcodes (CellTrack)
- Gonçalo Castelo-Branco – Reversing the epigenetic state of oligodendrocyte precursors cells in multiple sclerosis (EPIScOPE )
- Weimin Ye – Understanding microbe-induced stomach cancer; the key to a workable strategy for worldwide prevention
- Rickard Sandberg – Revealing allele-level regulation and dynamics using single-cell gene expression analyses
- Per Svenningsson – Prosaposin and GPR37 in synucleinopathies
ERC Starting Grants
ERC Starting Grants, worth up to 1.5 million Euro for during av five year period, aim to support up-and-coming research leaders who are about to establish a proper research team and to start conducting independent research in Europe. The scheme targets promising researchers who have the proven potential of becoming independent research leaders. It will support the creation of excellent new research teams. At KI the following researchers have received an ERC Starting Grant:
- Niklas Björkström – Dissecting tissue-resident lymphocyte homeostasis in humans (RESIDE)
- Janina Seubert – Olfaction as the link between flavour preference formation and retrieval during food consumption (OLFLINK)
- Nils Landegren – Deciphering sex differences in the human immune system (SEXimmune)
- Jenny Mjösberg – Single-cell analysis of intestinal lymphocytes reveals targets for treatment of inflammatory bowel disease (GUT-SEQ).
- Maria Genander – Redefining the esophageal stem cell niche – towards targeting of squamous cell carcinoma (TroyCAN)
- Pia Dosenovic – Vaccine development against variable pathogens (VIVA).
Fang Fang – Unraveling the Interplay between Metabolism, Gut Microbiome and Adaptive Immunity in Amyotrophic Lateral Sclerosis (MegaALS).
- Erik Melén – Biomarkers for respiratory disease
- Georgios Sotiriou – Fighting infections and antimicrobial resistance with nanoengineering
- Magda Bienko – Illuminating GENome Organization through integrated MIcroscopy and Sequencing
- Simon Elsässer – Chromatin dynamics resolved by rapid protein labeling and bioorthogonal capture
- Anna Wredenberg – Mitochondrial methylation and its role in health and disease
- Petter Brodin – Shaping of the human immune system by primal environmental exposures in the newborn child
- Lars Maegdefessel – Therapeutic and biomarker potential of long non-coding RNAs in vascular disease
- Marie Carlén – The role of parvalbumin in interneurons in cognition and behaviour
- Erik Ingelsson (now at Uppsala university)
- Pontus Boström – Irisin - a novel myokine protective against metabolic disease (has since left KI)
- Yenan Bryceson – Next-generation sequencing for detection of human primary immunodeficiency syndromes
- Christian Göritz – The role of pericytes in central nervous system scarring and fibrosis
- Kristian Pietras – Exploring the tumor as a communicating organ (now at Lund university)
- Tomas Renné – Factor XII and the contact system: cross-talk between thrombosis and inflammation (has since left KI)
- Andreas Olsson – Emotional learning in social interaction
- Gilad Silberberg – Sensory integration in the striatal microcircuit
- Andras Simon – Novel strategies for brain regeneration
- Christian Broberger – Network principles of neuroendocrine control
- Luca Jovine – Molecular basis of mammalian egg-sperm interaction
- Sten Linnarsson – Charting the landscape of brain development
- Kirsty Spalding – Adipose tissue mass regulation in lean and obese individuals
- Qiang Pan-Hammarström – Switch recombination: A model for DNA editing and repair in human lymphocytes
- Rickard Sandberg – Single-cell gene regulation in differentiation and pluripotency
ERC Proof of Concept
The "Proof of Concept" ERC funding scheme is open to researchers who have already been awarded an ERC grant. The grant is worth up to 150.000 Euro. ERC grant holders can apply for this additional funding to establish the innovation potential of ideas arising from their ERC-funded frontier research projects. At KI the following researchers have received an ERC Proof of Concept:
- Simon Elsässer – Highly multiplexed, quantitative protein biomarker profiling (hmqPro)
- Björn Högberg – Single-molecule reconstruction for high-throughput, short-read sequencing technologies (FuseSeq)
- Anna Rising – Artificial spider silk textiles (ArtSilkTex)
News article: They are awarded ERC Proof of Concept Grants
- Georgios Sotiriou – Hybrid drug-loaded plasmonic photothermal microneedle patch against skin infections (HOTSKIN)
News article: ERC awards medical device to fight lethal skin infections
- Simon Elsässer – Highly multiplexed, quantitative epigenetic profiling (hmqChIP)
News article: KI-researcher awarded with ERC Proof of Concept Grant 2020
- Thomas Helleday – Development of small molecule OGG1 Inhibitor and proof of concept in bleomycin-induced disease model of Inflammation and pulmonary Fibrosis (DOIIF)
News article: A new treatment for severe pneumonia and fibrosis
- Per-Olof Berggren – Validation of an in vivo translational medicine approach for the treatment of diabetes and diabetes complications
- Thomas Helleday – Novel viral therapy through targeting DNA repair (NOVITREP)
- Thomas Helleday – Commercializing first-in-class dCTPase Inhibitors for treatment of hematological Cancers
- Patrik Ernfors – Validation of a conceptually new treatment for glioblastoma multiforme
- Thomas Helleday – Proof of concept use of MTH1 inhibitors as new treatments for cancer
- Lars Klareskog – Prevent Rheumatoid Arthritis in Practice