Lu Yi

Lu Yi

Principal Researcher
E-mail: lu.yi@ki.se
Telephone: +46852487772
Visiting address: Nobelsvägen 12a, 17165 SOLNA
Postal address: C8 Medicinsk epidemiologi och biostatistik, C8 MEB I Lu, 171 77 Stockholm

About me

  • I am a Principal Researcher at Karolinska Institutet (KI), Sweden. I lead a research group conducting psychiatric genetics research, especially in major depressive disorder (MDD). I am directing the KI Psychiatric Genomics Institute and co-leading the Nordic Tryggve consortium.

    My research involves integrating large-scale genomic data and nationwide electronic healthcare records to investigate depression subtypes, as a way to reduce the substantial heterogeneity in this disorder. My long-term research vision is to promote targeted drug development and treatment optimization for MDD patient subgroups to achieve precision psychiatry.

    My research excellence has been recognised nationally and internationally, for which I have been awarded many prestigious grants including a recent award of €1.5 million from European Research Council. I am also the Sweden PI on major funding from US-NIH and EU-Horizon2020.

Research

  • 1. Genetics of major depressive disorder and its subtypes
    MDD is heterogeneous: however, the extent to which genetic factors distinguish patient subgroups (genetic heterogeneity) remains uncertain. We
    therefore seek evidence for genetic heterogeneity in MDD by studying patient subgroups. In particular, we focus on patients who are most severely ill ("extreme MDD"). I am also a key analyst in the Psychiatric Genomics Consortium MDD working group.

    2. Trans-Nordic collaboration of “register genomics” in psychiatry
    I have co-led the Nordic Tryggve consortium since 2018 (Tryggve: trans-Nordic collaboration on register and genomics research in psychiatry). The Tryggve consortium has enabled integration of genetics in population-based psychiatric studies in Sweden, Denmark, and Norway. We have achieved comprehensive harmonization of software, data processing pipelines, and register phenotype and genomic data using singularity containers. Altogether, these allow us to analyze Nordic register and genomic data in a unified scheme where we ask empirical questions and get rapid, secure, and reproducible answers.

    3. Genetic risk factors of other complex disorders
    I led and contributed to many genome-wide association studies on complex traits and diseases of medical importance, including cancers, eye diseases, and allergic diseases. These work have been published in leading genetic journals, including three in Nature Genetics.

    *My research are proudly supported by:*
    KI Consolidator Grant 2023, *PI.* 2024-2028
    SfoEpi Consolidator Grant 2023, *PI.* 2023-2026 (withdrawn upon the recipient of the KI consolidator grant)
    European Research Council Starting Grant 2021, *PI.* 2022-2027.
    KI Faculty-funded career position as *Senior Researcher.* 2022-2024.
    Swedish Research Council. *PI.* 2022-2026.
    European Union's Horizon 2020. Grant No 964874. *Sub-award PI*. 2021-2025.
    NIH/NIMH R01 MH123724. *Co-PI/Sub-award PI*. 2020-2025.
    KI Faculty-funded career position as *Assistant Professor.* 2018-2022.
    StratNeuro Start Up Award, KI Neuroscience, 2019-2020.
    2018 NARSAD Young Investigator Award, Brain &

  • Behavior Research Foundation, USA. 2019-2021.
    KI Research Foundation. 2018-2019.
    Assistant professor, funded by the Department of Medical Epidemiology and Biostatistics (rank #1). 2018-2022
    NHMRC Early Career Fellowship (CJ Martin - Overseas Biomedical Fellowship). Australian Government. 2015-2018
    Australian delegate of early career researcher at the 64th Nobel Laureates Meeting (Physiology or Medicine). Australian Academy of Science 2014

Teaching

  • SUPERVISION:
    Research specialist Tong Gong
    Postdoc: Shengxin Liu, Thi Thuy Dung Nguyen, Joelle Pasman.
    PhD student Ying Xiong. "Genetic epidemiology of treatment-resistant depression", since 2021. As main supervisor.
    PhD student Arvid Harder. "Genomics and treatment outcomes of major depressive disorder subtypes", since 2023. As main supervisor.
    *Former students*
    PhD student Thi Thuy Dung Nguyen. “Aetiology and outcomes in psychiatric disorders”, As main supervisor. (Defended thesis 2023.12.15)
    PhD student Jet Termorshuizen. “Genetic and environmental factors influencing the course and outcome of eating disorder”, As co-supervisor. (Defended thesis 2023.12.08)
    PhD student Ashley Thompson. “Prediction of negative life outcomes in children with ADHD”. As co-supervisor. (Defended thesis 2022.02.18)
    Bachelor student Alison Baxley, Bachelor Thesis in Medical Science with a Major in Biomedicine, Karolinska Institutet. “Polygenic risk scores for
    schizophrenia and childhood accidents, injury and self-harm”. Spring 2017.

    TEACHING:
    Lecturer: "Psychiatric Genetics" within the Research School of Psychiatry (Forskarskolan inom klinisk psykiatri), Karolinska Institutet and Region
    Stockholm. Feb 6-10, 2023.
    Course: “Molecular genetic psychiatry”. Clinical Psychology program, Karolinska Institutet. 2017, 2018, 2019.
    Course: “Molecular epidemiology”. Epidemiology program, Karolinska Institutet. 2018, 2020.
    Summer school: “GWAS and imputation”, Brain Imaging Genetics Summer School, Nijmegen, the Netherlands. 2018.

Articles

  • Article: JAMA PSYCHIATRY. 2024;81(6):579-585
    Simonsson O; Mosing MA; Osika W; Ullén F; Larsson H; Lu Y; Wesseldijk LW
  • Article: NATURE GENETICS. 2024;56(5):792-808
    Nievergelt CM; Maihofer AX; Atkinson EG; Chen C-Y; Choi KW; Coleman JRI; Daskalakis NP; Duncan LE; Polimanti R; Aaronson C; Amstadter AB; Andersen SB; Andreassen OA; Arbisi PA; Ashley-Koch AE; Austin SB; Avdibegoviç E; Babić D; Bacanu S-A; Baker DG; Batzler A; Beckham JC; Belangero S; Benjet C; Bergner C; Bierer LM; Biernacka JM; Bierut LJ; Bisson JI; Boks MP; Bolger EA; Brandolino A; Breen G; Bressan RA; Bryant RA; Bustamante AC; Bybjerg-Grauholm J; Bækvad-Hansen M; Børglum AD; Børte S; Cahn L; Calabrese JR; Caldas-de-Almeida JM; Chatzinakos C; Cheema S; Clouston SAP; Colodro-Conde L; Coombes BJ; Cruz-Fuentes CS; Dale AM; Dalvie S; Davis LK; Deckert J; Delahanty DL; Dennis MF; Desarnaud F; DiPietro CP; Disner SG; Docherty AR; Domschke K; Dyb G; Kulenović AD; Edenberg HJ; Evans A; Fabbri C; Fani N; Farrer LA; Feder A; Feeny NC; Flory JD; Forbes D; Franz CE; Galea S; Garrett ME; Gelaye B; Gelernter J; Geuze E; Gillespie CF; Goleva SB; Gordon SD; Goçi A; Grasser LR; Guindalini C; Haas M; Hagenaars S; Hauser MA; Heath AC; Hemmings SMJ; Hesselbrock V; Hickie IB; Hogan K; Hougaard DM; Huang H; Huckins LM; Hveem K; Jakovljević M; Javanbakht A; Jenkins GD; Johnson J; Jones I; Jovanovic T; Karstoft K-I; Kaufman ML; Kennedy JL; Kessler RC; Khan A; Kimbrel NA; King AP; Koen N; Kotov R; Kranzler HR; Krebs K; Kremen WS; Kuan P-F; Lawford BR; Lebois LAM; Lehto K; Levey DF; Lewis C; Liberzon I; Linnstaedt SD; Logue MW; Lori A; Lu Y; Luft BJ; Lupton MK; Luykx JJ; Makotkine I; Maples-Keller JL; Marchese S; Marmar C; Martin NG; Martínez-Levy GA; McAloney K; McFarlane A; McLaughlin KA; McLean SA; Medland SE; Mehta D; Meyers J; Michopoulos V; Mikita EA; Milani L; Milberg W; Miller MW; Morey RA; Morris CP; Mors O; Mortensen PB; Mufford MS; Nelson EC; Nordentoft M; Norman SB; Nugent NR; O'Donnell M; Orcutt HK; Pan PM; Panizzon MS; Pathak GA; Peters ES; Peterson AL; Peverill M; Pietrzak RH; Polusny MA; Porjesz B; Powers A; Qin X-J; Ratanatharathorn A; Risbrough VB; Roberts AL; Rothbaum AO; Rothbaum BO; Roy-Byrne P; Ruggiero KJ; Rung A; Runz H; Rutten BPF; de Viteri SS; Salum GA; Sampson L; Sanchez SE; Santoro M; Seah C; Seedat S; Seng JS; Shabalin A; Sheerin CM; Silove D; Smith AK; Smoller JW; Sponheim SR; Stein DJ; Stensland S; Stevens JS; Sumner JA; Teicher MH; Thompson WK; Tiwari AK; Trapido E; Uddin M; Ursano RJ; Valdimarsdóttir U; Van Hooff M; Vermetten E; Vinkers CH; Voisey J; Wang Y; Wang Z; Waszczuk M; Weber H; Wendt FR; Werge T; Williams MA; Williamson DE; Winsvold BS; Winternitz S; Wolf C; Wolf EJ; Xia Y; Xiong Y; Yehuda R; Young KA; Young RM; Zai CC; Zai GC; Zervas M; Zhao H; Zoellner LA; Zwart J-A; deRoon-Cassini T; van Rooij SJH; van den Heuvel LL; AURORA Study; Estonian Biobank Research Team; FinnGen Investigators; HUNT All-In Psychiatry; Stein MB; Ressler KJ; Koenen KC
  • Article: INFLAMMATORY BOWEL DISEASES. 2024;:izae027
    Gong T; Brew BK; Lundholm C; Smew AI; Harder A; Kuja-Halkola R; Ludvigsson JF; Lu Y; Almqvist C
  • Article: MOLECULAR PSYCHIATRY. 2024;:1-10
    Song J; Jonsson L; Lu Y; Bergen SE; Karlsson R; Smedler E; Gordon-Smith K; Jones I; Jones L; Craddock N; Sullivan PF; Lichtenstein P; Di Florio A; Landén M
  • Article: MOLECULAR GENETICS & GENOMIC MEDICINE. 2023;11(12):e2255
    Li X; Ploner A; Wang Y; Mak JKL; Lu Y; Magnusson PKE; Jylhävä J; Hägg S
  • Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(12):884-895
    Guintivano J; Byrne EM; Kiewa J; Yao S; Bauer AE; Aberg KA; Adams MJ; Campbell A; Campbell ML; Choi KW; Corfield EC; Havdahl A; Hucks D; Koen N; Lu Y; Mægbæk ML; Mullaert J; Peterson RE; Raffield LM; Sallis HM; Sealock JM; Walker A; Watson HJ; Xiong Y; Yang JMK; Anney RJL; Gordon-Smith K; Hubbard L; Jones LA; Mihaescu R; Nyegaard M; Pardiñas AF; Perry A; Saquib N; Shadyab AH; Viktorin A; Andreassen OA; Bigdeli TB; Davis LK; Dennis C-L; Di Florio A; Dubertret C; Feng Y-CA; Frey BN; Grigoriadis S; Gloaguen E; Jones I; Kennedy JL; Krohn H; Kunovac Kallak T; Li Y; Martin NG; McIntosh AM; Milgrom J; Munk-Olsen T; Oberlander T; Olsen CM; Ramoz N; Reichborn-Kjennerud T; Robertson Blackmore E; Rubinow D; Skalkidou A; Smoller JW; Stein DJ; Stowe ZN; Taylor V; Tebeka S; Tesli M; Van Lieshout RJ; van den Oord EJCG; Vigod SN; Werge T; Westlye LT; Whiteman DC; Zar HJ; Major Depressive Disorder Working Group of the Psy; Wray N; Meltzer-Brody S; Sullivan P
  • Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(10):714-722
    Nguyen T-D; Kowalec K; Pasman J; Larsson H; Lichtenstein P; Dalman C; Sullivan PF; Kuja-Halkola R; Lu Y
  • Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):301
    Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Sigström R; Jonsson L; Clements CC; Andersson E; Boberg J; Lewis CM; Sullivan PF; Landén M; Lu Y
  • Article: NEUROLOGY. 2023;101(5):e522-e532
    Kowalec K; Fitzgerald KC; Salter A; Dolovich C; Harder A; Bernstein CN; Bolton J; Cutter GR; Graff LA; Hägg S; Hitchon CA; Lu Y; Lublin F; McKay KA; Patten SB; Patki A; Tiwari HK; Wolinsky JS; Marrie RA
  • Article: AGING CELL. 2023;22(8):e13868
    Mak JKL; Kananen L; Qin C; Kuja-Halkola R; Tang B; Lin J; Wang Y; Jääskeläinen T; Koskinen S; Lu Y; Magnusson PKE; Hägg S; Jylhävä J
  • Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2023;38(7):809-819
    Qin C; Diaz-Gallo L-M; Tang B; Wang Y; Nguyen T-D; Harder A; Lu Y; Padyukov L; Askling J; Hägg S
  • Article: ECLINICALMEDICINE. 2023;61:102063
    Shen Q; Mikkelsen DH; Luitva LB; Song H; Kasela S; Aspelund T; Bergstedt J; Lu Y; Sullivan PF; Ye W; Fall K; Tornvall P; Pawitan Y; Andreassen OA; Buil A; Milani L; Fang F; Valdimarsdóttir U
  • Article: THE LANCET REGIONAL HEALTH - EUROPE. 2023;29:100621
    Pasman JA; Meijsen JJ; Haram M; Kowalec K; Harder A; Xiong Y; Nguyen T-D; Jangmo A; Shorter JR; Bergstedt J; Das U; Zetterberg R; Tate A; Lichtenstein P; Larsson H; Odsbu I; Werge T; Reichborn-Kjennerud T; Andreassen OA; Sullivan PF; Buil A; Tesli M; Lu Y
  • Article: ARCHIVES OF SEXUAL BEHAVIOR. 2023;52(3):1213-1228
    Oginni OA; Lim KX; Purves KL; Lu Y; Johansson A; Jern P; Rijsdijk FV
  • Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):15
    Wesseldijk LW; Lu Y; Karlsson R; Ullén F; Mosing MA
  • Article: JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY. 2022;63(12):1513-1522
    Chen C; Lu Y; Lundström S; Larsson H; Lichtenstein P; Pettersson E
  • Article: MOLECULAR PSYCHIATRY. 2022;27(11):4453-4463
    Tielbeek JJ; Uffelmann E; Williams BS; Colodro-Conde L; Gagnon É; Mallard TT; Levitt BE; Jansen PR; Johansson A; Sallis HM; Pistis G; Saunders GRB; Allegrini AG; Rimfeld K; Konte B; Klein M; Hartmann AM; Salvatore JE; Nolte IM; Demontis D; Malmberg ALK; Burt SA; Savage JE; Sugden K; Poulton R; Harris KM; Vrieze S; McGue M; Iacono WG; Mota NR; Mill J; Viana JF; Mitchell BL; Morosoli JJ; Andlauer TFM; Ouellet-Morin I; Tremblay RE; Côté SM; Gouin J-P; Brendgen MR; Dionne G; Vitaro F; Lupton MK; Martin NG; COGA Consortium; Spit for Science Working Group; Castelao E; Räikkönen K; Eriksson JG; Lahti J; Hartman CA; Oldehinkel AJ; Snieder H; Liu H; Preisig M; Whipp A; Vuoksimaa E; Lu Y; Jern P; Rujescu D; Giegling I; Palviainen T; Kaprio J; Harden KP; Munafò MR; Morneau-Vaillancourt G; Plomin R; Viding E; Boutwell BB; Aliev F; Dick DM; Popma A; Faraone SV; Børglum AD; Medland SE; Franke B; Boivin M; Pingault J-B; Glennon JC; Barnes JC; Fisher SE; Moffitt TE; Caspi A; Polderman TJC; Posthuma D
  • Article: ELIFE. 2022;11:e80143
    Shen Q; Song H; Aspelund T; Yu J; Lu D; Jakobsdóttir J; Bergstedt J; Yi L; Sullivan P; Sjölander A; Ye W; Fall K; Fang F; Valdimarsdóttir U
  • Article: GENERAL HOSPITAL PSYCHIATRY. 2022;77:21-28
    Kowalec K; Salter A; Fitzgerald KC; Patel M; Han J; Lu Y; Bolton JM; Hitchon C; Bernstein CN; Patten S; Graff LA; Marriott JJ; Marrie RA; CIHR Team in Defining the Burden and Managing the
  • Article: JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY. 2022;61(7):934-945
    Jami ES; Hammerschlag AR; Ip HF; Allegrini AG; Benyamin B; Border R; Diemer EW; Jiang C; Karhunen V; Lu Y; Lu Q; Mallard TT; Mishra PP; Nolte IM; Palviainen T; Peterson RE; Sallis HM; Shabalin AA; Tate AE; Thiering E; Vilor-Tejedor N; Wang C; Zhou A; Adkins DE; Alemany S; Ask H; Chen Q; Corley RP; Ehli EA; Evans LM; Havdahl A; Hagenbeek FA; Hakulinen C; Henders AK; Hottenga JJ; Korhonen T; Mamun A; Marrington S; Neumann A; Rimfeld K; Rivadeneira F; Silberg JL; van Beijsterveldt CE; Vuoksimaa E; Whipp AM; Tong X; Andreassen OA; Boomsma DI; Brown SA; Burt SA; Copeland W; Dick DM; Harden KP; Harris KM; Hartman CA; Heinrich J; Hewitt JK; Hopfer C; Hypponen E; Jarvelin M-R; Kaprio J; Keltikangas-Järvinen L; Klump KL; Krauter K; Kuja-Halkola R; Larsson H; Lehtimäki T; Lichtenstein P; Lundström S; Maes HH; Magnus P; Munafò MR; Najman JM; Njølstad PR; Oldehinkel AJ; Pennell CE; Plomin R; Reichborn-Kjennerud T; Reynolds C; Rose RJ; Smolen A; Snieder H; Stallings M; Standl M; Sunyer J; Tiemeier H; Wadsworth SJ; Wall TL; Whitehouse AJO; Williams GM; Ystrøm E; Nivard MG; Bartels M; Middeldorp CM
  • Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2022;51(3):e108-e122
    Unnarsdóttir AB; Lovik A; Fawns-Ritchie C; Ask H; Kõiv K; Hagen K; Didriksen M; Christoffersen LAN; Garðarsson AB; McIntosh A; Kähler AK; Campbell A; Hauksdóttir A; Erikstrup C; Mikkelsen DH; Altschul D; Thordardottir EB; Frans EM; Kvale G; Tómasson G; Kariis HM; Jónsdóttir HL; Rúnarsdóttir H; Magnúsdóttir I; Eid J; Jakobsdóttir J; Nielsen KR; Kaspersen KA; Milani L; Trogstad L-IS; Yi L; Bruun MT; Sullivan PF; Magnus PM; Shen Q; Nesvåg R; Brandlistuen RE; Mägi R; Ostrowski SR; Løkhammer S; Solem S; Reichborn-Kjennerud T; Hansen TF; Werge T; Aspelund T; Porteous DJ; Fang F; Lehto K; Andreassen OA; Pedersen OBV; Hellard SL; Valdimarsdóttir UA
  • Article: MOLECULAR PSYCHIATRY. 2022;27(5):2439-2447
    Song J; Yao S; Kowalec K; Lu Y; Sariaslan A; Szatkiewicz JP; Larsson H; Lichtenstein P; Hultman CM; Sullivan PF
  • Article: MOLECULAR PSYCHIATRY. 2022;27(5):2514-2521
    Tate AE; Sahlin H; Liu S; Lu Y; Lundström S; Larsson H; Lichtenstein P; Kuja-Halkola R
  • Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):152
    Garcia-Argibay M; du Rietz E; Lu Y; Martin J; Haan E; Lehto K; Bergen SE; Lichtenstein P; Larsson H; Brikell I
  • Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):124
    Harder A; Nguyen T-D; Pasman JA; Mosing MA; Hägg S; Lu Y
  • Article: MOLECULAR PSYCHIATRY. 2022;27(3):1667-1675
    Nguyen T-D; Harder A; Xiong Y; Kowalec K; Hägg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan PF; Lu Y
  • Article: PLOS ONE. 2022;17(8):e0273116
    Neumann A; Nolte IM; Pappa I; Ahluwalia TS; Pettersson E; Rodriguez A; Whitehouse A; van Beijsterveldt CEM; Benyamin B; Hammerschlag AR; Helmer Q; Karhunen V; Krapohl E; Lu Y; van der Most PJ; Palviainen T; St Pourcain B; Seppälä I; Suarez A; Vilor-Tejedor N; Tiesler CMT; Wang C; Wills A; Zhou A; Alemany S; Bisgaard H; Bønnelykke K; Davies GE; Hakulinen C; Henders AK; Hyppönen E; Stokholm J; Bartels M; Hottenga J-J; Heinrich J; Hewitt J; Keltikangas-Järvinen L; Korhonen T; Kaprio J; Lahti J; Lahti-Pulkkinen M; Lehtimäki T; Middeldorp CM; Najman JM; Pennell C; Power C; Oldehinkel AJ; Plomin R; Räikkönen K; Raitakari OT; Rimfeld K; Sass L; Snieder H; Standl M; Sunyer J; Williams GM; Bakermans-Kranenburg MJ; Boomsma DI; van IJzendoorn MH; Hartman CA; Tiemeier H
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(13):2077-2084
    Harroud A; Marrie RA; Fitzgerald KC; Salter A; Lu Y; Patel M; Kowalec K
  • Article: HUMAN MOLECULAR GENETICS. 2021;30(19):1894-1905
    Beck JJ; Pool R; van de Weijer M; Chen X; Krapohl E; Gordon SD; Nygaard M; Debrabant B; Palviainen T; van der Zee MD; Baselmans B; Finnicum CT; Yi L; Lundström S; van Beijsterveldt T; Christiansen L; Heikkilä K; Kittelsrud J; Loukola A; Ollikainen M; Christensen K; Martin NG; Plomin R; Nivard M; Bartels M; Dolan C; Willemsen G; de Geus E; Almqvist C; Magnusson PKE; Mbarek H; Ehli EA; Boomsma DI; Hottenga J-J
  • Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2021;30(9):1669-1680
    Quinn MCJ; McCue K; Shi W; Johnatty SE; Beesley J; Civitarese A; O'Mara TA; Glubb DM; Tyrer JP; Armasu SM; Ong J-S; Gharahkhani P; Lu Y; Gao B; Patch A-M; Fasching PA; Beckmann MW; Lambrechts D; Vergote I; Velez Edwards DR; Beeghly-Fadiel A; Benitez J; Garcia MJ; Goodman MT; Dörk T; Dürst M; Modugno F; Moysich K; du Bois A; Pfisterer J; Bauman K; Karlan BY; Lester J; Cunningham JM; Larson MC; McCauley BM; Kjaer SK; Jensen A; Hogdall CK; Hogdall E; Schildkraut JM; Riggan MJ; Berchuck A; Cramer DW; Terry KL; Bjorge L; Webb PM; Friedlander M; Pejovic T; Moffitt M; Glasspool R; May T; Ene GEV; Huntsman DG; Woo M; Carney ME; Hinsley S; Heitz F; Fereday S; Kennedy CJ; Edwards SL; Winham SJ; deFazio A; Pharoah PDP; Goode EL; MacGregor S; Chenevix-Trench G; AGO Study Group; OPAL Study Group; for Australian Ovarian Cancer Study Group
  • Article: AGING CELL. 2021;20(9):e13459
    Atkins JL; Jylhävä J; Pedersen NL; Magnusson PK; Lu Y; Wang Y; Hägg S; Melzer D; Williams DM; Pilling LC
  • Article: MOLECULAR PSYCHIATRY. 2021;26(8):4487-4495
    Kowalec K; Lu Y; Sariaslan A; Song J; Ploner A; Dalman C; Hultman CM; Larsson H; Lichtenstein P; Sullivan PF
  • Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):413
    Ip HF; van der Laan CM; Krapohl EML; Brikell I; Sánchez-Mora C; Nolte IM; St Pourcain B; Bolhuis K; Palviainen T; Zafarmand H; Colodro-Conde L; Gordon S; Zayats T; Aliev F; Jiang C; Wang CA; Saunders G; Karhunen V; Hammerschlag AR; Adkins DE; Border R; Peterson RE; Prinz JA; Thiering E; Seppälä I; Vilor-Tejedor N; Ahluwalia TS; Day FR; Hottenga J-J; Allegrini AG; Rimfeld K; Chen Q; Lu Y; Martin J; Soler Artigas M; Rovira P; Bosch R; Español G; Ramos Quiroga JA; Neumann A; Ensink J; Grasby K; Morosoli JJ; Tong X; Marrington S; Middeldorp C; Scott JG; Vinkhuyzen A; Shabalin AA; Corley R; Evans LM; Sugden K; Alemany S; Sass L; Vinding R; Ruth K; Tyrrell J; Davies GE; Ehli EA; Hagenbeek FA; De Zeeuw E; Van Beijsterveldt TCEM; Larsson H; Snieder H; Verhulst FC; Amin N; Whipp AM; Korhonen T; Vuoksimaa E; Rose RJ; Uitterlinden AG; Heath AC; Madden P; Haavik J; Harris JR; Helgeland Ø; Johansson S; Knudsen GPS; Njolstad PR; Lu Q; Rodriguez A; Henders AK; Mamun A; Najman JM; Brown S; Hopfer C; Krauter K; Reynolds C; Smolen A; Stallings M; Wadsworth S; Wall TL; Silberg JL; Miller A; Keltikangas-Järvinen L; Hakulinen C; Pulkki-Råback L; Havdahl A; Magnus P; Raitakari OT; Perry JRB; Llop S; Lopez-Espinosa M-J; Bønnelykke K; Bisgaard H; Sunyer J; Lehtimäki T; Arseneault L; Standl M; Heinrich J; Boden J; Pearson J; Horwood LJ; Kennedy M; Poulton R; Eaves LJ; Maes HH; Hewitt J; Copeland WE; Costello EJ; Williams GM; Wray N; Järvelin M-R; McGue M; Iacono W; Caspi A; Moffitt TE; Whitehouse A; Pennell CE; Klump KL; Burt SA; Dick DM; Reichborn-Kjennerud T; Martin NG; Medland SE; Vrijkotte T; Kaprio J; Tiemeier H; Davey Smith G; Hartman CA; Oldehinkel AJ; Casas M; Ribasés M; Lichtenstein P; Lundström S; Plomin R; Bartels M; Nivard MG; Boomsma DI
  • Article: MOLECULAR PSYCHIATRY. 2021;26(6):2429-2439
    Clements CC; Karlsson R; Lu Y; Juréus A; Rück C; Andersson E; Boberg J; Pedersen NL; Bulik CM; Nordenskjöld A; Pålsson E; Sullivan PF; Landén M
  • Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):163
    Kowalec K; Lu Y; Song J; Dalman C; Hultman CM; Larsson H; Lichtenstein P; Sullivan PF
  • Article: NATURE COMMUNICATIONS. 2020;11(1):4637
    Lu D; Song J; Lu Y; Fall K; Chen X; Fang F; Landén M; Hultman CM; Czene K; Sullivan P; Tamimi RM; Valdimarsdóttir UA
  • Article: MOLECULAR PSYCHIATRY. 2020;25(8):1809-1821
    Brikell I; Larsson H; Lu Y; Pettersson E; Chen Q; Kuja-Halkola R; Karlsson R; Lahey BB; Lichtenstein P; Martin J
  • Article: PLOS GENETICS. 2020;16(6):e1008725
    Ferreira MAR; Vonk JM; Baurecht H; Marenholz I; Tian C; Hoffman JD; Helmer Q; Tillander A; Ullemar V; Lu Y; Grosche S; Rüschendorf F; Granell R; Brumpton BM; Fritsche LG; Bhatta L; Gabrielsen ME; Nielsen JB; Zhou W; Hveem K; Langhammer A; Holmen OL; Løset M; Abecasis GR; Willer CJ; Emami NC; Cavazos TB; Witte JS; Szwajda A; 23andMe Research Team; collaborators of the SHARE study; Hinds DA; Hübner N; Weidinger S; Magnusson PK; Jorgenson E; Karlsson R; Paternoster L; Boomsma DI; Almqvist C; Lee Y-A; Koppelman GH
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    Earp MA; Kelemen LE; Magliocco AM; Swenerton KD; Chenevix-Trench G; Australian Cancer Study; Australian Ovarian Cancer Study Group; Lu Y; Hein A; Ekici AB; Beckmann MW; Fasching PA; Lambrechts D; Despierre E; Vergote I; Lambrechts S; Doherty JA; Rossing MA; Chang-Claude J; Rudolph A; Friel G; Moysich KB; Odunsi K; Sucheston-Campbell L; Lurie G; Goodman MT; Carney ME; Thompson PJ; Runnebaum IB; Dürst M; Hillemanns P; Dörk T; Antonenkova N; Bogdanova N; Leminen A; Nevanlinna H; Pelttari LM; Butzow R; Bunker CH; Modugno F; Edwards RP; Ness RB; du Bois A; Heitz F; Schwaab I; Harter P; Karlan BY; Walsh C; Lester J; Jensen A; Kjær SK; Høgdall CK; Høgdall E; Lundvall L; Sellers TA; Fridley BL; Goode EL; Cunningham JM; Vierkant RA; Giles GG; Baglietto L; Severi G; Southey MC; Liang D; Wu X; Lu K; Hildebrandt MAT; Levine DA; Bisogna M; Schildkraut JM; Iversen ES; Weber RP; Berchuck A; Cramer DW; Terry KL; Poole EM; Tworoger SS; Bandera EV; Chandran U; Orlow I; Olson SH; Wik E; Salvesen HB; Bjorge L; Halle MK; van Altena AM; Aben KKH; Kiemeney LA; Massuger LFAG; Pejovic T; Bean YT; Cybulski C; Gronwald J; Lubinski J; Wentzensen N; Brinton LA; Lissowska J; Garcia-Closas M; Dicks E; Dennis J; Easton DF; Song H; Tyrer JP; Pharoah PDP; Eccles D; Campbell IG; Whittemore AS; McGuire V; Sieh W; Rothstein JH; Flanagan JM; Paul J; Brown R; Phelan CM; Risch HA; McLaughlin JR; Narod SA; Ziogas A; Anton-Culver H; Gentry-Maharaj A; Menon U; Gayther SA; Ramus SJ; Wu AH; Pearce CL; Pike MC; Dansonka-Mieszkowska A; Rzepecka IK; Szafron LM; Kupryjanczyk J; Cook LS; Le ND; Brooks-Wilson A; Ovarian Cancer Association Consortium
  • Article: GYNECOLOGIC ONCOLOGY. 2013;131(1):8-14
    Johnatty SE; Beesley J; Gao B; Chen X; Lu Y; Law MH; Henderson MJ; Russell AJ; Hedditch EL; Emmanuel C; Fereday S; Webb PM; Australian Ovarian Cancer Study Group; Goode EL; Vierkant RA; Fridley BL; Cunningham JM; Fasching PA; Beckmann MW; Ekici AB; Hogdall E; Kjaer SK; Jensen A; Hogdall C; Brown R; Paul J; Lambrechts S; Despierre E; Vergote I; Lester J; Karlan BY; Heitz F; du Bois A; Harter P; Schwaab I; Bean Y; Pejovic T; Levine DA; Goodman MT; Camey ME; Thompson PJ; Lurie G; Shildkraut J; Berchuck A; Terry KL; Cramer DW; Norris MD; Haber M; MacGregor S; deFazio A; Chenevix-Trench G
  • Article: NATURE GENETICS. 2013;45(4):371-384
    Bojesen SE; Pooley KA; Johnatty SE; Beesley J; Michailidou K; Tyrer JP; Edwards SL; Pickett HA; Shen HC; Smart CE; Hillman KM; Mai PL; Lawrenson K; Stutz MD; Lu Y; Karevan R; Woods N; Johnston RL; French JD; Chen X; Weischer M; Nielsen SF; Maranian MJ; Ghoussaini M; Ahmed S; Baynes C; Bolla MK; Wang Q; Dennis J; McGuffog L; Barrowdale D; Lee A; Healey S; Lush M; Tessier DC; Vincent D; Bacot F; Australian Cancer Study; Australian Ovarian Cancer Study; Kathleen Cuningham Foundation Consortium for Resea; Gene Environment Interaction and Breast Cancer (GE; Swedish Breast Cancer Study (SWE-BRCA); Hereditary Breast and Ovarian Cancer Research Grou; Epidemiological study of BRCA1 & BRCA2 Mutation Ca; Genetic Modifiers of Cancer Risk in BRCA1/2 Mutati; Vergote I; Lambrechts S; Despierre E; Risch HA; González-Neira A; Rossing MA; Pita G; Doherty JA; Alvarez N; Larson MC; Fridley BL; Schoof N; Chang-Claude J; Cicek MS; Peto J; Kalli KR; Broeks A; Armasu SM; Schmidt MK; Braaf LM; Winterhoff B; 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Weber RP; Flesch-Janys D; Iversen E; Nickels S; Schildkraut JM; Silva IDS; Cramer DW; Gibson L; Terry KL; Fletcher O; Vitonis AF; van der Schoot CE; Poole EM; Hogervorst FBL; Tworoger SS; Liu J; Bandera EV; Li J; Olson SH; Humphreys K; Orlow I; Blomqvist C; Rodriguez-Rodriguez L; Aittomäki K; Salvesen HB; Muranen TA; Wik E; Brouwers B; Krakstad C; Wauters E; Halle MK; Wildiers H; Kiemeney LA; Mulot C; Aben KK; Laurent-Puig P; Altena AM; Truong T; Massuger LFAG; Benitez J; Pejovic T; Perez JIA; Hoatlin M; Zamora MP; Cook LS; Balasubramanian SP; Kelemen LE; Schneeweiss A; Le ND; Sohn C; Brooks-Wilson A; Tomlinson I; Kerin MJ; Miller N; Cybulski C; Henderson BE; Menkiszak J; Schumacher F; Wentzensen N; Le Marchand L; Yang HP; Mulligan AM; Glendon G; Engelholm SA; Knight JA; Høgdall CK; Apicella C; Gore M; Tsimiklis H; Song H; Southey MC; Jager A; den Ouweland AMW; Brown R; Martens JWM; Flanagan JM; Kriege M; Paul J; Margolin S; Siddiqui N; Severi G; Whittemore AS; Baglietto L; McGuire V; 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Tea M-K; Paluch SS; Laitman Y; Skytte A-B; Kruse TA; Jensen UB; Robson M; Gerdes A-M; Ejlertsen B; Foretova L; Savage SA; Lester J; Soucy P; Kuchenbaecker KB; Olswold C; Cunningham JM; Slager S; Pankratz VS; Dicks E; Lakhani SR; Couch FJ; Hall P; Monteiro ANA; Gayther SA; Pharoah PDP; Reddel RR; Goode EL; Greene MH; Easton DF; Berchuck A; Antoniou AC; Chenevix-Trench G; Dunning AM
  • Article: NATURE GENETICS. 2013;45(2):155-163
    Lu Y; Vitart V; Burdon KP; Khor CC; Bykhovskaya Y; Mirshahi A; Hewitt AW; Koehn D; Hysi PG; Ramdas WD; Zeller T; Vithana EN; Cornes BK; Tay W-T; Tai ES; Cheng C-Y; Liu J; Foo J-N; Saw SM; Thorleifsson G; Stefansson K; Dimasi DP; Mills RA; Mountain J; Ang W; Hoehn R; Verhoeven VJM; Grus F; Wolfs R; Castagne R; Lackner KJ; Springelkamp H; Yang J; Jonasson F; Leung DYL; Chen LJ; Tham CCY; Rudan I; Vatavuk Z; Hayward C; Gibson J; Cree AJ; MacLeod A; Ennis S; Polasek O; Campbell H; Wilson JF; Viswanathan AC; Fleck B; Li X; Siscovick D; Taylor KD; Rotter JI; Yazar S; Ulmer M; Li J; Yaspan BL; Ozel AB; Richards JE; Moroi SE; Haines JL; Kang JH; Pasquale LR; Allingham RR; Ashley-Koch A; NEIGHBOR Consortium; Mitchell P; Wang JJ; Wright AF; Pennell C; Spector TD; Young TL; Klaver CCW; Martin NG; Montgomery GW; Anderson MG; Aung T; Willoughby CE; Wiggs JL; Pang CP; Thorsteinsdottir U; Lotery AJ; Hammond CJ; van Duijn CM; Hauser MA; Rabinowitz YS; Pfeiffer N; Mackey DA; Craig JE; Macgregor S; Wong TY
  • Article: TWIN RESEARCH AND HUMAN GENETICS. 2012;15(5):615-623
    Lu Y; Chen X; Beesley J; Johnatty SE; deFazio A; AOCS Study group; Lambrechts S; Lambrechts D; Despierre E; Vergotes I; Chang-Claude J; Hein R; Nickels S; Wang-Gohrke S; Dörk T; Dürst M; Antonenkova N; Bogdanova N; Goodman MT; Lurie G; Wilkens LR; Carney ME; Butzow R; Nevanlinna H; Heikkinen T; Leminen A; Kiemeney LA; Massuger LFAG; van Altena AM; Aben KK; Kjaer SK; Høgdall E; Jensen A; Brooks-Wilson A; Le N; Cook L; Earp M; Kelemen L; Easton D; Pharoah P; Song H; Tyrer J; Ramus S; Menon U; Gentry-Maharaj A; Gayther SA; Bandera EV; Olson SH; Orlow I; Rodriguez-Rodriguez L; Macgregor S; Chenevix-Trench G
  • Article: HUMAN GENETICS. 2012;131(9):1467-1480
    Verhoeven VJM; Hysi PG; Saw S-M; Vitart V; Mirshahi A; Guggenheim JA; Cotch MF; Yamashiro K; Baird PN; Mackey DA; Wojciechowski R; Ikram MK; Hewitt AW; Duggal P; Janmahasatian S; Khor C-C; Fan Q; Zhou X; Young TL; Tai E-S; Goh L-K; Li Y-J; Aung T; Vithana E; Teo Y-Y; Tay W; Sim X; Rudan I; Hayward C; Wright AF; Polasek O; Campbell H; Wilson JF; Fleck BW; Nakata I; Yoshimura N; Yamada R; Matsuda F; Ohno-Matsui K; Nag A; McMahon G; St Pourcain B; Lu Y; Rahi JS; Cumberland PM; Bhattacharya S; Simpson CL; Atwood LD; Li X; Raffel LJ; Murgia F; Portas L; Despriet DDG; van Koolwijk LME; Wolfram C; Lackner KJ; Tönjes A; Mägi R; Lehtimäki T; Kähönen M; Esko T; Metspalu A; Rantanen T; Pärssinen O; Klein BE; Meitinger T; Spector TD; Oostra BA; Smith AV; de Jong PTVM; Hofman A; Amin N; Karssen LC; Rivadeneira F; Vingerling JR; Eiríksdóttir G; Gudnason V; Döring A; Bettecken T; Uitterlinden AG; Williams C; Zeller T; Castagné R; Oexle K; van Duijn CM; Iyengar SK; Mitchell P; Wang JJ; Höhn R; Pfeiffer N; Bailey-Wilson JE; Stambolian D; Wong T-Y; Hammond CJ; Klaver CCW
  • Article: CLINICAL CANCER RESEARCH. 2011;17(16):5490-5500
    Huang RS; Johnatty SE; Gamazon ER; Im HK; Ziliak D; Duan S; Zhang W; Kistner EO; Chen P; Beesley J; Mi S; O'Donnell PH; Fraiman YS; Das S; Cox NJ; Lu Y; Macgregor S; Goode EL; Vierkant RA; Fridley BL; Hogdall E; Kjaer SK; Jensen A; Moysich KB; Grasela M; Odunsi K; Brown R; Paul J; Lambrechts D; Despierre E; Vergote I; Gross J; Karlan BY; Defazio A; Chenevix-Trench G; Australian Ovarian Cancer Study Group; Dolan ME
  • Article: CLINICAL CANCER RESEARCH. 2011;17(11):3742-3750
    Pharoah PDP; Palmieri RT; Ramus SJ; Gayther SA; Andrulis IL; Anton-Culver H; Antonenkova N; Antoniou AC; Goldgar D; BCFR Investigators; Beattie MS; Beckmann MW; Birrer MJ; Bogdanova N; Bolton KL; Brewster W; Brooks-Wilson A; Brown R; Butzow R; Caldes T; Caligo MA; Campbell I; Chang-Claude J; Chen YA; Cook LS; Couch FJ; Cramer DW; Cunningham JM; Despierre E; Doherty JA; Dörk T; Dürst M; Eccles DM; Ekici AB; Easton D; EMBRACE Investigators; Fasching PA; de Fazio A; Fenstermacher DA; Flanagan JM; Fridley BL; Friedman E; Gao B; Sinilnikova O; GEMO Study Collaborators; Gentry-Maharaj A; Godwin AK; Goode EL; Goodman MT; Gross J; Hansen TVO; Harnett P; Rookus M; HEBON Investigators; Heikkinen T; Hein R; Høgdall C; Høgdall E; Iversen ES; Jakubowska A; Johnatty SE; Karlan BY; Kauff ND; Kaye SB; Chenevix-Trench G; kConFab Investigators and the Consortium of Invest; Kelemen LE; Kiemeney LA; Kjaer SK; Lambrechts D; Lapolla JP; Lázaro C; Le ND; Leminen A; Leunen K; Levine DA; Lu Y; Lundvall L; Macgregor S; Marees T; Massuger LF; McLaughlin JR; Menon U; Montagna M; Moysich KB; Narod SA; Nathanson KL; Nedergaard L; Ness RB; Nevanlinna H; Nickels S; Osorio A; Paul J; Pearce CL; Phelan CM; Pike MC; Radice P; Rossing MA; Schildkraut JM; Sellers TA; Singer CF; Song H; Stram DO; Sutphen R; Lindblom A; SWE-BRCA Investigators; Terry KL; Tsai Y-Y; van Altena AM; Vergote I; Vierkant RA; Vitonis AF; Walsh C; Wang-Gohrke S; Wappenschmidt B; Wu AH; Ziogas A; Berchuck A; Risch HA; Ovarian Cancer Association Consortium
  • Article: PLOS ONE. 2011;6(9):e24987
    Beesley J; Pickett HA; Johnatty SE; Dunning AM; Chen X; Li J; Michailidou K; Lu Y; Rider DN; Palmieri RT; Stutz MD; Lambrechts D; Despierre E; Lambrechts S; Vergote I; Chang-Claude J; Nickels S; Vrieling A; Flesch-Janys D; Wang-Gohrke S; Eilber U; Bogdanova N; Antonenkova N; Runnebaum IB; Dörk T; Goodman MT; Lurie G; Wilkens LR; Matsuno RK; Kiemeney LA; Aben KKH; Marees T; Massuger LFAG; Fridley BL; Vierkant RA; Bandera EV; Olson SH; Orlow I; Rodriguez-Rodriguez L; Cook LS; Le ND; Brooks-Wilson A; Kelemen LE; Campbell I; Gayther SA; Ramus SJ; Gentry-Maharaj A; Menon U; Ahmed S; Baynes C; Pharoah PD; kConFab Investigators; Australian Ovarian Cancer Study Group; ABCTB Investigators; Muir K; Lophatananon A; Chaiwerawattana A; Wiangnon S; Macgregor S; Easton DF; Reddel RR; Goode EL; Chenevix-Trench G; Ovarian Cancer Association Consortium
  • Article: PLOS GENETICS. 2010;6(5):e1000947
    Lu Y; Dimasi DP; Hysi PG; Hewitt AW; Burdon KP; Toh T; Ruddle JB; Li YJ; Mitchell P; Healey PR; Montgomery GW; Hansell N; Spector TD; Martin NG; Young TL; Hammond CJ; Macgregor S; Craig JE; Mackey DA
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