Ana Teixeira

About me
Publications
CV
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About me

Ana Teixeira was born in 1974 in Vila Verde, Portugal, and in 1997 graduated from the Technical University of Lisbon (now University of Lisbon) with a degree in Chemical Engineering. She did doctoral studies at the University of Wisconsin-Madison, USA, and her dissertation on bionanotechnology was presented in 2003.

After performing postdoc work at Karolinska Institutet in 2003-2008, Teixeira has been leading a research team at KI since 2008. In 2018 she became Docent in Nanomedicine at the Department of Medical Biochemistry and Biophysics.

Research

The Teixeira Lab uses a multi-disciplinary approach including materials science, biophysics and cell biology to understand how cells interact with their microenvironment.

Selected publications

Article: NATURE NANOTECHNOLOGY. 2024;19(2):237-245
Multivalent insulin receptor activation using insulin-DNA origami nanostructures
Spratt J; Dias JM; Kolonelou C; Kiriako G; Engstrom E; Petrova E; Karampelias C; Cervenka I; Papanicolaou N; Lentini A; Reinius B; Andersson O; Ambrosetti E; Ruas JL; Teixeira AI
Article: ACS NANO. 2021;15(2):3441-3452
Spatial Regulation of T-Cell Signaling by Programmed Death-Ligand 1 on Wireframe DNA Origami Flat Sheets
Fang T; Alvelid J; Spratt J; Ambrosetti E; Testa I; Teixeira AI
Article: NATURE NANOTECHNOLOGY. 2021;16(1):85-95
A DNA-nanoassembly-based approach to map membrane protein nanoenvironments.
Ambrosetti E; Bernardinelli G; Hoffecker I; Hartmanis L; Kiriako G; de Marco A; Sandberg R; Högberg B; Teixeira AI
Article: NUCLEIC ACIDS RESEARCH (NAR). 2020;48(10):5777-5787
Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers
Verheyen T; Fang T; Lindenhofer D; Wang Y; Akopyan K; Lindqvist A; Hogberg B; Teixeira AI
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(6):2978-2986
Modeling the transport of nuclear proteins along single skeletal muscle cells
Taylor-Weiner H; Grigsby CL; Ferreira DMS; Dias JM; Stevens MM; Ruas JL; Teixeira AI
Article: MOLECULAR METABOLISM. 2018;7:12-22
Neurturin is a PGC-1 α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation
Mills R; Taylor-Weiner H; Correia JC; Agudelo LZ; Allodi I; Kolonelou C; Martinez-Redondo V; Ferreira DMS; Nichterwitz S; Comley LH; Lundin V; Hedlund E; Ruas JL; Teixeira AI
Article: CELL REPORTS. 2014;8(3):665-670
CtBPs Sense Microenvironmental Oxygen Levels to Regulate Neural Stem Cell State
Dias JM; Ilkhanizadeh S; Karaca E; Duckworth JK; Lundin V; Rosenfeld MG; Ericson J; Hermanson O; Teixeira AI
Article: NATURE METHODS. 2014;11(8):841-846
Spatial control of membrane receptor function using ligand nanocalipers
Shaw A; Lundin V; Petrova E; Fordos F; Benson E; Al-Amin A; Herland A; Blokzijl A; Hogberg B; Teixeira AI

Articles

Article: MOLECULAR METABOLISM. 2024;82:101912
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition
Ducommun S; Jannig PR; Cervenka I; Murgia M; Mittenbuhler MJ; Chernogubova E; Dias JM; Jude B; Correia JC; Van Vranken JG; Ocana-Santero G; Porsmyr-Palmertz M; Haworth SM; Martinez-Redondo V; Liu Z; Carlstrom M; Mann M; Lanner JT; Teixeira AI; Maegdefessel L; Spiegelman BM; Ruas JL
Article: NATURE COMMUNICATIONS. 2024;15(1):465
Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force
Smyrlaki I; Foerdos F; Rocamonde-Lago I; Wang Y; Shen B; Lentini A; Luca VC; Reinius B; Teixeira AI; Hoegberg B
Article: JOURNAL OF MOLECULAR BIOLOGY. 2023;435(20):168262
Affinity Maturated Transferrin Receptor Apical Domain Blocks Machupo Virus Glycoprotein Binding
Sjostrom DJ; Grill B; Ambrosetti E; Veetil AA; Mohlin C; Teixeira AI; Oberdofer G; Bjelic S
Article: ACS APPLIED BIO MATERIALS. 2023;6(9):3790-3797
Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
Ilkhanizadeh S; Gracias A; Aslund AKO; Back M; Simon R; Kavanagh E; Migliori B; Neofytou C; Nelander S; Westermark B; Uhrbom L; Forsberg-Nilsson K; Konradsson P; Teixeira AI; Uhlen P; Joseph B; Hermanson O; Nilsson KPR
Article: SCIENCE ADVANCES. 2022;8(41):eabm1847
Cellular shape reinforces niche to stem cell signaling in the small intestine
Pentinmikko N; Lozano R; Scharaw S; Andersson S; Englund JI; Castillo-Azofeifa D; Gallagher A; Broberg M; Song K-Y; Carvajal AS; Speidel AT; Sundstrom M; Allbritton N; Stevens MM; Klein OD; Teixeira A; Katajisto P
Article: ACS APPLIED BIO MATERIALS. 2022;5(7):3310-3319
Patterned Carboxymethyl-Dextran Functionalized Surfaces Using Organic Mixed Monolayers for Biosensing Applications
Ambrosetti E; Conti M; Teixeira AI; Dal Zilio S
Article: THE FEBS JOURNAL. 2022;289(10):2935-2947
Motif-driven protein binder design towards transferrin receptor helical domain
Sjostrom DJ; Mohlin C; Ambrosetti E; Garforth SJ; Teixeira AI; Bjelic S
Article: ADVANCED MATERIALS. 2021;33(29):e2008457
DNA Origami Penetration in Cell Spheroid Tissue Models is Enhanced by Wireframe Design
Wang Y; Benson E; Fordos F; Lolaico M; Baars I; Fang T; Teixeira AI; Hogberg B
Article: BIOTECHNOLOGY AND BIOENGINEERING. 2021;118(6):2234-2242
Effects of topological constraints on the alignment and maturation of multinucleated myotubes
Song K-Y; Correia JC; Ruas JL; Teixeira AI
Article: SMALL. 2019;15(1):e1803628
Solution-Controlled Conformational Switching of an Anchored Wireframe DNA Nanostructure
Hoffecker IT; Chen S; Gadin A; Bosco A; Teixeira AI; Hogberg B
Article: MICROFLUIDICS AND NANOFLUIDICS. 2018;22(11):135
Enhancement of the surface free energy of PDMS for reversible and leakage-free bonding of PDMS-PS microfluidic cell-culture systems
Song K-Y; Zhang H; Zhang W-J; Teixeira A
Article: ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2016;55(31):8869-8872
Computer-Aided Production of Scaffolded DNA Nanostructures from Flat Sheet Meshes
Benson E; Mohammed A; Bosco A; Teixeira AI; Orponen P; Hogberg B
Article: STEM CELL REPORTS. 2014;3(3):502-515
Neural Stem Cell Differentiation Is Dictated by Distinct Actions of Nuclear Receptor Corepressors and Histone Deacetylases
Castelo-Branco GG; Lilja T; Wallenborg K; Falcao AM; Marques SC; Gracias A; Solum D; Paap R; Walfridsson J; Teixeira AI; Rosenfeld MG; Jepsen K; Hermanson O
Article: BIOMATERIALS. 2014;35(6):1907-1913
Preservation of aortic root architecture and properties using a detergent-enzymatic perfusion protocol
Friedrich LH; Jungebluth P; Sjoqvist S; Lundin V; Haag JC; Lemon G; Gustafsson Y; Ajalloueian F; Sotnichenko A; Kielstein H; Burguillos MA; Joseph B; Teixeira AI; Lim ML; Macchiarini P
Article: BIOMATERIALS. 2014;35(5):1420-1428
A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons
Zhang D; Pekkanen-Mattila M; Shahsavani MO; Falk A; Teixeira AI; Herland A
Article: PLOS ONE. 2013;8(8):e72409
Erg Channel Is Critical in Controlling Cell Volume during Cell Cycle in Embryonic Stem Cells
Abdelhady S; Kitambi SS; Lundin V; Aufschnaiter R; Sekyrova P; Sinha I; Lundgren KT; Castelo-Branco G; Linnarsson S; Wedlich-Soeldner R; Teixeira A; Andang M
Article: BIOMATERIALS. 2012;33(17):4319-4326
The concept of in vivo airway tissue engineering
Jungebluth P; Bader A; Baiguera S; Moller S; Jaus M; Lim ML; Fried K; Kjartansdottir KR; Go T; Nave H; Harringer W; Lundin V; Teixeira AI; Macchiarini P
Article: ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2011;50(52):12529-12533
Electrochemical Control of Growth Factor Presentation To Steer Neural Stem Cell Differentiation
Herland A; Persson KM; Lundin V; Fahlman M; Berggren M; Jager EWH; Teixeira AI
Article: PLOS ONE. 2011;6(4):e18624
Control of Neural Stem Cell Survival by Electroactive Polymer Substrates
Lundin V; Herland A; Berggren M; Jager EWH; Teixeira AI
Article: MRS BULLETIN. 2010;35(8):591-596
Designing and Engineering Stem Cell Niches
Teixeira AI; Hermanson O; Werner C
Article: CELL DEATH AND DIFFERENTIATION. 2009;16(9):1256-1265
p57Kip2 is a repressor of Mash1 activity and neuronal differentiation in neural stem cells
Joseph B; Andersson ER; Vlachos P; Sodersten E; Liu L; Teixeira AI; Hermanson O
Article: BIOMATERIALS. 2009;30(27):4567-4572
The promotion of neuronal maturation on soft substrates
Teixeira AI; Ilkhanizadeh S; Wigenius JA; Duckworth JK; Inganas O; Hermanson O
Article: BIOMATERIALS. 2007;28(27):3936-3943
Inkjet printing of macromolecules on hydrogels to steer neural stem cell differentiation
Ilkhanizadeh S; Teixeira AI; Hermanson O
Article: BIOMATERIALS. 2006;27(21):3945-3954
The effect of environmental factors on the response of human corneal epithelial cells to nanoscale substrate topography.
Teixeira AI; McKie GA; Foley JD; Bertics PJ; Nealey PF; Murphy CJ
Article: DEVELOPMENTAL NEUROSCIENCE. 2006;28(1-2):118-127
Recording Notch signaling in real time
Hansson EM; Teixeira AI; Gustafsson MV; Dohda T; Chapman G; Meletis K; Muhr J; Lendahl U
Article: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH - PART A. 2004;71(3):369-376
Responses of human keratocytes to micro- and nanostructured substrates.
Teixeira AI; Nealey PF; Murphy CJ
Article: JOURNAL OF CELL SCIENCE. 2004;117(Pt 15):3153-3164
Biological length scale topography enhances cell-substratum adhesion of human corneal epithelial cells.
Karuri NW; Liliensiek S; Teixeira AI; Abrams G; Campbell S; Nealey PF; Murphy CJ
Article: JOURNAL OF CELL SCIENCE. 2003;116(Pt 10):1881-1892
Epithelial contact guidance on well-defined micro- and nanostructured substrates.
Teixeira AI; Abrams GA; Bertics PJ; Murphy CJ; Nealey PF
Article: ADVANCED MATERIALS. 2002;14(20):1468-1472
Fabrication of polymeric substrates with well-defined nanometer-scale topography and tailored surface chemistry
Kim SR; Teixeira AI; Nealey PF; Wendt AE; Abbott NL
Article: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH - PART B APPLIED BIOMATERIALS. 2000;52(2):261-269
Adhesion and proliferation of corneal epithelial cells on self-assembled monolayers.
Franco M; Nealey PF; Campbell S; Teixeira AI; Murphy CJ
Article: BIOCATALYSIS AND BIOTRANSFORMATION. 1998;16(2):145-162
Lipase mediated resolution of γ-branched chain fatty acid methyl esters
Heinsman NWJT; Orrenius SC; Marcelis CLM; Teixeira AD; Franssen MCR; van der Padt A; Jongejan JA; de Groot A
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All other publications

Preprint: BIORXIV. 2023
Biodistribution of DNA-origami nanostructures in live zebrafish embryos with single-cell resolution
Kolonelou C; Bräutigam L; Edwards S; Engström E; Dias J; Spratt J; Karampelias C; Wennmalm S; Brismar H; Andersson O; Teixeira A
Review: CELL RESEARCH. 2007;17(1):56-61
Getting the right stuff:: controlling neural stem cell state and fate in vivo and in vitro with biomaterials
Teixeira AI; Duckworth JK; Hermanson O
Published conference paper: JOURNAL OF VACUUM SCIENCE AND TECHNOLOGY B. 2003;21(2):683-687
Cell behavior on lithographically defined nanostructured substrates
Teixeira AI; Abrams GA; Murphy CJ; Nealey PF

Employments

Principal Researcher, Department of Physiology and Pharmacology, Karolinska Institutet, 2023-

Degrees and Education

Docent, Karolinska Institutet, 2018

About me

Research

Selected publications

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI