Lars Klareskog

About me
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CV
Public outreach and news

About me

Senior Professor of Rheumatology.

Articles

Article: RHEUMATOLOGY. 2024;63(11):3106-3114
Identification of circulating autoantibodies to non-modified proteins associated with ACPA status in early rheumatoid arthritis
Lourido L; Joshua V; Hansson M; Sjoberg R; Pin E; Ruiz-Romero C; Nilsson P; Alfredsson L; Klareskog L; Blanco FJ
Article: RHEUMATOLOGY. 2024;63(5):1221-1229
Genome-wide investigation of persistence with methotrexate treatment in early rheumatoid arthritis
Sysojev AO; Saevarsdottir S; Diaz-Gallo L-M; Silberberg GN; Alfredsson L; Klareskog L; Baecklund E; Bjorkman L; Kastbom A; Rantapaa-Dahlqvist S; Turesson C; Jonsdottir I; Stefansson K; Frisell T; Padyukov L; Askling J; Westerlind H
Article: MICROBIOLOGY SPECTRUM. 2024;12(4):e0298123-e02923
The serological immunogenicity of the third and fourth doses of COVID-19 vaccine in patients with inflammatory rheumatic diseases on different biologic or targeted DMARDs: a Swedish nationwide study (COVID-19-REUMA)
Frodlund M; Nived P; Chatzidionysiou K; Soedergren A; Klingberg E; Hansson M; Ohlsson S; Pin E; Bengtsson A; Klareskog L; Kapetanovic M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2024;83(3):277-287
In early rheumatoid arthritis, anticitrullinated peptide antibodies associate with low number of affected joints and rheumatoid factor associates with systemic inflammation
Pertsinidou E; Saevarsdottir S; Manivel VA; Klareskog L; Alfredsson L; Mathsson-Alm L; Hansson M; Cornillet M; Serre G; Holmdahl R; Skriner K; Jakobsson P-J; Westerlind H; Askling J; Roennelid J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(3):e2315354120
Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents Infection of Omicron lineages
Marcotte H; Cao Y; Zuo F; Simonelli L; Sammartino JC; Pedotti M; Sun R; Cassaniti I; Hagbom M; Piralla A; Yang J; Du L; Percivalle E; Bertoglio F; Schubert M; Abolhassani H; Sherina N; Guerra C; Borte S; Rezaei N; Kumagai-Braesch M; Xue Y; Su C; Yan Q; He P; Groenwall C; Klareskog L; Calzolai L; Cavalli A; Wang Q; Robbiani DF; Hust M; Shi Z; Feng L; Svensson L; Chen L; Bao L; Baldanti F; Xiao J; Qin C; Hammarstrom L; Yang X; Varani L; Xie XS; Pan-Hammarstrom Q
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(11):1910-1922
Rheumatoid Arthritis-Specific Autoimmunity in the Lung Before and at the Onset of Disease
Joshua V; Loberg Haarhaus M; Hensvold A; Wahamaa H; Gerstner C; Hansson M; Israelsson L; Stalesen R; Skoeld M; Grunewald J; Klareskog L; Groenwall C; Rethi B; Catrina A; Malmstrom V
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(11):105320
Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients
Sahlstrom P; Joshua V; Valkovskaia V; Biese C; Stalesen R; Israelsson L; Vegvari A; Scheel-Toellner D; Klareskog L; Hansson M; Hensvold A; Malmstrom V; Gronwall C
Article: RHEUMATOLOGY. 2023;62(10):3280-3290
Using human genetics to understand the epidemiological association between obesity, serum urate, and gout
Zhang L; Zhang W; Xiao C; Wu X; Cui H; Yan P; Yang C; Tang M; Wang Y; Chen L; Liu Y; Zou Y; Alfredsson L; Klareskog L; Yang Y; Yao Y; Li J; Liu Z; Yang C; Jiang X; Zhang B
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2023;113:212-227
Insights into FcγR involvement in pain-like behavior induced by an RA-derived anti-modified protein autoantibody
Jurczak A; Sandor K; Farinotti AB; Krock E; Hunt MA; Agalave NM; Barbier J; Simon N; Wang Z; Rudjito R; Vazquez-Mora JA; Martinez-Martinez A; Raoof R; Eijkelkamp N; Gronwall C; Klareskog L; Jimenez-Andrade JM; Marchand F; Svensson CI
Article: NATURE IMMUNOLOGY. 2023;24(9):1540-1551
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets
Zhao JH; Stacey D; Eriksson N; Macdonald-Dunlop E; Hedman AK; Kalnapenkis A; Enroth S; Cozzetto D; Digby-Bell J; Marten J; Folkersen L; Herder C; Jonsson L; Bergen SE; Gieger C; Needham EJ; Surendran P; Metspalu A; Milani L; Magi R; Nelis M; Hudjasov G; Paul DS; Polasek O; Thorand B; Grallert H; Roden M; Vosa U; Esko T; Hayward C; Johansson A; Gyllensten U; Powell N; Hansson O; Mattsson-Carlgren N; Joshi PK; Danesh J; Padyukov L; Klareskog L; Landen M; Wilson JF; Siegbahn A; Wallentin L; Malarstig A; Butterworth AS; Peters JE
Article: HUMAN GENOMICS. 2023;17(1):81
A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis
Jiang Y; Liu Q; Alfredsson L; Klareskog L; Kockum I; Jiang X
Article: SCIENTIFIC REPORTS. 2023;13(1):10058
Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs
Hedman AK; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr SS; Jelinsky SA
Article: NATURE COMMUNICATIONS. 2023;14(1):3453
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Oddsson A; Sulem P; Sveinbjornsson G; Arnadottir GM; Steinthorsdottir V; Halldorsson G; Atlason BO; Oskarsson G; Helgason H; Nielsen HS; Westergaard DA; Karjalainen J; Katrinardottir H; Fridriksdottir RB; Jensson B; Tragante VA; Ferkingstad E; Jonsson H; Gudjonsson S; Beyter D; Moore KHS; Thordardottir H; Kristmundsdottir S; Stefansson O; Rantapaa-Dahlqvist S; Sonderby IE; Didriksen MA; Stridh P; Haavik J; Tryggvadottir L; Frei O; Walters GB; Kockum I; Hjalgrim H; Olafsdottir T; Selbaek G; Nyegaard M; Erikstrup C; Brodersen T; Saevarsdottir S; Olsson T; Nielsen KR; Haraldsson A; Bruun MT; Hansen TF; Steingrimsdottir T; Jacobsen RLT; Lie R; Djurovic S; Alfredsson L; Lopez de Lapuente Portilla A; Brunak S; Melsted PV; Halldorsson B; Saemundsdottir J; Magnusson OT; Padyukov L; Banasik K; Rafnar T; Askling J; Klareskog L; Pedersen OB; Masson G; Havdahl A; Nilsson BA; Andreassen O; Daly M; Ostrowski SR; Jonsdottir I; Stefansson H; Holm H; Helgason A; Thorsteinsdottir U; Stefansson KF; Gudbjartsson D
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(6):872-878
Disease Activity and Health-Related Quality of Life Among Patients With Rheumatoid Arthritis With Different Alcohol Consumption Habits
Alfredsson L; Klareskog L; Hedstrom AK
Article: VACCINE. 2023;41(20):3247-3257
The impact of immunomodulating treatment on the immunogenicity of COVID-19 vaccines in patients with immune-mediated inflammatory rheumatic diseases compared to healthy controls. A Swedish nationwide study (COVID19-REUMA)
Frodlund M; Nived P; Chatzidionysiou A; Sodergren A; Klingberg E; Bengtsson A; Hansson M; Olsson S; Pin E; Klareskog L; Kapetanovic MC
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(5):673-684
Diversity and Clonality of T Cell Receptor Repertoire and Antigen Specificities in Small Joints of Early Rheumatoid Arthritis
Turcinov S; af Klint E; Van Schoubroeck B; Kouwenhoven A; Mia S; Chemin K; Wils H; Van Hove C; De Bondt A; Keustermans K; Van Houdt J; Reumers J; Felix N; Rao NL; Peeters P; Stevenaert F; Klareskog L; McKinnon M; Baker D; Suri A; Malmstroem V
Article: JOURNAL OF AUTOIMMUNITY. 2023;136:103022
The human bone marrow plasma cell compartment in rheumatoid arthritis-Clonal relationships and anti-citrulline autoantibody producing cells
Hensvold A; Horuluoglu B; Sahlstrom P; Thyagarajan R; Boada JSD; Hansson M; Mathsson-Alm L; Gerstner C; Sippl N; Israelsson L; Wedin R; Steen J; Klareskog L; Rethi B; Catrina AI; Diaz-Gallo L-M; Malmstrom V; Gronwall C
Article: BIOMOLECULES. 2023;13(4):630
Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation
Circiumaru A; Afonso MG; Wahamaa H; Krishnamurthy A; Hansson M; Mathsson-Alm L; Keszei M; Stalesen R; Ottosson L; de Vries C; Shelef MA; Malmstrom V; Klareskog L; Catrina AI; Gronwall C; Hensvold A; Rethi B
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(3):316-323
Occupational inhalable agents constitute major risk factors for rheumatoid arthritis, particularly in the context of genetic predisposition and smoking
Tang B; Liu Q; Ilar A; Wiebert P; Hagg S; Padyukov L; Klareskog L; Alfredsson L; Jiang X
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(2):164-170
Combination of Two Monoclonal Anti-Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase-4-Dependent Manner
Krishnamurthy A; Circiumaru A; Sun J; Kisten Y; Damberg P; Sakuraba K; Sandor K; Jarvoll P; Zhou T; Malmstrom V; Svensson CI; Hensvold A; Catrina AI; Klareskog L; Rethi B
Article: MOLECULAR IMMUNOLOGY. 2022;152:106-110
Five commercially-available antibodies react differentially with allelic forms of human HLA-DR beta chain
Houtman M; Dzebisashvili A; Dubnovitsky A; Kozhukh G; Ronnblom L; Klareskog L; Malmstrom V; Padyukov L
Article: RHEUMATOLOGY. 2022;61(12):4985-4990
Anti-citrullinated protein antibody specificities and pulmonary fibrosis in relation to genetic loci in early rheumatoid arthritis
Brink M; Ljung L; Hansson M; Ronnelid J; Holmdahl R; Skriner K; Serre G; Klareskog L; Rantapaa-Dahlqvist S
Article: NATURE GENETICS. 2022;54(11):1640-1651
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis
Ishigaki K; Sakaue S; Terao C; Luo Y; Sonehara K; Yamaguchi K; Amariuta T; Too CL; Laufer VA; Scott IC; Viatte S; Takahashi M; Ohmura K; Murasawa A; Hashimoto M; Ito H; Hammoudeh M; Al Emadi S; Masri BK; Halabi H; Badsha H; Uthman IW; Wu X; Lin L; Li T; Plant D; Barton A; Orozco G; Verstappen SMM; Bowes J; MacGregor AJ; Honda S; Koido M; Tomizuka K; Kamatani Y; Tanaka H; Tanaka E; Suzuki A; Maeda Y; Yamamoto K; Miyawaki S; Xie G; Zhang J; Amos CI; Keystone E; Wolbink G; Van der Horst-Bruinsma I; Cui J; Liao KP; Carroll RJ; Lee H-S; Bang S-Y; Siminovitch KA; de Vries N; Alfredsson L; Rantapaa-Dahlqvist S; Karlson EW; Bae S-C; Kimberly RP; Edberg JC; Mariette X; Huizinga T; Dieude P; Schneider M; Kerick M; Denny JC; Matsuda K; Matsuo K; Mimori T; Matsuda F; Fujio K; Tanaka Y; Kumanogoh A; Traylor M; Lewis CM; Eyre S; Xu H; Saxena R; Arayssi T; Kochi Y; Ikari K; Harigai M; Gregersen PK; Yamamoto K; Bridges SLJ; Padyukov L; Martin J; Klareskog L; Okada Y; Raychaudhuri S
Article: BIOLOGICAL PSYCHIATRY GLOBAL OPEN SCIENCE. 2022;2(4):368-378
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Watson HJ; Thornton LM; Yilmaz Z; Baker JH; Coleman JRI; Adan RAH; Alfredsson L; Andreassen OA; Ask H; Berrettini WH; Boehnke M; Boehm I; Boni C; Buehren K; Bulant J; Burghardt R; Chang X; Cichon S; Cone RD; Courtet P; Crow S; Crowley JJ; Danner UN; de Zwaan M; Dedoussis G; DeSocio JE; Dick DM; Dikeos D; Dina C; Djurovic S; Dmitrzak-Weglarz M; Docampo-Martinez E; Duriez P; Egberts K; Ehrlich S; Eriksson JG; Escaramis G; Esko T; Estivill X; Farmer A; Fernandez-Aranda F; Fichter MM; Foecker M; Foretova L; Forstner AJ; Frei O; Gallinger S; Giegling I; Giuranna J; Gonidakis F; Gorwood P; Gratacos M; Guillaume S; Guo Y; Hakonarson H; Hauser J; Havdahl A; Hebebrand J; Helder SG; Herms S; Herpertz-Dahlmann B; Herzog W; Hinney A; Huebel C; Hudson JI; Imgart H; Jamain S; Janout V; Jimenez-Murcia S; Jones IR; Julia A; Kalsi G; Kaminska D; Kaprio J; Karhunen L; Kas MJH; Keel PK; Kennedy JL; Keski-Rahkonen A; Kiezebrink K; Klareskog L; Klump KL; Knudsen GPS; La Via MC; Le Hellard S; Leboyer M; Li D; Lilenfeld L; Lin B; Lissowska J; Luykx J; Magistretti P; Maj M; Marsal S; Marshall CR; Mattingsdal M; Meulenbelt I; Micali N; Mitchell KS; Monteleone AM; Monteleone P; Myers R; Navratilova M; Ntalla I; O'Toole JK; Ophoff RA; Padyukov L; Pantel J; Papezova H; Pinto D; Raevuori A; Ramoz N; Reichborn-Kjennerud T; Ricca V; Ripatti S; Ripke S; Ritschel F; Roberts M; Rotondo A; Rujescu D; Rybakowski F; Scherag A; Scherer SW; Schmidt U; Scott LJ; Seitz J; Silen Y; Slachtova L; Slagboom PE; Slof-Op 't Landt MCT; Slopien A; Sorbi S; Swiatkowska B; Tortorella A; Tozzi F; Treasure J; Tsitsika A; Tyszkiewicz-Nwafor M; Tziouvas K; van Elburg AA; van Furth EF; Walton E; Widen E; Zerwas S; Zipfel S; Bergen AW; Boden JM; Brandt H; Crawford S; Halmi KA; Horwood LJ; Johnson C; Kaplan AS; Kaye WH; Mitchell JE; Olsen CM; Pearson JF; Pedersen NL; Strober M; Werge T; Whiteman DC; Woodside DB; Gordon S; Maguire S; Larsen JT; Parker R; Petersen LV; Jordan J; Kennedy M; Wade TD; Birgegard A; Lichtenstein P; Landen M; Martin NG; Mortensen PB; Breen G; Bulik CM
Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):203
Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis: results from the Swedish EIRA study
Hedenstierna L; Hedstrom AK; Klareskog L; Di Giuseppe D; Alfredsson L; Askling J; Ernestam S; Saevarsdottir S; Ljung L
Article: PAIN. 2022;163(8):1542-1559
Antibody-induced pain-like behavior and bone erosion: links to subclinical inflammation, osteoclast activity, and acid-sensing ion channel 3-dependent sensitization
Jurczak A; Delay L; Barbier J; Simon N; Krock E; Sandor K; Agalave NM; Rudjito R; Wigerblad G; Rogoz K; Briat A; Miot-Noirault E; Martinez-Martinez A; Bromme D; Gronwall C; Malmstrom V; Klareskog L; Khoury S; Ferreira T; Labrum B; Deval E; Miguel Jimenez-Andrade J; Marchand F; Svensson CI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(8):1085-1095
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Saevarsdottir S; Stefansdottir L; Sulem P; Thorleifsson G; Ferkingstad E; Rutsdottir G; Glintborg B; Westerlind H; Grondal G; Loft IC; Sorensen SB; Lie BA; Brink M; Arlestig L; Arnthorsson AO; Baecklund E; Banasik K; Bank S; Bjorkman LI; Ellingsen T; Erikstrup C; Frei O; Gjertsson I; Gudbjartsson DF; Gudjonsson SA; Halldorsson GH; Hendricks O; Hillert J; Hogdall E; Jacobsen S; Jensen DV; Jonsson H; Kastbom A; Kockum I; Kristensen S; Kristjansdottir H; Larsen MH; Linauskas A; Hauge E-M; Loft AG; Ludviksson BR; Lund SH; Markusson T; Masson G; Melsted P; Moore KHS; Munk H; Nielsen KR; Norddahl GL; Oddsson A; Olafsdottir TA; Olason PI; Olsson T; Ostrowski SR; Horslev-Petersen K; Rognvaldsson S; Sanner H; Silberberg GN; Stefansson H; Sorensen E; Sorensen IJ; Turesson C; Bergman T; Alfredsson L; Kvien TK; Brunak S; Steinsson K; Andersen V; Andreassen OA; Rantapaa-Dahlqvist S; Hetland ML; Klareskog L; Askling J; Padyukov L; Pedersen OB; Thorsteinsdottir U; Jonsdottir I; Stefansson K
Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):178
Investigation of the association between coffee and risk of RA-results from the Swedish EIRA study
Westerlind H; Dukuzimana J; Lu X; Alfredsson L; Klareskog L; Di Giuseppe D
Article: ACR OPEN RHEUMATOLOGY. 2022;4(6):492-502
Unmet Needs in Rheumatoid Arthritis: A Subgroup of Patients With High Levels of Pain, Fatigue, and Psychosocial Distress 3 Years After Diagnosis
Lindqvist J; Alfredsson L; Klareskog L; Lampa J; Westerlind H
Article: RHEUMATOLOGY. 2022;61(4):1680-1689
Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis
Yoosuf N; Maciejewski M; Ziemek D; Jelinsky SA; Folkersen L; Muller M; Sahlstrom P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Article: RMD OPEN. 2022;8(1):e002018
Allergic conditions and risk of rheumatoid arthritis: a Swedish case-control study
Kronzer VL; Westerlind H; Alfredsson L; Crowson CS; Klareskog L; Holmqvist M; Askling J
Article: FRONTIERS IN MEDICINE. 2022;9:774945
Rheumatic?-A Digital Diagnostic Decision Support Tool for Individuals Suspecting Rheumatic Diseases: A Multicenter Pilot Validation Study
Knevel R; Knitza J; Hensvold A; Circiumaru A; Bruce T; Evans S; Maarseveen T; Maurits M; Beaart-van de Voorde L; Simon D; Kleyer A; Johannesson M; Schett G; Huizinga T; Svanteson S; Lindfors A; Klareskog L; Catrina A
Article: RMD OPEN. 2022;8(1):e001800
Sleep problems in rheumatoid arthritis over 12 years from diagnosis: results from the Swedish EIRA study
Lyne L; Akerstedt T; Alfredsson L; Lehtonen T; Saevarsdottir S; Klareskog L; Westerlind H
Article: FRONTIERS IN MEDICINE. 2022;9:824501
Prospective Studies on the Risk of Rheumatoid Arthritis: The European Risk RA Registry
Studenic P; Hensvold A; Kleyer A; van der Helm-van Mil A; Pratt AG; Sieghart D; Kroenke G; Williams R; de Souza S; Karlfeldt S; Johannesson M; Krogh NS; Klareskog L; Catrina AI
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:804822
Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology
Sherina N; de Vries C; Kharlamova N; Sippl N; Jiang X; Brynedal B; Kindstedt E; Hansson M; Mathsson-Alm L; Israelsson L; Stalesen R; Saevarsdottir S; Holmdahl R; Hensvold A; Johannsen G; Eriksson K; Sallusto F; Catrina AI; Roennelid J; Groenwall C; Yucel-Lindberg T; Alfredsson L; Klareskog L; Piccoli L; Malmstroem V; Amara K; Lundberg K
Article: SCIENTIFIC REPORTS. 2021;11(1):24512
Biased TCR gene usage in citrullinated Tenascin C specific T-cells in rheumatoid arthritis
Sharma RK; Boddul SV; Yoosuf N; Turcinov S; Dubnovitsky A; Kozhukh G; Wermeling F; Kwok WW; Klareskog L; Malmstrom V
Article: RMD OPEN. 2021;7(3):e001987
Effects of the COVID-19 pandemic on patients with inflammatory joint diseases in Sweden: from infection severity to impact on care provision
Bower H; Frisell T; di Giuseppe D; Delcoigne B; Ahlenius G-M; Baecklund E; Chatzidionysiou K; Feltelius N; Forsblad-d'Elia H; Kastbom A; Klareskog L; Lindqvist E; Lindstrom U; Turesson C; Sjowall C; Askling J
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):209
Is tea consumption associated with reduction of risk of rheumatoid arthritis? A Swedish case-control study
Westerlind H; Palmqvist I; Saevarsdottir S; Alfredsson L; Klareskog L; Di Giuseppe D
Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(8):1086-1093
Impact of the COVID-19 pandemic on morbidity and mortality in patients with inflammatory joint diseases and in the general population: a nationwide Swedish cohort study
Bower H; Frisell T; Di Giuseppe D; Delcoigne B; Ahlenius G-M; Baecklund E; Chatzidionysiou K; Feltelius N; Forsblad-d'Elia H; Kastbom A; Klareskog L; Lindqvist E; Lindstrom U; Turesson C; Sjowall C; Askling J
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021;39(4):879-882
Rheumatoid arthritis autoantibodies and their association with age and sex
Pertsinidou E; Manivel VA; Westerlind H; Klareskog L; Alfredsson L; Mathsson-Alm L; Hansson M; Saevatsdottir S; Askling J; Ronnelid J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2021;50(4):271-279
Widespread non-joint pain in early rheumatoid arthritis
Schelin MEC; Westerlind H; Lindqvist J; Englid E; Israelsson L; Skillgate E; Klareskog L; Alfredsson L; Lampa J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2021;50(3):178-182
Social stressors and risk of rheumatoid arthritis and their relationship to known modifiable risk factors: results from the Swedish EIRA study
Hedenstierna L; Opava CH; Askling J; Jiang X; Ernestam S; Alfredsson L; Klareskog L; Saevarsdottir S
Article: SCIENCE IMMUNOLOGY. 2021;6(58):eabe0896
The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR
Lim JJ; Jones CM; Loh TJ; Ting YT; Zareie P; Loh KL; Felix NJ; Suri A; McKinnon M; Stevenaert F; Sharma RK; Klareskog L; Malmstrom V; Baker DG; Purcell AW; Reid HH; La Gruta NL; Rossjohn J
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):108
Age at menarche, age at natural menopause, and risk of rheumatoid arthritis - a Mendelian randomization study
Zhu J; Niu Z; Alfredsson L; Klareskog L; Padyukov L; Jiang X
Article: ARTHRITIS & RHEUMATOLOGY. 2021;73(2):203-211
Obesity-Related Traits and the Development of Rheumatoid Arthritis: Evidence From Genetic Data
Tang B; Shi H; Alfredsson L; Klareskog L; Padyukov L; Jiang X
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):46
The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study
Tan LK; Too CL; Diaz-Gallo LM; Wahinuddin S; Lau IS; Heselynn H; Nor-Shuhaila S; Gun SC; Eashwary M; Mohd-Shahrir MS; Ainon MM; Azmillah R; Muhaini O; Shahnaz M; Alfredsson L; Klareskog L; Padyukov L
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:707217
Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients
Houtman M; Hesselberg E; Ronnblom L; Klareskog L; Malmstrom V; Padyukov L
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:627986
A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis
Gronwall C; Liljefors L; Bang H; Hensvold AH; Hansson M; Mathsson-Alm L; Israelsson L; Joshua V; Svard A; Stalesen R; Titcombe PJ; Steen J; Piccoli L; Sherina N; Clavel C; Svenungsson E; Gunnarsson I; Saevarsdottir S; Kastbom A; Serre G; Alfredsson L; Malmstrom V; Ronnelid J; Catrina AI; Lundberg K; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2021;73(1):61-68
Respiratory Diseases as Risk Factors for Seropositive and Seronegative Rheumatoid Arthritis and in Relation to Smoking
Kronzer VL; Westerlind H; Alfredsson L; Crowson CS; Nyberg F; Tornling G; Klareskog L; Holmqvist M; Askling J
Article: JOURNAL OF TRANSLATIONAL AUTOIMMUNITY. 2021;4:100087
In vitro and ex vivo functional characterization of human HLA-DRB1*04 restricted T cell receptors
Boddul SV; Sharma RK; Dubnovitsky A; Raposo B; Gerstner C; Shen Y; Iyer VS; Kasza Z; Kwok WW; Winkler AR; Klareskog L; Malmstrom V; Bettini M; Wermeling F
Article: ARTHRITIS & RHEUMATOLOGY. 2020;72(10):1643-1657
Different Hierarchies of Anti-Modified Protein Autoantibody Reactivities in Rheumatoid Arthritis
Sahlstroem P; Hansson M; Steen J; Amara K; Titcombe PJ; Forsstrom B; Stalesen R; Israelsson L; Piccoli L; Lundberg K; Klareskog L; Mueller DL; Catrina AI; Skriner K; Malmstrom V; Gronwall C
Article: ARTHRITIS & RHEUMATOLOGY. 2020;72(10):1658-1667
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Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches
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Complex Relationships of Smoking, HLA-DRB1 Genes, and Serologic Profiles in Patients With Early Rheumatoid Arthritis: Update From a Swedish Population-Based Case-Control Study
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Sequencing of the MHC region defines HLA-DQA1 as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population
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Interplay between obesity and smoking with regard to RA risk
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Article: NATURE GENETICS. 2018;50(10):1366-1374
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes
Westra H-J; Martinez-Bonet M; Onengut-Gumuscu S; Lee A; Luol Y; Teslovich N; Worthington J; Martin J; Huizinga T; Klareskog L; Rantapaa-Dahlqvist S; Chen W-M; Quinlan A; Todd JA; Eyre S; Nigrovic PA; Regersen PKG; Rich SS; Raychaudhuri S
Article: JOURNAL OF AUTOIMMUNITY. 2018;92:47-56
Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint
Pieper J; Dubnovitsky A; Gerstner C; James EA; Rieck M; Kozhukh G; Tandre K; Pellegrino S; Gebe JA; Ronnblom L; Sandalova T; Kwok WW; Klareskog L; Buckner JH; Achour A; Malmstrom V
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2018;16(1):214
Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis
Engstrom M; Eriksson K; Lee L; Hermansson M; Johansson A; Nicholas AP; Gerasimcik N; Lundberg K; Klareskog L; Catrina AI; Yucel-Lindberg T
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2018;47(4):270-275
Anti-cyclic citrullinated peptide antibodies, other common autoantibodies, and smoking as risk factors for lymphoma in patients with rheumatoid arthritis
Baecklund E; Backlin C; Ronnelid J; Toes R; Huizinga TWJ; Ahlin E; Askling J; Hochberg FH; Klareskog L; Kay J; Smedby KE
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(7):970-972
Exposure to passive smoking and rheumatoid arthritis risk: results from the Swedish EIRA study
Hedstrom AK; Klareskog L; Alfredsson L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2018;48(6):1030-1045
Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection
Lloyd KA; Steen J; Amara K; Titcombe PJ; Israelsson L; Lundstrom SL; Zhou D; Zubarev RA; Reed E; Piccoli L; Gabay C; Lanzavecchia A; Baeten D; Lundberg K; Mueller DL; Klareskog L; Malmstrom V; Gronwall C
Article: ARTHRITIS CARE AND RESEARCH. 2018;70(4):499-509
Occupation and Risk of Developing Rheumatoid Arthritis: Results From a Population-Based Case-Control Study
Ilar A; Alfredsson L; Wiebert P; Klareskog L; Bengtsson C
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2018;33(4):415-423
Smoking and susceptibility to rheumatoid arthritis in a Swedish population-based case-control study
Hedstrom AK; Stawiarz L; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(2):203-211
Anticitrullinated protein/peptide antibody multiplexing defines an extended group of ACPA-positive rheumatoid arthritis patients with distinct genetic and environmental determinants
Ronnelid J; Hansson M; Mathsson-Alm L; Cornillet M; Reed E; Jakobsson P-J; Alfredsson L; Holmdahl R; Skriner K; Serre G; Lundberg K; Klareskog L
Article: ARTHRITIS CARE AND RESEARCH. 2018;70(2):205-212
Dietary Intake of Polyunsaturated Fatty Acids and Pain in Spite of Inflammatory Control Among Methotrexate-Treated Early Rheumatoid Arthritis Patients
Lourdudoss C; Di Giuseppe D; Wolk A; Westerlind H; Klareskog L; Alfredsson L; van Vollenhoven RF; Lampa J
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:451
A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Human with Arthritis
Tong D; Lonnblom E; Yau ACY; Nandakumar KS; Liang B; Ge C; Viljanen J; Li L; Balan M; Klareskog L; Chagin AS; Gjertsson I; Kihlberg J; Zhao M; Holmdahl R
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:3033
Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis
Lloyd KA; Wigerblad G; Sahlstrom P; Garimella MG; Chemin K; Steen J; Titcombe PJ; Marklein B; Zhou D; Stalesen R; Ossipova E; Lundqvist C; Ekwall O; Ronnelid J; Mueller DL; Karlsson MCI; Kaplan MJ; Skriner K; Klareskog L; Wermeling F; Malmstrom V; Gronwall C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(11):1845-1852
Oral contraceptives, breastfeeding and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study
Orellana C; Saevarsdottir S; Klareskog L; Karlson EW; Alfredsson L; Bengtsson C
Article: JOURNAL OF AUTOIMMUNITY. 2017;84:29-45
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis
Gronwall C; Amara K; Hardt U; Krishnamurthy A; Steen J; Engstrom M; Sun M; Ytterberg AJ; Zubarev RA; Scheel-Toellner D; Greenberg JD; Klareskog L; Catrina AI; Malmstrom V; Silverman GJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(10):1755-1763
H1N1 vaccination in Sjogren's syndrome triggers polyclonal B cell activation and promotes autoantibody production
Brauner S; Folkersen L; Kvarnstrom M; Meisgen S; Petersen S; Franzen-Malmros M; Mofors J; Brokstad KA; Klareskog L; Jonsson R; Westerberg LS; Trollmo C; Malmstrom V; Ambrosi A; Kuchroo VK; Nordmark G; Wahren-Herlenius M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(9):1529-1536
Anticollagen type II antibodies are associated with an acute onset rheumatoid arthritis phenotype and prognosticate lower degree of inflammation during 5 years follow-up
Manivel VA; Mullazehi M; Padyukov L; Westerlind H; Klareskog L; Alfredsson L; Saevarsdottir S; Ronnelid J
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2017;174(9):850-858
Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa
Duncan L; Yilmaz Z; Gaspar H; Walters R; Goldstein J; Anttila V; Bulik-Sullivan B; Ripke S; Thornton L; Daly M; Sullivan PF; Zeggini E; Breen G; Bulik CM; Adan R; Alfredsson L; Ando T; Andreassen O; Aschauer H; Baker J; Barrett J; Bencko V; Bergen A; Berrettini W; Birgegard A; Boni C; Perica VB; Brandt H; Burghardt R; Carlberg L; Cassina M; Cesta C; Cichon S; Clementi M; Cohen-Woods S; Coleman J; Cone R; Courtet P; Crawford S; Crow S; Crowley J; Danner U; Davis O; de Zwaan M; Dedoussis G; Degortes D; DeSocio J; Dick D; Dikeos D; Dina C; Ding B; Dmitrzak-Weglarz M; Docampo E; Egberts K; Ehrlich S; Escaramis G; Esko T; Espeseth T; Estivill X; Favaro A; Fernandez-Aranda F; Fichter M; Finan C; Fischer K; Floyd J; Foecker M; Foretova L; Forzan M; Fox C; Franklin C; Gaborieau V; Gallinger S; Gambaro G; Giegling I; Gonidakis F; Gorwood P; Gratacos M; Guillaume S; Guo Y; Hakonarson H; Halmi K; Harrison R; Hatzikotoulas K; Hauser J; Hebebrand J; Helder S; Hendriks J; Herms S; Herpertz-Dahlmann B; Herzog W; Hilliard C; Huckins L; Hudson J; Huemer J; Imgart H; Inoko H; Jall S; Jamain S; Janout V; Jimenez-Murcia S; Johnson C; Jordan J; Julia A; Jureus A; Kalsi G; Kaplan A; Kaprio J; Karhunen L; Karwautz A; Kas M; Kaye W; Kennedy M; Kennedy J; Keski-Rahkonen A; Kiezebrink K; Kim Y-R; Klareskog L; Klump K; Knudsen GP; Koeleman B; Koubek D; La Via M; Landen M; Le Hellard S; Leboyer M; Levitan R; Li D; Lichtenstein P; Lilenfeld L; Lissowska J; Lundervold A; Magistretti P; Maj M; Mannik K; Marsal S; Kaminska D; Martin N; Mattingsdal M; McDevitt S; McGuffin P; Merl E; Metspalu A; Meulenbelt I; Micali N; Mitchell J; Mitchell K; Monteleone P; Monteleone AM; Montgomery G; Mortensen P; Munn-Chernoff M; Mueller T; Nacmias B; Navratilova M; Nilsson I; Norring C; Ntalla I; Ophoff R; O'Toole J; Palotie A; Pantel J; Papezova H; Parker R; Pinto D; Rabionet R; Raevuori A; Rajewski A; Ramoz N; Rayner NW; Reichborn-Kjennerud T; Ricca V; Ripatti S; Ritschel F; Roberts M; Rotondo A; Rujescu D; Rybakowski F; Santonastaso P; Scherag A; Scherer S; Schmidt U; Schork N; Schosser A; Scott L; Seitz J; Slachtova L; Sladek R; Slagboom PE; Slof-Op 't Landt M; Slopien A; Smith T; Soranzo N; Sorbi S; Southam L; Steen V; Strengman E; Strober M; Szatkiewicz J; Szeszenia-Dabrowska N; Tachmazidou I; Tenconi E; Tortorella A; Tozzi F; Treasure J; Tschop M; Tsitsika A; Tziouvas K; van Elburg A; van Furth E; Wade T; Wagner G; Walton E; Watson H; Wichmann H-E; Widen E; Woodside DB; Yanovski J; Yao S; Zerwas S; Zipfel S; Thornton L; Hinney A; Daly M; Sullivan PF; Zeggini E; Breen G; Bulik CM
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):182
IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis
Lundstrom SL; Hensvold AH; Rutishauser D; Klareskog L; Ytterberg AJ; Zubarev RA; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):71
DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis
Meng W; Zhu Z; Jiang X; Too CL; Uebe S; Jagodic M; Kockum I; Murad S; Ferrucci L; Alfredsson L; Zou H; Klareskog L; Feinberg AP; Ekstrom TJ; Padyukov L; Liu Y
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):19
Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis
Shchetynsky K; Diaz-Gallo L-M; Folkersen L; Hensvold AH; Catrina AI; Berg L; Klareskog L; Padyukov L
Article: RMD OPEN. 2017;3(1):e000324
Physical workload is associated with increased risk of rheumatoid arthritis: results from a Swedish population-based case-control study.
Zeng P; Klareskog L; Alfredsson L; Bengtsson C
Article: RMD OPEN. 2017;3(2):e000475
Relationship between shift work and the onset of rheumatoid arthritis.
Hedström AK; Åkerstedt T; Klareskog L; Alfredsson L
Article: RMD OPEN. 2017;3(2):e000488
Working in cold environment and risk of developing rheumatoid arthritis: results from the Swedish EIRA case-control study.
Zeng P; Bengtsson C; Klareskog L; Alfredsson L
Article: OSTEOARTHRITIS AND CARTILAGE. 2017;25(1):157-165
An in vivo cross-linkable hyaluronan gel with inherent anti-inflammatory properties reduces OA cartilage destruction in female mice subjected to cruciate ligament transection
Aulin C; Lundback P; Palmblad K; Klareskog L; Harris HE
Article: ARTHRITIS & RHEUMATOLOGY. 2017;69(1):58-69
Differences in the Spectrum of Anti-Citrullinated Protein Antibody Fine Specificities Between Malaysian and Swedish Patients With Rheumatoid Arthritis: Implications for Disease Pathogenesis
Too CL; Murad S; Hansson M; Alm LM; Dhaliwal JS; Holmdahl R; Jakobsson P-J; Alfredsson L; Klareskog L; Ronnelid J; Padyukov L
Article: GENES AND IMMUNITY. 2017;18(1):48-56
VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis
Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Petit-Teixeira E; Cornelis F; Saoudi A; Fournie GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Article: GENOME MEDICINE. 2016;8(1):124
High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis
Gomez-Cabrero D; Almgren M; Sjoholm LK; Hensvold AH; Ringh MV; Tryggvadottir R; Kere J; Scheynius A; Acevedo N; Reinius L; Taub MA; Montano C; Aryee MJ; Feinberg JI; Feinberg AP; Tegner J; Klareskog L; Catrina AI; Ekstrom TJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(10):1891-1898
Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA
van Heemst J; Hensvold AH; Jiang X; van Steenbergen H; Klareskog L; Huizinga TWJ; van der Helm-van Mil A; Catrina AI; Toes REM; Lundberg K; van der Woude D
Article: MOLECULAR MEDICINE. 2016;22:322-328
Integration of Known DNA, RNA and Protein Biomarkers Provides Prediction of Anti-TNF Response in Rheumatoid Arthritis: Results from the COMBINE Study
Folkersen L; Brynedal B; Diaz-Gallo LM; Ramskold D; Shchetynsky K; Westerlind H; Sundstrom Y; Schepis D; Hensvold A; Vivar N; Eloranta M-L; Ronnblom L; Brunak S; Malmstrom V; Catrina A; Moerch UGW; Klareskog L; Padyukov L; Berg L
Article: NATURE COMMUNICATIONS. 2016;7:12460
Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
Sieberts SK; Zhu F; Garcia-Garcia J; Stahl E; Pratap A; Pandey G; Pappas D; Aguilar D; Anton B; Bonet J; Eksi R; Fornes O; Guney E; Li H; Marin MA; Panwar B; Planas-Iglesias J; Poglayen D; Cui J; Falcao AO; Suver C; Hoff B; Balagurusamy VSK; Dillenberger D; Neto EC; Norman T; Aittokallio T; Ammad-ud-din M; Azencott C-A; Bellon V; Boeva V; Bunte K; Chheda H; Cheng L; Corander J; Dumontier M; Goldenberg A; Gopalacharyulu P; Hajiloo M; Hidru D; Jaiswal A; Kaski S; Khalfaoui B; Khan SA; Kramer ER; Marttinen P; Mezlini AM; Molparia B; Pirinen M; Saarela J; Samwald M; Stoven V; Tang H; Tang J; Torkamani A; Vert J-P; Wang B; Wang T; Wennerberg K; Wineinger NE; Xiao G; Xie Y; Yeung R; Zhan X; Zhao C; Greenberg J; Kremer J; Michaud K; Barton A; Coenen M; Mariette X; Miceli C; Shadick N; Weinblatt M; de Vries N; Tak PP; Gerlag D; Huizinga TWJ; Kurreeman F; Allaart CF; Bridges SLJ; Criswell L; Moreland L; Klareskog L; Saevarsdottir S; Padyukov L; Gregersen PK; Friend S; Plenge R; Stolovitzky G; Oliva B; Guan Y; Mangravite LM
Article: ARTHRITIS CARE AND RESEARCH. 2016;68(8):1061-1068
Remaining Pain in Early Rheumatoid Arthritis Patients Treated With Methotrexate
Altawil R; Saevarsdottir S; Wedren S; Alfredsson L; Klareskog L; Lampa J
Article: NATURE GENETICS. 2016;48(7):803-810
A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases
Han B; Pouget JG; Slowikowski K; Stahl E; Lee CH; Diogo D; Hu X; Park YR; Kim E; Gregersen PK; Dahlqvist SR; Worthington J; Martin J; Eyre S; Klareskog L; Huizinga T; Chen W-M; Onengut-Gumuscu S; Rich SS; Wray NR; Raychaudhuri S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(6):997-1002
Occupational exposure to textile dust increases the risk of rheumatoid arthritis: results from a Malaysian population-based case-control study
Too CL; Muhamad NA; Ilar A; Padyukov L; Alfredsson L; Klareskog L; Murad S; Bengtsson C
Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(5):1124-1135
A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis
Chemin K; Pollastro S; James E; Ge C; Albrecht I; Herrath J; Gerstner C; Tandre K; Rizzi TS; Ronnblom L; Catrina A; Holmdahl R; Klareskog L; de Vries N; Malmstrom V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):721-729
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
Krishnamurthy A; Joshua V; Hensvold AH; Jin T; Sun M; Vivar N; Ytterberg AJ; Engstrom M; Fernandes-Cerqueira C; Amara K; Magnusson M; Wigerblad G; Kato J; Jimenez-Andrade JM; Tyson K; Rapecki S; Lundberg K; Catrina S-B; Jakobsson P-J; Svensson C; Malmstrom V; Klareskog L; Wahamaa H; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):730-738
Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism
Wigerblad G; Bas DB; Fernades-Cerqueira C; Krishnamurthy A; Nandakumar KS; Rogoz K; Kato J; Sandor K; Su J; Miguel Jimenez-Andrade J; Finn A; Farinotti AB; Amara K; Lundberg K; Holmdahl R; Jakobsson P-J; Malmstrom V; Catrina AI; Klareskog L; Svensson CI
Article: ARTHRITIS RESEARCH & THERAPY. 2016;18:43
Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis
Brink M; Hansson M; Mathsson-Alm L; Wijayatunga P; Verheul MK; Trouw LA; Holmdahl R; Ronnelid J; Klareskog L; Rantapaa-Dahlqvist S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(2):356-361
Changes in the anticitrullinated peptide antibody response in relation to therapeutic outcome in early rheumatoid arthritis: results from the SWEFOT trial
Kastbom A; Forslind K; Ernestam S; Geborek P; Karlsson JA; Petersson IF; Saevarsdottir S; Klareskog L; van Vollenhoven RF; Lundberg K
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(1):317-320
Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study
Yarwood A; Viatte S; Okada Y; Plenge R; Yamamoto K; Barton A; Symmons D; Raychaudhuri S; Klareskog L; Gregersen P; Worthington J; Eyre S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(1):183-189
Familial aggregation of arthritis-related diseases in seropositive and seronegative rheumatoid arthritis: a register-based case-control study in Sweden
Frisell T; Hellgren K; Alfredsson L; Raychaudhuri S; Klareskog L; Askling J
Article: PLOS ONE. 2016;11(5):e0155956
Prevalence of Periodontitis in Patients with Established Rheumatoid Arthritis: A Swedish Population Based Case-Control Study
Eriksson K; Nise L; Kats A; Luttropp E; Catrina AI; Askling J; Jansson L; Alfredsson L; Klareskog L; Lundberg K; Yucel-Lindberg T
Article: RHEUMATOLOGY. 2016;55(1):149-155
An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis
Jiang X; Kallberg H; Chen Z; Arlestig L; Rantapaa-Dahlqvist S; Davila S; Klareskog L; Padyukov L; Alfredsson L
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17:358
Parity influences the severity of ACPA-negative early rheumatoid arthritis: a cohort study based on the Swedish EIRA material
Pikwer M; Orellana C; Kallberg H; Pikwer A; Turesson C; Klareskog L; Alfredsson L; Saevarsdottir S; Bengtsson C
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17:317
Higher education is associated with a better rheumatoid arthritis outcome concerning for pain and function but not disease activity: results from the EIRA cohort and Swedish rheumatology register
Jiang X; Sandberg MEC; Saevarsdottir S; Klareskog L; Alfredsson L; Bengtsson C
Article: ARTHRITIS & RHEUMATOLOGY. 2015;67(10):2611-2623
Interactions Between Amino Acid-Defined Major Histocompatibility Complex Class II Variants and Smoking in Seropositive Rheumatoid Arthritis
Kim K; Jiang X; Cui J; Lu B; Costenbader KH; Sparks JA; Bang S-Y; Lee H-S; Okada Y; Raychaudhuri S; Alfredsson L; Bae S-C; Klareskog L; Karlson EW
Article: NATURE GENETICS. 2015;47(9):1085-1090
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases
Lenz TL; Deutsch AJ; Han B; Hu X; Okada Y; Eyre S; Knapp M; Zhernakova A; Huizinga TWJ; Abecasis G; Becker J; Boeckxstaens GE; Chen W-M; Franke A; Gladman DD; Gockel I; Gutierrez-Achury J; Martin J; Nair RP; Noethen MM; Onengut-Gumuscu S; Rahman P; Rantapaa-Dahlqvist S; Stuart PE; Tsoi LC; van Heel DA; Worthington J; Wouters MM; Klareskog L; Elder JT; Gregersen PK; Schumacher J; Rich SS; Wijmenga C; Sunyaev SR; de Bakker PIW; Raychaudhuri S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(9):1772-1777
Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation
Ytterberg AJ; Joshua V; Reynisdottir G; Tarasova NK; Rutishauser D; Ossipova E; Hensvold AH; Eklund A; Skold CM; Grunewald J; Malmstrom V; Jakobsson PJ; Ronnelid J; Padyukov L; Zubarev RA; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(8):1522-1529
Improved performance of epidemiologic and genetic risk models for rheumatoid arthritis serologic phenotypes using family history
Sparks JA; Chen C-Y; Jiang X; Askling J; Hiraki LT; Malspeis S; Klareskog L; Alfredsson L; Costenbader KH; Karlson EW
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):155
Targeting of anti-citrullinated protein/peptide antibodies in rheumatoid arthritis using peptides mimicking endogenously citrullinated fibrinogen antigens
Fernandes-Cerqueira C; Ossipova E; Gunasekera S; Hansson M; Mathsson L; Catrina AI; Sommarin Y; Klareskog L; Lundberg K; Ronnelid J; Goransson U; Jakobsson P-J
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):125
Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis
Kokkonen H; Brink M; Hansson M; Lassen E; Mathsson-Alm L; Holmdahl R; Ronnelid J; Klareskog L; Rantapaa-Dahlqvist S
Article: ARTHRITIS & RHEUMATOLOGY. 2015;67(8):2032-2037
Associations With Smoking and Shared Epitope Differ Between IgA- and IgG-Class Antibodies to Cyclic Citrullinated Peptides in Early Rheumatoid Arthritis
Svard A; Skogh T; Alfredsson L; Ilar A; Klareskog L; Bengtsson C; Kastbom A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(5):904-907
Recent infections are associated with decreased risk of rheumatoid arthritis: a population-based case-control study
Sandberg MEC; Bengtsson C; Klareskog L; Alfredsson L; Saevarsdottir S
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2015;30(5):449-457
Postmenopausal hormone therapy and the risk of rheumatoid arthritis: results from the Swedish EIRA population-based case-control study
Orellana C; Saevarsdottir S; Klareskog L; Karlson EW; Alfredsson L; Bengtsson C
Article: CLINICAL IMMUNOLOGY. 2015;158(1):19-28
Gene-gene interaction and RNA splicing profiles of MAP2K4 gene in rheumatoid arthritis
Shchetynsky K; Protsyuk D; Ronninger M; Diaz-Gallo L-M; Klareskog L; Padyukov L
Article: NATURE COMMUNICATIONS. 2015;6:6651
Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss
Harre U; Lang SC; Pfeifle R; Rombouts Y; Fruhbeisser S; Amara K; Bang H; Lux A; Koeleman CA; Baum W; Dietel K; Groehn F; Malmstroem V; Klareskog L; Kroenke G; Kocijan R; Nimmerjahn F; Toes REM; Herrmann M; Scherer HU; Schett G
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(3):e15
A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides
Bossini-Castillo L; de Kovel C; Kallberg H; van 't Slot R; Italiaander A; Coenen M; Tak PP; Posthumus MD; Wijmenga C; Huizinga T; van der Helm-van Mil AHM; Stoeken-Rijsbergen G; Rodriguez-Rodriguez L; Balsa A; Gonzalez-Alvaro I; Angel Gonzalez-Gay M; Gomez-Vaquero C; Franke B; Vermeulen S; van der Horst-Bruinsma IE; Dijkmans BAC; Wolbink GJ; Ophoff RA; Maehlen MT; van Riel P; Merriman M; Klareskog L; Lie BA; Merriman T; Crusius JBA; Brouwer E; Martin J; de Vries N; Toes R; Padyukov L; Koeleman BPC
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(3):579-586
Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles
Wagner CA; Sokolove J; Lahey LJ; Bengtsson C; Saevarsdottir S; Alfredsson L; Delanoy M; Lindstrom TM; Walker RP; Bromberg R; Chandra PE; Binder SR; Klareskog L; Robinson WH
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(3):e13
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci
Kim K; Bang S-Y; Lee H-S; Cho S-K; Choi C-B; Sung Y-K; Kim T-H; Jun J-B; Yoo DH; Kang YM; Kim S-K; Suh C-H; Shim S-C; Lee S-S; Lee J; Chung WT; Choe J-Y; Shin HD; Lee J-Y; Han B-G; Nath SK; Eyre S; Bowes J; Pappas DA; Kremer JM; Gonzalez-Gay MA; Rodriguez-Rodriguez L; Arlestig L; Okada Y; Diogo D; Liao KP; Karlson EW; Raychaudhuri S; Rantapaa-Dahlqvist S; Martin J; Klareskog L; Padyukov L; Gregersen PK; Worthington J; Greenberg JD; Plenge RM; Bae S-C
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):25
Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage
Brink M; Verheul MK; Ronnelid J; Berglin E; Holmdahl R; Toes REM; Klareskog L; Trouw LA; Rantapaa-Dahlqvist S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(2):375-380
Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins
Hensvold AH; Magnusson PKE; Joshua V; Hansson M; Israelsson L; Ferreira R; Jakobsson P-J; Holmdahl R; Hammarstrom L; Malmstrom V; Askling J; Klareskog L; Catrina AI
Article: ARTHRITIS & RHEUMATOLOGY. 2015;67(2):352-362
To What Extent Is the Familial Risk of Rheumatoid Arthritis Explained by Established Rheumatoid Arthritis Risk Factors?
Jiang X; Frisell T; Askling J; Karlson EW; Klareskog L; Alfredsson L; Kallberg H
Article: PLOS ONE. 2015;10(4):e0122271
TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits
Diogo D; Bastarache L; Liao KP; Graham RR; Fulton RS; Greenberg JD; Eyre S; Bowes J; Cui J; Lee A; Pappas DA; Kremer JM; Barton A; Coenen MJH; Franke B; Kiemeney LA; Mariette X; Richard-Miceli C; Canhao H; Fonseca JE; de Vries N; Tak PP; Crusius JBA; Nurmohamed MT; Kurreeman F; Mikuls TR; Okada Y; Stahl EA; Larson DE; Deluca TL; O'Laughlin M; Fronick CC; Fulton LL; Kosoy R; Ransom M; Bhangale TR; Ortmann W; Cagan A; Gainer V; Karlson EW; Kohane I; Murphy SN; Martin J; Zhernakova A; Klareskog L; Padyukov L; Worthington J; Mardis ER; Seldin MF; Gregersen PK; Behrens T; Raychaudhuri S; Denny JC; Plenge RM
Article: CELL REPORTS. 2014;9(4):1417-1429
A Role for Noncoding Variation in Schizophrenia
Roussos P; Mitchell AC; Voloudakis G; Fullard JF; Pothula VM; Tsang J; Stahl EA; Georgakopoulos A; Ruderfer DM; Charney A; Okada Y; Siminovitch KA; Worthington J; Padyukov L; Klareskog L; Gregersen PK; Plenge RM; Raychaudhuri S; Fromer M; Purcell SM; Brennand KJ; Robakis NK; Schadt EE; Akbarian S; Sklar P
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(11):2029-2033
Overweight decreases the chance of achieving good response and low disease activity in early rheumatoid arthritis
Sandberg MEC; Bengtsson C; Kallberg H; Wesley A; Klareskog L; Alfredsson L; Saevarsdottir S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(10):1761-1768
Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies
Jiang X; Trouw LA; van Wesemael TJ; Shi J; Bengtsson C; Kallberg H; Malmstrom V; Israelsson L; Hreggvidsdottir H; Verduijn W; Klareskog L; Alfredsson L; Huizinga TWJ; Toes REM; Lundberg K; van der Woude D
Article: MOLECULAR PSYCHIATRY. 2014;19(10):1085-1094
A genome-wide association study of anorexia nervosa
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Article: ARTHRITIS CARE AND RESEARCH. 2014;66(10):1582-1586
Smokeless Tobacco (Moist Snuff) Use and the Risk of Developing Rheumatoid Arthritis: Results From a Case-Control Study
Jiang X; Alfredsson L; Klareskog L; Bengtsson C
Article: ARTHRITIS RESEARCH & THERAPY. 2014;16(4):414
Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis
Snir O; Gomez-Cabrero D; Montes A; Perez-Pampin E; Gomez-Reino JJ; Seddighzadeh M; Klich KU; Israelsson L; Ding B; Catrina AI; Holmdahl R; Alfredsson L; Klareskog L; Tegner J; Gonzalez A; Malmstrom V; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2014;16(4):R167
Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint
Ossipova E; Cerqueira CF; Reed E; Kharlamova N; Israelsson L; Holmdahl R; Nandakumar KS; Engstrom M; Harre U; Schett G; Catrina AI; Malmstrom V; Sommarin Y; Klareskog L; Jakobsson P-J; Lundberg K
Article: HUMAN MOLECULAR GENETICS. 2014;23(15):4177-4184
IgA measurements in over 12 000 Swedish twins reveal sex differential heritability and regulatory locus near CD30L
Viktorin A; Frankowiack M; Padyukov L; Chang Z; Melen E; Saaf A; Kull I; Klareskog L; Hammarstrom L; Magnusson PKE
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(8):1541-1544
Patients with regular physical activity before onset of rheumatoid arthritis present with milder disease
Sandberg MEC; Wedren S; Klareskog L; Lundberg IE; Opava CH; Alfredsson L; Saevarsdottir S
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(7):1712-1722
Citrulline-Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy
James EA; Rieck M; Pieper J; Gebe JA; Yue BB; Tatum M; Peda M; Sandin C; Klareskog L; Malmstrom V; Buckner JH
Article: JOURNAL OF INTERNAL MEDICINE. 2014;275(6):640-651
The HLA locus contains novel foetal susceptibility alleles for congenital heart block with significant paternal influence
Meisgen S; Ostberg T; Salomonsson S; Ding B; Eliasson H; Malarstig A; Alfredsson L; Klareskog L; Hamsten A; Olsson T; Axelsson T; Gadler F; Jonzon A; Sonesson S-E; Kockum I; Wahren-Herlenius M
Article: ARTHRITIS CARE AND RESEARCH. 2014;66(6):844-851
Association Between Life Events and Rheumatoid Arthritis: Results From a Population-Based Case-Control Study
Wesley A; Bengtsson C; Skillgate E; Saevarsdottir S; Theorell T; Holmqvist M; Klareskog L; Alfredsson L; Wedren S
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2014;94(4):522-532
Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity
Han B; Diogo D; Eyre S; Kallberg H; Zhernakova A; Bowes J; Padyukov L; Okada Y; Gonzalez-Gay MA; Rantapaa-Dahlqvist S; Martin J; Huizinga TWJ; Plenge RM; Worthington J; Gregersen PK; Klareskog L; de Bakker PIW; Raychaudhuri S
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2014;94(4):485-495
GeMes, Clusters of DNA Methylation under Genetic Control, Can Inform Genetic and Epigenetic Analysis of Disease
Liu Y; Li X; Aryee MJ; Ekstrom TJ; Padyukov L; Klareskog L; Vandiver A; Moore AZ; Tanaka T; Ferrucci L; Fallin MD; Feinberg AP
Article: MODERN RHEUMATOLOGY. 2014;24(2):271-274
Silica exposure is associated with an increased risk of developing ACPA-positive rheumatoid arthritis in an Asian population: evidence from the Malaysian MyEIRA case-control study
Yahya A; Bengtsson C; Larsson P; Too CL; Mustafa AN; Abdullah NA; Muhamad NA; Klareskog L; Murad S; Alfredsson L
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(3):513-522
Features of the Synovium of Individuals at Risk of Developing Rheumatoid Arthritis
de Hair MJH; van de Sande MGH; Ramwadhdoebe TH; Hansson M; Landewe R; van der Leij C; Maas M; Serre G; van Schaardenburg D; Klareskog L; Gerlag DM; van Baarsen LGM; Tak PP
Article: GENES AND IMMUNITY. 2014;15(2):107-114
The influence of polygenic risk scores on heritability of anti-CCP level in RA
Cui J; Taylor KE; Lee YC; Kallberg H; Weinblatt ME; Coblyn JS; Klareskog L; Criswell LA; Gregersen PK; Shadick NA; Plenge RM; Karlson EW
Article: NATURE. 2014;506(7488):376-381
Genetics of rheumatoid arthritis contributes to biology and drug discovery
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Article: PLOS ONE. 2014;9(11):e113924
IgG Antibodies to Cyclic Citrullinated Peptides Exhibit Profiles Specific in Terms of IgG Subclasses, Fc-Glycans and a Fab-Peptide Sequence
Lundstrom SL; Fernandes-Cerqueira C; Ytterberg AJ; Ossipova E; Hensvold AH; Jakobsson P-J; Malmstrom V; Catrina AI; Klareskog L; Lundberg K; Zubarev RA
Article: PLOS ONE. 2014;9(9):e104382
Accelerating Translational Research by Clinically Driven Development of an Informatics Platform-A Case Study
Abugessaisa I; Saevarsdottir S; Tsipras G; Lindblad S; Sandin C; Nikamo P; Stahle M; Malmstrom V; Klareskog L; Tegner J
Article: PLOS ONE. 2014;9(2):e87645
Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene
Okada Y; Diogo D; Greenberg JD; Mouassess F; Achkar WAL; Fulton RS; Denny JC; Gupta N; Mirel D; Gabriel S; Li G; Kremer JM; Pappas DA; Carroll RJ; Eyler AE; Trynka G; Stahl EA; Cui J; Saxena R; Coenen MJH; Guchelaar H-J; Huizinga TWJ; Dieude P; Mariette X; Barton A; Canhao H; Fonseca JE; de Vries N; Tak PP; Moreland LW; Bridges SLJ; Miceli-Richard C; Choi HK; Kamatani Y; Galan P; Lathrop M; Raj T; De Jager PL; Raychaudhuri S; Worthington J; Padyukov L; Klareskog L; Siminovitch KA; Gregersen PK; Mardis ER; Arayssi T; Kazkaz LA; Plenge RM
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(1):31-39
Structural Changes and Antibody Enrichment in the Lungs Are Early Features of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis
Reynisdottir G; Karimi R; Joshua V; Olsen H; Hensvold AH; Harju A; Engstrom M; Grunewald J; Nyren S; Eklund A; Klareskog L; Skold CM; Catrina AI
Article: ARTHRITIS & RHEUMATOLOGY. 2013;65(12):3058-3062
Identification of BACH2 and RAD51B as Rheumatoid Arthritis Susceptibility Loci in a Meta-Analysis of Genome-Wide Data
McAllister K; Yarwood A; Bowes J; Orozco G; Viatte S; Diogo D; Hocking LJ; Steer S; Wordsworth P; Wilson AG; Morgan AW; Kremer JM; Pappas D; Gregersen P; Klareskog L; Plenge R; Barton A; Greenberg J; Worthington J; Eyre S
Article: ARTHRITIS & RHEUMATOLOGY. 2013;65(11):2773-2782
Familial Risks and Heritability of Rheumatoid Arthritis Role of Rheumatoid Factor/Anti-Citrullinated Protein Antibody Status, Number and Type of Affected Relatives, Sex, and Age
Frisell T; Holmqvist M; Kallberg H; Klareskog L; Alfredsson L; Askling J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(8):1287-1294
Impact of intravenous abatacept on synovitis, osteitis and structural damage in patients with rheumatoid arthritis and an inadequate response to methotrexate: the ASSET randomised controlled trial
Conaghan PG; Durez P; Alten RE; Burmester G-R; Tak PP; Klareskog L; Catrina AI; DiCarlo J; Gaillez C; Le Bars M; Zhou X; Peterfy C
Article: ARTHRITIS & RHEUMATOLOGY. 2013;65(7):1702-1712
Autoantibodies to Posttranslationally Modified Type II Collagen as Potential Biomarkers for Rheumatoid Arthritis
Strollo R; Ponchel F; Malmstrom V; Rizzo P; Bombardieri M; Wenham CY; Landy R; Perret D; Watt F; Corrigall VM; Winyard PG; Pozzilli P; Conaghan PG; Panayi GS; Klareskog L; Emery P; Nissim A
Article: ARTHRITIS CARE AND RESEARCH. 2013;65(7):1147-1156
Association of Environmental and Genetic Factors and Gene-Environment Interactions With Risk of Developing Rheumatoid Arthritis
Karlson EW; Ding B; Keenan BT; Liao K; Costenbader KH; Klareskog L; Alfredsson L; Chibnik LB
Article: ARTHRITIS CARE AND RESEARCH. 2013;65(7):1190-1196
Ambient Air Pollution Exposures and Risk of Rheumatoid Arthritis
Hart JE; Kaellberg H; Laden F; Costenbader KH; Yanosky JD; Klareskog L; Alfredsson L; Karlson EW
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(6):1018-1025
HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus
Lundstrom E; Gustafsson JT; Jonsen A; Leonard D; Zickert A; Elvin K; Sturfelt G; Nordmark G; Bengtsson AA; Sundin U; Kallberg H; Sandling JK; Syvanen A-C; Klareskog L; Gunnarsson I; Ronnblom L; Padyukov L; Svenungsson E
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(6):888-894
Ambient air pollution exposures and risk of rheumatoid arthritis: results from the Swedish EIRA case-control study
Hart JE; Kaellberg H; Laden F; Bellander T; Costenbader KH; Holmqvist M; Klareskog L; Alfredsson L; Karlson EW
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(5):652-658
Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile.
Lundberg K; Bengtsson C; Kharlamova N; Reed E; Jiang X; Kallberg H; Pollak-Dorocic I; Israelsson L; Kessel C; Padyukov L; Holmdahl R; Alfredsson L; Klareskog L
Article: MODERN RHEUMATOLOGY. 2013;:1-5
Silica exposure is associated with an increased risk of developing ACPA-positive rheumatoid arthritis in an Asian population: evidence from the Malaysian MyEIRA case-control study.
Yahya A; Bengtsson C; Larsson P; Too CL; Mustafa AN; Abdullah NA; Muhamad NA; Klareskog L; Murad S; Alfredsson L
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2013;11:85
Implementation of the CDC translational informatics platform - from genetic variants to the national Swedish Rheumatology Quality Register
Abugessaisa I; Gomez-Cabrero D; Snir O; Lindblad S; Klareskog L; Malmstrom V; Tegner J
Article: ARTHRITIS & RHEUMATOLOGY. 2013;65(4):899-910
Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis
Brink M; Hansson M; Mathsson L; Jakobsson P-J; Holmdahl R; Hallmans G; Stenlund H; Ronnelid J; Klareskog L; Rantapaa-Dahlqvist S
Article: GENES AND IMMUNITY. 2013;14(2):83-89
Genetic variation in the serotonin receptor gene affects immune responses in rheumatoid arthritis
Snir O; Hesselberg E; Amoudruz P; Klareskog L; Zarea-Ganji I; Catrina A; Padyukov L; Malmstrom V; Seddighzadeh M
Article: NATURE BIOTECHNOLOGY. 2013;31(2):142-147
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
Liu Y; Aryee MJ; Padyukov L; Fallin MD; Hesselberg E; Runarsson A; Reinius L; Acevedo N; Taub M; Ronninger M; Shchetynsky K; Scheynius A; Kere J; Alfredsson L; Klareskog L; Ekstrom TJ; Feinberg AP
Article: TWIN RESEARCH AND HUMAN GENETICS. 2013;16(1):317-329
The Swedish Twin Registry: establishment of a biobank and other recent developments.
Magnusson PKE; Almqvist C; Rahman I; Ganna A; Viktorin A; Walum H; Halldner L; Lundström S; Ullén F; Långström N; Larsson H; Nyman A; Gumpert CH; Råstam M; Anckarsäter H; Cnattingius S; Johannesson M; Ingelsson E; Klareskog L; de Faire U; Pedersen NL; Lichtenstein P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2013;92(1):15-27
Rare, Low-Frequency, and Common Variants in the Protein-Coding Sequence of Biological Candidate Genes from GWASs Contribute to Risk of Rheumatoid Arthritis
Diogo D; Kurreeman F; Stahl EA; Liao KP; Gupta N; Greenberg JD; Rivas MA; Hickey B; Flannick J; Thomson B; Guiducci C; Ripke S; Adzhubey I; Barton A; Kremer JM; Alfredsson L; Sunyaev S; Martin J; Zhernakova A; Bowes J; Eyre S; Siminovitch KA; Gregersen PK; Worthington J; Klareskog L; Padyukov L; Raychaudhuri S; Plenge RM
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2013;42(5):337-343
Regional differences regarding risk of developing rheumatoid arthritis in Stockholm County, Sweden: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study
Kallberg H; Vieira V; Holmqvist M; Hart JE; Costenbader KH; Bengtsson C; Klareskog L; Karlson EW; Alfredsson L
Article: PLOS GENETICS. 2013;9(12):e1003993
Quantifying Missing Heritability at Known GWAS Loci
Gusev A; Bhatia G; Zaitlen N; Vilhjalmsson BJ; Diogo D; Stahl EA; Gregersen PK; Worthington J; Klareskog L; Raychaudhuri S; Plenge RM; Pasaniuc B; Price AL
Article: PLOS ONE. 2013;8(6):e66456
Identification of the Tyrosine-Protein Phosphatase Non-Receptor Type 2 as a Rheumatoid Arthritis Susceptibility Locus in Europeans
Cobb JE; Plant D; Flynn E; Tadjeddine M; Dieude P; Cornelis F; Arlestig L; Dahlqvist SR; Goulielmos G; Boumpas DT; Sidiropoulos P; Krintel SB; Ornbjerg LM; Hetland ML; Klareskog L; Haeupl T; Filer A; Buckley CD; Raza K; Witte T; Schmidt RE; FitzGerald O; Veale D; Eyre S; Worthington J
Article: ARTHRITIS CARE AND RESEARCH. 2013;65(1):107-112
Association between body mass index and anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis: Results from a population-based case-control study
Wesley A; Bengtsson C; Elkan A-C; Klareskog L; Alfredsson L; Wedren S
Article: NATURE GENETICS. 2012;44(12):1336-1340
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
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Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(6):R250
Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis
Too CL; Murad S; Dhaliwal JS; Larsson P; Jiang X; Ding B; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(5):R201
Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides
Hansson M; Mathsson L; Schlederer T; Israelsson L; Matsson P; Nogueira L; Jakobsson P-J; Lundberg K; Malmstrom V; Serre G; Holmdahl R; Nystrand M; Klareskog L; Ronnelid J
Article: ARTHRITIS & RHEUMATOLOGY. 2012;64(8):2482-2488
Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis
Snir O; Backlund J; Bostrom J; Andersson I; Kihlberg J; Buckner JH; Klareskog L; Holmdahl R; Malmstrom V
Article: JOURNAL OF RHEUMATOLOGY. 2012;39(8):1509-1516
Variants Within STAT Genes Reveal Association with Anticitrullinated Protein Antibody-negative Rheumatoid Arthritis in 2 European Populations
Seddighzadeh M; Gonzalez A; Ding B; Ferreiro-Iglesias A; Gomez-Reino JJ; Klareskog L; Alfredsson L; Dunussi-Joannopoulos K; Clark JD; Padyukov L
Article: MODERN RHEUMATOLOGY. 2012;22(4):524-531
Smoking is associated with an increased risk of developing ACPA-positive but not ACPA-negative rheumatoid arthritis in Asian populations: evidence from the Malaysian MyEIRA case-control study
Yahya A; Bengtsson C; Lai TC; Larsson PT; Mustafa AN; Abdullah NA; Muhamad N; Hussein H; Klareskog L; Alfredsson L; Murad S
Article: ARTHRITIS & RHEUMATOLOGY. 2012;64(7):2078-2084
Very high levels of anti-citrullinated protein antibodies are associated with HLA-DRB1*15 non-shared epitope allele in patients with rheumatoid arthritis
Laki J; Lundstrom E; Snir O; Ronnelid J; Ganji I; Catrina AI; Bengtsson C; Saevarsdottir S; Wick MC; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(3):R100
Anti-type II collagen antibodies are associated with early radiographic destruction in rheumatoid arthritis
Mullazehi M; Wick MC; Klareskog L; van Vollenhoven R; Ronnelid J
Article: JOURNAL OF CLINICAL INVESTIGATION. 2012;122(5):1791-1802
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin
Harre U; Georgess D; Bang H; Bozec A; Axmann R; Ossipova E; Jakobsson P-J; Baum W; Nimmerjahn F; Szarka E; Sarmay G; Krumbholz G; Neumann E; Toes R; Scherer H-U; Catrina AI; Klareskog L; Jurdic P; Schett G
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(2):R89
Smoking interacts with HLA-DRB1 shared epitope in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis: results from the Malaysian Epidemiological Investigation of Rheumatoid Arthritis (MyEIRA)
Too CL; Yahya A; Murad S; Dhaliwal JS; Larsson PT; Muhamad NA; Abdullah NA; Mustafa AN; Klareskog L; Alfredsson L; Padyukov L; Bengtsson C
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(1):R41
Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study
Sverdrup BM; Kallberg H; Klareskog L; Alfredsson L
Article: NATURE GENETICS. 2012;44(3):291-296
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
Raychaudhuri S; Sandor C; Stahl EA; Freudenberg J; Lee H-S; Jia X; Alfredsson L; Padyukov L; Klareskog L; Worthington J; Siminovitch KA; Bae S-C; Plenge RM; Gregersen PK; de Bakker PIW
Article: PHARMACOGENETICS AND GENOMICS. 2012;22(1):1-9
Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis
Dervieux T; Wessels JAM; Kremer JM; Padyukov L; Seddighzadeh M; Saevarsdottir S; van Vollenhoven RF; Klareskog L; Huizinga TW; Guchelaar H-J
Article: PLOS GENETICS. 2011;7(8):e1002254
Pervasive Sharing of Genetic Effects in Autoimmune Disease
Cotsapas C; Voight BF; Rossin E; Lage K; Neale BM; Wallace C; Abecasis GR; Barrett JC; Behrens T; Cho J; De Jager PL; Elder JT; Graham RR; Gregersen P; Klareskog L; Siminovitch KA; van Heel DA; Wijmenga C; Worthington J; Todd JA; Hafler DA; Rich SS; Daly MJ
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2011;19(8):908-914
Variants of gene for microsomal prostaglandin E2 synthase show association with disease and severe inflammation in rheumatoid arthritis
Korotkova M; Daha NA; Seddighzadeh M; Ding B; Catrina AI; Lindblad S; Huizinga TWJ; Toes REM; Alfredsson L; Klareskog L; Jakobsson P-J; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(8):1407-1414
Sick leave and disability pension before and after initiation of antirheumatic therapies in clinical practice
Neovius M; Simard JF; Klareskog L; Askling J
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2011;26(7):557-561
GEIRA: gene-environment and gene-gene interaction research application
Ding B; Kallberg H; Klareskog L; Padyukov L; Alfredsson L
Article: ARTHRITIS RESEARCH & THERAPY. 2011;13(2):R65
Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers
Saevarsdottir S; Ding B; Steinsson K; Grondal G; Valdimarsson H; Alfredsson L; Klareskog L; Padyukov L
Article: PLOS GENETICS. 2011;7(4):e1001378
GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma
Smedby KE; Foo JN; Skibola CF; Darabi H; Conde L; Hjalgrim H; Kumar V; Chang ET; Rothman N; Cerhan JR; Brooks-Wilson AR; Rehnberg E; Irwan ID; Ryder LP; Brown PN; Bracci PM; Agana L; Riby J; Cozen W; Davis S; Hartge P; Morton LM; Severson RK; Wang SS; Slager SL; Fredericksen ZS; Novak AJ; Kay NE; Habermann TM; Armstrong B; Kricker A; Milliken S; Purdue MP; Vajdic CM; Boyle P; Lan Q; Zahm SH; Zhang Y; Zheng T; Leach S; Spinelli JJ; Smith MT; Chanock SJ; Padyukov L; Alfredsson L; Klareskog L; Glimelius B; Melbye M; Liu ET; Adami H-O; Humphreys K; Liu J
Article: PLOS ONE. 2011;6(3):e17880
Effects of GSTM1 in Rheumatoid Arthritis; Results from the Swedish EIRA study
Lundstrom E; Hartshorne T; Li K; Lindblad S; Wick MC; Bengtsson C; Alfredsson L; Klareskog L; Padyukov L
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2011;29(2):238-247
Assessment of long-term safety and efficacy of etanercept in a 5-year extension study in patients with rheumatoid arthritis
Klareskog L; Gaubitz M; Rodriguez-Valverde V; Malaise M; Dougados M; Wajdula J
Article: JOURNAL OF RHEUMATOLOGY. 2011;38(3):446-449
The Functional Polymorphism 844 A>G in Fc_αRI (CD89) Does Not Contribute to Systemic Sclerosis or Rheumatoid Arthritis Susceptibility
Broen JCA; Coenen MJH; Rueda B; Witte T; Padyukov L; Klareskog L; Hesselstrand R; Wuttge DM; Simeon C; Ortego-Centeno N; Gonzalez-Gay MA; Pros A; Hunzelman N; Riemekasten G; Kreuter A; Vonk M; Scorza R; Beretta L; Airo P; van Riel PLCM; Kimberly R; Martin J; Edberg J; Radstake TRDJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):508-511
Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke
Kallberg H; Ding B; Padyukov L; Bengtsson C; Ronnelid J; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):423-427
Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials
van de Sande MGH; Gerlag DM; Lodde BM; van Baarsen LGM; Alivernini S; Codullo V; Felea I; Vieira-Sousa E; Fearon U; Reece R; Montecucco C; Veale DJ; Pitzalis C; Emery P; Klareskog L; McInnes IB; Tak PP
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):516-519
Generalisability of clinical registers used for drug safety and comparative effectiveness research: coverage of the Swedish Biologics Register
Neovius M; Simard JF; Sundstrom A; Jacobsson L; Geborek P; Saxne T; Feltelius N; Klareskog L; Askling J
Article: PLOS GENETICS. 2011;7(2):e1002004
Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci
Zhernakova A; Stahl EA; Trynka G; Raychaudhuri S; Festen EA; Franke L; Westra H-J; Fehrmann RSN; Kurreeman FAS; Thomson B; Gupta N; Romanos J; McManus R; Ryan AW; Turner G; Brouwer E; Posthumus MD; Remmers EF; Tucci F; Toes R; Grandone E; Mazzilli MC; Rybak A; Cukrowska B; Coenen MJH; Radstake TRDJ; van Riel PLCM; Li Y; de Bakker PIW; Gregersen PK; Worthington J; Siminovitch KA; Klareskog L; Huizinga TWJ; Wijmenga C; Plenge RM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(2):259-265
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis
Padyukov L; Seielstad M; Ong RTH; Ding B; Ronnelid J; Seddighzadeh M; Alfredsson L; Klareskog L
Article: PLOS ONE. 2011;6(8):e22547
The Genetic Structure of the Swedish Population
Humphreys K; Grankvist A; Leu M; Hall P; Liu J; Ripatti S; Rehnstroem K; Groop L; Klareskog L; Ding B; Gronberg H; Xu J; Pedersen NL; Lichtenstein P; Mattingsdal M; Andreassen OA; O'Dushlaine C; Purcell SM; Sklar P; Sullivan PF; Hultman CM; Palmgren J; Magnusson PKE
Article: RHEUMATOLOGY. 2011;50(1):204-213
Ten years with biologics: to whom do data on effectiveness and safety apply?
Simard JF; Arkema EV; Sundstrom A; Geborek P; Saxne T; Baecklund E; Coster L; Dackhammar C; Jacobsson L; Feltelius N; Lindblad S; Rantapaa-Dahlqvist S; Klareskog L; van Vollenhoven RF; Neovius M; Askling J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2011;40(1):8-15
Small-area variations in sales of TNF inhibitors in Sweden between 2000 and 2009
Neovius M; Sundstrom A; Simard JF; Wettermark B; Cars T; Feltelius N; Askling J; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2011;63(1):26-36
Patients With Early Rheumatoid Arthritis Who Smoke Are Less Likely to Respond to Treatment With Methotrexate and Tumor Necrosis Factor Inhibitors Observations From the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Register Cohorts
Saevarsdottir S; Wedren S; Seddighzadeh M; Bengtsson C; Wesley A; Lindblad S; Askling J; Alfredsson L; Klareskog L
Article: PLOS ONE. 2011;6(6):e21069
Shared Epitope Alleles Remain A Risk Factor for Anti-Citrullinated Proteins Antibody (ACPA) - Positive Rheumatoid Arthritis in Three Asian Ethnic Groups
Chun-Lai T; Padyukov L; Dhaliwal JS; Lundstrom E; Yahya A; Muhamad NA; Klareskog L; Alfredsson L; Larsson PT; Murad S
Article: PLOS ONE. 2010;5(12):e14326
Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome
Coenen MJH; Enevold C; Barrera P; Schijvenaars MMVAP; Toonen EJM; Scheffer H; Padyukov L; Kastbom A; Klareskog L; Barton A; Kievit W; Rood MJ; Jansen TL; Swinkels D; van Riel PLCM; Franke B; Bendtzen K; Radstake TRDJ
Article: JOURNAL OF INTERNAL MEDICINE. 2010;268(6):578-585
Rapid increase in myocardial infarction risk following diagnosis of rheumatoid arthritis amongst patients diagnosed between 1995 and 2006
Holmqvist ME; Wedren S; Jacobsson LTH; Klareskog L; Nyberg F; Rantapaa-Dahlqvist S; Alfredsson L; Askling J
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(11):3196-3210
Effect of Interactions of Glutathione S-Transferase T1, M1, and P1 and HMOX1 Gene Promoter Polymorphisms With Heavy Smoking on the Risk of Rheumatoid Arthritis
Keenan BT; Chibnik LB; Cui J; Ding B; Padyukov L; Kallberg H; Bengtsson C; Klareskog L; Alfredsson L; Karlson EW
Article: NATURE GENETICS. 2010;42(11):996-999
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
Hueffmeier U; Uebe S; Ekici AB; Bowes J; Giardina E; Korendowych E; Juneblad K; Apel M; McManus R; Ho P; Bruce IN; Ryan AW; Behrens F; Lascorz J; Boehm B; Traupe H; Lohmann J; Gieger C; Wichmann H-E; Herold C; Steffens M; Klareskog L; Wienker TF; FitzGerald O; Alenius G-M; McHugh NJ; Novelli G; Burkhardt H; Barton A; Reis A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(10):1831-1833
Common vaccinations among adults do not increase the risk of developing rheumatoid arthritis: results from the Swedish EIRA study
Bengtsson C; Kapetanovic MC; Kallberg H; Sverdrup B; Nordmark B; Klareskog L; Alfredsson L
Article: NATURE GENETICS. 2010;42(9):777-U69
Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency
Ferreira RC; Pan-Hammarstrom Q; Graham RR; Gateva V; Fontan G; Lee AT; Ortmann W; Urcelay E; Fernandez-Arquero M; Nunez C; Jorgensen G; Ludviksson BR; Koskinen S; Haimila K; Clark HF; Klareskog L; Gregersen PK; Behrens TW; Hammarstrom L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(8):1548-1553
Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers
Plant D; Flynn E; Mbarek H; Dieude P; Cornelis F; Arlestig L; Dahlqvist SR; Goulielmos G; Boumpas DT; Sidiropoulos P; Johansen JS; Ornbjerg LM; Hetland ML; Klareskog L; Filer A; Buckley CD; Raza K; Witte T; Schmidt RE; Worthington J
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(7):1849-1861
Rheumatoid Arthritis Risk Allele PTPRC Is Also Associated With Response to Anti-Tumor Necrosis Factor α Therapy
Cui J; Saevarsdottir S; Thomson B; Padyukov L; van der Helm-van Mil AHM; Nititham J; Hughes LB; de Vries N; Raychaudhuri S; Alfredsson L; Askling J; Wedren S; Ding B; Guiducci C; Wolbink GJ; Crusius JBA; van der Horst-Bruinsma IE; Herenius M; Weinblatt ME; Shadick NA; Worthington J; Batliwalla F; Kern M; Morgan AW; Wilson AG; Isaacs JD; Hyrich K; Seldin MF; Moreland LW; Behrens TW; Allaart CF; Criswell LA; Huizinga TWJ; Tak PP; Bridges SLJ; Toes REM; Barton A; Klareskog L; Gregersen PK; Karlson EW; Plenge RM
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2010;18(7):821-826
Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis
Seddighzadeh M; Korotkova M; Kallberg H; Ding B; Daha N; Kurreeman FAS; Toes REM; Huizinga TW; Catrina AI; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(7):1870-1880
The Programmed Death 1/Programmed Death Ligand 1 Inhibitory Pathway Is Up-Regulated in Rheumatoid Synovium and Regulates Peripheral T Cell Responses in Human and Murine Arthritis
Raptopoulou AP; Bertsias G; Makrygiannakis D; Verginis P; Kritikos I; Tzardi M; Klareskog L; Catrina AI; Sidiropoulos P; Boumpas DT
Article: PLOS ONE. 2010;5(6):e11310
The Gene Expression Profile in the Synovium as a Predictor of the Clinical Response to Infliximab Treatment in Rheumatoid Arthritis
Lindberg J; Wijbrandts CA; van Baarsen LG; Nader G; Klareskog L; Catrina A; Thurlings R; Vervoordeldonk M; Lundeberg J; Tak PP
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(6):1077-1085
Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk
Karlson EW; Chibnik LB; Kraft P; Cui J; Keenan BT; Ding B; Raychaudhuri S; Klareskog L; Alfredsson L; Plenge RM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(6):1072-1076
Silica exposure among male current smokers is associated with a high risk of developing ACPA-positive rheumatoid arthritis
Stolt P; Yahya A; Bengtsson C; Kallberg H; Ronnelid J; Lundberg I; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(6):1129-1135
Golimumab in patients with active rheumatoid arthritis despite methotrexate therapy: 52-week results of the GO-FORWARD study
Keystone E; Genovese MC; Klareskog L; Hsia EC; Hall S; Miranda PC; Pazdur J; Bae S-C; Palmer W; Xu S; Rahman MU
Article: NATURE GENETICS. 2010;42(6):508-514
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
Stahl EA; Raychaudhuri S; Remmers EF; Xie G; Eyre S; Thomson BP; Li Y; Kurreeman FAS; Zhernakova A; Hinks A; Guiducci C; Chen R; Alfredsson L; Amos CI; Ardlie KG; Barton A; Bowes J; Brouwer E; Burtt NP; Catanese JJ; Coblyn J; Coenen MJH; Costenbader KH; Criswell LA; Crusius JBA; Cui J; de Bakker PIW; De Jager PL; Ding B; Emery P; Flynn E; Harrison P; Hocking LJ; Huizinga TWJ; Kastner DL; Ke X; Lee AT; Liu X; Martin P; Morgan AW; Padyukov L; Posthumus MD; Radstake TRDJ; Reid DM; Seielstad M; Seldin MF; Shadick NA; Steer S; Tak PP; Thomson W; van der Helm-van Mil AHM; van der Horst-Bruinsma IE; van der Schoot CE; van Riel PLCM; Weinblatt ME; Wilson AG; Wolbink GJ; Wordsworth BP; Wijmenga C; Karlson EW; Toes REM; de Vries N; Begovich AB; Worthington J; Siminovitch KA; Gregersen PK; Klareskog L; Plenge RM
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(5):1236-1245
Protection Against Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis Is Predominantly Associated With HLA-DRB1*1301 A Meta-Analysis of HLA-DRB1 Associations With Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis in Four European Populations
van der Woude D; Lie BA; Lundstrom E; Balsa A; Feitsma AL; Houwing-Duistermaat JJ; Verduijn W; Nordang GBN; Alfredsson L; Klareskog L; Pascual-Salcedo D; Gonzalez-Gay MA; Lopez-Nevot MA; Valero F; Roep BO; Huizinga TWJ; Kvien TK; Martin J; Padyukov L; de Vries RRP; Toes REM
Article: PROTEOMICS - CLINICAL APPLICATIONS. 2010;4(5):511-518
MS analysis of rheumatoid arthritic synovial tissue identifies specific citrullination sites on fibrinogen
Hermansson M; Artemenko K; Ossipova E; Eriksson H; Lengqvist J; Makrygiannakis D; Catrina AI; Nicholas AP; Klareskog L; Savitski M; Zubarev RA; Jakobsson P-J
Article: NATURE GENETICS. 2010;42(5):426-429
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
Radstake TRDJ; Gorlova O; Rueda B; Martin J-E; Alizadeh BZ; Palomino-Morales R; Coenen MJ; Vonk MC; Voskuyl AE; Schuerwegh AJ; Broen JC; van Riel PLCM; van't Slot R; Italiaander A; Ophoff RA; Riemekasten G; Hunzelmann N; Simeon CP; Ortego-Centeno N; Gonzalez-Gay MA; Gonzalez-Escribano MF; Airo P; van Laar J; Herrick A; Worthington J; Hesselstrand R; Smith V; de Keyser F; Houssiau F; Chee MM; Madhok R; Shiels P; Westhovens R; Kreuter A; Kiener H; de Baere E; Witte T; Padykov L; Klareskog L; Beretta L; Scorza R; Lie BA; Hoffmann-Vold A-M; Carreira P; Varga J; Hinchcliff M; Gregersen PK; Lee AT; Ying J; Han Y; Weng S-F; Amos CI; Wigley FM; Hummers L; Nelson JL; Agarwal SK; Assassi S; Gourh P; Tan FK; Koeleman BPC; Arnett FC; Martin J; Mayes MD
Article: PLOS ONE. 2010;5(2):e9315
Analysis of Neuropeptide S Receptor Gene (NPSR1) Polymorphism in Rheumatoid Arthritis
D'Amato M; Zucchelli M; Seddighzadeh M; Anedda F; Lindblad S; Kere J; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2010;12(6):R211
Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study
Visvanathan S; Rahman MU; Keystone E; Genovese M; Klareskog L; Hsia E; Mack M; Buchanan J; Elashoff M; Wagner C
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(1):44-52
Antibodies to Several Citrullinated Antigens Are Enriched in the Joints of Rheumatoid Arthritis Patients
Snir O; Widhe M; Hermansson M; von Spee C; Lindberg J; Hensen S; Lundberg K; Engstrom A; Venables PJW; Toes REM; Holmdahl R; Klareskog L; Malmstrom V
Article: SCIENCE TRANSLATIONAL MEDICINE. 2009;1(10):10ra21
A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
Jagodic M; Colacios C; Nohra R; Dejean AS; Beyeen AD; Khademi M; Casemayou A; Lamouroux L; Duthoit C; Papapietro O; Sjoholm L; Bernard I; Lagrange D; Dahlman I; Lundmark F; Oturai AB; Soendergaard HB; Kemppinen A; Saarela J; Tienari PJ; Harbo HF; Spurkland A; Ramagopalan SV; Sadovnick DA; Ebers GC; Seddighzadeh M; Klareskog L; Alfredsson L; Padyukov L; Hillert J; Clanet M; Edan G; Fontaine B; Fournie GJ; Kockum I; Saoudi A; Olsson T
Article: NATURE GENETICS. 2009;41(12):1319-1324
Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis
Mahdi H; Fisher BA; Kallberg H; Plant D; Malmstrom V; Ronnelid J; Charles P; Ding B; Alfredsson L; Padyukov L; Symmons DPM; Venables PJ; Klareskog L; Lundberg K
Article: NATURE GENETICS. 2009;41(12):1313-1318
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
Raychaudhuri S; Thomson BP; Remmers EF; Eyre S; Hinks A; Guiducci C; Catanese JJ; Xie G; Stahl EA; Chen R; Alfredsson L; Amos CI; Ardlie KG; Barton A; Bowes J; Burtt NP; Chang M; Coblyn J; Costenbader KH; Criswell LA; Crusius JBA; Cui J; De Jager PL; Ding B; Emery P; Flynn E; Harrison P; Hocking LJ; Huizinga TWJ; Kastner DL; Ke X; Kurreeman FAS; Lee AT; Liu X; Li Y; Martin P; Morgan AW; Padyukov L; Reid DM; Seielstad M; Seldin MF; Shadick NA; Steer S; Tak PP; Thomson W; van der Helm-van Mil AHM; van der Horst-Bruinsma IE; Weinblatt ME; Wilson AG; Wolbink GJ; Wordsworth P; Altshuler D; Karlson EW; Toes REM; de Vries N; Begovich AB; Siminovitch KA; Worthington J; Klareskog L; Gregersen PK; Daly MJ; Plenge RM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(44):18680-18685
Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases
Rioux JD; Goyette P; Vyse TJ; Hammarstroem L; Fernando MMA; Green T; De Jager PL; Foisy S; Wang J; de Bakker PIW; Leslie S; McVean G; Padyukov L; Alfredsson L; Annese V; Hafler DA; Pan-Hammarstroem Q; Matell R; Sawcer SJ; Compston AD; Cree BAC; Mirel DB; Daly MJ; Behrens TW; Klareskog L; Gregersen PK; Oksenberg JR; Hauser SL
Article: EPIDEMIOLOGY. 2009;20(6):896-901
Dietary Fish and Fish Oil and the Risk of Rheumatoid Arthritis
Rosell M; Wesley A-M; Rydin K; Klareskog L; Alfredsson L
Article: MOLECULAR MEDICINE. 2009;15(11-12):371-383
European Population Genetic Substructure: Further Definition of Ancestry Informative Markers for Distinguishing among Diverse European Ethnic Groups
Tian C; Kosoy R; Nassir R; Lee A; Villoslada P; Klareskog L; Hammarstrom L; Garchon H-J; Pulver AE; Ransom M; Gregersen PK; Seldin MF
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(11):3180-3189
Cancer Risk in Patients With Rheumatoid Arthritis Treated With Anti-Tumor Necrosis Factor α Therapies Does the Risk Change With the Time Since Start of Treatment?
Askling J; van Vollenhoven RF; Granath F; Raaschou P; Fored CM; Baecklund E; Dackhammar C; Feltelius N; Coster L; Geborek P; Jacobsson LT; Lindblad S; Rantapaa-Dahlqvist S; Saxne T; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(10):2861-2869
No Increased Occurrence of Ischemic Heart Disease Prior to the Onset of Rheumatoid Arthritis Results From Two Swedish Population-Based Rheumatoid Arthritis Cohorts
Holmqvist ME; Wedren S; Jacobsson LTH; Klareskog L; Nyberg F; Rantapaa-Dahlqvist S; Alfredsson L; Askling J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2009;613(1-3):155-162
Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice
Svelander L; Erlandsson-Harris H; Astner L; Grabowska U; Klareskog L; Lindstrom E; Hewitt E
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(6):789-796
Golimumab, a human antibody to tumour necrosis factor α given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study
Keystone EC; Genovese MC; Klareskog L; Hsia EC; Hall ST; Miranda PC; Pazdur J; Bae S-C; Palmer W; Zrubek J; Wiekowski M; Visvanathan S; Wu Z; Rahman MU
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(6):1597-1603
Gene-Environment Interaction Between the DRB1 Shared Epitope and Smoking in the Risk of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis
Lundstrom E; Kallberg H; Alfredsson L; Klareskog L; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(5):736-743
Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles
Snir O; Widhe M; von Spee C; Lindberg J; Padyukov L; Lundberg K; Engstrom A; Venables PJ; Lundeberg J; Holmdahl R; Klareskog L; Malmstrom V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(5):648-653
Anti-tumour necrosis factor therapy in rheumatoid arthritis and risk of malignant lymphomas: relative risks and time trends in the Swedish Biologics Register
Askling J; Baecklund E; Granath F; Geborek P; Fored M; Backlin C; Bertilsson L; Coster L; Jacobsson LT; Lindblad S; Lysholm J; Rantapaa-Dahlqvist S; Saxne T; van Vollenhoven R; Klareskog L; Feltelius N
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(5):1250-1254
The PRL-1149 G/T Polymorphism and Rheumatoid Arthritis Susceptibility
Lee YC; Raychaudhuri S; Cui J; De Vivo I; Ding B; Alfredsson L; Padyukov L; Costenbader KH; Selelstad M; Graham RR; Klareskog L; Gregersen PK; Plenge RM; Karlson EW
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(4):924-930
Opposing Effects of HLA-DRB1*13 Alleles on the Risk of Developing Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis
Lundstrom E; Kallberg H; Smolnikova M; Ding B; Ronnelid J; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(3):653-660
Specific Association of Type 1 Diabetes Mellitus With Anti-Cyclic Citrullinated Peptide-Positive Rheumatoid Arthritis
Liao KP; Gunnarsson M; Kallberg H; Ding B; Plenge RM; Padyukov L; Karlson EW; Klareskog L; Askling J; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(2):222-227
Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies
Kallberg H; Jacobsen S; Bengtsson C; Pedersen M; Padyukov L; Garred P; Frisch M; Karlson EW; Klareskog L; Alfredsson L
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(1):30-38
Different Patterns of Associations With Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis in the Extended Major Histocompatibility Complex Region
Ding B; Padyukov L; Lundstrom E; Seielstad M; Plenge RM; Oksenberg JR; Gregersen PK; Alfredsson L; Klareskog L
Article: ARTHRITIS RESEARCH & THERAPY. 2009;11(3):R81
Evaluation of arthroscopy and macroscopic scoring
Af Klint E; Catrina AI; Matt P; Neregrad P; Lampa J; Ulfgren A-K; Klareskog L; Lindblad S
Article: ARTHRITIS RESEARCH & THERAPY. 2009;11(3):R76
Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis
Hueber W; Tomooka BH; Batliwalla F; Li W; Monach PA; Tibshirani RJ; Van Vollenhoven RF; Lampa J; Saito K; Tanaka Y; Genovese MC; Klareskog L; Gregersen PK; Robinson WH
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2008;339(2):165-174
Serial re-challenge with influenza vaccine as a tool to study individual immune responses
Vallerskog T; Gaines H; Feldman A; Culbert E; Klareskog L; Malmstrom V; Trollmo C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(10):1444-1447
Improvements in clinical response between 12 and 24 weeks in patients with rheumatoid arthritis on etanercept therapy with or without methotrexate
Kavanaugh A; Klareskog L; van der Heijde D; Li J; Freundlich B; Hooper M
Article: NATURE GENETICS. 2008;40(10):1216-1223
Common variants at CD40 and other loci confer risk of rheumatoid arthritis
Raychaudhuri S; Remmers EF; Lee AT; Hackett R; Guiducci C; Burtt NP; Gianniny L; Korman BD; Padyukov L; Kurreeman FAS; Chang M; Catanese JJ; Ding B; Wong S; Mil AHMVDH-V; Neale BM; Coblyn J; Cui J; Tak PP; Wolbink GJ; Crusius JBA; van der Horst-Bruinsma IE; Criswell LA; Amos CI; Seldin MF; Kastner DL; Ardlie KG; Alfredsson L; Costenbader KH; Altshuler D; Huizinga TWJ; Shadick NA; Weinblatt ME; de Vries N; Worthington J; Seielstad M; Toes REM; Karlson EW; Begovich AB; Klareskog L; Gregersen PK; Daly MJ; Plenge RM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(10):1488-1492
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells
Makrygiannakis D; Hermansson M; Ulfgren A-K; Nicholas AP; Zendman AJW; Eklund A; Grunewald J; Skold CM; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(9):1267-1270
Level of radiographic damage and radiographic progression are determinants of physical function: a longitudinal analysis of the TEMPO trial
van der Heijde D; Landewe R; van Vollenhoven R; Fatenejad S; Klareskog L
Article: CLINICAL IMMUNOLOGY. 2008;128(3):374-381
Identification of CTLA-4 isoforms produced by alternative splicing and their association with myasthenia gravis
Gu M; Kakoulidou M; Giscombe R; Pirskanen R; Lefvert AK; Klareskog L; Wang X
Article: ARTHRITIS & RHEUMATOLOGY. 2008;58(7):1931-1939
Modulation of CCR2 in rheumatoid arthritis - A double-blind, randomized, placebo-controlled clinical trial
Vergunst CE; Gerlag DM; Lopatinskaya L; Klareskog L; Smith MD; van den Bosch F; Dinant HJ; Lee Y; Wyant T; Jacobson EW; Baeten D; Tak PP
Article: GENES AND IMMUNITY. 2008;9(5):412-418
Differential expression of transcripts for the autoimmunity-related human dendritic cell immunoreceptor
Ronninger M; Eklow C; Lorentzen JC; Klareskog L; Padyukov L
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;141(1):69-72
Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis
Baecklund E; Natkunam Y; Backlin C; Iliadou A; Askling J; Ekbom A; Feltelius N; Klareskog L; Enblad G; Lossos IS; Levy R; Sundstroem C; Rosenquist R
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(3):330-334
Treatment of refractory SLE with rituximab plus cyclophosphamide:: clinical effects, serological changes, and predictors of response
Jonsdottir T; Gunnarsson I; Risselada A; Henriksson EW; Klareskog L; van Vollenhoven RF
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;152(1):192-199
Suppressive effects of a quinoxaline-analogue (Rob 803) on pathogenic immune mechanisms in collagen-induced arthritis
Westman E; Ngoc DDT; Klareskog L; Harris HE
Article: PLOS GENETICS. 2008;4(1):e4
Analysis and application of European genetic substructure using 300 KSNP information
Tian C; Plenge RM; Ransom M; Lee A; Villoslada P; Selmi C; Klareskog L; Pulver AE; Qi L; Gregersen PK; Seldin MF
Article: ARTHRITIS & RHEUMATOLOGY. 2008;58(1):36-45
Antibodies against citrullinated vimentin in rheumatoid arthritis
Mathsson L; Mullazehi M; Wick MC; Sjoberg O; van Vollenhoven R; Klareskog L; Ronnelid J
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(12):3928-3939
Disease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritis
van der Heijde D; Klareskog L; Landewe R; Bruyn GAW; Cantagrel A; Durez P; Herrero-Beaumont G; Molad Y; Codreanu C; Valentini G; Zahora R; Pedersen R; MacPeek D; Wajdula J; Fatenejad S
Article: NATURE GENETICS. 2007;39(12):1477-1482
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis
Plenge RM; Cotsapas C; Davies L; Price AL; Bakker PIW; Maller J; Pe'er I; Burtt NP; Blumenstiel B; DeFelice M; Parkin M; Barry R; Winslow W; Healy C; Graham RR; Neale BM; Izmailova E; Roubenoff R; Parker AN; Glass R; Karlson EW; Maher N; Hafler DA; Lee DM; Seldin MF; Remmers EF; Lee AT; Padyukov L; Alfredsson L; Coblyn J; Weinblatt ME; Gabriel SB; Purcell S; Klareskog L; Gregersen PK; Shadick NA; Daly MJ; Altshuler D
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2007;36(6):418-423
Infliximab dosage and infusion frequency in clinical practice: experiences in the Stockholm biologics registry STURE
van Vollenhoven RF; Klareskog L
Article: BLOOD. 2007;110(7):2484-2493
Natural killer cells trigger differentiation of monocytes into dendritic cells
Zhang AL; Colmenero P; Purath U; de Matos CT; Hueber W; Klareskog L; Tarner IH; Engleman EG; Soderstrom K
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(10):1339-1344
Time-dependent increase in risk of hospitalisation with infection among Swedish RA patients treated with TNF antagonists
Askling J; Fored CM; Brandt L; Baecklund E; Bertilsson L; Feltelius N; Coster L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapaa-Dahlqvist S; Saxne T; van Vollenhoven RF; Klareskog L
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2007;357(12):1199-1209
TRAF1-C5 as a risk locus for rheumatoid arthritis - A genomewide study
Plenge RM; Seielstad M; Padyukov L; Lee AT; Remmers EF; Ding B; Liew A; Khalili H; Chandrasekaran A; Davies LRL; Li W; Tan AKS; Bonnard C; Ong RTH; Thalamuthu A; Pettersson S; Liu C; Tian C; Chen WV; Carulli JP; Beckman EM; Altshuler D; Alfredsson L; Criswell LA; Amos CI; Seldin MF; Kastner DL; Klareskog L; Gregersen PK
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2007;357(10):977-986
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus
Remmers EF; Plenge RM; Lee AT; Graham RR; Hom G; Behrens TW; de Bakker PIW; Le JM; Lee H-S; Batliwalla F; Li W; Masters SL; Booty MG; Carulli JP; Padyukov L; Alfredsson L; Klareskog L; Chen WV; Amos CI; Criswell LA; Seldin MF; Kastner DL; Gregersen PK
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2007;36(5):351-358
Randomized withdrawal of long-term prednisolone treatment in rheumatoid arthritis:: Effects on inflammation and bone mineral density
Tengstrand B; Larsson E; Klareskog L; Hafstroem I
Article: PLOS MEDICINE. 2007;4(9):e278-1524
A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis
Kurreeman FAS; Padyukov L; Marques RB; Schrodi SJ; Seddighzadeh M; Stoeken-Rijsbergen G; van der Helm-van Mil AHM; Allaart CF; Verduyn W; Houwing-Duistermaat J; Alfredsson L; Begovich AB; Klareskog L; Huizinga TWJ; Toes REM
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(8):2620-2632
Association of arthritis with a gene complex encoding C-type lectin-like receptors
Lorentzen JC; Flornes L; Eklow C; Backdahl L; Ribbhammar U; Guo JP; Smolnikova M; Dissen E; Seddighzadeh M; Brookes AJ; Alfredsson L; Klareskog L; Padyukov L; Fossum S
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(7):2202-2210
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis
Sigurdsson S; Padyukov L; Kurreeman FAS; Liljedahl U; Wiman A-C; Alfredsson L; Toes R; Ronnelid J; Klareskog L; Huizinga TWJ; Alm G; Syvanen A-C; Ronnblom L
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2007;80(5):867-875
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis
Kallberg H; Padyukov L; Plenge RM; Ronnelid J; Gregersen PK; van der Helm-van Mil AHM; Toes REM; Huizinga TW; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(4):481-485
Sulphasalazine inhibits human antigen-specific immune responses in vivo
Trollmo C; Gudmundsson S; Feltelius N; Rogberg S; Smedegard G; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(3):414-416
The inflammatory reflex and risk for rheumatoid arthritis: a case-control study of human vagotomy
Carlens C; Brandt L; Klareskog L; Lampa J; Askling J
Article: ARTHRITIS RESEARCH & THERAPY. 2007;9(5):r98
A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity
Olsson LM; Lindqvist A-K; Kallberg H; Padyukov L; Burkhardt H; Alfredsson L; Klareskog L; Holmdahl R
Article: CLINICAL IMMUNOLOGY. 2007;122(1):62-74
Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE
Vallerskog T; Gunnarsson I; Widhe M; Risselada A; Klareskog L; van Vollenhoven R; Malmstrom V; Trollmo C
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(12):3774-3781
Characteristics of diffuse large B cell lymphomas in rheumatoid arthritis
Baecklund E; Backlin C; Iliadou A; Granath F; Ekbom A; Amini R-M; Feltelius N; Enblad G; Sundstrom C; Klareskog L; Askling J; Rosenquist R
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(12):1578-1584
A long-term, open-label trial of the safety and efficacy of etanercept (Enbrel) in patients with rheumatoid arthritis not treated with other disease-modifying antirheumatic drugs
Klareskog L; Gaubitz M; Rodriguez-Valverde V; Malaise M; Dougados M; Wajdula J
Article: TWIN RESEARCH AND HUMAN GENETICS. 2006;9(6):875-882
The Swedish Twin Registry in the third millennium:: An update
Lichtenstein P; Sullivan PF; Cnattingius S; Gatz M; Johansson S; Carlstrom E; Bjork C; Svartengren M; Wolk A; Klareskog L; de Faire U; Schalling M; Palmgren J; Pedersen NL
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(10):3119-3125
Disconnect between inflammation and joint destruction after treatment with etanercept plus methotrexate -: Results from the trial of etanercept and methotrexate with radiographic and patient outcomes
Landewe R; van der Heijde D; Klareskog L; van Vollenhoven R; Fatenejad S
Article: PLOS GENETICS. 2006;2(9):e143-1351
European population substructure: Clustering of northern and southern populations
Seldin MF; Shigeta R; Villoslada P; Selmi C; Tuomilehto J; Silva G; Belmont JW; Klareskog L; Gregersen PK
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(9):1219-1222
Citrullination is an inflammation-dependent process
Makrygiannakis D; af Klint E; Lundberg IE; Lofberg R; Ulfgren A-K; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(9):1184-1187
Risk for malignant lymphoma in ankylosing spondylitis: a nationwide Swedish case-control study
Askling J; Klareskog L; Blomqvist P; Fored M; Feltelius N
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(8):1102-1105
Trends in disease modifying antirheumatic drug prescription in early rheumatoid arthritis are influenced more by hospital setting than patient or disease characteristics
Carli C; Ehlin AGC; Klareskog L; Lindblad S; Montgomery SM
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;63(6):444-452
FOXP3 identifies regulatory CD25^brigntCD4⁺ T cells in rheumatic joints
Cao D; Borjesson O; Larsson P; Rudin A; Gunnarsson I; Klareskog L; Malmstrom V; Trollmo C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(6):741-745
Impact of parental history on patients' cardiovascular mortality in rheumatoid arthritis
Björnådal L; Brandt L; Klareskog L; Askling J
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(5):1463-1472
Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritis
Makrygiannakis D; af Klint E; Catrina S-B; Botusan IR; Klareskog E; Klareskog L; Ulfgren A-K; Catrina AI
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(4):1063-1074
Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis - Two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial
van der Heijde D; Klareskog L; Rodriguez-Valverde V; Codreanu C; Bolosiu H; Melo-Gomes J; Tornero-Molina J; Wajdula J; Pedersen R; Fatenejad S
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(3):692-701
Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis
Baecklund E; Iliadou A; Askling J; Ekborn A; Backlin C; Granath F; Catrina AT; Rosenquist R; Feltelius N; Sundström C; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(3):328-334
Patient reported outcomes in a trial of combination therapy with etanercept and methotrexate for rheumatoid arthritis: the TEMPO trial
van der Heijde D; Klareskog L; Singh A; Tornero J; Melo-Gomes J; Codreanu C; Pedersen R; Freundlich B; Fatenejad S
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(1):R18
Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor
Ernestam S; Klint EA; Catrina AI; Sundberg E; Engström M; Klareskog L; Ulfgren K
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2006;35(1):7-14
A two-year follow-up of work capacity in early rheumatoid arthritis:: a study of multidisciplinary team care with emphasis on vocational support
Nordmark B; Blomqvist P; Andersson B; Hägerström B; Nordh-Grate K; Rönnqvist R; Svensson H; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(1):76-81
Anti-tumor necrosis factor therapy increases synovial osteoprotegerin expression in rheumatoid arthritis
Catrina AI; af Klint E; Ernestam S; Catrina SB; Makrygiannakis D; Botusan IR; Klareskog L; Ulfgren AK
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(1):38-46
A new model for an etiology of rheumatoid arthritis
Klareskog L; Stolt P; Lundberg K; Källberg H; Bengtsson C; Grunewald J; Rönnelid J; Harris HE; Ulfgren AK; Rantapää-Dahlqvist S; Eklund A; Padyukov L; Alfredsson L
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(6):R179
Effect of infliximab on mRNA expression profiles in synovial tissue of rheumatoid arthritis patients
Lindberg J; af Klint E; Catrina AI; Nilsson P; Klareskog L; Ulfgren A-K; Lundeberg J
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(2):r47
Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technology
Lindberg J; af Klint E; Ulfgren A-K; Stark A; Andersson T; Nilsson P; Klareskog L; Lundeberg J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2005;34(5):353-358
Adalimumab (Humira®) restores clinical response in patients with secondary loss of efficacy from infliximab (Remicade®) or etanercept (Enbrel®):: results from the STURE registry at Karolinska University Hospital
Wick MC; Ernestam S; Lindblad S; Bratt J; Klareskog L; van Vollenhoven RF
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2005;77(6):1044-1060
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden:: Association of susceptibility with PTPN22, CTLA4, and PADI4
Plenge RM; Padyukov L; Remmers EF; Purcell S; Lee AT; Karlson EW; Wolfe F; Kastner DL; Alfredsson L; Altshuler D; Gregersen PK; Klareskog L; Rioux JD
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(12):3880-3889
Intraarticular glucocorticoid treatment reduces inflammation in synovial cell infiltrations more efficiently than in synovial blood vessels
af Klint E; Grundtman C; Engström M; Catrina AI; Makrygiannakis D; Klareskog L; Andersson U; Ulfgren AK
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(12):1744-1749
Longitudinal analysis of citrullinated protein/peptide antibodies (anti-CP) during 5 year follow up in early rheumatoid arthritis:: anti-CP status predicts worse disease activity and greater radiological progression
Rönnelid J; Wick MC; Lampa J; Lindblad S; Nordmark B; Klareskog L; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(12):1765-1768
Do steroids increase lymphoma risk?: A case-control study of lymphoma risk in polymyalgia rheumatica/giant cell arteritis
Askling J; Klareskog L; Hjalgrim H; Baecklund E; Björkholm M; Ekbom A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(11):1582-1587
Comparison of different definitions to classify remission and sustained remission:: 1 year TEMPO results
van der Heijde D; Klareskog L; Boers M; Landewé R; Codreanu C; Bolosiu HD; Pedersen R; Fatenejad S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(11):1588-1594
Socioeconomic status and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study
Bengtsson C; Nordmark B; Klareskog L; Lundberg I; Alfredsson L
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(11):3439-3447
Effects of antirheumatic treatments on the prostaglandin E₂ Biosynthetic pathway
Korotkova M; Westman M; Gheorghe KR; af Klint E; Trollmo C; Ulfgren AK; Klareskog L; Jakobsson PJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(10):1414-1420
Haematopoietic malignancies in rheumatoid arthritis:: lymphoma risk and characteristics after exposure to tumour necrosis factor antagonists
Askling J; Fored CM; Baecklund E; Brandt L; Backlin C; Ekbom A; Sundström C; Bertilsson L; Cöster L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapää-Dahlqvist S; Saxne T; Klareskog L; Feltelius N
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(10):1421-1426
Risks of solid cancers in patients with rheumatoid arthritis and after treatment with tumour necrosis factor antagonists
Askling J; Fored CM; Brandt L; Baecklund E; Bertilsson L; Feltelus N; Cöster L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapää-Dahlqvist S; Saxne T; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(8):1174-1179
Cost effectiveness of etanercept (Enbrel) in combination with methotrexate in the treatment of active rheumatoid arthritis based on the TEMPO trial
Kobelt G; Lindgren P; Singh A; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(7):1986-1992
Risk and case characteristics of tuberculosis in rheumatoid arthritis associated with tumor necrosis factor antagonists in Sweden
Askling J; Fored CM; Brandt L; Baecklund E; Bertilsson L; Cöster L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapää-Dahlqvist S; Saxne T; Romanus V; Klareskog L; Feltelius N
Article: NATURE GENETICS. 2005;37(5):486-494
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction
Swanberg M; Lidman O; Padyukov L; Eriksson P; Åkesson E; Jagodic M; Lobell A; Khademi M; Borjesson O; Lindgren CM; Lundman P; Brookes AJ; Kere J; Luthman H; Alfredsson L; Hillert J; Klareskog L; Hamsten A; Piehl F; Olsson T
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(4):654
Feasibility of 1 hour infliximab infusions
van Vollenhoven RF; Gullström E; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(4):582-586
Silica exposure is associated with increased risk of developing rheumatoid arthritis:: results from the Swedish EIRA study
Stolt P; Källberg H; Lundberg I; Sjögren B; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(3):494-496
CNI-1493, an inhibitor of proinflammatory cytokines, retards cartilage destruction in rats with collagen induced arthritis
Larsson E; Harris HE; Palmblad K; Månsson B; Saxne T; Klareskog L
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2005;40(2):170-174
Antitissue transglutaminase and antithyroid autoantibodies in children with Down syndrome and celiac disease
Hansson T; Dahlborn T; Rogberg S; Nyberg BI; Dahlström J; Annerén G; Klareskog L; Dannaeus A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(2):246-252
Results from a nationwide postmarketing cohort study of patients in Sweden treated with etanercept
Feltelius N; Fored CM; Blomqvist P; Bertilsson L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapää-Dahlqvist S; Saxne T; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(1):61-72
Evidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints - Extended report
Catrina AI; Trollmo C; af Klint E; Engstrom M; Lampa J; Hermansson Y; Klareskog L; Ulfgren AK
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(1):49-60
Presentation and analysis of data on radiographic outcome in clinical trials -: Experience from the TEMPO study
van der Heijde D; Landewé R; Klareskog L; Rodríguez-Valverde V; Settas L; Pedersen R; Fatenejad S
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(1):192-200
Lipid peroxidation is enhanced in patients with systemic lupus erythematosus and is associated with arterial and renal disease manifestations
Frostegård J; Svenungsson E; Wu RH; Gunnarsson I; Lundberg IE; Klareskog L; Hörkko S; Witztum JL
Article: ARTHRITIS RESEARCH & THERAPY. 2005;7(3):R458-R467
Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity
Lundberg K; Nijenhuis S; Vossenaar ER; Palmblad K; van Venrooij WJ; Klareskog L; Zendman AJW; Harris HE
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(1):134-137
Estimated prediagnosis radiological progression: an important tool for studying the effects of early disease modifying antirheumatic drug treatment in rheumatoid arthritis
Wick MC; Lindblad S; Weiss RJ; Klareskog L; van Vollenhoven RF
Article: ARTHRITIS RESEARCH & THERAPY. 2005;7(6):R1296-R1303
Association between occupational exposure to mineral oil and rheumatoid arthritis:: results from the Swedish EIRA case-control study
Sverdrup B; Källberg H; Bengtsson C; Lundberg I; Padyukov L; Alfredsson L; Klareskog L
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2004;33(6):423-427
Biopsy-verified response of severe lupus nephritis to treatment with rituximab (anti-CD20 monoclonal antibody) plus cyclophosphamide after biopsy-documented failure to respond to cyclophosphamide alone
van Vollenhoven RF; Gunnarsson I; Welin-Henriksson E; Sundelin B; Österborg A; Jacobson SH; Klareskog L
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2004;33(6):380-384
Clinical and radiological disease-course in a Swedish DMARD-treated early RA-inception cohort: an observational study
Wick MC; Lindblad S; Weiss RJ; Klareskog L; van Vollenhoven RF
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(10):3085-3092
A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis
Padyukov L; Silva C; Stolt P; Alfredsson L; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(9):1075-1078
Treatment with tumour necrosis factor a antagonists in patients with rheumatoid arthritis induces anticardiolipin antibodies
Jonsdottir T; Forslid J; van Vollenhoven A; Harju A; Brannemark S; Klareskog L; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(7):848-852
Relationship between inflammation and joint destruction in early rheumatoid arthritis: a mathematical description
Wick MC; Lindblad S; Klareskog L; van Vollenhoven RF
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(6):1774-1780
Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synovium
Westman M; Korotkova M; af Klint E; Stark A; Audoly LP; Klareskog L; Ulfgren AK; Jakobsson P
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(6):1770-1773
Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope
Prokunina L; Padyukov L; Bennet A; de Faire U; Wiman B; Prince J; Alfredsson L; Klareskog L; Alarcón-Riquelme M
Article: JOURNAL OF RHEUMATOLOGY. 2004;31(4):713-719
Cardiovascular disease a hazard despite improved prognosis in patients with systemic lupus erythematosus:: Results from a Swedish population based study 1964-95
Björnådal L; Yin L; Granath F; Klareskog L; Ekbom A
Article: AMERICAN JOURNAL OF THE MEDICAL SCIENCES. 2004;327(4):196-201
The additive role of innate and adaptive immunity in the development of arthritis
Malmström V; Trollmo C; Klareskog L
Article: RHEUMATOLOGY. 2004;43(4):428-434
Corticosteroid treatment of experimental arthritis retards cartilage destruction as determined by histology and serum COMP
Larsson E; Harris HE; Larsson A; Månsson B; Saxne T; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(4):426-430
Dose escalation of infliximab in clinical practice: improvements seen may be explained by a regression-like effect
van Vollenhoven RF; Brannemark S; Klareskog L
Article: JOURNAL OF RHEUMATOLOGY. 2004;31(3):422-425
Polymorphism in promoter region of IL10 gene is associated with rheumatoid arthritis in women
Padyukov L; Hytönen AM; Smolnikova M; Hahn-Zoric M; Nilsson N; Hanson L; Tarkowski A; Klareskog L
Article: THE LANCET. 2004;363(9410):675-681
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial
Klareskog L; van der Heijde D; de Jager JP; Gough A; Kalden J; Malaise M; Mola EM; Pavelka K; Sany J; Settas L; Wajdula J; Pedersen R; Fatenejad S; Sanda M
Article: BEST PRACTICE AND RESEARCH: CLINICAL RHEUMATOLOGY. 2004;18(1):7-19
Corticosteroids - from an idea to clinical use
Lundberg IE; Grundtman C; Larsson E; Klareskog L
Article: ARTHRITIS RESEARCH & THERAPY. 2004;6(4):R335-R346
CD25^brightCD4⁺ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
Cao DJ; van Vollenhoven R; Klareskog L; Trollmo C; Malmström V
Article: ARTHRITIS RESEARCH & THERAPY. 2004;6(4):R303-R308
A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis
Berglin E; Padyukov L; Sundin U; Hallmans G; Stenlund H; van Venrooij WJ; Klareskog L; Dahlqvist SR
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(1):297-304
Oligodeoxynucleotides containing CpG motifs can induce T cell-dependent arthritis in rats
Svelander L; Harris HE; Lorentzen JC; Trollmo C; Klareskog L; Bucht A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2003;62(12):1195-1198
Treatment with infliximab (Remicade) when etanercept (Enbrel) has failed or vice versa:: data from the STURE registry showing that switching tumour necrosis factor α blockers can make sense
van Vollenhoven R; Harju A; Brannemark S; Klareskog L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;107(1):112-119
Dynamic expression of transforming growth factor-betas (TGF-beta) and their type I and type II receptors in the synovial tissue of arthritic rats
Mussener A; Funa K; Kleinau S; Klareskog L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;108(3):415-419
Amelioration of collagen II-induced arthritis in rats by the type IV phosphodiesterase inhibitor Rolipram
Nyman U; Mussener A; Larsson E; Lorentzen J; Klareskog L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;107(3):485-493
Cytokine production in synovial tissue of mice with collagen-induced arthritis (CIA)
Mussener A; Litton MJ; Lindroos E; Klareskog L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;107(3):480-484
Characteristics of synovial fluid effusion in collagen-induced arthritis (CIA) in the DA rat; A comparison of histology and antibody reactivities in an experimental chronic arthritis model and rheumatoid arthritis (RA)
Harris HE; Liljestrom M; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(9):2533-2540
Elevated triglycerides and low levels of high-density lipoprotein as markers of disease activity in association with up-regulation of the tumor necrosis factor α/tumor necrosis factor receptor system in systemic lupus erythematosus
Svenungsson E; Gunnarsson I; Fei GZ; Lundberg IE; Klareskog L; Frostegård J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2003;62(9):835-841
Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases
Stolt P; Bengtsson C; Nordmark B; Lindblad S; Lundberg I; Klareskog L; Alfredsson L
Article: JOURNAL OF RHEUMATOLOGY. 2003;30(8):1748-1755
Evidence for immunostimulatory effects of intramuscular gold in patients with rheumatoid arthritis:: Correlation with skin reactions
Ernestam S; Lampa J; Rogberg S; Rönnelid J; Klareskog L; Hafström I
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(6):1543-1550
Lymphoma subtypes in patients with rheumatoid arthritis -: Increased proportion of diffuse large B cell lymphoma
Baecklund E; Sundström C; Ekbom A; Catrina AI; Biberfeld P; Feltelius N; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(6):1500-1503
Clinical responses to tumor necrosis factor α antagonists do not show a bimodal distribution -: Data from the Stockholm tumor necrosis factor α followup registry
van Vollenhoven RF; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2003;62(6):526-529
Genetic markers for the efficacy of tumour necrosis factor blocking therapy in rheumatoid arthritis
Padyukov L; Lampa J; Heimbürger M; Ernestam S; Cederholm T; Lundkvist I; Andersson P; Hermansson Y; Harju A; Klareskog L; Bratt J
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(4):963-970
Risk of malignant lymphomas in patients with rheumatoid arthritis and in their first-degree relatives
Ekström K; Hjalgrim H; Brandt L; Baecklund E; Klareskog L; Ekbom A; Askling J
Article: LAKARTIDNINGEN. 2003;100(8):631-632
[The proposal of the National Board of Health and Welfare counteracts knowledge development within health care].
Klareskog L; Efendic S; Brismar K; Hamsten A
Article: ARTHRITIS RESEARCH & THERAPY. 2003;5(6):R347-R351
Etanercept versus etanercept plus methotrexate: a registry-based study suggesting that the combination is clinically more efficacious
van Vollenhoven RF; Ernestam S; Harju A; Bratt J; Klareskog L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2003;33(1):215-223
Isolation and functional characterization of regulatory CD25^brightCD4⁺ T cells from the target organ of patients with rheumatoid arthritis
Cao D; Malmström V; Baecher-Allan C; Hafler D; Klareskog L; Trollmo C
Article: THE LANCET. 2002;360(9349):1935-1939
Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia
Thunberg U; Tobin G; Johnson A; Söderberg O; Padyukov L; Hultdin M; Klareskog L; Enblad G; Sundström C; Roos G; Rosenquist R
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2002;56(5):530-537
Transforming growth factor-β (TGF-β) and tissue transglutaminase expression in the small intestine in children with coeliac disease
Hansson T; Ulfgren AK; Lindroos E; Dannæus A; Dahlbom I; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2002;61(10):934-936
Low levels of apoptosis and high FLIP expression in early rheumatoid arthritis synovium
Catrina AI; Ulfgren AK; Lindblad S; Grondal L; Klareskog L
Article: RHEUMATOLOGY. 2002;41(9):996-1000
Serum concentrations of cartilage oligomeric matrix protein, fibrinogen and hyaluronan distinguish inflammation and cartilage destruction in experimental arthritis in rats
Larsson E; Harris HE; Lorentzen JC; Larsson A; Månsson B; Klareskog L; Saxne T
Article: PEDIATRIC RESEARCH. 2002;51(6):700-705
Recombinant human tissue transglutaminase for diagnosis and follow-up of childhood coeliac disease
Hansson T; Dahlbom I; Rogberg S; Dannæus A; Höpfl P; Gut H; Kraaz W; Klareskog L
Article: JOURNAL OF RHEUMATOLOGY. 2002;29(5):906-912
Decreasing mortality in patients with rheumatoid arthritis:: Results from a large population based cohort in Sweden, 1964-95
Björnådal L; Baecklund E; Yin L; Granath F; Klareskog L; Ekbom A
Article: RHEUMATOLOGY. 2002;41(5):484-489
Anti-tumour necrosis factor (TNF)-α therapy (etanercept) down-regulates serum matrix metalloproteinase (MMP)-3 and MMP-1 in rheumatoid arthritis
Catrina AI; Lampa J; Ernestam S; af Klint E; Bratt J; Klareskog L; Ulfgren AK
Article: ARTHRITIS & RHEUMATOLOGY. 2002;46(4):1044-1055
Interleukin-1α expression in capillaries and major histocompatibility complex class I expression in type II muscle fibers from polymyositis and dermatomyositis patients -: Important pathogenic features independent of inflammatory cell clusters in muscle tissue
Englund P; Nennesmo I; Klareskog L; Lundberg IE
Article: JOURNAL OF RHEUMATOLOGY. 2002;29(1):21-28
Effects of gold on cytokine production in vitro;: Increase of monocyte dependent interleukin 10 production and decrease of interferon-γ levels
Lampa J; Klareskog L; Rönnelid J
Article: LUPUS. 2002;11(7):435-442
Increased T-lymphocyte apoptosis/necrosis and IL-10 producing cells in patients and their spouses in Icelandic systemic lupus erythematosus multicase families
Gröndal G; Traustadottir KH; Kristjansdottir H; Lundberg I; Klareskog L; Erlendsson K; Steinsson K
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;114(2):277-283
A vitamin D analogue (MC 1288) has immunomodulatory properties and suppresses collagen-induced arthritis (CIA) without causing hypercalcaemia
Larsson P; Mattsson L; Klareskog L; Johnsson C
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;115(1):32-41
Anti-inflammatory effects of a new tumour necrosis factor-alpha (TNF-α) inhibitor (CNI-1493) in collagen-induced arthritis (CIA) in rats
Åkerlund K; Harris HE; Tracey KJ; Wang H; Fehniger T; Klareskog L; Andersson J; Andersson U
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;122(3):477-483
Parasite-mediated down-regulation of collagen-induced arthritis (CIA) in DA rats
Mattsson L; Larsson P; Erlandsson-Harris H; Klareskog L; Harris RA
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;120(1):174-182
Down-regulation of the T cell receptor CD3ζ chain in rheumatoid arthritis (RA) and its influence on T cell responsiveness
Berg L; Rönnelid J; Klareskog L; Bucht A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;116(2):246-250
Cytokine-producing cells in peripheral blood of children with coeliac disease secrete cytokines with a type 1 profile
Hansson T; Dannæus A; Klareskog L
Article: RHEUMATOLOGY. 2001;40(10):1175-1179
A vegan diet free of gluten improves the signs and symptoms of rheumatoid arthritis:: the effects on arthritis correlate with a reduction in antibodies to food antigens
Hafström I; Ringertz B; Spångberg A; von Zweigbergk L; Brannemark S; Nylander I; Rönnelid J; Laasonen L; Klareskog L
Article: AMERICAN JOURNAL OF PATHOLOGY. 2001;159(4):1263-1273
Skeletal muscle fibers express major histocompatibility complex class II antigens independently of inflammatory infiltrates in inflammatory myopathies
Englund P; Lindroos E; Nennesmo I; Klareskog L; Lundberg IE
Article: HUMAN MOLECULAR GENETICS. 2001;10(18):1901-1906
High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis
Barton A; Eyre S; Myerscough A; Brintnell B; Ward D; Ollier WER; Lorentzen JC; Klareskog L; Silman A; John S
Article: LIFE SCIENCES. 2001;69(15):1775-1782
Binding, pharmacological and immunological profiles of the δ-selective opioid receptor antagonist HS 378
Spetea M; Harris HE; Berzetei-Gurske IP; Klareskog L; Schmidhammer H
Article: ANNALS OF THE RHEUMATIC DISEASES. 2001;60(4):372-379
Increased levels of proinflammatory cytokines and nitric oxide metabolites in neuropsychiatric lupus erythematosus
Svenungsson E; Andersson M; Brundin L; van Vollenhoven R; Khademi M; Tarkowski A; Greitz D; Dahlström M; Lundberg I; Klareskog L; Olsson T
Article: BEST PRACTICE AND RESEARCH: CLINICAL RHEUMATOLOGY. 2001;15(1):1-15
On the organization of an early arthritis clinic
Klareskog L; Nordmark B; Lindblad S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2001;60(2):133-139
Increased peripheral T cell reactivity to microbial antigens and collagen type II in rheumatoid arthritis after treatment with soluble TNFα receptors
Berg L; Lampa J; Rogberg S; van Vollenhoven R; Klareskog L
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2001;30(5):282-289
Longitudinal study of interleukin-10, tumor necrosis factor-α, anti-U1-snRNP antibody levels and disease activity in patients with mixed connective tissue disease
Hassan AB; Gunnarsson I; Karlsson G; Klareskog L; Forslid J; Lundberg IE
Article: GENOMICS. 2000;70(3):307-314
Fine mapping of the SLEB2 locus involved in susceptibility to systemic lupus erythematosus
Magnusson V; Lindqvist AKB; Castillejo-López C; Kristjánsdottir H; Steinsson K; Gröndal G; Sturfelt G; Truedsson L; Svenungsson E; Lundberg I; Gunnarsson I; Bolstad AI; Haga HJ; Jonsson R; Klareskog L; Alcocer-Varela J; Alarcón-Segovia D; Terwilliger JD; Gyllensten UB; Alarcón-Riquelme ME
Article: ARTHRITIS & RHEUMATOLOGY. 2000;43(11):2391-2396
Systemic anti-tumor necrosis factor α therapy in rheumatoid arthritis down-regulates synovial tumor necrosis factor α synthesis
Ulfgren AK; Andersson U; Engström M; Klareskog L; Maini RN; Taylor PC
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2000;18(5):565-570
Cytokine production, serum levels and disease activity in systemic lupus erythematosus
Gröndal G; Gunnarsson I; Rönnelid J; Rogberg S; Klareskog L; Lundberg I
Article: ACTA DERMATO-VENEREOLOGICA. 2000;80(3):167-170
An immunohistochemical analysis of cytokine expression in allergic and irritant contact dermatitis
Ulfgren AK; Klareskog L; Lindberg M
Article: RHEUMATOLOGY. 2000;39(8):886-893
Development of lupus-related side-effects in patients with early RA during sulphasalazine treatment -: the role of IL-10 and HLA
Gunnarsson I; Nordmark B; Bakri AH; Gröndal G; Larsson P; Forslid J; Klareskog L; Ringertz B
Article: ANNALS OF THE RHEUMATIC DISEASES. 2000;59(7):504-505
Consensus statement on the initiation and continuation of tumour necrosis factor blocking therapies in rheumatoid arthritis
Smolen JS; Breedveld FC; Burmester GR; Combe B; Emery P; Kalden JR; Klareskog L; Maini RN; Numo R; van de Putte LBA; van Riel PLCM; Rodriguez-Valverde V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2000;59(6):439-447
Interindividual and intra-articular variation of proinflammatory cytokines in patients with rheumatoid arthritis:: potential implications for treatment
Ulfgren AK; Gröndal L; Lindblad S; Khademi M; Johnell O; Klareskog L; Andersson U
Article: JOURNAL OF RHEUMATOLOGY. 2000;27(5):1171-1177
Rheumatoid arthritis in Sweden. Drug prescriptions, costs, and adverse drug reactions
Blomqvist P; Feltelius N; Ekbom A; Klareskog L
Article: JOURNAL OF AUTOIMMUNITY. 2000;14(3):267-274
Kinetics of anti-fibrillin-1 autoantibodies in MCTD and CREST syndrome
Lundberg I; Antohi S; Takeuki K; Arnett F; Steiner G; Brumeanu TD; Klareskog L; Bona C
Article: LAKARTIDNINGEN. 2000;97(17):2110-2111
[Current medicine requires cooperation--not omnipotence].
Klareskog L
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2000;30(4):379-384
Antibody reactivity against human and guinea pig tissue transglutaminase in children with celiac disease
Hansson T; Dahlbom I; Hall J; Holtz A; Elfman L; Dannaeus A; Klareskog L
Article: LAKARTIDNINGEN. 2000;97(1-2):30-33
[Future treatment of rheumatism. A compromise in the game between inflammation and infections].
Klareskog L; Lundberg I
Article: JOURNAL OF RHEUMATOLOGY. 1999;26(10):2148-2152
Genetic analysis of the contribution of IL10 to systemic lupus erythematosus
Alarcón-Riquelme ME; Lindqvist AKB; Jonasson I; Johanneson B; Sandino S; Alcocer-Varela J; Granados J; Kristjánsdóttir H; Gröndal G; Svenungsson E; Lundberg I; Steinsson K; Klareskog L; Sturfelt G; Truedsson L; Alarcon-Segovia D; Gyllensten UB
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1999;29(3):286-292
Celiac disease in relation to immunologic serum markers, trace elements, and HLA-DR and DQ antigens in Swedish children with Down syndrome
Hansson T; Annerén G; Sjöberg O; Klareskog L; Dannæus A
Article: ARTHRITIS & RHEUMATOLOGY. 1999;42(8):1649-1654
Increased number of interleukin-10-producing cells in systemic lupus erythematosus patients and their first-degree relatives and spouses in Icelandic multicase families
Gröndal G; Kristjansdottir H; Gunnlaugsdottir B; Arnason A; Lundberg I; Klareskog L; Steinsson K
Article: SURGERY. 1998;124(3):503-509
Major histocompatibility complex class II expression and parathyroid autoantibodies in primary hyperparathyroidism
Bjerneroth G; Juhlin C; Gudmundsson S; Rastad J; Åkerström G; Klareskog L
Article: THE BMJ. 1998;317(7152):180-181
Disease activity and risk of lymphoma in patients with rheumatoid arthritis:: nested case-control study
Baecklund E; Ekbom A; Sparén P; Feltelius N; Klareskog L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(11):6383-6387
Identification of rat susceptibility loci for adjuvant-oil-induced arthritis
Lorentzen JC; Glaser A; Jacobsson L; Galli J; Fakhrai-Rad H; Klareskog L; Luthman H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1998;47(3):254-262
Decreased expression of signal-transducing CD3 ζ chains in T cells from the joints and peripheral blood of rheumatoid arthritis patients
Matsuda M; Ulfgren AK; Lenkei R; Petersson M; Ochoa AC; Lindblad S; Andersson P; Klareskog L; Kiessling R
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 1998;106(1):27-32
Common commercial cosmetic products induce arthritis in the DA rat
Sverdrup B; Klareskog L; Kleinau S
Article: BRITISH JOURNAL OF RHEUMATOLOGY. 1998;37(1):7-14
Production of T-cell cytokines at the single-cell level in patients with inflammatory arthritides:: Enhanced activity in synovial fluid compared to blood
Rönnelid J; Berg L; Rogberg S; Nilsson A; Albertsson K; Klareskog L
Article: BRITISH JOURNAL OF RHEUMATOLOGY. 1997;36(12):1258-1261
Increased serum levels of cartilage oligomeric matrix protein and bone sialoprotein in rats with collagen arthritis
Larsson E; Müssener Å; Heinegård D; Klareskog L; Saxne T
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;46(6):619-624
Immunization with alum-collagen II complex suppresses the development of collagen-induced arthritis in rats by deviating the immune response
Mattsson L; Lorentzen JC; Svelander L; Bucht A; Nyman U; Klareskog L; Larsson P
Article: ARTHRITIS & RHEUMATOLOGY. 1997;40(5):865-874
Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies
Lundberg I; Ulfgren AK; Nyberg P; Andersson U; Klareskog L
Article: PEDIATRIC RESEARCH. 1997;41(4):554-559
Production of antibodies to gliadin by peripheral blood lymphocytes in children with celiac disease: The use of an enzyme-linked immunospot technique for screening and follow-up
Hansson T; Dannaeus A; Kraaz W; Sjoberg O; Klareskog L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(3):695-699
Altered Th1/Th2 balance associated with nonmajor histocompatibility complex genes in collagen-induced arthritis in resistant and nonresistant rat strains
Mussener A; Lorentzen JC; Kleinau S; Klareskog L
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 1997;200(1-2):17-26
A comparison between ELISPOT methods for the detection of cytokine producing cells: Greater sensitivity and specificity using ELISA plates as compared to nitrocellulose membranes
Ronnelid J; Klareskog L
Article: LAKARTIDNINGEN. 1997;94(1-2):24-27
[New perspectives on rheumatoid arthritis].
Klareskog L
Article: BRITISH JOURNAL OF RHEUMATOLOGY. 1997;36(1):32-37
Association between ongoing anti-Clq antibody production in peripheral blood and proliferative nephritis in patients with active systemic lupus erythematosus
Gunnarsson I; Ronnelid J; Huang YH; Rogberg S; Nilsson B; Lundberg I; Klareskog L
Article: UGESKRIFT FOR LAEGER. 1996;158(51):7379-7383
[Nobel Prize for discovery of the cell-mediated immune defence].
Klareskog L; Kärre K; Möller E; Wigzell H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(6):592-598
Susceptibility of DA rats to arthritis induced with adjuvant oil or rat collagen is determined by genes both within and outside the major histocompatibility complex
Lorentzen JC; Klareskog L
Article: SURGERY. 1996;120(6):985-992
Expression and function of a CD4-like molecule in parathyroid tissue
Hellman P; KarlssonParra A; Klareskog L; Ridefelt P; Bjerneroth G; Rastad J; Akerstrom G; Juhlin C
Article: LAKARTIDNINGEN. 1996;93(42):3714-3717
[The Nobel Prize for discovery of the cell-mediated immune defense. Significance for clinical medicine].
Klareskog L; Kärre K; Möller E; Wigzell H
Article: JOURNAL OF NEUROIMMUNOLOGY. 1995;63(2):193-205
Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant
Lorentzen JC; Issazadeh S; Storch M; Mustafa MI; Lassman H; Linington C; Klareskog L; Olsson T
Article: ANNALS OF THE RHEUMATIC DISEASES. 1995;54(8):654-661
DETECTION OF CYTOKINE PRODUCING CELLS IN THE SYNOVIAL-MEMBRANE FROM PATIENTS WITH RHEUMATOID-ARTHRITIS
ULFGREN AK; LINDBLAD S; KLARESKOG L; ANDERSSON J; ANDERSSON U
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):128-134
TNF-ALPHA DOMINATES CYTOKINE MESSENGER-RNA EXPRESSION IN LYMPHOID-TISSUES OF RATS DEVELOPING COLLAGEN-INDUCED AND OIL-INDUCED ARTHRITIS
MUSSENER A; KLARESKOG L; LORENTZEN JC; KLEINAU S
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):82-89
SPECIFIC AND LONG-LASTING PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS AND OIL-INDUCED ARTHRITIS IN DA RATS BY ADMINISTRATION OF IMMUNOGENS
LORENTZEN JC; ERLANDSSON H; MUSSENER A; MATTSSON L; KLEINAU S; NYMAN U; KLARESKOG L
Article: INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY. 1995;17(5):393-401
OIL-INDUCED ARTHRITIS IN DA RATS - TISSUE DISTRIBUTION OF ARTHRITOGENIC C-14-LABELED HEXADECANE
KLEINAU S; DENCKER L; KLARESKOG L
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All other publications

Letter: ARTHRITIS & RHEUMATOLOGY. 2024;76(4):660-661
Clinical Images: Hairy kidney in IgG4-related disease Reply
Alfredsson L; Klareskog L; Hedstrom AK
Letter: ARTHRITIS & RHEUMATOLOGY. 2024;76(3):487-488
The link among alcohol consumption, disease progression, and quality of life in rheumatoid arthritis: comment on the article by Alfredsson et al Reply
Alfredsson L; Klareskog L; Hedstroem AK
Published conference paper: SEMINARS IN ARTHRITIS AND RHEUMATISM. 2024;64:152322
Rheumatology tolerance for cure (RTCure) - an IMI project aimed at prevention and cure of RA
Klareskog L
Corrigendum: NATURE IMMUNOLOGY. 2023;24(11):1960
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets (vol 24, pg 1540, 2023)
Zhao JH; Stacey D; Eriksson N; Macdonald-Dunlop E; Hedman AK; Kalnapenkis A; Enroth S; Cozzetto D; Digby-Bell J; Marten J; Folkersen L; Herder C; Jonsson L; Bergen SE; Gieger C; Needham EJ; Hudjasov G; Surendran P; Estonian Biobank Res Team O; Paul DS; Polasek O; Thorand B; Grallert H; Roden M; Vosa U; Esko T; Hayward C; Johansson A; Gyllensten U; Powell N; Hansson O; Mattsson-Carlgren N; Joshi PK; Danesh J; Padyukov L; Klareskog L; Landen M; Wilson JF; Siegbahn A; Wallentin L; Maelarstig A; Butterworth AS; Peters JE
Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):3923
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality (vol 14, 3453, 2023)
Oddsson AR; Sulem P; Sveinbjornsson G; Arnadottir G; Steinthorsdottir VM; Halldorsson G; Atlason B; Oskarsson GO; Helgason H; Nielsen HS; Westergaard D; Karjalainen JA; Katrinardottir H; Fridriksdottir R; Jensson BB; Tragante V; Ferkingstad EA; Jonsson H; Gudjonsson S; Beyter D; Moore KHS; Thordardottir H; Kristmundsdottir S; Stefansson O; Rantapaeae-Dahlqvist S; Sonderby IE; Didriksen M; Stridh PA; Haavik J; Tryggvadottir L; Frei O; Walters GB; Kockum I; Hjalgrim H; Olafsdottir T; Selbaek G; Nyegaard M; Erikstrup C; Brodersen T; Saevarsdottir S; Olsson T; Nielsen KR; Haraldsson A; Bruun MT; Hansen TF; Steingrimsdottir TT; Jacobsen RL; Lie R; Djurovic S; Alfredsson L; Lopez de Lapuente Portilla A; Brunak SV; Melsted P; Halldorsson B; Saemundsdottir J; Magnusson OT; Padyukov L; Banasik K; Rafnar T; Askling J; Klareskog L; Pedersen OB; Masson G; Havdahl AA; Nilsson B; Andreassen O; Daly M; Ostrowski SR; Jonsdottir I; Stefansson H; Holm H; Helgason A; Thorsteinsdottir UF; Stefansson K; Gudbjartsson D
Review: IMMUNOTHERAPY ADVANCES. 2023;3(1):ltad016
Prevention vs treatment of rheumatoid arthritis
Klareskog L; Alfredsson L
Letter: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):239
Response to Comment "Sex-specific exposures and sex-combined outcomes in two-sample Mendelian randomization may mislead the causal inference" on "Age at menarche, age at natural menopause, and risk of rheumatoid arthritis-a Mendelian randomization study"
Zhu J; Niu Z; Alfredsson L; Klareskog L; Padyukov L; Jiang X
Corrigendum: NATURE REVIEWS IMMUNOLOGY. 2022;22(7):459
The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting (vol 17, pg 60, 2017)
Malmstrom V; Catrina AI; Klareskog L
Editorial comment: NATURE REVIEWS. RHEUMATOLOGY. 2022;18(1):7-8
Passive smoking in childhood accelerates RA risk for smokers
Klareskog L
Letter: ARTHRITIS & RHEUMATOLOGY. 2021;73(10):1944-1945
Untitled Reply
Tang B; Alfredsson L; Klareskog L; Padyukov L; Shi H; Jiang X
Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(3):602-620
Technological readiness and implementation of genomic-driven precision medicine for complex diseases
Franks PW; Melen E; Friedman M; Sundstrom J; Kockum I; Klareskog L; Almqvist C; Bergen SE; Czene K; Hagg S; Hall P; Johnell K; Malarstig A; Catrina A; Hagstrom H; Benson M; Smith JG; Gomez MF; Orho-Melander M; Jacobsson B; Halfvarson J; Repsilber D; Oresic M; Jern C; Melin B; Ohlsson C; Fall T; Ronnblom L; Wadelius M; Nordmark G; Johansson A; Rosenquist R; Sullivan PF
Review: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(8):1921-1933
Towards prevention of autoimmune diseases: The example of rheumatoid arthritis
Hensvold A; Klareskog L
Other: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(6):1309
Anca Catrina 1971-2021 Obituary
Klareskog L; Rethi B; Hensvold A; Wahamaa H; Jakobsson P-J
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2020;79(12):e164
How to communicate in science
Klareskog L; Catrina AI; Svensson C; Malmstrom V
Letter: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020;38(5):1029-1030
Occupational physical workload and development of anti-collagen type II antibodies in rheumatoid arthritis: results from the Swedish EIRA population-based case-control study
Zeng P; Pertsinidou E; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Review: JOURNAL OF INTERNAL MEDICINE. 2020;287(5):514-533
The importance of differences; On environment and its interactions with genes and immunity in the causation of rheumatoid arthritis
Klareskog L; Ronnelid J; Saevarsdottir S; Padyukov L; Alfredsson L
Corrigendum: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(4):880
Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype (vol 105, pg 616, 2019)
Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Editorial comment: CLINICAL THERAPEUTICS. 2019;41(7):1232-1234
Understanding and Prevention of the Evolution Toward Autoimmune Rheumatoid Arthritis: The New Challenge
Klareskog L
Editorial comment: GENOME MEDICINE. 2019;11(1):9
Translating genomic medicine to the clinic: challenges and opportunities
Zhang H; Klareskog L; Matussek A; Pfister SM; Benson M
Letter: ARTHRITIS & RHEUMATOLOGY. 2019;71(2):325-327
The specificity of monoclonal anti-citrullinated protein antibodies: comment on the article by Steen et al Reply
Malmstrom V; Steen J; Klareskog L
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(8):1238-1241
Amount of smoking, duration of smoking cessation and their interaction with silica exposure in the risk of rheumatoid arthritis among males: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study
Zeng P; Chen Z; Klareskog L; Alfredsson L; Bengtsson C; Jiang X
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(8):1236-1238
Seropositivity combined with smoking is associated with increased prevalence of periodontitis in patients with rheumatoid arthritis
Eriksson K; Nise L; Alfredsson L; Catrina AI; Askling J; Lundberg K; Klareskog L; Yucel-Lindberg T
Letter: ARTHRITIS CARE AND RESEARCH. 2018;70(8):1276
From job title to occupational lifetime exposure assessment and the use of job-exposure matrices: comment on the article by Ilar et al Reply
Ilar A; Alfredsson L; Wiebert P; Klareskog L; Bengtsson C
Review: NATURE REVIEWS. RHEUMATOLOGY. 2017;13(2):79-86
Mechanisms leading from systemic autoimmunity to joint-specific disease in rheumatoid arthritis
Catrina AI; Svensson CI; Malmstrom V; Schett G; Klareskog L
Review: NATURE REVIEWS IMMUNOLOGY. 2017;17(1):60-75
The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting
Malmstrom V; Catrina AI; Klareskog L
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(5):943-946
High sodium chloride consumption enhances the effects of smoking but does not interact with SGK1 polymorphisms in the development of ACPA-positive status in patients with RA
Jiang X; Sundstrom B; Alfredsson L; Klareskog L; Rantapaa-Dahlqvist S; Bengtsson C
Review: CURRENT OPINION IN RHEUMATOLOGY. 2016;28(2):181-188
Is rheumatoid arthritis an autoimmune disease?
Chemin K; Klareskog L; Malmstrom V
Editorial comment: RHEUMATOLOGY. 2016;55(1):1-3
Predicting and preventing the development of rheumatoid arthritis
Raza K; Klareskog L; Holers VM
Review: IMMUNOLOGICAL REVIEWS. 2016;269(1):162-174
Mechanisms involved in triggering rheumatoid arthritis
Catrina AI; Joshua V; Klareskog L; Malmstrom V
Editorial comment: NATURE REVIEWS. RHEUMATOLOGY. 2015;11(5):261-262
Lungs and citrullination
Klareskog L; Catrina AI
Editorial comment: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2015;313(16):1623-1624
The Genetics of Rheumatoid Arthritis New Insights and Implications
Felson DT; Klareskog L
Editorial comment: NATURE REVIEWS DRUG DISCOVERY. 2015;14(3):149-150
Preclinical target validation using patient-derived cells
Edwards AM; Arrowsmith CH; Bountra C; Bunnage ME; Feldmann M; Knight JC; Patel DD; Prinos P; Taylor MD; Sundstrom M
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(12):e79
Response to: 'Obesity and comorbidity are independently associated with a failure to achieve remission in patients with established rheumatoid arthritis' by Ellerby et al
Sandberg MEC; Bengtsson C; Kallberg H; Wesley A; Klareskog L; Alfredsson L; Saevarsdottir S
Review: NATURE REVIEWS. RHEUMATOLOGY. 2014;10(11):645-653
Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis
Catrina AI; Ytterberg AJ; Reynisdottir G; Malmstrom V; Klareskog L
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(7):e46
The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis? Antibodies against uncitrullinated peptides seem to occur prior to the antibodies to the corresponding citrullinated peptides
Brink M; Hansson M; Ronnelid J; Klareskog L; Dahlqvist SR
Letter: ARTHRITIS & RHEUMATOLOGY. 2014;66(6):1683-1684
Studies of preclinical rheumatoid arthritis synovial histology-a comparison of animal models: comment on the article by de Hair et al Reply
de Hair MJH; van de Sande MGH; Ramwadhdoebe TH; van der Leij C; Maas M; Hansson M; Klareskog L; Landewe R; Serre G; van Schaardenburg D; Gerlag DM; van Baarsen LGM; Tak PP
Review: CURRENT OPINION IN RHEUMATOLOGY. 2014;26(1):72-79
Adaptive immunity in rheumatoid arthritis: anticitrulline and other antibodies in the pathogenesis of rheumatoid arthritis
Klareskog L; Amara K; Malmstrom V
Review: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2014;114(1):13-17
Neutralization of AntiCitrullinated Protein Antibodies in Rheumatoid Arthritis - A Way to Go?
Cerqueira CF; Klareskog L; Jakobsson P-J
Letter: NATURE GENETICS. 2013;45(5):468-469
Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge
Plenge RM; Greenberg JD; Mangravite LM; Derry JMJ; Stahl EA; Coenen MJH; Barton A; Padyukov L; Klareskog L; Gregersen PK; Mariette X; Moreland LW; Bridges SLJ; de Vries N; Huizinga TWJ; Guchelaar H-J; Friend SH; Stolovitzky G
Review: ADVANCES IN IMMUNOLOGY. 2013;118:129-158
Autoimmunity in Rheumatoid Arthritis: Citrulline Immunity and Beyond
Klareskog L; Lundberg K; Malmstrom V
Review: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(5):638-641
EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis
Gerlag DM; Raza K; van Baarsen LGM; Brouwer E; Buckley CD; Burmester GR; Gabay C; Catrina AI; Cope AP; Cornelis F; Dahlqvist SR; Emery P; Eyre S; Finckh A; Gay S; Hazes JM; van der Helm-van Mil A; Huizinga TWJ; Klareskog L; Kvien TK; Lewis C; Machold KP; Ronnelid J; van Schaardenburg D; Schett G; Smolen JS; Thomas S; Worthington J; Tak PP
Review: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(10):1713-1718
Biomarkers and personalised medicine in rheumatoid arthritis: a proposal for interactions between academia, industry and regulatory bodies
Miossec P; Verweij CL; Klareskog L; Pitzalis C; Barton A; Lekkerkerker F; Reiter S; Laslop A; Breedveld F; Abadie E; Flamion B; Dere W; Mpofu S; Goel N; Ethgen D; Mitlak B; Ormarsdottir S; Rao R; Tsouderos Y; Reginster J-Y
Review: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(8):1357-1362
Animal models for arthritis: innovative tools for prevention and treatment
Kollias G; Papadaki P; Apparailly F; Vervoordeldonk MJ; Holmdahl R; Baumans V; Desaintes C; Di Santo J; Distler J; Garside P; Hegen M; Huizinga TWJ; Juengel A; Klareskog L; McInnes I; Ragoussis I; Schett G; 't Hart B; Tak PP; Toes R; van den Berg W; Wurst W; Gay S
Editorial comment: NATURE MEDICINE. 2011;17(7):790-791
Pulling the plug on atherosclerosis Cooling down the inflammasome
Hansson GK; Klareskog L
Letter: LEUKEMIA AND LYMPHOMA. 2011;52(6):1146-1149
LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma
Baecklund E; Backlin C; Mansouri M; Klareskog L; Askling J; Iliadou AN; Enblad G; Lossos IS; Natkunam Y; Rosenquist R
Review: SEMINARS IN IMMUNOLOGY. 2011;23(2):92-98
Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis
Klareskog L; Malmstrom V; Lundberg K; Padyukov L; Alfredsson L
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A66
A MULTIPLEX MICROARRAY FOR THE DETECTION OF RHEUMATOID ARTHRITIS-ASSOCIATED AUTOANTIBODIES
Mathsson L; Hansson M; Israelsson L; Harwanegg C; Nystrand M; Klareskog L; Ronnelid J
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A21
META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IN CELIAC DISEASE AND RHEUMATOID ARTHRITIS IDENTIFIES FOURTEEN NON-HLA SHARED LOCI
Zhernakova A; Stahl EA; Trynka G; Raychaudhuri S; Festen E; Franke L; Fehrmann RSN; Kurreeman FAS; Thomson B; Gupta N; Romanos J; McManus R; Ryan AW; Turner G; Remmers EF; Greco L; Toes R; Grandone E; Mazzilli MC; Rybak A; Cukrowska B; Li Y; de Bakker PIW; Gregersen PK; Worthington J; Siminovitch KA; Klareskog L; Huizinga TWJ; Wijmenga C; Plenge RM
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A16
HLA-DRB1*04 IS A NOVEL FETAL SUSCEPTIBILITY ALLELE IN CONGENITAL HEART BLOCK
Ostberg T; Gorgen S; Salomonsson S; Ding B; Eliasson H; Elfving A; Malarstig A; Alfredsson L; Klareskog L; Hamsten A; Olsson T; Padukov L; Axelsson T; Gadler F; Jonzon A; Sonesson SE; Kockum I; Wahren-Herlenius M
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A3
HUMORAL IMMUNE RESPONSE AGAINST FIBRINOGEN EPITOPES CITRULLINATED IN VIVO IN RHEUMATOID ARTHRITIS SYNOVIAL TISSUE DETECTED BY AUTOANTIBODY MULTIPLEXING
Ronnelid J; Ossipova E; Mathsson L; Catrina A; Matsson P; Israelsson L; Malmstrom V; Klareskog L; Jakobsson P-J
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A67
VACCINATION OF PATIENTS WITH PRIMARY SJOGREN'S SYNDROME REVEALS HYPERREACTIVE B CELL COMPARTMENT WITH A SKEWED MATURATION PATTERN
Brauner S; Kvarnstom M; Gorgen S; Franzen-Malmros M; Brokstad KA; Folkersen L; Trollmo C; Klareskog L; Jonsson R; Malmstrom V; Wahren-Herlenius M
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:a20-A21
NON-HLA-DRB1 RA-ASSOCIATED RISK ALLELES ASSOCIATE WITH ANTI-CCP AND SPECIFIC ACPA LEVELS
Snir O; Gomez-Cabrero D; Klich KU; Seddighzadeh M; Catrina AI; Tegner J; Klareskog L; Padyukov L; Malmstrom V
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:a13
LUNG CHANGES ARE PRESENT IN ACPA POSITIVE RA PATIENTS ALREADY AT DISEASE ONSET
Reynsdottir G; Harju A; Engstrom M; Nyren S; Nyren S; Skold M; Eklund A; Grunewald J; Klareskog L; Catrina AI
Review: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(12):2062-2066
Prevention of autoimmune rheumatic disease: state of the art and future perspectives
Klareskog L; Gregersen PK; Huizinga TWJ
Letter: ARTHRITIS & RHEUMATOLOGY. 2010;62(11):3516-3517
Are antibodies to citrullinated antigens enriched in synovial fluids of patients with rheumatoid arthritis?: comment on the article by Snir et al Reply
Snir O; Klareskog L; Malmstrom V
Letter: NATURE GENETICS. 2010;42(10):816
Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis Reply
Lundberg K; Alfredsson L; Kallberg H; Mahdi H; Fisher BA; Malmstrom V; Venables PJ; Klareskog L
Letter: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2010;39(4):344-346
Non-participation in EIRA: a population-based case-control study of rheumatoid arthritis
Bengtsson C; Berglund A; Serra M-L; Nise L; Nordmark B; Klareskog L; Alfredsson L
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2010;69:a73
IDENTIFICATION AND FUNCTION OF T CELLS REACTIVE WITH CITRULLINATED VIMENTIN IN HLA-DRB1*0401 HUMANISED MICE AND RHEUMATOID ARTHRITIS PATIENTS
Snir O; Rieck M; Klich K; Klareskog L; Buckner JH; Malmstrom V
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2010;69:a4-A5
IDENTIFICATION OF SPECIFIC CITRULLINATION SITES ON FIBRINOGEN IN RA
Ossipova E; Malmstrom V; Catrina AI; Klareskog L; Zubarev R; Jakobsson P-J
Review: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(8):1240-1246
European biologicals registers: methodology, selected results and perspectives
Zink A; Askling J; Dixon WG; Klareskog L; Silman AJ; Symmons DPM
Editorial comment: JOURNAL OF MOLECULAR MEDICINE. 2009;87(4):357-362
On the origins of complex immune-mediated disease: the example of rheumatoid arthritis
Klareskog L; Wedren S; Alfredsson L
Review: THE LANCET. 2009;373(9664):659-672
Rheumatoid arthritis
Klareskog L; Catrina AI; Paget S
Letter: PSYCHOTHERAPY AND PSYCHOSOMATICS. 2009;78(3):193-194
Psychosocial Stress at Work and the Risk of Developing Rheumatoid Arthritis: Results from the Swedish EIRA Study
Bengtsson C; Theorell T; Klareskog L; Alfredsson L
Letter: ARTHRITIS & RHEUMATOLOGY. 2008;59(11):1685
Effects of disease-modifying antirheumatic drug treatment on the expression of RANKL and osteoprotegerin in synovial tissue: comment on the article by Haynes et al
Catrina AI; Klareskog L
Editorial comment: ARTHRITIS & RHEUMATOLOGY. 2008;58(9):2591-2597
Genome-wide single-nucleotide polymorphism studies in rheumatology: Hype or hope?
Mil AHMVDH-V; Padyukov L; Toes RM; Klareskog L; Huizinga TWJ
Review: CURRENT OPINION IN RHEUMATOLOGY. 2008;20(3):300-305
Antibodies to citrullinated proteins in arthritis:: pathology and promise
Klareskog L; Widhe M; Hermansson M; Ronnelid J
Review: ANNUAL REVIEW OF IMMUNOLOGY. 2008;26:651-675
Immunity to citrullinated proteins in rheumatoid arthritis
Klareskog L; Roennelid J; Lundberg K; Padyukov L; Adfredsson L
Review: PHARMACOLOGY AND THERAPEUTICS. 2008;117(2):244-279
Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
Tracey D; Klareskog L; Sasso EH; Salfeld JG; Tak PP
Editorial comment: ARTHRITIS & RHEUMATOLOGY. 2008;58(1):2-4
Antiinflammatory therapy for rheumatoid arthritis?
Cohen IR; Klareskog L
Letter: ARTHRITIS & RHEUMATOLOGY. 2007;56(3):1031-1032
Reply to letter by Yazici and Yazici commenting on the two-year report on the Trial of Etanercept and Methotrexate with Radiographic and Patient Outcomes
van der Heijde D; Klareskog L
Review: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(2):143-150
Consensus statement on the use of rituximab in patients with rheumatoid arthritis
Smolen JS; Keystone EC; Emery P; Breedveld FC; Betteridge N; Burmester GR; Dougados M; Ferraccioli G; Jaeger U; Klareskog L; Kvien TK; Martin-Mola E; Pavelka K
Review: CURRENT OPINION IN RHEUMATOLOGY. 2007;19(1):49-54
Smoking as a trigger for inflammatory rheumatic diseases
Klareskog L; Padyukov L; Alfredsson L
Review: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(1):34-45
EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
Combe B; Landewe R; Lukas C; Bolosiu HD; Breedveld F; Dougados M; Emery P; Ferraccioli G; Hazes JMW; Klareskog L; Machold K; Martin-Mola E; Nielsen H; Silman A; Smolen J; Yazici H
Review: CURRENT OPINION IN IMMUNOLOGY. 2006;18(6):650-655
Genes, environment and immunity in the development of rheumatoid arthritis
Klareskog L; Padyukov L; Ronnelid J; Alfredsson L
Review: NATURE CLINICAL PRACTICE RHEUMATOLOGY. 2006;2(8):425-433
Mechanisms of disease: genetic susceptibility and environmental triggers in the development of rheumatoid arthritis
Klareskog L; Padyukov L; Lorentzen J; Alfredsson L
Review: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(6):707-712
Swedish registers to examine drug safety and clinical issues in RA
Askling J; Fored CM; Geborek P; Jacobsson LTH; van Vollenhoven R; Feltelius N; Lindblad S; Klareskog L
Meeting abstract: CLINICAL IMMUNOLOGY. 2006;119:S63
Increased Baff levels after rituximab-induced B-cell depletion in SLE patients.
Wallerskog T; Zhou W; Wohren-Herlenius M; Klareskog L; Malmstrom V; Trollmo C
Letter: ARTHRITIS & RHEUMATOLOGY. 2005;52(11):3676-3678
The interaction of smoking and the HLA-DRB1 shared epitope in rheumatoid factor-positive rheumatoid arthritis:: comment on the article by Padyukov et al -: Reply
Padyukov L; Alfredsson L; Källberg H; Bengtsson C; Klareskog L
Published conference paper: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(Suppl 4):2-14
Updated consensus statement on biological agents, specifically tumour necrosis factor α (TNFα) blocking agents and interleukin-1 receptor antagonist (IL-1ra), for the treatment of rheumatic diseases, 2005
Furst DE; Breedveld FC; Kalden JR; Smolen JS; Burmester GR; Bijlsma JWJ; Dougados M; Emery P; Keystone EC; Klareskog L; Mease PJ
Editorial comment: ARTHRITIS & RHEUMATOLOGY. 2005;52(4):991-994
The treatment of rheumatoid arthritis: Getting better all the time?
van Vollenhoven RF; Klareskog L
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2005;6(1):65-66
Lipid-peroxidation is enhanced in sle patients and associated with arterial and renal disease manifestations
Frostegard J; Svenungsson E; Wu R; Gunnarsson I; Lundberg I; Klareskog L; Hörkkö S; Witztum J
Review: ARTHRITIS RESEARCH & THERAPY. 2005;7(Suppl 2):S15-S20
Modulating co-stimulation:: a rational strategy in the treatment of rheumatoid arthritis?
Malmström V; Trollmo C; Klareskog L
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:S43
Patterns of gene expression in rheumatoid arthritis synovial tissue: inter-patient variability greater then intra-patient variability in a small study
Lindberg J; af Klint E; Stark A; Andersson T; Nilsson P; Klareskog L; Ulfgren A; Lundeberg J
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:S34
Effects of anti-rheumatic treatments on the prostaglandin E₂ biosynthetic pathway in synovial tissue and synovial fluid cells from patients with rheumatoid arthritis
Korotkova M; Westman M; Gheorghe KR; af Klint E; Trollmo C; Ulfgren A-K; Klareskog L; Jakobsson P-J
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:S31-S32
Distinct patterns of RANKL/osteoprotegerin system modulation through anti-tumour necrosis factor and corticosteroid therapy in rheumatoid arthritis synovium
Catrina AI; Makrygiannakis D; af Klint E; Catrina SB; Ernestam S; Klareskog L; Ulfgren AK
Published conference paper: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(Suppl 2):ii28-ii31
What precedes development of rheumatoid arthritis?
Klareskog L; Alredsson L; Rantapää-Dahlqvist S; Berglin E; Stolt P; Padyukov L
Published conference paper: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(Suppl 2):2-12
Updated consensus statement on biological agents, specifically tumour necrosis factor α (TNFα) blocking agents and interleukin-1 receptor antagonist (IL-1ra), for the treatment of rheumatic diseases, 2004
Furst DE; Breedveld FC; Kalden JR; Smolen JS; Burmester GR; Bijlsma JWJ; Dougados M; Emery P; Keystone EC; Klareskog L; Mease PJ
Editorial comment: THE LANCET. 2004;363(9426):2011-2012
Statins in rheumatoid arthritis - two birds with one stone?
Klareskog L; Hamsten A
Review: CURRENT OPINION IN RHEUMATOLOGY. 2004;16(3):254-261
Rheumatoid arthritis and malignant lymphomas
Baecklund E; Askling J; Rosenquist R; Ekbom A; Klareskog L
Letter: THE LANCET. 2004;363(9422):1733
Etanercept and methotrexate in rheumatoid arthritis - Authors' reply
Klareskog L
Editorial comment: BEST PRACTICE AND RESEARCH: CLINICAL RHEUMATOLOGY. 2004;18(1):1-5
How is clinical progress achieved?
Klareskog L; Lindblad S
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S32-S33
Effects of anti-rheumatic treatments on expression of microsomal prostaglandin E synthase-1 in rheumatoid arthritis synovium
Korotkova M; Westman M; af Klint E; Ulfgren AK; Klareskog L; Jakobsson PJ
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S30-S31
Prediagnosis radiological progression in rheumatoid arthritis: a novel tool to study the effects of early DMARD therapy
Wick MC; Weiss RJ; Klareskog L; van Vollenhoven RF
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S10
Intra-articular steroid treatment reduces synovial HMGB1 but not IL-1 expression in chronic arthritis
Grundtman C; Klint EA; Andersson U; Klareskog L; Ulfgren A
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S18
Differential gene expression and protein expression levels of MMP and TIMP molecules in response to glucocorticoid treatment in arthritic patients
Andersson T; af Klint E; Strobel S; Andersson U; Stark A; Gelinas R; Lundeberg J; Klareskog L; Ulfgren AK
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S14-S15
CD25brightCD4⁺ regulatory T cells accumulate in inflamed joints of patients with chronic rheumatic disease
Cao D; van Vollenhoven R; Klareskog L; Trollmo C; Malmström V
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S9
Anti-tumour necrosis factor therapy modulates the OPG/OPGL system in rheumatoid arthritis synovium
Catrina AI; Ernestam S; Klint EA; Klareskog L; Ulfgren AK
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S7
Citrullinated proteins in arthritis: presence in joints and effects on immunogenicity
Lundberg K; Nijenhuis S; Vossenaar E; Klareskog L; van Venrooij WJ; Harris HE
Published conference paper: ANNALS OF THE RHEUMATIC DISEASES. 2003;61(Suppl 2):2-7
Updated consensus statement on biological agents for the treatment of rheumatoid arthritis and other rheumatic diseases (May 2002)
Furst DE; Breedveld FC; Kalden JR; Smolen JS; Antoni CE; Bijlsma JWJ; Burmester GR; Cronstein B; Keystone EC; Kavanaugh A; Klareskog L
Review: ANNALS OF THE RHEUMATIC DISEASES. 2002;62(Suppl 2):2-9
Updated consensus statement on biological agents for the treatment of rheumatoid arthritis and other immune mediated inflammatory diseases (May 2003)
Furst DE; Breedveld FC; Kalden JR; Smolen JS; Burmester GR; Dougados M; Emery P; Gibofsky A; Kavenaugh AF; Keystone EC; Klareskog L; Russell AS; van de Putte LBA; Weisman MH
Review: ARTHRITIS RESEARCH & THERAPY. 2002;4(Suppl 3):S31-S36
Genes and environment in arthritis: can RA be prevented?
Klareskog L; Lorentzen J; Padyukov L; Alfredsson L
Review: LAKARTIDNINGEN. 2001;98(8):828-831
[Blockade of TNFalpha--new therapeutic principle in severe rheumatoid arthritis].
Larsson P; Bratt J; Harju A; van Vollenhoven R; Klareskog L
Review: LAKARTIDNINGEN. 2000;97(48):5628-5632
[New drugs against rheumatoid arthritis. Improved treatment options place new demands on health care organization].
Klareskog L; Hafström I; Saxne T; Hedin PJ
Review: ANNALS OF THE RHEUMATIC DISEASES. 2000;59(7):506-510
Synovial biopsy in arthritis research: five years of concerted European collaboration
Bresnihan B; Tak PP; Emery P; Klareskog L; Breedveld F
Review: ARTHRITIS RESEARCH & THERAPY. 2000;2(1):75-84
Interferon-γ production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1*0401 and HLA-DQ8
Berg L; Rönnelid J; Sanjeevi CB; Lampa J; Klareskog L
Review: CURRENT OPINION IN IMMUNOLOGY. 1999;11(6):657-662
Rheumatoid arthritis and its animal models:: the role of TNF-α and the possible absence of specific immune reactions
Klareskog L; McDevitt H
Published conference paper: JOURNAL OF AUTOIMMUNITY. 1999;13(1):137-141
A comparison of genome-scans performed in multicase families with systemic lupus erythematosus from different population groups
Johanneson N; Steinsson K; Lindqvist AK; Kristjánsdóttir H; Gröndal G; Sandino S; Tjernström F; Sturfelt G; Granados-Arriola J; Alcocer-Varela J; Lundberg I; Jonasson I; Truedsson L; Svenungssons E; Klareskog L; Alarcón-Segovia D; Gyllensten UB; Alarcón-Riquelme ME
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1999;31(3):1594-1596
Susceptibility of rats to homologous collagen-induced arthritis depends on MHC genes in the class II region
Mattsson L; Klareskog L; Lorentzen JC
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1997;29(3):1692-1693
Comparative susceptibility of DA, LEW, and LEW.1AV1 rats to arthritis induced with different arthritogens: Mineral oil, mycobacteria, muramyl dipeptide, avridine and rat collagen type II
Lorentzen JC; Klareskog L
Published conference paper: SURGERY. 1995;118(6):1055-1062
EXPRESSION AND FUNCTION OF A CD3-LIKE MOLECULE ON NORMAL AND ABNORMAL HUMAN PARATHYROID CELLS
HELLMAN P; JUHLIN C; KARLSSONPARRA A; KLARESKOG L; RIDEFELT P; RASTAD J; AKERSTROM G
Review: JOURNAL OF INTERNAL MEDICINE. 1995;238(3):191-206
IMMUNOPATHOGENESIS AND IMMUNOTHERAPY IN RHEUMATOID-ARTHRITIS - AN AREA IN TRANSITION
KLARESKOG L; RONNELID J; HOLM G
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1995;756:225-226
RESTRICTED T-CELL RECEPTOR USAGE IN DA RATS DURING EARLY COLLAGEN-INDUCED ARTHRITIS
ERLANDSSON H; MUSSENER A; KLARESKOG L; GOLD DP
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1995;27(2):1532-1534
SUSCEPTIBILITY TO OIL-INDUCED ARTHRITIS IN THE DA RAT IS DETERMINED BY MHC AND NON-MHC GENES
LORENTZEN JC; OLSSON T; KLARESKOG L
Other: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 1995;:111-112
SYNOVIAL LINING CELL MACROPHAGES - ROLE IN LOCALIZATION AND EXPRESSION OF INFLAMMATION - DISCUSSION
HACK CE; BURMESTER GR; MAINI RN; PETER HH; FELTKAMP TEW; VANLENT P; SCHUMACHER HR; JASIN HE; KINNE R; ZVAIFLER NJ; GLANT TT; VANDENBERG WB; KLARESKOG L; HALLMAN R
Other: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 1995;:187-188
SPECIFIC IMMUNITY - ROLE IN CHRONIC ARTHRITIS AND MODELS, INCLUDING RHEUMATOID-FACTOR, EXCLUDING CARTILAGE ANTIGENS - DISCUSSION
AARDEN L; BLAKE D; ZVAIFLER NJ; VANEDEN W; MAINI RN; KLARESKOG L; MELCHERS I; GLANT TT; FELTKAMP TEW; EMMRICH F; EIBEL H; BREEDVELD FC; VEYS EM; HERMANN E; TOIVANEN; VERWEIJ; VANDEPUTTE LBA; KINNE R
Other: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 1995;:63
CARTILAGE - DISCUSSION
GLANT TT; VANDENBERG WB; ZVAIFLER NJ; EMMRICH F; MAINI RN; MELCHERS I; BURMESTER GR; KLARESKOG L; BREEDVELD FC; KINNE R; JASIN HE; HERMANN E; BLAKE D
Published conference paper: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, SUPPLEMENT. 1995;101:57-61
LOCAL VERSUS SYSTEMIC IMMUNOREACTIVITY TO COLLAGEN AND THE COLLAGE-LIKE REGION OF C1Q IN RHEUMATOID-ARTHRITIS AND SLE
RONNELID J; KLARESKOG L
Published conference paper: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, SUPPLEMENT. 1995;101:179-181
ROLE OF ADJUVANTS IN TURNING AUTOIMMUNITY INTO AUTOIMMUNE-DISEASE
KLEINAU S; LORENTZEN J; KLARESKOG L
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Professor, Senior, Department of Medicine, Karolinska Institutet, 2025-2025
Professor, Department of Medicine, Karolinska Institutet, 2020-2024

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