Lars Klareskog

About me
Publications
Public outreach and news

About me

Senior Professor of Rheumatology.

Articles

Article: RHEUMATOLOGY. 2024;63(5):1221-1229

Genome-wide investigation of persistence with methotrexate treatment in early rheumatoid arthritis

Sysojev AO; Saevarsdottir S; Diaz-Gallo L-M; Silberberg GN; Alfredsson L; Klareskog L; Baecklund E; Bjorkman L; Kastbom A; Rantapaa-Dahlqvist S; Turesson C; Jonsdottir I; Stefansson K; Frisell T; Padyukov L; Askling J; Westerlind H
Article: MICROBIOLOGY SPECTRUM. 2024;12(4):e0298123-e02923

The serological immunogenicity of the third and fourth doses of COVID-19 vaccine in patients with inflammatory rheumatic diseases on different biologic or targeted DMARDs: a Swedish nationwide study (COVID-19-REUMA)

Frodlund M; Nived P; Chatzidionysiou K; Soedergren A; Klingberg E; Hansson M; Ohlsson S; Pin E; Bengtsson A; Klareskog L; Kapetanovic M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2024;83(3):277-287

In early rheumatoid arthritis, anticitrullinated peptide antibodies associate with low number of affected joints and rheumatoid factor associates with systemic inflammation

Pertsinidou E; Saevarsdottir S; Manivel VA; Klareskog L; Alfredsson L; Mathsson-Alm L; Hansson M; Cornillet M; Serre G; Holmdahl R; Skriner K; Jakobsson P-J; Westerlind H; Askling J; Roennelid J
Article: SEMINARS IN ARTHRITIS AND RHEUMATISM. 2024;64S:152322

Rheumatology tolerance for cure (RTCure) - an IMI project aimed at prevention and cure of RA.

Klareskog L; RTCure investigators
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(3):e2315354120

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents Infection of Omicron lineages

Marcotte H; Cao Y; Zuo F; Simonelli L; Sammartino JC; Pedotti M; Sun R; Cassaniti I; Hagbom M; Piralla A; Yang J; Du L; Percivalle E; Bertoglio F; Schubert M; Abolhassani H; Sherina N; Guerra C; Borte S; Rezaei N; Kumagai-Braesch M; Xue Y; Su C; Yan Q; He P; Groenwall C; Klareskog L; Calzolai L; Cavalli A; Wang Q; Robbiani DF; Hust M; Shi Z; Feng L; Svensson L; Chen L; Bao L; Baldanti F; Xiao J; Qin C; Hammarstrom L; Yang X; Varani L; Xie XS; Pan-Hammarstrom Q
Article: RHEUMATOLOGY. 2024;:keae007

Identification of circulating autoantibodies to non-modified proteins associated with ACPA status in early rheumatoid arthritis

Lourido L; Joshua V; Hansson M; Sjoberg R; Pin E; Ruiz-Romero C; Nilsson P; Alfredsson L; Klareskog L; Blanco FJ
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(11):1910-1922

Rheumatoid Arthritis-Specific Autoimmunity in the Lung Before and at the Onset of Disease

Joshua V; Loberg Haarhaus M; Hensvold A; Wahamaa H; Gerstner C; Hansson M; Israelsson L; Stalesen R; Skoeld M; Grunewald J; Klareskog L; Groenwall C; Rethi B; Catrina A; Malmstrom V
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(11):105320

Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients

Sahlstrom P; Joshua V; Valkovskaia V; Biese C; Stalesen R; Israelsson L; Vegvari A; Scheel-Toellner D; Klareskog L; Hansson M; Hensvold A; Malmstrom V; Gronwall C
Article: RHEUMATOLOGY. 2023;62(10):3280-3290

Using human genetics to understand the epidemiological association between obesity, serum urate, and gout

Zhang L; Zhang W; Xiao C; Wu X; Cui H; Yan P; Yang C; Tang M; Wang Y; Chen L; Liu Y; Zou Y; Alfredsson L; Klareskog L; Yang Y; Yao Y; Li J; Liu Z; Yang C; Jiang X; Zhang B
Article: BRAIN BEHAVIOR AND IMMUNITY. 2023;113:212-227

Insights into FcγR involvement in pain-like behavior induced by an RA-derived anti-modified protein autoantibody

Jurczak A; Sandor K; Farinotti AB; Krock E; Hunt MA; Agalave NM; Barbier J; Simon N; Wang Z; Rudjito R; Vazquez-Mora JA; Martinez-Martinez A; Raoof R; Eijkelkamp N; Gronwall C; Klareskog L; Jimenez-Andrade JM; Marchand F; Svensson CI
Article: NATURE IMMUNOLOGY. 2023;24(9):1540-1551

Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

Zhao JH; Stacey D; Eriksson N; Macdonald-Dunlop E; Hedman AK; Kalnapenkis A; Enroth S; Cozzetto D; Digby-Bell J; Marten J; Folkersen L; Herder C; Jonsson L; Bergen SE; Gieger C; Needham EJ; Surendran P; Metspalu A; Milani L; Magi R; Nelis M; Hudjasov G; Paul DS; Polasek O; Thorand B; Grallert H; Roden M; Vosa U; Esko T; Hayward C; Johansson A; Gyllensten U; Powell N; Hansson O; Mattsson-Carlgren N; Joshi PK; Danesh J; Padyukov L; Klareskog L; Landen M; Wilson JF; Siegbahn A; Wallentin L; Malarstig A; Butterworth AS; Peters JE
Article: HUMAN GENOMICS. 2023;17(1):81

A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis

Jiang Y; Liu Q; Alfredsson L; Klareskog L; Kockum I; Jiang X
Article: SCIENTIFIC REPORTS. 2023;13(1):10058

Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs

Hedman AK; Winter E; Yoosuf N; Benita Y; Berg L; Brynedal B; Folkersen L; Klareskog L; Maciejewski M; Sirota-Madi A; Spector Y; Ziemek D; Padyukov L; Shen-Orr SS; Jelinsky SA
Article: NATURE COMMUNICATIONS. 2023;14(1):3453

Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

Oddsson A; Sulem P; Sveinbjornsson G; Arnadottir GM; Steinthorsdottir V; Halldorsson G; Atlason BO; Oskarsson G; Helgason H; Nielsen HS; Westergaard DA; Karjalainen J; Katrinardottir H; Fridriksdottir RB; Jensson B; Tragante VA; Ferkingstad E; Jonsson H; Gudjonsson S; Beyter D; Moore KHS; Thordardottir H; Kristmundsdottir S; Stefansson O; Rantapaa-Dahlqvist S; Sonderby IE; Didriksen MA; Stridh P; Haavik J; Tryggvadottir L; Frei O; Walters GB; Kockum I; Hjalgrim H; Olafsdottir T; Selbaek G; Nyegaard M; Erikstrup C; Brodersen T; Saevarsdottir S; Olsson T; Nielsen KR; Haraldsson A; Bruun MT; Hansen TF; Steingrimsdottir T; Jacobsen RLT; Lie R; Djurovic S; Alfredsson L; Lopez de Lapuente Portilla A; Brunak S; Melsted PV; Halldorsson B; Saemundsdottir J; Magnusson OT; Padyukov L; Banasik K; Rafnar T; Askling J; Klareskog L; Pedersen OB; Masson G; Havdahl A; Nilsson BA; Andreassen O; Daly M; Ostrowski SR; Jonsdottir I; Stefansson H; Holm H; Helgason A; Thorsteinsdottir U; Stefansson KF; Gudbjartsson D
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(6):872-878

Disease Activity and Health-Related Quality of Life Among Patients With Rheumatoid Arthritis With Different Alcohol Consumption Habits

Alfredsson L; Klareskog L; Hedstrom AK
Article: VACCINE. 2023;41(20):3247-3257

The impact of immunomodulating treatment on the immunogenicity of COVID-19 vaccines in patients with immune-mediated inflammatory rheumatic diseases compared to healthy controls. A Swedish nationwide study (COVID19-REUMA)

Frodlund M; Nived P; Chatzidionysiou A; Sodergren A; Klingberg E; Bengtsson A; Hansson M; Olsson S; Pin E; Klareskog L; Kapetanovic MC
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(5):673-684

Diversity and Clonality of T Cell Receptor Repertoire and Antigen Specificities in Small Joints of Early Rheumatoid Arthritis

Turcinov S; af Klint E; Van Schoubroeck B; Kouwenhoven A; Mia S; Chemin K; Wils H; Van Hove C; De Bondt A; Keustermans K; Van Houdt J; Reumers J; Felix N; Rao NL; Peeters P; Stevenaert F; Klareskog L; McKinnon M; Baker D; Suri A; Malmstroem V
Article: JOURNAL OF AUTOIMMUNITY. 2023;136:103022

The human bone marrow plasma cell compartment in rheumatoid arthritis-Clonal relationships and anti-citrulline autoantibody producing cells

Hensvold A; Horuluoglu B; Sahlstrom P; Thyagarajan R; Boada JSD; Hansson M; Mathsson-Alm L; Gerstner C; Sippl N; Israelsson L; Wedin R; Steen J; Klareskog L; Rethi B; Catrina AI; Diaz-Gallo L-M; Malmstrom V; Gronwall C
Article: BIOMOLECULES. 2023;13(4):630

Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation

Circiumaru A; Afonso MG; Wahamaa H; Krishnamurthy A; Hansson M; Mathsson-Alm L; Keszei M; Stalesen R; Ottosson L; de Vries C; Shelef MA; Malmstrom V; Klareskog L; Catrina AI; Gronwall C; Hensvold A; Rethi B
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(3):316-323

Occupational inhalable agents constitute major risk factors for rheumatoid arthritis, particularly in the context of genetic predisposition and smoking

Tang B; Liu Q; Ilar A; Wiebert P; Hagg S; Padyukov L; Klareskog L; Alfredsson L; Jiang X
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(2):164-170

Combination of Two Monoclonal Anti-Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase-4-Dependent Manner

Krishnamurthy A; Circiumaru A; Sun J; Kisten Y; Damberg P; Sakuraba K; Sandor K; Jarvoll P; Zhou T; Malmstrom V; Svensson CI; Hensvold A; Catrina AI; Klareskog L; Rethi B
Article: MOLECULAR IMMUNOLOGY. 2022;152:106-110

Five commercially-available antibodies react differentially with allelic forms of human HLA-DR beta chain

Houtman M; Dzebisashvili A; Dubnovitsky A; Kozhukh G; Ronnblom L; Klareskog L; Malmstrom V; Padyukov L
Article: RHEUMATOLOGY. 2022;61(12):4985-4990

Anti-citrullinated protein antibody specificities and pulmonary fibrosis in relation to genetic loci in early rheumatoid arthritis

Brink M; Ljung L; Hansson M; Ronnelid J; Holmdahl R; Skriner K; Serre G; Klareskog L; Rantapaa-Dahlqvist S
Article: NATURE GENETICS. 2022;54(11):1640-1651

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

Ishigaki K; Sakaue S; Terao C; Luo Y; Sonehara K; Yamaguchi K; Amariuta T; Too CL; Laufer VA; Scott IC; Viatte S; Takahashi M; Ohmura K; Murasawa A; Hashimoto M; Ito H; Hammoudeh M; Al Emadi S; Masri BK; Halabi H; Badsha H; Uthman IW; Wu X; Lin L; Li T; Plant D; Barton A; Orozco G; Verstappen SMM; Bowes J; MacGregor AJ; Honda S; Koido M; Tomizuka K; Kamatani Y; Tanaka H; Tanaka E; Suzuki A; Maeda Y; Yamamoto K; Miyawaki S; Xie G; Zhang J; Amos CI; Keystone E; Wolbink G; Van der Horst-Bruinsma I; Cui J; Liao KP; Carroll RJ; Lee H-S; Bang S-Y; Siminovitch KA; de Vries N; Alfredsson L; Rantapaa-Dahlqvist S; Karlson EW; Bae S-C; Kimberly RP; Edberg JC; Mariette X; Huizinga T; Dieude P; Schneider M; Kerick M; Denny JC; Matsuda K; Matsuo K; Mimori T; Matsuda F; Fujio K; Tanaka Y; Kumanogoh A; Traylor M; Lewis CM; Eyre S; Xu H; Saxena R; Arayssi T; Kochi Y; Ikari K; Harigai M; Gregersen PK; Yamamoto K; Bridges SLJ; Padyukov L; Martin J; Klareskog L; Okada Y; Raychaudhuri S
Article: BIOLOGICAL PSYCHIATRY GLOBAL OPEN SCIENCE. 2022;2(4):368-378

Common Genetic Variation and Age of Onset of Anorexia Nervosa

Watson HJ; Thornton LM; Yilmaz Z; Baker JH; Coleman JRI; Adan RAH; Alfredsson L; Andreassen OA; Ask H; Berrettini WH; Boehnke M; Boehm I; Boni C; Buehren K; Bulant J; Burghardt R; Chang X; Cichon S; Cone RD; Courtet P; Crow S; Crowley JJ; Danner UN; de Zwaan M; Dedoussis G; DeSocio JE; Dick DM; Dikeos D; Dina C; Djurovic S; Dmitrzak-Weglarz M; Docampo-Martinez E; Duriez P; Egberts K; Ehrlich S; Eriksson JG; Escaramis G; Esko T; Estivill X; Farmer A; Fernandez-Aranda F; Fichter MM; Foecker M; Foretova L; Forstner AJ; Frei O; Gallinger S; Giegling I; Giuranna J; Gonidakis F; Gorwood P; Gratacos M; Guillaume S; Guo Y; Hakonarson H; Hauser J; Havdahl A; Hebebrand J; Helder SG; Herms S; Herpertz-Dahlmann B; Herzog W; Hinney A; Huebel C; Hudson JI; Imgart H; Jamain S; Janout V; Jimenez-Murcia S; Jones IR; Julia A; Kalsi G; Kaminska D; Kaprio J; Karhunen L; Kas MJH; Keel PK; Kennedy JL; Keski-Rahkonen A; Kiezebrink K; Klareskog L; Klump KL; Knudsen GPS; La Via MC; Le Hellard S; Leboyer M; Li D; Lilenfeld L; Lin B; Lissowska J; Luykx J; Magistretti P; Maj M; Marsal S; Marshall CR; Mattingsdal M; Meulenbelt I; Micali N; Mitchell KS; Monteleone AM; Monteleone P; Myers R; Navratilova M; Ntalla I; O'Toole JK; Ophoff RA; Padyukov L; Pantel J; Papezova H; Pinto D; Raevuori A; Ramoz N; Reichborn-Kjennerud T; Ricca V; Ripatti S; Ripke S; Ritschel F; Roberts M; Rotondo A; Rujescu D; Rybakowski F; Scherag A; Scherer SW; Schmidt U; Scott LJ; Seitz J; Silen Y; Slachtova L; Slagboom PE; Slof-Op 't Landt MCT; Slopien A; Sorbi S; Swiatkowska B; Tortorella A; Tozzi F; Treasure J; Tsitsika A; Tyszkiewicz-Nwafor M; Tziouvas K; van Elburg AA; van Furth EF; Walton E; Widen E; Zerwas S; Zipfel S; Bergen AW; Boden JM; Brandt H; Crawford S; Halmi KA; Horwood LJ; Johnson C; Kaplan AS; Kaye WH; Mitchell JE; Olsen CM; Pearson JF; Pedersen NL; Strober M; Werge T; Whiteman DC; Woodside DB; Gordon S; Maguire S; Larsen JT; Parker R; Petersen LV; Jordan J; Kennedy M; Wade TD; Birgegard A; Lichtenstein P; Landen M; Martin NG; Mortensen PB; Breen G; Bulik CM
Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):203

Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis: results from the Swedish EIRA study

Hedenstierna L; Hedstrom AK; Klareskog L; Di Giuseppe D; Alfredsson L; Askling J; Ernestam S; Saevarsdottir S; Ljung L
Article: PAIN. 2022;163(8):1542-1559

Antibody-induced pain-like behavior and bone erosion: links to subclinical inflammation, osteoclast activity, and acid-sensing ion channel 3-dependent sensitization

Jurczak A; Delay L; Barbier J; Simon N; Krock E; Sandor K; Agalave NM; Rudjito R; Wigerblad G; Rogoz K; Briat A; Miot-Noirault E; Martinez-Martinez A; Bromme D; Gronwall C; Malmstrom V; Klareskog L; Khoury S; Ferreira T; Labrum B; Deval E; Miguel Jimenez-Andrade J; Marchand F; Svensson CI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(8):1085-1095

Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset

Saevarsdottir S; Stefansdottir L; Sulem P; Thorleifsson G; Ferkingstad E; Rutsdottir G; Glintborg B; Westerlind H; Grondal G; Loft IC; Sorensen SB; Lie BA; Brink M; Arlestig L; Arnthorsson AO; Baecklund E; Banasik K; Bank S; Bjorkman LI; Ellingsen T; Erikstrup C; Frei O; Gjertsson I; Gudbjartsson DF; Gudjonsson SA; Halldorsson GH; Hendricks O; Hillert J; Hogdall E; Jacobsen S; Jensen DV; Jonsson H; Kastbom A; Kockum I; Kristensen S; Kristjansdottir H; Larsen MH; Linauskas A; Hauge E-M; Loft AG; Ludviksson BR; Lund SH; Markusson T; Masson G; Melsted P; Moore KHS; Munk H; Nielsen KR; Norddahl GL; Oddsson A; Olafsdottir TA; Olason PI; Olsson T; Ostrowski SR; Horslev-Petersen K; Rognvaldsson S; Sanner H; Silberberg GN; Stefansson H; Sorensen E; Sorensen IJ; Turesson C; Bergman T; Alfredsson L; Kvien TK; Brunak S; Steinsson K; Andersen V; Andreassen OA; Rantapaa-Dahlqvist S; Hetland ML; Klareskog L; Askling J; Padyukov L; Pedersen OB; Thorsteinsdottir U; Jonsdottir I; Stefansson K
Article: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):178

Investigation of the association between coffee and risk of RA-results from the Swedish EIRA study

Westerlind H; Dukuzimana J; Lu X; Alfredsson L; Klareskog L; Di Giuseppe D
Article: ACR OPEN RHEUMATOLOGY. 2022;4(6):492-502

Unmet Needs in Rheumatoid Arthritis: A Subgroup of Patients With High Levels of Pain, Fatigue, and Psychosocial Distress 3 Years After Diagnosis

Lindqvist J; Alfredsson L; Klareskog L; Lampa J; Westerlind H
Article: RHEUMATOLOGY. 2022;61(4):1680-1689

Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis

Yoosuf N; Maciejewski M; Ziemek D; Jelinsky SA; Folkersen L; Muller M; Sahlstrom P; Vivar N; Catrina A; Berg L; Klareskog L; Padyukov L; Brynedal B
Article: RMD OPEN. 2022;8(1):e002018

Allergic conditions and risk of rheumatoid arthritis: a Swedish case-control study

Kronzer VL; Westerlind H; Alfredsson L; Crowson CS; Klareskog L; Holmqvist M; Askling J
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:804822

Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology

Sherina N; de Vries C; Kharlamova N; Sippl N; Jiang X; Brynedal B; Kindstedt E; Hansson M; Mathsson-Alm L; Israelsson L; Stalesen R; Saevarsdottir S; Holmdahl R; Hensvold A; Johannsen G; Eriksson K; Sallusto F; Catrina AI; Roennelid J; Groenwall C; Yucel-Lindberg T; Alfredsson L; Klareskog L; Piccoli L; Malmstroem V; Amara K; Lundberg K
Article: RMD OPEN. 2022;8(1):e001800

Sleep problems in rheumatoid arthritis over 12 years from diagnosis: results from the Swedish EIRA study

Lyne L; Akerstedt T; Alfredsson L; Lehtonen T; Saevarsdottir S; Klareskog L; Westerlind H
Article: FRONTIERS IN MEDICINE. 2022;9:774945

Rheumatic?-A Digital Diagnostic Decision Support Tool for Individuals Suspecting Rheumatic Diseases: A Multicenter Pilot Validation Study

Knevel R; Knitza J; Hensvold A; Circiumaru A; Bruce T; Evans S; Maarseveen T; Maurits M; Beaart-van de Voorde L; Simon D; Kleyer A; Johannesson M; Schett G; Huizinga T; Svanteson S; Lindfors A; Klareskog L; Catrina A
Article: FRONTIERS IN MEDICINE. 2022;9:824501

Prospective Studies on the Risk of Rheumatoid Arthritis: The European Risk RA Registry

Studenic P; Hensvold A; Kleyer A; van der Helm-van Mil A; Pratt AG; Sieghart D; Kroenke G; Williams R; de Souza S; Karlfeldt S; Johannesson M; Krogh NS; Klareskog L; Catrina AI
Article: SCIENTIFIC REPORTS. 2021;11(1):24512

Biased TCR gene usage in citrullinated Tenascin C specific T-cells in rheumatoid arthritis

Sharma RK; Boddul SV; Yoosuf N; Turcinov S; Dubnovitsky A; Kozhukh G; Wermeling F; Kwok WW; Klareskog L; Malmstrom V
Article: RMD OPEN. 2021;7(3):e001987

Effects of the COVID-19 pandemic on patients with inflammatory joint diseases in Sweden: from infection severity to impact on care provision

Bower H; Frisell T; di Giuseppe D; Delcoigne B; Ahlenius G-M; Baecklund E; Chatzidionysiou K; Feltelius N; Forsblad-d'Elia H; Kastbom A; Klareskog L; Lindqvist E; Lindstrom U; Turesson C; Sjowall C; Askling J
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):209

Is tea consumption associated with reduction of risk of rheumatoid arthritis? A Swedish case-control study

Westerlind H; Palmqvist I; Saevarsdottir S; Alfredsson L; Klareskog L; Di Giuseppe D
Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(8):1086-1093

Impact of the COVID-19 pandemic on morbidity and mortality in patients with inflammatory joint diseases and in the general population: a nationwide Swedish cohort study

Bower H; Frisell T; Di Giuseppe D; Delcoigne B; Ahlenius G-M; Baecklund E; Chatzidionysiou K; Feltelius N; Forsblad-d'Elia H; Kastbom A; Klareskog L; Lindqvist E; Lindstrom U; Turesson C; Sjowall C; Askling J
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021;39(4):879-882

Rheumatoid arthritis autoantibodies and their association with age and sex

Pertsinidou E; Manivel VA; Westerlind H; Klareskog L; Alfredsson L; Mathsson-Alm L; Hansson M; Saevatsdottir S; Askling J; Ronnelid J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2021;50(4):271-279

Widespread non-joint pain in early rheumatoid arthritis

Schelin MEC; Westerlind H; Lindqvist J; Englid E; Israelsson L; Skillgate E; Klareskog L; Alfredsson L; Lampa J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2021;50(3):178-182

Social stressors and risk of rheumatoid arthritis and their relationship to known modifiable risk factors: results from the Swedish EIRA study

Hedenstierna L; Opava CH; Askling J; Jiang X; Ernestam S; Alfredsson L; Klareskog L; Saevarsdottir S
Article: SCIENCE IMMUNOLOGY. 2021;6(58):eabe0896

The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR

Lim JJ; Jones CM; Loh TJ; Ting YT; Zareie P; Loh KL; Felix NJ; Suri A; McKinnon M; Stevenaert F; Sharma RK; Klareskog L; Malmstrom V; Baker DG; Purcell AW; Reid HH; La Gruta NL; Rossjohn J
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):108

Age at menarche, age at natural menopause, and risk of rheumatoid arthritis - a Mendelian randomization study

Zhu J; Niu Z; Alfredsson L; Klareskog L; Padyukov L; Jiang X
Article: ARTHRITIS & RHEUMATOLOGY. 2021;73(2):203-211

Obesity-Related Traits and the Development of Rheumatoid Arthritis: Evidence From Genetic Data

Tang B; Shi H; Alfredsson L; Klareskog L; Padyukov L; Jiang X
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):46

The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study

Tan LK; Too CL; Diaz-Gallo LM; Wahinuddin S; Lau IS; Heselynn H; Nor-Shuhaila S; Gun SC; Eashwary M; Mohd-Shahrir MS; Ainon MM; Azmillah R; Muhaini O; Shahnaz M; Alfredsson L; Klareskog L; Padyukov L
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:707217

Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients

Houtman M; Hesselberg E; Ronnblom L; Klareskog L; Malmstrom V; Padyukov L
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:627986

A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis

Gronwall C; Liljefors L; Bang H; Hensvold AH; Hansson M; Mathsson-Alm L; Israelsson L; Joshua V; Svard A; Stalesen R; Titcombe PJ; Steen J; Piccoli L; Sherina N; Clavel C; Svenungsson E; Gunnarsson I; Saevarsdottir S; Kastbom A; Serre G; Alfredsson L; Malmstrom V; Ronnelid J; Catrina AI; Lundberg K; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2021;73(1):61-68

Respiratory Diseases as Risk Factors for Seropositive and Seronegative Rheumatoid Arthritis and in Relation to Smoking

Kronzer VL; Westerlind H; Alfredsson L; Crowson CS; Nyberg F; Tornling G; Klareskog L; Holmqvist M; Askling J
Article: JOURNAL OF TRANSLATIONAL AUTOIMMUNITY. 2021;4:100087

In vitro and ex vivo functional characterization of human HLA-DRB1*04 restricted T cell receptors

Boddul SV; Sharma RK; Dubnovitsky A; Raposo B; Gerstner C; Shen Y; Iyer VS; Kasza Z; Kwok WW; Winkler AR; Klareskog L; Malmstrom V; Bettini M; Wermeling F
Article: ARTHRITIS & RHEUMATOLOGY. 2020;72(10):1643-1657

Different Hierarchies of Anti-Modified Protein Autoantibody Reactivities in Rheumatoid Arthritis

Sahlstroem P; Hansson M; Steen J; Amara K; Titcombe PJ; Forsstrom B; Stalesen R; Israelsson L; Piccoli L; Lundberg K; Klareskog L; Mueller DL; Catrina AI; Skriner K; Malmstrom V; Gronwall C
Article: ARTHRITIS & RHEUMATOLOGY. 2020;72(10):1658-1667

Anti-Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis

Westerlind H; Ronnelid J; Hansson M; Alfredsson L; Mathsson-Alm L; Serre G; Cornillet M; Holmdahl R; Jakobsson P-J; Skriner K; Klareskog L; Saevarsdottir S; Askling J
Article: NATURE. 2020;584(7822):619-623

FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease

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Article: RMD OPEN. 2020;6(2):e001211

Considerations for improving quality of care of patients with rheumatoid arthritis and associated comorbidities

Kvien TK; Balsa A; Betteridge N; Buch MH; Durez P; Favalli EG; Favier G; Gabay C; Geenen R; Gouni-Berthold I; van den Hoogen F; Kent A; Klareskog L; Ostergaard M; Pavelka K; Polido Pereira J; Semb AG; Skold M; Dougados M
Article: JMIR MHEALTH AND UHEALTH. 2020;8(5):e17507

Toward Earlier Diagnosis Using Combined eHealth Tools in Rheumatology: The Joint Pain Assessment Scoring Tool (JPAST) Project

Knitza J; Knevel R; Raza K; Bruce T; Eimer E; Gehring I; Mathsson-Alm L; Poorafshar M; Hueber AJ; Schett G; Johannesson M; Catrina A; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2020;79(5):553-555

Disruptive innovation in rheumatology: new networks of global public-private partnerships are needed to take advantage of scientific progress

Huizinga TWJ; Holers VM; Anolik J; Brenner MB; Buckley CD; Bykerk V; Connolly SE; Deane KD; Guo J; Hodge M; Hoffmann S; Nestle F; Pitzalis C; Raychaudhuri S; Yamamoto K; Li Z; Klareskog L
Article: SCIENTIFIC REPORTS. 2019;9(1):19995

Rheumatoid arthritis patients display B-cell dysregulation already in the naive repertoire consistent with defects in B-cell tolerance

Wang Y; Lloyd KA; Melas I; Zhou D; Thyagarajan R; Lindqvist J; Hansson M; Svard A; Mathsson-Alm L; Kastbom A; Lundberg K; Klareskog L; Catrina AI; Rapecki S; Malmstrom V; Gronwall C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(12):1621-1631

Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts

Sun M; Rethi B; Krishnamurthy A; Joshua V; Circiumaru A; Hensvold AH; Ossipova E; Gronwall C; Liu Y; Engstrom M; Catrina SB; Steen J; Malmstrom V; Klareskog L; Svensson C; Ospelt C; Wahamaa H; Catrina AI
Article: BIOLOGICAL PSYCHIATRY. 2019;86(8):577-586

Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches

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Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(3):616-624

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype

Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Article: ARTHRITIS & RHEUMATOLOGY. 2019;71(9):1504-1511

Complex Relationships of Smoking, HLA-DRB1 Genes, and Serologic Profiles in Patients With Early Rheumatoid Arthritis: Update From a Swedish Population-Based Case-Control Study

Hedstrom AK; Ronnelid J; Klareskog L; Alfredsson L
Article: NATURE GENETICS. 2019;51(8):1207-1214

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

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Article: MOLECULAR NEUROBIOLOGY. 2019;56(7):5146-5156

Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa

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Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(6):773-780

Sequencing of the MHC region defines HLA-DQA1 as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population

Guo J; Zhang T; Cao H; Li X; Liang H; Liu M; Zou Y; Zhang Y; Wang Y; Sun X; Hu F; Du Y; Mo X; Liu X; Yang Y; Yang H; Wu X; Zhang X; Jia H; Jiang H; Hou Y; Liu X; Su Y; Zhang M; Yang H; Wang J; Sun L; Liu L; Padyukov L; Lai L; Yamamoto K; Zhang X; Klareskog L; Xu X; Li Z
Article: JOURNAL OF CLINICAL MEDICINE. 2019;8(5):E630-630

Periodontal Health and Oral Microbiota in Patients with Rheumatoid Arthritis

Eriksson K; Fei G; Lundmark A; Benchimol D; Lee L; Hu YOO; Kats A; Saevarsdottir S; Catrina AI; Klinge B; Andersson AF; Klareskog L; Lundberg K; Jansson L; Yucel-Lindberg T
Article: ARTHRITIS & RHEUMATOLOGY. 2019;71(3):340-350

Generation and Characterization of Anti-Citrullinated Protein Antibody-Producing B Cell Clones From Rheumatoid Arthritis Patients

Germar K; Fehres CM; Scherer HU; van Uden N; Pollastro S; Yeremenko N; Hansson M; Kerkman PF; van der Voort EIH; Reed E; Maassen H; Kwakkenbos MJ; Bakker AQ; Klareskog L; Malmstrom V; de Vries N; Toes REM; Lundberg K; Spits H; Baeten DL
Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(3):320-327

Risk of serious infections in patients with rheumatoid arthritis treated in routine care with abatacept, rituximab and tocilizumab in Denmark and Sweden

Gron KL; Arkema EV; Glintborg B; Mehnert F; Ostergaard M; Dreyer L; Norgaard M; Krogh NS; Askling J; Hetland ML; Askling J; Klareskog L; Feltelius N; Baecklund E; Sjowall C; Rantapaa-Dahlqvist S; Forsblad-d'Elia H; Jacobsson L; Turesson C; Lindqvist E; Nisell R
Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(3):311-319

Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases

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Article: ARTHRITIS & RHEUMATOLOGY. 2019;71(2):196-209

Recognition of Amino Acid Motifs, Rather Than Specific Proteins, by Human Plasma Cell-Derived Monoclonal Antibodies to Posttranslationally Modified Proteins in Rheumatoid Arthritis

Steen J; Forsstroem B; Sahlstroem P; Odowd V; Israelsson L; Krishnamurthy A; Badreh S; Alm LM; Compson J; Ramskold D; Ndlovu W; Rapecki S; Hansson M; Titcombe PJ; Bang H; Mueller DL; Catrina AI; Gronwall C; Skriner K; Nilsson P; Lightwood D; Klareskog L; Malmstrom V
Article: ARTHRITIS & RHEUMATOLOGY. 2019;71(2):210-221

Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies

Ge C; Xu B; Liang B; Lonnblom E; Lundstrom SL; Zubarev RA; Ayoglu B; Nilsson P; Skogh T; Kastbom A; Malmstrom V; Klareskog L; Toes REM; Rispens T; Dobritzsch D; Holmdahl R
Article: RHEUMATOLOGY. 2019;58(8):1367-1377

Comparative effectiveness of abatacept, rituximab, tocilizumab and TNFi biologics in RA: results from the nationwide Swedish register

Frisell T; Dehlin M; Di Giuseppe D; Feltelius N; Turesson C; Askling J; Ernestam S; Klareskog L; Nisell R; Baecklund E; Kastbom A; Jacobsson L; Lindqvist E; d'Elia HF; Rantapaa-Dahlqvist S
Article: RMD OPEN. 2019;5(2):e000946

Antibodies against citrullinated peptides are associated with clinical and radiological outcomes in patients with early rheumatoid arthritis: a prospective longitudinal inception cohort study

Boman A; Brink M; Lundquist A; Hansson M; Mathsson-Alm L; Ronnelid J; Berglin E; Holmdahl R; Skriner K; Serre G; Klareskog L; Rantapaa-Dahlqvist S
Article: RMD OPEN. 2019;5(2):e000978

Occupational exposure to asbestos and silica and risk of developing rheumatoid arthritis: findings from a Swedish population-based case-control study

Ilar A; Klareskog L; Saevarsdottir S; Wiebert P; Askling J; Gustaysson P; Alfredsson L
Article: RMD OPEN. 2019;5(1):e000893

Interplay between alcohol, smoking and HLA genes in RA aetiology

Hedstrom AK; Hossjer O; Klareskog L; Alfredsson L
Article: RMD OPEN. 2019;5(1):e000856

Interplay between obesity and smoking with regard to RA risk

Hedstrom AK; Klareskog L; Alfredsson L
Article: ARTHRITIS & RHEUMATOLOGY. 2018;70(12):1933-1945

Pathogenic Citrulline-Multispecific B Cell Receptor Clades in Rheumatoid Arthritis

Titcombe PJ; Wigerblad G; Sippl N; Zhang N; Shmagel AK; Sahlstrom P; Zhang Y; Barsness LO; Ghodke-Puranik Y; Baharpoor A; Hansson M; Israelsson L; Skriner K; Niewold TB; Klareskog L; Svensson CI; Amara K; Malmstrom V; Mueller DL
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(10):1454-1462

Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis

Diaz-Gallo L-M; Ramskold D; Shchetynsky K; Folkersen L; Chemin K; Brynedal B; Uebe S; Okada Y; Alfredsson L; Klareskog L; Padyukov L
Article: NATURE GENETICS. 2018;50(10):1366-1374

Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes

Westra H-J; Martinez-Bonet M; Onengut-Gumuscu S; Lee A; Luol Y; Teslovich N; Worthington J; Martin J; Huizinga T; Klareskog L; Rantapaa-Dahlqvist S; Chen W-M; Quinlan A; Todd JA; Eyre S; Nigrovic PA; Regersen PKG; Rich SS; Raychaudhuri S
Article: JOURNAL OF AUTOIMMUNITY. 2018;92:47-56

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint

Pieper J; Dubnovitsky A; Gerstner C; James EA; Rieck M; Kozhukh G; Tandre K; Pellegrino S; Gebe JA; Ronnblom L; Sandalova T; Kwok WW; Klareskog L; Buckner JH; Achour A; Malmstrom V
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2018;16(1):214

Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis

Engstrom M; Eriksson K; Lee L; Hermansson M; Johansson A; Nicholas AP; Gerasimcik N; Lundberg K; Klareskog L; Catrina AI; Yucel-Lindberg T
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2018;47(4):270-275

Anti-cyclic citrullinated peptide antibodies, other common autoantibodies, and smoking as risk factors for lymphoma in patients with rheumatoid arthritis

Baecklund E; Backlin C; Ronnelid J; Toes R; Huizinga TWJ; Ahlin E; Askling J; Hochberg FH; Klareskog L; Kay J; Smedby KE
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(7):970-972

Exposure to passive smoking and rheumatoid arthritis risk: results from the Swedish EIRA study

Hedstrom AK; Klareskog L; Alfredsson L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2018;48(6):1030-1045

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection

Lloyd KA; Steen J; Amara K; Titcombe PJ; Israelsson L; Lundstrom SL; Zhou D; Zubarev RA; Reed E; Piccoli L; Gabay C; Lanzavecchia A; Baeten D; Lundberg K; Mueller DL; Klareskog L; Malmstrom V; Gronwall C
Article: ARTHRITIS CARE & RESEARCH. 2018;70(4):499-509

Occupation and Risk of Developing Rheumatoid Arthritis: Results From a Population-Based Case-Control Study

Ilar A; Alfredsson L; Wiebert P; Klareskog L; Bengtsson C
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2018;33(4):415-423

Smoking and susceptibility to rheumatoid arthritis in a Swedish population-based case-control study

Hedstrom AK; Stawiarz L; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(2):203-211

Anticitrullinated protein/peptide antibody multiplexing defines an extended group of ACPA-positive rheumatoid arthritis patients with distinct genetic and environmental determinants

Ronnelid J; Hansson M; Mathsson-Alm L; Cornillet M; Reed E; Jakobsson P-J; Alfredsson L; Holmdahl R; Skriner K; Serre G; Lundberg K; Klareskog L
Article: ARTHRITIS CARE & RESEARCH. 2018;70(2):205-212

Dietary Intake of Polyunsaturated Fatty Acids and Pain in Spite of Inflammatory Control Among Methotrexate-Treated Early Rheumatoid Arthritis Patients

Lourdudoss C; Di Giuseppe D; Wolk A; Westerlind H; Klareskog L; Alfredsson L; van Vollenhoven RF; Lampa J
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:451

A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Human with Arthritis

Tong D; Lonnblom E; Yau ACY; Nandakumar KS; Liang B; Ge C; Viljanen J; Li L; Balan M; Klareskog L; Chagin AS; Gjertsson I; Kihlberg J; Zhao M; Holmdahl R
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:3033

Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis

Lloyd KA; Wigerblad G; Sahlstrom P; Garimella MG; Chemin K; Steen J; Titcombe PJ; Marklein B; Zhou D; Stalesen R; Ossipova E; Lundqvist C; Ekwall O; Ronnelid J; Mueller DL; Karlsson MCI; Kaplan MJ; Skriner K; Klareskog L; Wermeling F; Malmstrom V; Gronwall C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(11):1845-1852

Oral contraceptives, breastfeeding and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study

Orellana C; Saevarsdottir S; Klareskog L; Karlson EW; Alfredsson L; Bengtsson C
Article: JOURNAL OF AUTOIMMUNITY. 2017;84:29-45

Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis

Gronwall C; Amara K; Hardt U; Krishnamurthy A; Steen J; Engstrom M; Sun M; Ytterberg AJ; Zubarev RA; Scheel-Toellner D; Greenberg JD; Klareskog L; Catrina AI; Malmstrom V; Silverman GJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(10):1755-1763

H1N1 vaccination in Sjogren's syndrome triggers polyclonal B cell activation and promotes autoantibody production

Brauner S; Folkersen L; Kvarnstrom M; Meisgen S; Petersen S; Franzen-Malmros M; Mofors J; Brokstad KA; Klareskog L; Jonsson R; Westerberg LS; Trollmo C; Malmstrom V; Ambrosi A; Kuchroo VK; Nordmark G; Wahren-Herlenius M
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2017;174(9):850-858

Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa

Duncan L; Yilmaz Z; Gaspar H; Walters R; Goldstein J; Anttila V; Bulik-Sullivan B; Ripke S; Thornton L; Daly M; Sullivan PF; Zeggini E; Breen G; Bulik CM; Adan R; Alfredsson L; Ando T; Andreassen O; Aschauer H; Baker J; Barrett J; Bencko V; Bergen A; Berrettini W; Birgegard A; Boni C; Perica VB; Brandt H; Burghardt R; Carlberg L; Cassina M; Cesta C; Cichon S; Clementi M; Cohen-Woods S; Coleman J; Cone R; Courtet P; Crawford S; Crow S; Crowley J; Danner U; Davis O; de Zwaan M; Dedoussis G; Degortes D; DeSocio J; Dick D; Dikeos D; Dina C; Ding B; Dmitrzak-Weglarz M; Docampo E; Egberts K; Ehrlich S; Escaramis G; Esko T; Espeseth T; Estivill X; Favaro A; Fernandez-Aranda F; Fichter M; Finan C; Fischer K; Floyd J; Foecker M; Foretova L; Forzan M; Fox C; Franklin C; Gaborieau V; Gallinger S; Gambaro G; Giegling I; Gonidakis F; Gorwood P; Gratacos M; Guillaume S; Guo Y; Hakonarson H; Halmi K; Harrison R; Hatzikotoulas K; Hauser J; Hebebrand J; Helder S; Hendriks J; Herms S; Herpertz-Dahlmann B; Herzog W; Hilliard C; Huckins L; Hudson J; Huemer J; Imgart H; Inoko H; Jall S; Jamain S; Janout V; Jimenez-Murcia S; Johnson C; Jordan J; Julia A; Jureus A; Kalsi G; Kaplan A; Kaprio J; Karhunen L; Karwautz A; Kas M; Kaye W; Kennedy M; Kennedy J; Keski-Rahkonen A; Kiezebrink K; Kim Y-R; Klareskog L; Klump K; Knudsen GP; Koeleman B; Koubek D; La Via M; Landen M; Le Hellard S; Leboyer M; Levitan R; Li D; Lichtenstein P; Lilenfeld L; Lissowska J; Lundervold A; Magistretti P; Maj M; Mannik K; Marsal S; Kaminska D; Martin N; Mattingsdal M; McDevitt S; McGuffin P; Merl E; Metspalu A; Meulenbelt I; Micali N; Mitchell J; Mitchell K; Monteleone P; Monteleone AM; Montgomery G; Mortensen P; Munn-Chernoff M; Mueller T; Nacmias B; Navratilova M; Nilsson I; Norring C; Ntalla I; Ophoff R; O'Toole J; Palotie A; Pantel J; Papezova H; Parker R; Pinto D; Rabionet R; Raevuori A; Rajewski A; Ramoz N; Rayner NW; Reichborn-Kjennerud T; Ricca V; Ripatti S; Ritschel F; Roberts M; Rotondo A; Rujescu D; Rybakowski F; Santonastaso P; Scherag A; Scherer S; Schmidt U; Schork N; Schosser A; Scott L; Seitz J; Slachtova L; Sladek R; Slagboom PE; Slof-Op 't Landt M; Slopien A; Smith T; Soranzo N; Sorbi S; Southam L; Steen V; Strengman E; Strober M; Szatkiewicz J; Szeszenia-Dabrowska N; Tachmazidou I; Tenconi E; Tortorella A; Tozzi F; Treasure J; Tschop M; Tsitsika A; Tziouvas K; van Elburg A; van Furth E; Wade T; Wagner G; Walton E; Watson H; Wichmann H-E; Widen E; Woodside DB; Yanovski J; Yao S; Zerwas S; Zipfel S; Thornton L; Hinney A; Daly M; Sullivan PF; Zeggini E; Breen G; Bulik CM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(9):1529-1536

Anticollagen type II antibodies are associated with an acute onset rheumatoid arthritis phenotype and prognosticate lower degree of inflammation during 5 years follow-up

Manivel VA; Mullazehi M; Padyukov L; Westerlind H; Klareskog L; Alfredsson L; Saevarsdottir S; Ronnelid J
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):182

IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis

Lundstrom SL; Hensvold AH; Rutishauser D; Klareskog L; Ytterberg AJ; Zubarev RA; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):71

DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis

Meng W; Zhu Z; Jiang X; Too CL; Uebe S; Jagodic M; Kockum I; Murad S; Ferrucci L; Alfredsson L; Zou H; Klareskog L; Feinberg AP; Ekstrom TJ; Padyukov L; Liu Y
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):19

Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis

Shchetynsky K; Diaz-Gallo L-M; Folkersen L; Hensvold AH; Catrina AI; Berg L; Klareskog L; Padyukov L
Article: RMD OPEN. 2017;3(1):e000324

Physical workload is associated with increased risk of rheumatoid arthritis: results from a Swedish population-based case-control study.

Zeng P; Klareskog L; Alfredsson L; Bengtsson C
Article: RMD OPEN. 2017;3(2):e000475

Relationship between shift work and the onset of rheumatoid arthritis.

Hedström AK; Åkerstedt T; Klareskog L; Alfredsson L
Article: RMD OPEN. 2017;3(2):e000488

Working in cold environment and risk of developing rheumatoid arthritis: results from the Swedish EIRA case-control study.

Zeng P; Bengtsson C; Klareskog L; Alfredsson L
Article: OSTEOARTHRITIS AND CARTILAGE. 2017;25(1):157-165

An in vivo cross-linkable hyaluronan gel with inherent anti-inflammatory properties reduces OA cartilage destruction in female mice subjected to cruciate ligament transection

Aulin C; Lundback P; Palmblad K; Klareskog L; Harris HE
Article: ARTHRITIS & RHEUMATOLOGY. 2017;69(1):58-69

Differences in the Spectrum of Anti-Citrullinated Protein Antibody Fine Specificities Between Malaysian and Swedish Patients With Rheumatoid Arthritis: Implications for Disease Pathogenesis

Too CL; Murad S; Hansson M; Alm LM; Dhaliwal JS; Holmdahl R; Jakobsson P-J; Alfredsson L; Klareskog L; Ronnelid J; Padyukov L
Article: GENES AND IMMUNITY. 2017;18(1):48-56

VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis

Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Petit-Teixeira E; Cornelis F; Saoudi A; Fournie GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Article: GENOME MEDICINE. 2016;8(1):124

High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis

Gomez-Cabrero D; Almgren M; Sjoholm LK; Hensvold AH; Ringh MV; Tryggvadottir R; Kere J; Scheynius A; Acevedo N; Reinius L; Taub MA; Montano C; Aryee MJ; Feinberg JI; Feinberg AP; Tegner J; Klareskog L; Catrina AI; Ekstrom TJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(10):1891-1898

Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA

van Heemst J; Hensvold AH; Jiang X; van Steenbergen H; Klareskog L; Huizinga TWJ; van der Helm-van Mil A; Catrina AI; Toes REM; Lundberg K; van der Woude D
Article: MOLECULAR MEDICINE. 2016;22:322-328

Integration of Known DNA, RNA and Protein Biomarkers Provides Prediction of Anti-TNF Response in Rheumatoid Arthritis: Results from the COMBINE Study

Folkersen L; Brynedal B; Diaz-Gallo LM; Ramskold D; Shchetynsky K; Westerlind H; Sundstrom Y; Schepis D; Hensvold A; Vivar N; Eloranta M-L; Ronnblom L; Brunak S; Malmstrom V; Catrina A; Moerch UGW; Klareskog L; Padyukov L; Berg L
Article: NATURE COMMUNICATIONS. 2016;7:12460

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Sieberts SK; Zhu F; Garcia-Garcia J; Stahl E; Pratap A; Pandey G; Pappas D; Aguilar D; Anton B; Bonet J; Eksi R; Fornes O; Guney E; Li H; Marin MA; Panwar B; Planas-Iglesias J; Poglayen D; Cui J; Falcao AO; Suver C; Hoff B; Balagurusamy VSK; Dillenberger D; Neto EC; Norman T; Aittokallio T; Ammad-ud-din M; Azencott C-A; Bellon V; Boeva V; Bunte K; Chheda H; Cheng L; Corander J; Dumontier M; Goldenberg A; Gopalacharyulu P; Hajiloo M; Hidru D; Jaiswal A; Kaski S; Khalfaoui B; Khan SA; Kramer ER; Marttinen P; Mezlini AM; Molparia B; Pirinen M; Saarela J; Samwald M; Stoven V; Tang H; Tang J; Torkamani A; Vert J-P; Wang B; Wang T; Wennerberg K; Wineinger NE; Xiao G; Xie Y; Yeung R; Zhan X; Zhao C; Greenberg J; Kremer J; Michaud K; Barton A; Coenen M; Mariette X; Miceli C; Shadick N; Weinblatt M; de Vries N; Tak PP; Gerlag D; Huizinga TWJ; Kurreeman F; Allaart CF; Bridges SLJ; Criswell L; Moreland L; Klareskog L; Saevarsdottir S; Padyukov L; Gregersen PK; Friend S; Plenge R; Stolovitzky G; Oliva B; Guan Y; Mangravite LM
Article: ARTHRITIS CARE & RESEARCH. 2016;68(8):1061-1068

Remaining Pain in Early Rheumatoid Arthritis Patients Treated With Methotrexate

Altawil R; Saevarsdottir S; Wedren S; Alfredsson L; Klareskog L; Lampa J
Article: NATURE GENETICS. 2016;48(7):803-810

A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases

Han B; Pouget JG; Slowikowski K; Stahl E; Lee CH; Diogo D; Hu X; Park YR; Kim E; Gregersen PK; Dahlqvist SR; Worthington J; Martin J; Eyre S; Klareskog L; Huizinga T; Chen W-M; Onengut-Gumuscu S; Rich SS; Wray NR; Raychaudhuri S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(6):997-1002

Occupational exposure to textile dust increases the risk of rheumatoid arthritis: results from a Malaysian population-based case-control study

Too CL; Muhamad NA; Ilar A; Padyukov L; Alfredsson L; Klareskog L; Murad S; Bengtsson C
Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(5):1124-1135

A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis

Chemin K; Pollastro S; James E; Ge C; Albrecht I; Herrath J; Gerstner C; Tandre K; Rizzi TS; Ronnblom L; Catrina A; Holmdahl R; Klareskog L; de Vries N; Malmstrom V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):730-738

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

Wigerblad G; Bas DB; Fernades-Cerqueira C; Krishnamurthy A; Nandakumar KS; Rogoz K; Kato J; Sandor K; Su J; Miguel Jimenez-Andrade J; Finn A; Farinotti AB; Amara K; Lundberg K; Holmdahl R; Jakobsson P-J; Malmstrom V; Catrina AI; Klareskog L; Svensson CI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):721-729

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

Krishnamurthy A; Joshua V; Hensvold AH; Jin T; Sun M; Vivar N; Ytterberg AJ; Engstrom M; Fernandes-Cerqueira C; Amara K; Magnusson M; Wigerblad G; Kato J; Jimenez-Andrade JM; Tyson K; Rapecki S; Lundberg K; Catrina S-B; Jakobsson P-J; Svensson C; Malmstrom V; Klareskog L; Wahamaa H; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2016;18:43

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

Brink M; Hansson M; Mathsson-Alm L; Wijayatunga P; Verheul MK; Trouw LA; Holmdahl R; Ronnelid J; Klareskog L; Rantapaa-Dahlqvist S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(2):356-361

Changes in the anticitrullinated peptide antibody response in relation to therapeutic outcome in early rheumatoid arthritis: results from the SWEFOT trial

Kastbom A; Forslind K; Ernestam S; Geborek P; Karlsson JA; Petersson IF; Saevarsdottir S; Klareskog L; van Vollenhoven RF; Lundberg K
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(1):317-320

Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study

Yarwood A; Viatte S; Okada Y; Plenge R; Yamamoto K; Barton A; Symmons D; Raychaudhuri S; Klareskog L; Gregersen P; Worthington J; Eyre S
Article: RHEUMATOLOGY. 2016;55(1):149-155

An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis

Jiang X; Kallberg H; Chen Z; Arlestig L; Rantapaa-Dahlqvist S; Davila S; Klareskog L; Padyukov L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(1):183-189

Familial aggregation of arthritis-related diseases in seropositive and seronegative rheumatoid arthritis: a register-based case-control study in Sweden

Frisell T; Hellgren K; Alfredsson L; Raychaudhuri S; Klareskog L; Askling J
Article: PLOS ONE. 2016;11(5):e0155956

Prevalence of Periodontitis in Patients with Established Rheumatoid Arthritis: A Swedish Population Based Case-Control Study

Eriksson K; Nise L; Kats A; Luttropp E; Catrina AI; Askling J; Jansson L; Alfredsson L; Klareskog L; Lundberg K; Yucel-Lindberg T
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17:358

Parity influences the severity of ACPA-negative early rheumatoid arthritis: a cohort study based on the Swedish EIRA material

Pikwer M; Orellana C; Kallberg H; Pikwer A; Turesson C; Klareskog L; Alfredsson L; Saevarsdottir S; Bengtsson C
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17:317

Higher education is associated with a better rheumatoid arthritis outcome concerning for pain and function but not disease activity: results from the EIRA cohort and Swedish rheumatology register

Jiang X; Sandberg MEC; Saevarsdottir S; Klareskog L; Alfredsson L; Bengtsson C
Article: ARTHRITIS & RHEUMATOLOGY. 2015;67(10):2611-2623

Interactions Between Amino Acid-Defined Major Histocompatibility Complex Class II Variants and Smoking in Seropositive Rheumatoid Arthritis

Kim K; Jiang X; Cui J; Lu B; Costenbader KH; Sparks JA; Bang S-Y; Lee H-S; Okada Y; Raychaudhuri S; Alfredsson L; Bae S-C; Klareskog L; Karlson EW
Article: NATURE GENETICS. 2015;47(9):1085-1090

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

Lenz TL; Deutsch AJ; Han B; Hu X; Okada Y; Eyre S; Knapp M; Zhernakova A; Huizinga TWJ; Abecasis G; Becker J; Boeckxstaens GE; Chen W-M; Franke A; Gladman DD; Gockel I; Gutierrez-Achury J; Martin J; Nair RP; Noethen MM; Onengut-Gumuscu S; Rahman P; Rantapaa-Dahlqvist S; Stuart PE; Tsoi LC; van Heel DA; Worthington J; Wouters MM; Klareskog L; Elder JT; Gregersen PK; Schumacher J; Rich SS; Wijmenga C; Sunyaev SR; de Bakker PIW; Raychaudhuri S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(9):1772-1777

Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation

Ytterberg AJ; Joshua V; Reynisdottir G; Tarasova NK; Rutishauser D; Ossipova E; Hensvold AH; Eklund A; Skold CM; Grunewald J; Malmstrom V; Jakobsson PJ; Ronnelid J; Padyukov L; Zubarev RA; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(8):1522-1529

Improved performance of epidemiologic and genetic risk models for rheumatoid arthritis serologic phenotypes using family history

Sparks JA; Chen C-Y; Jiang X; Askling J; Hiraki LT; Malspeis S; Klareskog L; Alfredsson L; Costenbader KH; Karlson EW
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):155

Targeting of anti-citrullinated protein/peptide antibodies in rheumatoid arthritis using peptides mimicking endogenously citrullinated fibrinogen antigens

Fernandes-Cerqueira C; Ossipova E; Gunasekera S; Hansson M; Mathsson L; Catrina AI; Sommarin Y; Klareskog L; Lundberg K; Ronnelid J; Goransson U; Jakobsson P-J
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):125

Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis

Kokkonen H; Brink M; Hansson M; Lassen E; Mathsson-Alm L; Holmdahl R; Ronnelid J; Klareskog L; Rantapaa-Dahlqvist S
Article: ARTHRITIS & RHEUMATOLOGY. 2015;67(8):2032-2037

Associations With Smoking and Shared Epitope Differ Between IgA- and IgG-Class Antibodies to Cyclic Citrullinated Peptides in Early Rheumatoid Arthritis

Svard A; Skogh T; Alfredsson L; Ilar A; Klareskog L; Bengtsson C; Kastbom A
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2015;30(5):449-457

Postmenopausal hormone therapy and the risk of rheumatoid arthritis: results from the Swedish EIRA population-based case-control study

Orellana C; Saevarsdottir S; Klareskog L; Karlson EW; Alfredsson L; Bengtsson C
Article: CLINICAL IMMUNOLOGY. 2015;158(1):19-28

Gene-gene interaction and RNA splicing profiles of MAP2K4 gene in rheumatoid arthritis

Shchetynsky K; Protsyuk D; Ronninger M; Diaz-Gallo L-M; Klareskog L; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(5):904-907

Recent infections are associated with decreased risk of rheumatoid arthritis: a population-based case-control study

Sandberg MEC; Bengtsson C; Klareskog L; Alfredsson L; Saevarsdottir S
Article: NATURE COMMUNICATIONS. 2015;6:6651

Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss

Harre U; Lang SC; Pfeifle R; Rombouts Y; Fruhbeisser S; Amara K; Bang H; Lux A; Koeleman CA; Baum W; Dietel K; Groehn F; Malmstroem V; Klareskog L; Kroenke G; Kocijan R; Nimmerjahn F; Toes REM; Herrmann M; Scherer HU; Schett G
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(3):e15

A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides

Bossini-Castillo L; de Kovel C; Kallberg H; van 't Slot R; Italiaander A; Coenen M; Tak PP; Posthumus MD; Wijmenga C; Huizinga T; van der Helm-van Mil AHM; Stoeken-Rijsbergen G; Rodriguez-Rodriguez L; Balsa A; Gonzalez-Alvaro I; Angel Gonzalez-Gay M; Gomez-Vaquero C; Franke B; Vermeulen S; van der Horst-Bruinsma IE; Dijkmans BAC; Wolbink GJ; Ophoff RA; Maehlen MT; van Riel P; Merriman M; Klareskog L; Lie BA; Merriman T; Crusius JBA; Brouwer E; Martin J; de Vries N; Toes R; Padyukov L; Koeleman BPC
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(3):e13

High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci

Kim K; Bang S-Y; Lee H-S; Cho S-K; Choi C-B; Sung Y-K; Kim T-H; Jun J-B; Yoo DH; Kang YM; Kim S-K; Suh C-H; Shim S-C; Lee S-S; Lee J; Chung WT; Choe J-Y; Shin HD; Lee J-Y; Han B-G; Nath SK; Eyre S; Bowes J; Pappas DA; Kremer JM; Gonzalez-Gay MA; Rodriguez-Rodriguez L; Arlestig L; Okada Y; Diogo D; Liao KP; Karlson EW; Raychaudhuri S; Rantapaa-Dahlqvist S; Martin J; Klareskog L; Padyukov L; Gregersen PK; Worthington J; Greenberg JD; Plenge RM; Bae S-C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(3):579-586

Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles

Wagner CA; Sokolove J; Lahey LJ; Bengtsson C; Saevarsdottir S; Alfredsson L; Delanoy M; Lindstrom TM; Walker RP; Bromberg R; Chandra PE; Binder SR; Klareskog L; Robinson WH
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):25

Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage

Brink M; Verheul MK; Ronnelid J; Berglin E; Holmdahl R; Toes REM; Klareskog L; Trouw LA; Rantapaa-Dahlqvist S
Article: ARTHRITIS & RHEUMATOLOGY. 2015;67(2):352-362

To What Extent Is the Familial Risk of Rheumatoid Arthritis Explained by Established Rheumatoid Arthritis Risk Factors?

Jiang X; Frisell T; Askling J; Karlson EW; Klareskog L; Alfredsson L; Kallberg H
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(2):375-380

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

Hensvold AH; Magnusson PKE; Joshua V; Hansson M; Israelsson L; Ferreira R; Jakobsson P-J; Holmdahl R; Hammarstrom L; Malmstrom V; Askling J; Klareskog L; Catrina AI
Article: PLOS ONE. 2015;10(4):e0122271

TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits

Diogo D; Bastarache L; Liao KP; Graham RR; Fulton RS; Greenberg JD; Eyre S; Bowes J; Cui J; Lee A; Pappas DA; Kremer JM; Barton A; Coenen MJH; Franke B; Kiemeney LA; Mariette X; Richard-Miceli C; Canhao H; Fonseca JE; de Vries N; Tak PP; Crusius JBA; Nurmohamed MT; Kurreeman F; Mikuls TR; Okada Y; Stahl EA; Larson DE; Deluca TL; O'Laughlin M; Fronick CC; Fulton LL; Kosoy R; Ransom M; Bhangale TR; Ortmann W; Cagan A; Gainer V; Karlson EW; Kohane I; Murphy SN; Martin J; Zhernakova A; Klareskog L; Padyukov L; Worthington J; Mardis ER; Seldin MF; Gregersen PK; Behrens T; Raychaudhuri S; Denny JC; Plenge RM
Article: CELL REPORTS. 2014;9(4):1417-1429

A Role for Noncoding Variation in Schizophrenia

Roussos P; Mitchell AC; Voloudakis G; Fullard JF; Pothula VM; Tsang J; Stahl EA; Georgakopoulos A; Ruderfer DM; Charney A; Okada Y; Siminovitch KA; Worthington J; Padyukov L; Klareskog L; Gregersen PK; Plenge RM; Raychaudhuri S; Fromer M; Purcell SM; Brennand KJ; Robakis NK; Schadt EE; Akbarian S; Sklar P
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(11):2029-2033

Overweight decreases the chance of achieving good response and low disease activity in early rheumatoid arthritis

Sandberg MEC; Bengtsson C; Kallberg H; Wesley A; Klareskog L; Alfredsson L; Saevarsdottir S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(10):1761-1768

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies

Jiang X; Trouw LA; van Wesemael TJ; Shi J; Bengtsson C; Kallberg H; Malmstrom V; Israelsson L; Hreggvidsdottir H; Verduijn W; Klareskog L; Alfredsson L; Huizinga TWJ; Toes REM; Lundberg K; van der Woude D
Article: ARTHRITIS CARE & RESEARCH. 2014;66(10):1582-1586

Smokeless Tobacco (Moist Snuff) Use and the Risk of Developing Rheumatoid Arthritis: Results From a Case-Control Study

Jiang X; Alfredsson L; Klareskog L; Bengtsson C
Article: MOLECULAR PSYCHIATRY. 2014;19(10):1085-1094

A genome-wide association study of anorexia nervosa

Boraska V; Franklin CS; Floyd JAB; Thornton LM; Huckins LM; Southam L; Rayner NW; Tachmazidou I; Klump KL; Treasure J; Lewis CM; Schmidt U; Tozzi F; Kiezebrink K; Hebebrand J; Gorwood P; Adan RAH; Kas MJH; Favaro A; Santonastaso P; Fernandez-Aranda F; Gratacos M; Rybakowski F; Dmitrzak-Weglarz M; Kaprio J; Keski-Rahkonen A; Raevuori A; Van Furth EF; 't Landt MCTS-O; Hudson JI; Reichborn-Kjennerud T; Knudsen GPS; Monteleone P; Kaplan AS; Karwautz A; Hakonarson H; Berrettini WH; Guo Y; Li D; Schork NJ; Komaki G; Ando T; Inoko H; Esko T; Fischer K; Maennik K; Metspalu A; Baker JH; Cone RD; Dackor J; DeSocio JE; Hilliard CE; O'Toole JK; Pantel J; Szatkiewicz JP; Taico C; Zerwas S; Trace SE; Davis OSP; Helder S; Buehren K; Burghardt R; de Zwaan M; Egberts K; Ehrlich S; Herpertz-Dahlmann B; Herzog W; Imgart H; Scherag A; Scherag S; Zipfel S; Boni C; Ramoz N; Versini A; Brandys MK; Danner UN; de Kovel C; Hendriks J; Koeleman BPC; Ophoff RA; Strengman E; van Elburg AA; Bruson A; Clementi M; Degortes D; Forzan M; Tenconi E; Docampo E; Escaramis G; Jimenez-Murcia S; Lissowska J; Rajewski A; Szeszenia-Dabrowska N; Slopien A; Hauser J; Karhunen L; Meulenbelt I; Slagboom PE; Tortorella A; Maj M; Dedoussis G; Dikeos D; Gonidakis F; Tziouvas K; Tsitsika A; Papezova H; Slachtova L; Martaskova D; Kennedy JL; Levitan RD; Yilmaz Z; Huemer J; Koubek D; Merl E; Wagner G; Lichtenstein P; Breen G; Cohen-Woods S; Farmer A; McGuffin P; Cichon S; Giegling I; Herms S; Rujescu D; Schreiber S; Wichmann H-E; Dina C; Sladek R; Gambaro G; Soranzo N; Julia A; Marsal S; Rabionet R; Gaborieau V; Dick DM; Palotie A; Ripatti S; Widen E; Andreassen OA; Espeseth T; Lundervold A; Reinvang I; Steen VM; Le Hellard S; Mattingsdal M; Ntalla I; Bencko V; Foretova L; Janout V; Navratilova M; Gallinger S; Pinto D; Scherer SW; Aschauer H; Carlberg L; Schosser A; Alfredsson L; Ding B; Klareskog L; Padyukov L; Courtet P; Guillaume S; Jaussent I; Finan C; Kalsi G; Roberts M; Logan DW; Peltonen L; Ritchie GRS; Barrett JC; Estivill X; Hinney A; Sullivan PF; Collier DA; Zeggini E; Bulik CM
Article: ARTHRITIS RESEARCH & THERAPY. 2014;16(4):414

Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis

Snir O; Gomez-Cabrero D; Montes A; Perez-Pampin E; Gomez-Reino JJ; Seddighzadeh M; Klich KU; Israelsson L; Ding B; Catrina AI; Holmdahl R; Alfredsson L; Klareskog L; Tegner J; Gonzalez A; Malmstrom V; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2014;16(4):R167

Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint

Ossipova E; Cerqueira CF; Reed E; Kharlamova N; Israelsson L; Holmdahl R; Nandakumar KS; Engstrom M; Harre U; Schett G; Catrina AI; Malmstrom V; Sommarin Y; Klareskog L; Jakobsson P-J; Lundberg K
Article: HUMAN MOLECULAR GENETICS. 2014;23(15):4177-4184

IgA measurements in over 12 000 Swedish twins reveal sex differential heritability and regulatory locus near CD30L

Viktorin A; Frankowiack M; Padyukov L; Chang Z; Melen E; Saaf A; Kull I; Klareskog L; Hammarstrom L; Magnusson PKE
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(8):1541-1544

Patients with regular physical activity before onset of rheumatoid arthritis present with milder disease

Sandberg MEC; Wedren S; Klareskog L; Lundberg IE; Opava CH; Alfredsson L; Saevarsdottir S
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(7):1712-1722

Citrulline-Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy

James EA; Rieck M; Pieper J; Gebe JA; Yue BB; Tatum M; Peda M; Sandin C; Klareskog L; Malmstrom V; Buckner JH
Article: JOURNAL OF INTERNAL MEDICINE. 2014;275(6):640-651

The HLA locus contains novel foetal susceptibility alleles for congenital heart block with significant paternal influence

Meisgen S; Ostberg T; Salomonsson S; Ding B; Eliasson H; Malarstig A; Alfredsson L; Klareskog L; Hamsten A; Olsson T; Axelsson T; Gadler F; Jonzon A; Sonesson S-E; Kockum I; Wahren-Herlenius M
Article: ARTHRITIS CARE & RESEARCH. 2014;66(6):844-851

Association Between Life Events and Rheumatoid Arthritis: Results From a Population-Based Case-Control Study

Wesley A; Bengtsson C; Skillgate E; Saevarsdottir S; Theorell T; Holmqvist M; Klareskog L; Alfredsson L; Wedren S
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2014;94(4):522-532

Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity

Han B; Diogo D; Eyre S; Kallberg H; Zhernakova A; Bowes J; Padyukov L; Okada Y; Gonzalez-Gay MA; Rantapaa-Dahlqvist S; Martin J; Huizinga TWJ; Plenge RM; Worthington J; Gregersen PK; Klareskog L; de Bakker PIW; Raychaudhuri S
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2014;94(4):485-495

GeMes, Clusters of DNA Methylation under Genetic Control, Can Inform Genetic and Epigenetic Analysis of Disease

Liu Y; Li X; Aryee MJ; Ekstrom TJ; Padyukov L; Klareskog L; Vandiver A; Moore AZ; Tanaka T; Ferrucci L; Fallin MD; Feinberg AP
Article: MODERN RHEUMATOLOGY. 2014;24(2):271-274

Silica exposure is associated with an increased risk of developing ACPA-positive rheumatoid arthritis in an Asian population: evidence from the Malaysian MyEIRA case-control study

Yahya A; Bengtsson C; Larsson P; Too CL; Mustafa AN; Abdullah NA; Muhamad NA; Klareskog L; Murad S; Alfredsson L
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(3):513-522

Features of the Synovium of Individuals at Risk of Developing Rheumatoid Arthritis

de Hair MJH; van de Sande MGH; Ramwadhdoebe TH; Hansson M; Landewe R; van der Leij C; Maas M; Serre G; van Schaardenburg D; Klareskog L; Gerlag DM; van Baarsen LGM; Tak PP
Article: GENES AND IMMUNITY. 2014;15(2):107-114

The influence of polygenic risk scores on heritability of anti-CCP level in RA

Cui J; Taylor KE; Lee YC; Kallberg H; Weinblatt ME; Coblyn JS; Klareskog L; Criswell LA; Gregersen PK; Shadick NA; Plenge RM; Karlson EW
Article: NATURE. 2014;506(7488):376-381

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Okada Y; Wu D; Trynka G; Raj T; Terao C; Ikari K; Kochi Y; Ohmura K; Suzuki A; Yoshida S; Graham RR; Manoharan A; Ortmann W; Bhangale T; Denny JC; Carroll RJ; Eyler AE; Greenberg JD; Kremer JM; Pappas DA; Jiang L; Yin J; Ye L; Su D-F; Yang J; Xie G; Keystone E; Westra H-J; Esko T; Metspalu A; Zhou X; Gupta N; Mirel D; Stahl EA; Diogo D; Cui J; Liao K; Guo MH; Myouzen K; Kawaguchi T; Coenen MJH; van Riel PLCM; van de laar MAFJ; Guchelaar H-J; Huizinga TWJ; Dieude P; Mariette X; Bridges SLJ; Zhernakova A; Toes REM; Tak PP; Miceli-Richard C; Bang S-Y; Lee H-S; Martin J; Gonzalez-Gay MA; Rodriguez-Rodriguez L; Rantapaa-Dahlqvist S; Arlestig L; Choi HK; Kamatani Y; Galan P; Lathrop M; Eyre S; Bowes J; Barton A; de Vries N; Moreland LW; Criswell LA; Karlson EW; Taniguchi A; Yamada R; Kubo M; Liu JS; Bae S-C; Worthington J; Padyukov L; Klareskog L; Gregersen PK; Raychaudhuri S; Stranger BE; De Jager PL; Franke L; Visscher PM; Brown MA; Yamanaka H; Mimori T; Takahashi A; Xu H; Behrens TW; Siminovitch KA; Momohara S; Matsuda F; Yamamoto K; Plenge RM
Article: PLOS ONE. 2014;9(9):e104382

Accelerating Translational Research by Clinically Driven Development of an Informatics Platform-A Case Study

Abugessaisa I; Saevarsdottir S; Tsipras G; Lindblad S; Sandin C; Nikamo P; Stahle M; Malmstrom V; Klareskog L; Tegner J
Article: PLOS ONE. 2014;9(2):e87645

Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene

Okada Y; Diogo D; Greenberg JD; Mouassess F; Achkar WAL; Fulton RS; Denny JC; Gupta N; Mirel D; Gabriel S; Li G; Kremer JM; Pappas DA; Carroll RJ; Eyler AE; Trynka G; Stahl EA; Cui J; Saxena R; Coenen MJH; Guchelaar H-J; Huizinga TWJ; Dieude P; Mariette X; Barton A; Canhao H; Fonseca JE; de Vries N; Tak PP; Moreland LW; Bridges SLJ; Miceli-Richard C; Choi HK; Kamatani Y; Galan P; Lathrop M; Raj T; De Jager PL; Raychaudhuri S; Worthington J; Padyukov L; Klareskog L; Siminovitch KA; Gregersen PK; Mardis ER; Arayssi T; Kazkaz LA; Plenge RM
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(1):31-39

Structural Changes and Antibody Enrichment in the Lungs Are Early Features of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis

Reynisdottir G; Karimi R; Joshua V; Olsen H; Hensvold AH; Harju A; Engstrom M; Grunewald J; Nyren S; Eklund A; Klareskog L; Skold CM; Catrina AI
Article: PLOS ONE. 2014;9(11):e113924

IgG Antibodies to Cyclic Citrullinated Peptides Exhibit Profiles Specific in Terms of IgG Subclasses, Fc-Glycans and a Fab-Peptide Sequence

Lundstrom SL; Fernandes-Cerqueira C; Ytterberg AJ; Ossipova E; Hensvold AH; Jakobsson P-J; Malmstrom V; Catrina AI; Klareskog L; Lundberg K; Zubarev RA
Article: ARTHRITIS & RHEUMATOLOGY. 2013;65(12):3058-3062

Identification of BACH2 and RAD51B as Rheumatoid Arthritis Susceptibility Loci in a Meta-Analysis of Genome-Wide Data

McAllister K; Yarwood A; Bowes J; Orozco G; Viatte S; Diogo D; Hocking LJ; Steer S; Wordsworth P; Wilson AG; Morgan AW; Kremer JM; Pappas D; Gregersen P; Klareskog L; Plenge R; Barton A; Greenberg J; Worthington J; Eyre S
Article: ARTHRITIS & RHEUMATOLOGY. 2013;65(11):2773-2782

Familial Risks and Heritability of Rheumatoid Arthritis Role of Rheumatoid Factor/Anti-Citrullinated Protein Antibody Status, Number and Type of Affected Relatives, Sex, and Age

Frisell T; Holmqvist M; Kallberg H; Klareskog L; Alfredsson L; Askling J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(8):1287-1294

Impact of intravenous abatacept on synovitis, osteitis and structural damage in patients with rheumatoid arthritis and an inadequate response to methotrexate: the ASSET randomised controlled trial

Conaghan PG; Durez P; Alten RE; Burmester G-R; Tak PP; Klareskog L; Catrina AI; DiCarlo J; Gaillez C; Le Bars M; Zhou X; Peterfy C
Article: ARTHRITIS & RHEUMATOLOGY. 2013;65(7):1702-1712

Autoantibodies to Posttranslationally Modified Type II Collagen as Potential Biomarkers for Rheumatoid Arthritis

Strollo R; Ponchel F; Malmstrom V; Rizzo P; Bombardieri M; Wenham CY; Landy R; Perret D; Watt F; Corrigall VM; Winyard PG; Pozzilli P; Conaghan PG; Panayi GS; Klareskog L; Emery P; Nissim A
Article: ARTHRITIS CARE & RESEARCH. 2013;65(7):1147-1156

Association of Environmental and Genetic Factors and Gene-Environment Interactions With Risk of Developing Rheumatoid Arthritis

Karlson EW; Ding B; Keenan BT; Liao K; Costenbader KH; Klareskog L; Alfredsson L; Chibnik LB
Article: ARTHRITIS CARE & RESEARCH. 2013;65(7):1190-1196

Ambient Air Pollution Exposures and Risk of Rheumatoid Arthritis

Hart JE; Kaellberg H; Laden F; Costenbader KH; Yanosky JD; Klareskog L; Alfredsson L; Karlson EW
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(6):1018-1025

HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

Lundstrom E; Gustafsson JT; Jonsen A; Leonard D; Zickert A; Elvin K; Sturfelt G; Nordmark G; Bengtsson AA; Sundin U; Kallberg H; Sandling JK; Syvanen A-C; Klareskog L; Gunnarsson I; Ronnblom L; Padyukov L; Svenungsson E
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(6):888-894

Ambient air pollution exposures and risk of rheumatoid arthritis: results from the Swedish EIRA case-control study

Hart JE; Kaellberg H; Laden F; Bellander T; Costenbader KH; Holmqvist M; Klareskog L; Alfredsson L; Karlson EW
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(5):652-658

Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile

Lundberg K; Bengtsson C; Kharlamova N; Reed E; Jiang X; Kallberg H; Pollak-Dorocic I; Israelsson L; Kessel C; Padyukov L; Holmdahl R; Alfredsson L; Klareskog L
Article: MODERN RHEUMATOLOGY. 2013;:1-5

Silica exposure is associated with an increased risk of developing ACPA-positive rheumatoid arthritis in an Asian population: evidence from the Malaysian MyEIRA case-control study.

Yahya A; Bengtsson C; Larsson P; Too CL; Mustafa AN; Abdullah NA; Muhamad NA; Klareskog L; Murad S; Alfredsson L
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2013;11:85

Implementation of the CDC translational informatics platform - from genetic variants to the national Swedish Rheumatology Quality Register

Abugessaisa I; Gomez-Cabrero D; Snir O; Lindblad S; Klareskog L; Malmstrom V; Tegner J
Article: ARTHRITIS & RHEUMATOLOGY. 2013;65(4):899-910

Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis

Brink M; Hansson M; Mathsson L; Jakobsson P-J; Holmdahl R; Hallmans G; Stenlund H; Ronnelid J; Klareskog L; Rantapaa-Dahlqvist S
Article: GENES AND IMMUNITY. 2013;14(2):83-89

Genetic variation in the serotonin receptor gene affects immune responses in rheumatoid arthritis

Snir O; Hesselberg E; Amoudruz P; Klareskog L; Zarea-Ganji I; Catrina A; Padyukov L; Malmstrom V; Seddighzadeh M
Article: NATURE BIOTECHNOLOGY. 2013;31(2):142-147

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

Liu Y; Aryee MJ; Padyukov L; Fallin MD; Hesselberg E; Runarsson A; Reinius L; Acevedo N; Taub M; Ronninger M; Shchetynsky K; Scheynius A; Kere J; Alfredsson L; Klareskog L; Ekstrom TJ; Feinberg AP
Article: TWIN RESEARCH AND HUMAN GENETICS. 2013;16(1):317-329

The Swedish Twin Registry: Establishment of a Biobank and Other Recent Developments

Magnusson PKE; Almqvist C; Rahman I; Ganna A; Viktorin A; Walum H; Halldner L; Lundstrom S; Ullen F; Langstrom N; Larsson H; Nyman A; Gumpert CH; Rastam M; Anckarsater H; Cnattingius S; Johannesson M; Ingelsson E; Klareskog L; de Faire U; Pedersen NL; Lichtenstein P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2013;92(1):15-27

Rare, Low-Frequency, and Common Variants in the Protein-Coding Sequence of Biological Candidate Genes from GWASs Contribute to Risk of Rheumatoid Arthritis

Diogo D; Kurreeman F; Stahl EA; Liao KP; Gupta N; Greenberg JD; Rivas MA; Hickey B; Flannick J; Thomson B; Guiducci C; Ripke S; Adzhubey I; Barton A; Kremer JM; Alfredsson L; Sunyaev S; Martin J; Zhernakova A; Bowes J; Eyre S; Siminovitch KA; Gregersen PK; Worthington J; Klareskog L; Padyukov L; Raychaudhuri S; Plenge RM
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2013;42(5):337-343

Regional differences regarding risk of developing rheumatoid arthritis in Stockholm County, Sweden: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study

Kallberg H; Vieira V; Holmqvist M; Hart JE; Costenbader KH; Bengtsson C; Klareskog L; Karlson EW; Alfredsson L
Article: PLOS GENETICS. 2013;9(12):e1003993

Quantifying Missing Heritability at Known GWAS Loci

Gusev A; Bhatia G; Zaitlen N; Vilhjalmsson BJ; Diogo D; Stahl EA; Gregersen PK; Worthington J; Klareskog L; Raychaudhuri S; Plenge RM; Pasaniuc B; Price AL
Article: PLOS ONE. 2013;8(6):e66456

Identification of the Tyrosine-Protein Phosphatase Non-Receptor Type 2 as a Rheumatoid Arthritis Susceptibility Locus in Europeans

Cobb JE; Plant D; Flynn E; Tadjeddine M; Dieude P; Cornelis F; Arlestig L; Dahlqvist SR; Goulielmos G; Boumpas DT; Sidiropoulos P; Krintel SB; Ornbjerg LM; Hetland ML; Klareskog L; Haeupl T; Filer A; Buckley CD; Raza K; Witte T; Schmidt RE; FitzGerald O; Veale D; Eyre S; Worthington J
Article: ARTHRITIS CARE & RESEARCH. 2013;65(1):107-112

Association between body mass index and anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis: Results from a population-based case-control study

Wesley A; Bengtsson C; Elkan A-C; Klareskog L; Alfredsson L; Wedren S
Article: NATURE GENETICS. 2012;44(12):1336-1340

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

Eyre S; Bowes J; Diogo D; Lee A; Barton A; Martin P; Zhernakova A; Stahl E; Viatte S; McAllister K; Amos CI; Padyukov L; Toes REM; Huizinga TWJ; Wijmenga C; Trynka G; Franke L; Westra H-J; Alfredsson L; Hu X; Sandor C; de Bakker PIW; Davila S; Khor CC; Heng KK; Andrews R; Edkins S; Hunt SE; Langford C; Symmons D; Concannon P; Onengut-Gumuscu S; Rich SS; Deloukas P; Gonzalez-Gay MA; Rodriguez-Rodriguez L; Arlsetig L; Martin J; Rantapaa-Dahlqvist S; Plenge RM; Raychaudhuri S; Klareskog L; Gregersen PK; Worthington J
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(6):R250

Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis

Too CL; Murad S; Dhaliwal JS; Larsson P; Jiang X; Ding B; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(5):R201

Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides

Hansson M; Mathsson L; Schlederer T; Israelsson L; Matsson P; Nogueira L; Jakobsson P-J; Lundberg K; Malmstrom V; Serre G; Holmdahl R; Nystrand M; Klareskog L; Ronnelid J
Article: ARTHRITIS & RHEUMATOLOGY. 2012;64(8):2482-2488

Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis

Snir O; Backlund J; Bostrom J; Andersson I; Kihlberg J; Buckner JH; Klareskog L; Holmdahl R; Malmstrom V
Article: MODERN RHEUMATOLOGY. 2012;22(4):524-531

Smoking is associated with an increased risk of developing ACPA-positive but not ACPA-negative rheumatoid arthritis in Asian populations: evidence from the Malaysian MyEIRA case-control study

Yahya A; Bengtsson C; Lai TC; Larsson PT; Mustafa AN; Abdullah NA; Muhamad N; Hussein H; Klareskog L; Alfredsson L; Murad S
Article: JOURNAL OF RHEUMATOLOGY. 2012;39(8):1509-1516

Variants Within STAT Genes Reveal Association with Anticitrullinated Protein Antibody-negative Rheumatoid Arthritis in 2 European Populations

Seddighzadeh M; Gonzalez A; Ding B; Ferreiro-Iglesias A; Gomez-Reino JJ; Klareskog L; Alfredsson L; Dunussi-Joannopoulos K; Clark JD; Padyukov L
Article: ARTHRITIS & RHEUMATOLOGY. 2012;64(7):2078-2084

Very high levels of anti-citrullinated protein antibodies are associated with HLA-DRB1*15 non-shared epitope allele in patients with rheumatoid arthritis

Laki J; Lundstrom E; Snir O; Ronnelid J; Ganji I; Catrina AI; Bengtsson C; Saevarsdottir S; Wick MC; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(3):R100

Anti-type II collagen antibodies are associated with early radiographic destruction in rheumatoid arthritis

Mullazehi M; Wick MC; Klareskog L; van Vollenhoven R; Ronnelid J
Article: JOURNAL OF CLINICAL INVESTIGATION. 2012;122(5):1791-1802

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

Harre U; Georgess D; Bang H; Bozec A; Axmann R; Ossipova E; Jakobsson P-J; Baum W; Nimmerjahn F; Szarka E; Sarmay G; Krumbholz G; Neumann E; Toes R; Scherer H-U; Catrina AI; Klareskog L; Jurdic P; Schett G
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(2):R89

Smoking interacts with HLA-DRB1 shared epitope in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis: results from the Malaysian Epidemiological Investigation of Rheumatoid Arthritis (MyEIRA)

Too CL; Yahya A; Murad S; Dhaliwal JS; Larsson PT; Muhamad NA; Abdullah NA; Mustafa AN; Klareskog L; Alfredsson L; Padyukov L; Bengtsson C
Article: ARTHRITIS RESEARCH & THERAPY. 2012;14(1):R41

Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study

Sverdrup BM; Kallberg H; Klareskog L; Alfredsson L
Article: NATURE GENETICS. 2012;44(3):291-296

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

Raychaudhuri S; Sandor C; Stahl EA; Freudenberg J; Lee H-S; Jia X; Alfredsson L; Padyukov L; Klareskog L; Worthington J; Siminovitch KA; Bae S-C; Plenge RM; Gregersen PK; de Bakker PIW
Article: PHARMACOGENETICS AND GENOMICS. 2012;22(1):1-9

Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis

Dervieux T; Wessels JAM; Kremer JM; Padyukov L; Seddighzadeh M; Saevarsdottir S; van Vollenhoven RF; Klareskog L; Huizinga TW; Guchelaar H-J
Article: PLOS GENETICS. 2011;7(8):e1002254

Pervasive Sharing of Genetic Effects in Autoimmune Disease

Cotsapas C; Voight BF; Rossin E; Lage K; Neale BM; Wallace C; Abecasis GR; Barrett JC; Behrens T; Cho J; De Jager PL; Elder JT; Graham RR; Gregersen P; Klareskog L; Siminovitch KA; van Heel DA; Wijmenga C; Worthington J; Todd JA; Hafler DA; Rich SS; Daly MJ
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2011;19(8):908-914

Variants of gene for microsomal prostaglandin E2 synthase show association with disease and severe inflammation in rheumatoid arthritis

Korotkova M; Daha NA; Seddighzadeh M; Ding B; Catrina AI; Lindblad S; Huizinga TWJ; Toes REM; Alfredsson L; Klareskog L; Jakobsson P-J; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(8):1407-1414

Sick leave and disability pension before and after initiation of antirheumatic therapies in clinical practice

Neovius M; Simard JF; Klareskog L; Askling J
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2011;26(7):557-561

GEIRA: gene-environment and gene-gene interaction research application

Ding B; Kallberg H; Klareskog L; Padyukov L; Alfredsson L
Article: ARTHRITIS RESEARCH & THERAPY. 2011;13(2):R65

Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers

Saevarsdottir S; Ding B; Steinsson K; Grondal G; Valdimarsson H; Alfredsson L; Klareskog L; Padyukov L
Article: PLOS GENETICS. 2011;7(4):e1001378

GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma

Smedby KE; Foo JN; Skibola CF; Darabi H; Conde L; Hjalgrim H; Kumar V; Chang ET; Rothman N; Cerhan JR; Brooks-Wilson AR; Rehnberg E; Irwan ID; Ryder LP; Brown PN; Bracci PM; Agana L; Riby J; Cozen W; Davis S; Hartge P; Morton LM; Severson RK; Wang SS; Slager SL; Fredericksen ZS; Novak AJ; Kay NE; Habermann TM; Armstrong B; Kricker A; Milliken S; Purdue MP; Vajdic CM; Boyle P; Lan Q; Zahm SH; Zhang Y; Zheng T; Leach S; Spinelli JJ; Smith MT; Chanock SJ; Padyukov L; Alfredsson L; Klareskog L; Glimelius B; Melbye M; Liu ET; Adami H-O; Humphreys K; Liu J
Article: PLOS ONE. 2011;6(3):e17880

Effects of GSTM1 in Rheumatoid Arthritis; Results from the Swedish EIRA study

Lundstrom E; Hartshorne T; Li K; Lindblad S; Wick MC; Bengtsson C; Alfredsson L; Klareskog L; Padyukov L
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2011;29(2):238-247

Assessment of long-term safety and efficacy of etanercept in a 5-year extension study in patients with rheumatoid arthritis

Klareskog L; Gaubitz M; Rodriguez-Valverde V; Malaise M; Dougados M; Wajdula J
Article: JOURNAL OF RHEUMATOLOGY. 2011;38(3):446-449

The Functional Polymorphism 844 A>G in Fc_αRI (CD89) Does Not Contribute to Systemic Sclerosis or Rheumatoid Arthritis Susceptibility

Broen JCA; Coenen MJH; Rueda B; Witte T; Padyukov L; Klareskog L; Hesselstrand R; Wuttge DM; Simeon C; Ortego-Centeno N; Gonzalez-Gay MA; Pros A; Hunzelman N; Riemekasten G; Kreuter A; Vonk M; Scorza R; Beretta L; Airo P; van Riel PLCM; Kimberly R; Martin J; Edberg J; Radstake TRDJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):508-511

Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke

Kallberg H; Ding B; Padyukov L; Bengtsson C; Ronnelid J; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):423-427

Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials

van de Sande MGH; Gerlag DM; Lodde BM; van Baarsen LGM; Alivernini S; Codullo V; Felea I; Vieira-Sousa E; Fearon U; Reece R; Montecucco C; Veale DJ; Pitzalis C; Emery P; Klareskog L; McInnes IB; Tak PP
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(3):516-519

Generalisability of clinical registers used for drug safety and comparative effectiveness research: coverage of the Swedish Biologics Register

Neovius M; Simard JF; Sundstrom A; Jacobsson L; Geborek P; Saxne T; Feltelius N; Klareskog L; Askling J
Article: PLOS GENETICS. 2011;7(2):e1002004

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

Zhernakova A; Stahl EA; Trynka G; Raychaudhuri S; Festen EA; Franke L; Westra H-J; Fehrmann RSN; Kurreeman FAS; Thomson B; Gupta N; Romanos J; McManus R; Ryan AW; Turner G; Brouwer E; Posthumus MD; Remmers EF; Tucci F; Toes R; Grandone E; Mazzilli MC; Rybak A; Cukrowska B; Coenen MJH; Radstake TRDJ; van Riel PLCM; Li Y; de Bakker PIW; Gregersen PK; Worthington J; Siminovitch KA; Klareskog L; Huizinga TWJ; Wijmenga C; Plenge RM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(2):259-265

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis

Padyukov L; Seielstad M; Ong RTH; Ding B; Ronnelid J; Seddighzadeh M; Alfredsson L; Klareskog L
Article: PLOS ONE. 2011;6(8):e22547

The Genetic Structure of the Swedish Population

Humphreys K; Grankvist A; Leu M; Hall P; Liu J; Ripatti S; Rehnstroem K; Groop L; Klareskog L; Ding B; Gronberg H; Xu J; Pedersen NL; Lichtenstein P; Mattingsdal M; Andreassen OA; O'Dushlaine C; Purcell SM; Sklar P; Sullivan PF; Hultman CM; Palmgren J; Magnusson PKE
Article: RHEUMATOLOGY. 2011;50(1):204-213

Ten years with biologics: to whom do data on effectiveness and safety apply?

Simard JF; Arkema EV; Sundstrom A; Geborek P; Saxne T; Baecklund E; Coster L; Dackhammar C; Jacobsson L; Feltelius N; Lindblad S; Rantapaa-Dahlqvist S; Klareskog L; van Vollenhoven RF; Neovius M; Askling J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2011;40(1):8-15

Small-area variations in sales of TNF inhibitors in Sweden between 2000 and 2009

Neovius M; Sundstrom A; Simard JF; Wettermark B; Cars T; Feltelius N; Askling J; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2011;63(1):26-36

Patients With Early Rheumatoid Arthritis Who Smoke Are Less Likely to Respond to Treatment With Methotrexate and Tumor Necrosis Factor Inhibitors Observations From the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Register Cohorts

Saevarsdottir S; Wedren S; Seddighzadeh M; Bengtsson C; Wesley A; Lindblad S; Askling J; Alfredsson L; Klareskog L
Article: PLOS ONE. 2011;6(6):e21069

Shared Epitope Alleles Remain A Risk Factor for Anti-Citrullinated Proteins Antibody (ACPA) - Positive Rheumatoid Arthritis in Three Asian Ethnic Groups

Chun-Lai T; Padyukov L; Dhaliwal JS; Lundstrom E; Yahya A; Muhamad NA; Klareskog L; Alfredsson L; Larsson PT; Murad S
Article: PLOS ONE. 2010;5(12):e14326

Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome

Coenen MJH; Enevold C; Barrera P; Schijvenaars MMVAP; Toonen EJM; Scheffer H; Padyukov L; Kastbom A; Klareskog L; Barton A; Kievit W; Rood MJ; Jansen TL; Swinkels D; van Riel PLCM; Franke B; Bendtzen K; Radstake TRDJ
Article: JOURNAL OF INTERNAL MEDICINE. 2010;268(6):578-585

Rapid increase in myocardial infarction risk following diagnosis of rheumatoid arthritis amongst patients diagnosed between 1995 and 2006

Holmqvist ME; Wedren S; Jacobsson LTH; Klareskog L; Nyberg F; Rantapaa-Dahlqvist S; Alfredsson L; Askling J
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(11):3196-3210

Effect of Interactions of Glutathione S-Transferase T1, M1, and P1 and HMOX1 Gene Promoter Polymorphisms With Heavy Smoking on the Risk of Rheumatoid Arthritis

Keenan BT; Chibnik LB; Cui J; Ding B; Padyukov L; Kallberg H; Bengtsson C; Klareskog L; Alfredsson L; Karlson EW
Article: NATURE GENETICS. 2010;42(11):996-999

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis

Hueffmeier U; Uebe S; Ekici AB; Bowes J; Giardina E; Korendowych E; Juneblad K; Apel M; McManus R; Ho P; Bruce IN; Ryan AW; Behrens F; Lascorz J; Boehm B; Traupe H; Lohmann J; Gieger C; Wichmann H-E; Herold C; Steffens M; Klareskog L; Wienker TF; FitzGerald O; Alenius G-M; McHugh NJ; Novelli G; Burkhardt H; Barton A; Reis A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(10):1831-1833

Common vaccinations among adults do not increase the risk of developing rheumatoid arthritis: results from the Swedish EIRA study

Bengtsson C; Kapetanovic MC; Kallberg H; Sverdrup B; Nordmark B; Klareskog L; Alfredsson L
Article: NATURE GENETICS. 2010;42(9):777-U69

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

Ferreira RC; Pan-Hammarstrom Q; Graham RR; Gateva V; Fontan G; Lee AT; Ortmann W; Urcelay E; Fernandez-Arquero M; Nunez C; Jorgensen G; Ludviksson BR; Koskinen S; Haimila K; Clark HF; Klareskog L; Gregersen PK; Behrens TW; Hammarstrom L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(8):1548-1553

Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers

Plant D; Flynn E; Mbarek H; Dieude P; Cornelis F; Arlestig L; Dahlqvist SR; Goulielmos G; Boumpas DT; Sidiropoulos P; Johansen JS; Ornbjerg LM; Hetland ML; Klareskog L; Filer A; Buckley CD; Raza K; Witte T; Schmidt RE; Worthington J
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(7):1849-1861

Rheumatoid Arthritis Risk Allele PTPRC Is Also Associated With Response to Anti-Tumor Necrosis Factor α Therapy

Cui J; Saevarsdottir S; Thomson B; Padyukov L; van der Helm-van Mil AHM; Nititham J; Hughes LB; de Vries N; Raychaudhuri S; Alfredsson L; Askling J; Wedren S; Ding B; Guiducci C; Wolbink GJ; Crusius JBA; van der Horst-Bruinsma IE; Herenius M; Weinblatt ME; Shadick NA; Worthington J; Batliwalla F; Kern M; Morgan AW; Wilson AG; Isaacs JD; Hyrich K; Seldin MF; Moreland LW; Behrens TW; Allaart CF; Criswell LA; Huizinga TWJ; Tak PP; Bridges SLJ; Toes REM; Barton A; Klareskog L; Gregersen PK; Karlson EW; Plenge RM
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2010;18(7):821-826

Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis

Seddighzadeh M; Korotkova M; Kallberg H; Ding B; Daha N; Kurreeman FAS; Toes REM; Huizinga TW; Catrina AI; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(7):1870-1880

The Programmed Death 1/Programmed Death Ligand 1 Inhibitory Pathway Is Up-Regulated in Rheumatoid Synovium and Regulates Peripheral T Cell Responses in Human and Murine Arthritis

Raptopoulou AP; Bertsias G; Makrygiannakis D; Verginis P; Kritikos I; Tzardi M; Klareskog L; Catrina AI; Sidiropoulos P; Boumpas DT
Article: PLOS ONE. 2010;5(6):e11310

The Gene Expression Profile in the Synovium as a Predictor of the Clinical Response to Infliximab Treatment in Rheumatoid Arthritis

Lindberg J; Wijbrandts CA; van Baarsen LG; Nader G; Klareskog L; Catrina A; Thurlings R; Vervoordeldonk M; Lundeberg J; Tak PP
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(6):1077-1085

Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk

Karlson EW; Chibnik LB; Kraft P; Cui J; Keenan BT; Ding B; Raychaudhuri S; Klareskog L; Alfredsson L; Plenge RM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(6):1072-1076

Silica exposure among male current smokers is associated with a high risk of developing ACPA-positive rheumatoid arthritis

Stolt P; Yahya A; Bengtsson C; Kallberg H; Ronnelid J; Lundberg I; Klareskog L; Alfredsson L
Article: NATURE GENETICS. 2010;42(6):508-514

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

Stahl EA; Raychaudhuri S; Remmers EF; Xie G; Eyre S; Thomson BP; Li Y; Kurreeman FAS; Zhernakova A; Hinks A; Guiducci C; Chen R; Alfredsson L; Amos CI; Ardlie KG; Barton A; Bowes J; Brouwer E; Burtt NP; Catanese JJ; Coblyn J; Coenen MJH; Costenbader KH; Criswell LA; Crusius JBA; Cui J; de Bakker PIW; De Jager PL; Ding B; Emery P; Flynn E; Harrison P; Hocking LJ; Huizinga TWJ; Kastner DL; Ke X; Lee AT; Liu X; Martin P; Morgan AW; Padyukov L; Posthumus MD; Radstake TRDJ; Reid DM; Seielstad M; Seldin MF; Shadick NA; Steer S; Tak PP; Thomson W; van der Helm-van Mil AHM; van der Horst-Bruinsma IE; van der Schoot CE; van Riel PLCM; Weinblatt ME; Wilson AG; Wolbink GJ; Wordsworth BP; Wijmenga C; Karlson EW; Toes REM; de Vries N; Begovich AB; Worthington J; Siminovitch KA; Gregersen PK; Klareskog L; Plenge RM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(6):1129-1135

Golimumab in patients with active rheumatoid arthritis despite methotrexate therapy: 52-week results of the GO-FORWARD study

Keystone E; Genovese MC; Klareskog L; Hsia EC; Hall S; Miranda PC; Pazdur J; Bae S-C; Palmer W; Xu S; Rahman MU
Article: PROTEOMICS CLINICAL APPLICATIONS. 2010;4(5):511-518

MS analysis of rheumatoid arthritic synovial tissue identifies specific citrullination sites on fibrinogen

Hermansson M; Artemenko K; Ossipova E; Eriksson H; Lengqvist J; Makrygiannakis D; Catrina AI; Nicholas AP; Klareskog L; Savitski M; Zubarev RA; Jakobsson P-J
Article: NATURE GENETICS. 2010;42(5):426-429

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

Radstake TRDJ; Gorlova O; Rueda B; Martin J-E; Alizadeh BZ; Palomino-Morales R; Coenen MJ; Vonk MC; Voskuyl AE; Schuerwegh AJ; Broen JC; van Riel PLCM; van't Slot R; Italiaander A; Ophoff RA; Riemekasten G; Hunzelmann N; Simeon CP; Ortego-Centeno N; Gonzalez-Gay MA; Gonzalez-Escribano MF; Airo P; van Laar J; Herrick A; Worthington J; Hesselstrand R; Smith V; de Keyser F; Houssiau F; Chee MM; Madhok R; Shiels P; Westhovens R; Kreuter A; Kiener H; de Baere E; Witte T; Padykov L; Klareskog L; Beretta L; Scorza R; Lie BA; Hoffmann-Vold A-M; Carreira P; Varga J; Hinchcliff M; Gregersen PK; Lee AT; Ying J; Han Y; Weng S-F; Amos CI; Wigley FM; Hummers L; Nelson JL; Agarwal SK; Assassi S; Gourh P; Tan FK; Koeleman BPC; Arnett FC; Martin J; Mayes MD
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(5):1236-1245

Protection Against Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis Is Predominantly Associated With HLA-DRB1*1301 A Meta-Analysis of HLA-DRB1 Associations With Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis in Four European Populations

van der Woude D; Lie BA; Lundstrom E; Balsa A; Feitsma AL; Houwing-Duistermaat JJ; Verduijn W; Nordang GBN; Alfredsson L; Klareskog L; Pascual-Salcedo D; Gonzalez-Gay MA; Lopez-Nevot MA; Valero F; Roep BO; Huizinga TWJ; Kvien TK; Martin J; Padyukov L; de Vries RRP; Toes REM
Article: PLOS ONE. 2010;5(2):e9315

Analysis of Neuropeptide S Receptor Gene (NPSR1) Polymorphism in Rheumatoid Arthritis

D'Amato M; Zucchelli M; Seddighzadeh M; Anedda F; Lindblad S; Kere J; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS RESEARCH & THERAPY. 2010;12(6):R211

Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study

Visvanathan S; Rahman MU; Keystone E; Genovese M; Klareskog L; Hsia E; Mack M; Buchanan J; Elashoff M; Wagner C
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(1):44-52

Antibodies to Several Citrullinated Antigens Are Enriched in the Joints of Rheumatoid Arthritis Patients

Snir O; Widhe M; Hermansson M; von Spee C; Lindberg J; Hensen S; Lundberg K; Engstrom A; Venables PJW; Toes REM; Holmdahl R; Klareskog L; Malmstrom V
Article: SCIENCE TRANSLATIONAL MEDICINE. 2009;1(10):10ra21

A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

Jagodic M; Colacios C; Nohra R; Dejean AS; Beyeen AD; Khademi M; Casemayou A; Lamouroux L; Duthoit C; Papapietro O; Sjoholm L; Bernard I; Lagrange D; Dahlman I; Lundmark F; Oturai AB; Soendergaard HB; Kemppinen A; Saarela J; Tienari PJ; Harbo HF; Spurkland A; Ramagopalan SV; Sadovnick DA; Ebers GC; Seddighzadeh M; Klareskog L; Alfredsson L; Padyukov L; Hillert J; Clanet M; Edan G; Fontaine B; Fournie GJ; Kockum I; Saoudi A; Olsson T
Article: NATURE GENETICS. 2009;41(12):1313-1318

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

Raychaudhuri S; Thomson BP; Remmers EF; Eyre S; Hinks A; Guiducci C; Catanese JJ; Xie G; Stahl EA; Chen R; Alfredsson L; Amos CI; Ardlie KG; Barton A; Bowes J; Burtt NP; Chang M; Coblyn J; Costenbader KH; Criswell LA; Crusius JBA; Cui J; De Jager PL; Ding B; Emery P; Flynn E; Harrison P; Hocking LJ; Huizinga TWJ; Kastner DL; Ke X; Kurreeman FAS; Lee AT; Liu X; Li Y; Martin P; Morgan AW; Padyukov L; Reid DM; Seielstad M; Seldin MF; Shadick NA; Steer S; Tak PP; Thomson W; van der Helm-van Mil AHM; van der Horst-Bruinsma IE; Weinblatt ME; Wilson AG; Wolbink GJ; Wordsworth P; Altshuler D; Karlson EW; Toes REM; de Vries N; Begovich AB; Siminovitch KA; Worthington J; Klareskog L; Gregersen PK; Daly MJ; Plenge RM
Article: NATURE GENETICS. 2009;41(12):1319-1324

Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis

Mahdi H; Fisher BA; Kallberg H; Plant D; Malmstrom V; Ronnelid J; Charles P; Ding B; Alfredsson L; Padyukov L; Symmons DPM; Venables PJ; Klareskog L; Lundberg K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(44):18680-18685

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

Rioux JD; Goyette P; Vyse TJ; Hammarstroem L; Fernando MMA; Green T; De Jager PL; Foisy S; Wang J; de Bakker PIW; Leslie S; McVean G; Padyukov L; Alfredsson L; Annese V; Hafler DA; Pan-Hammarstroem Q; Matell R; Sawcer SJ; Compston AD; Cree BAC; Mirel DB; Daly MJ; Behrens TW; Klareskog L; Gregersen PK; Oksenberg JR; Hauser SL
Article: EPIDEMIOLOGY. 2009;20(6):896-901

Dietary Fish and Fish Oil and the Risk of Rheumatoid Arthritis

Rosell M; Wesley A-M; Rydin K; Klareskog L; Alfredsson L
Article: MOLECULAR MEDICINE. 2009;15(11-12):371-383

European Population Genetic Substructure: Further Definition of Ancestry Informative Markers for Distinguishing among Diverse European Ethnic Groups

Tian C; Kosoy R; Nassir R; Lee A; Villoslada P; Klareskog L; Hammarstrom L; Garchon H-J; Pulver AE; Ransom M; Gregersen PK; Seldin MF
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(11):3180-3189

Cancer Risk in Patients With Rheumatoid Arthritis Treated With Anti-Tumor Necrosis Factor α Therapies Does the Risk Change With the Time Since Start of Treatment?

Askling J; van Vollenhoven RF; Granath F; Raaschou P; Fored CM; Baecklund E; Dackhammar C; Feltelius N; Coster L; Geborek P; Jacobsson LT; Lindblad S; Rantapaa-Dahlqvist S; Saxne T; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(10):2861-2869

No Increased Occurrence of Ischemic Heart Disease Prior to the Onset of Rheumatoid Arthritis Results From Two Swedish Population-Based Rheumatoid Arthritis Cohorts

Holmqvist ME; Wedren S; Jacobsson LTH; Klareskog L; Nyberg F; Rantapaa-Dahlqvist S; Alfredsson L; Askling J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2009;613(1-3):155-162

Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice

Svelander L; Erlandsson-Harris H; Astner L; Grabowska U; Klareskog L; Lindstrom E; Hewitt E
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(6):789-796

Golimumab, a human antibody to tumour necrosis factor α given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study

Keystone EC; Genovese MC; Klareskog L; Hsia EC; Hall ST; Miranda PC; Pazdur J; Bae S-C; Palmer W; Zrubek J; Wiekowski M; Visvanathan S; Wu Z; Rahman MU
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(6):1597-1603

Gene-Environment Interaction Between the DRB1 Shared Epitope and Smoking in the Risk of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis

Lundstrom E; Kallberg H; Alfredsson L; Klareskog L; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(5):736-743

Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles

Snir O; Widhe M; von Spee C; Lindberg J; Padyukov L; Lundberg K; Engstrom A; Venables PJ; Lundeberg J; Holmdahl R; Klareskog L; Malmstrom V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(5):648-653

Anti-tumour necrosis factor therapy in rheumatoid arthritis and risk of malignant lymphomas: relative risks and time trends in the Swedish Biologics Register

Askling J; Baecklund E; Granath F; Geborek P; Fored M; Backlin C; Bertilsson L; Coster L; Jacobsson LT; Lindblad S; Lysholm J; Rantapaa-Dahlqvist S; Saxne T; van Vollenhoven R; Klareskog L; Feltelius N
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(5):1250-1254

The PRL-1149 G/T Polymorphism and Rheumatoid Arthritis Susceptibility

Lee YC; Raychaudhuri S; Cui J; De Vivo I; Ding B; Alfredsson L; Padyukov L; Costenbader KH; Selelstad M; Graham RR; Klareskog L; Gregersen PK; Plenge RM; Karlson EW
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(4):924-930

Opposing Effects of HLA-DRB1*13 Alleles on the Risk of Developing Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis

Lundstrom E; Kallberg H; Smolnikova M; Ding B; Ronnelid J; Alfredsson L; Klareskog L; Padyukov L
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(3):653-660

Specific Association of Type 1 Diabetes Mellitus With Anti-Cyclic Citrullinated Peptide-Positive Rheumatoid Arthritis

Liao KP; Gunnarsson M; Kallberg H; Ding B; Plenge RM; Padyukov L; Karlson EW; Klareskog L; Askling J; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(2):222-227

Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies

Kallberg H; Jacobsen S; Bengtsson C; Pedersen M; Padyukov L; Garred P; Frisch M; Karlson EW; Klareskog L; Alfredsson L
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(1):30-38

Different Patterns of Associations With Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis in the Extended Major Histocompatibility Complex Region

Ding B; Padyukov L; Lundstrom E; Seielstad M; Plenge RM; Oksenberg JR; Gregersen PK; Alfredsson L; Klareskog L
Article: ARTHRITIS RESEARCH & THERAPY. 2009;11(3):R81

Evaluation of arthroscopy and macroscopic scoring

Af Klint E; Catrina AI; Matt P; Neregrad P; Lampa J; Ulfgren A-K; Klareskog L; Lindblad S
Article: ARTHRITIS RESEARCH & THERAPY. 2009;11(3):R76

Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis

Hueber W; Tomooka BH; Batliwalla F; Li W; Monach PA; Tibshirani RJ; Van Vollenhoven RF; Lampa J; Saito K; Tanaka Y; Genovese MC; Klareskog L; Gregersen PK; Robinson WH
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2008;339(2):165-174

Serial re-challenge with influenza vaccine as a tool to study individual immune responses

Vallerskog T; Gaines H; Feldman A; Culbert E; Klareskog L; Malmstrom V; Trollmo C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(10):1444-1447

Improvements in clinical response between 12 and 24 weeks in patients with rheumatoid arthritis on etanercept therapy with or without methotrexate

Kavanaugh A; Klareskog L; van der Heijde D; Li J; Freundlich B; Hooper M
Article: NATURE GENETICS. 2008;40(10):1216-1223

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

Raychaudhuri S; Remmers EF; Lee AT; Hackett R; Guiducci C; Burtt NP; Gianniny L; Korman BD; Padyukov L; Kurreeman FAS; Chang M; Catanese JJ; Ding B; Wong S; Mil AHMVDH-V; Neale BM; Coblyn J; Cui J; Tak PP; Wolbink GJ; Crusius JBA; van der Horst-Bruinsma IE; Criswell LA; Amos CI; Seldin MF; Kastner DL; Ardlie KG; Alfredsson L; Costenbader KH; Altshuler D; Huizinga TWJ; Shadick NA; Weinblatt ME; de Vries N; Worthington J; Seielstad M; Toes REM; Karlson EW; Begovich AB; Klareskog L; Gregersen PK; Daly MJ; Plenge RM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(10):1488-1492

Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

Makrygiannakis D; Hermansson M; Ulfgren A-K; Nicholas AP; Zendman AJW; Eklund A; Grunewald J; Skold CM; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(9):1267-1270

Level of radiographic damage and radiographic progression are determinants of physical function: a longitudinal analysis of the TEMPO trial

van der Heijde D; Landewe R; van Vollenhoven R; Fatenejad S; Klareskog L
Article: CLINICAL IMMUNOLOGY. 2008;128(3):374-381

Identification of CTLA-4 isoforms produced by alternative splicing and their association with myasthenia gravis

Gu M; Kakoulidou M; Giscombe R; Pirskanen R; Lefvert AK; Klareskog L; Wang X
Article: ARTHRITIS & RHEUMATOLOGY. 2008;58(7):1931-1939

Modulation of CCR2 in rheumatoid arthritis - A double-blind, randomized, placebo-controlled clinical trial

Vergunst CE; Gerlag DM; Lopatinskaya L; Klareskog L; Smith MD; van den Bosch F; Dinant HJ; Lee Y; Wyant T; Jacobson EW; Baeten D; Tak PP
Article: GENES AND IMMUNITY. 2008;9(5):412-418

Differential expression of transcripts for the autoimmunity-related human dendritic cell immunoreceptor

Ronninger M; Eklow C; Lorentzen JC; Klareskog L; Padyukov L
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;141(1):69-72

Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis

Baecklund E; Natkunam Y; Backlin C; Iliadou A; Askling J; Ekbom A; Feltelius N; Klareskog L; Enblad G; Lossos IS; Levy R; Sundstroem C; Rosenquist R
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(3):330-334

Treatment of refractory SLE with rituximab plus cyclophosphamide:: clinical effects, serological changes, and predictors of response

Jonsdottir T; Gunnarsson I; Risselada A; Henriksson EW; Klareskog L; van Vollenhoven RF
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;152(1):192-199

Suppressive effects of a quinoxaline-analogue (Rob 803) on pathogenic immune mechanisms in collagen-induced arthritis

Westman E; Ngoc DDT; Klareskog L; Harris HE
Article: PLOS GENETICS. 2008;4(1):e4

Analysis and application of European genetic substructure using 300 KSNP information

Tian C; Plenge RM; Ransom M; Lee A; Villoslada P; Selmi C; Klareskog L; Pulver AE; Qi L; Gregersen PK; Seldin MF
Article: ARTHRITIS & RHEUMATOLOGY. 2008;58(1):36-45

Antibodies against citrullinated vimentin in rheumatoid arthritis

Mathsson L; Mullazehi M; Wick MC; Sjoberg O; van Vollenhoven R; Klareskog L; Ronnelid J
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(12):3928-3939

Disease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritis

van der Heijde D; Klareskog L; Landewe R; Bruyn GAW; Cantagrel A; Durez P; Herrero-Beaumont G; Molad Y; Codreanu C; Valentini G; Zahora R; Pedersen R; MacPeek D; Wajdula J; Fatenejad S
Article: NATURE GENETICS. 2007;39(12):1477-1482

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis

Plenge RM; Cotsapas C; Davies L; Price AL; Bakker PIW; Maller J; Pe'er I; Burtt NP; Blumenstiel B; DeFelice M; Parkin M; Barry R; Winslow W; Healy C; Graham RR; Neale BM; Izmailova E; Roubenoff R; Parker AN; Glass R; Karlson EW; Maher N; Hafler DA; Lee DM; Seldin MF; Remmers EF; Lee AT; Padyukov L; Alfredsson L; Coblyn J; Weinblatt ME; Gabriel SB; Purcell S; Klareskog L; Gregersen PK; Shadick NA; Daly MJ; Altshuler D
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2007;36(6):418-423

Infliximab dosage and infusion frequency in clinical practice: experiences in the Stockholm biologics registry STURE

van Vollenhoven RF; Klareskog L
Article: BLOOD. 2007;110(7):2484-2493

Natural killer cells trigger differentiation of monocytes into dendritic cells

Zhang AL; Colmenero P; Purath U; de Matos CT; Hueber W; Klareskog L; Tarner IH; Engleman EG; Soderstrom K
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(10):1339-1344

Time-dependent increase in risk of hospitalisation with infection among Swedish RA patients treated with TNF antagonists

Askling J; Fored CM; Brandt L; Baecklund E; Bertilsson L; Feltelius N; Coster L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapaa-Dahlqvist S; Saxne T; van Vollenhoven RF; Klareskog L
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2007;357(12):1199-1209

TRAF1-C5 as a risk locus for rheumatoid arthritis - A genomewide study

Plenge RM; Seielstad M; Padyukov L; Lee AT; Remmers EF; Ding B; Liew A; Khalili H; Chandrasekaran A; Davies LRL; Li W; Tan AKS; Bonnard C; Ong RTH; Thalamuthu A; Pettersson S; Liu C; Tian C; Chen WV; Carulli JP; Beckman EM; Altshuler D; Alfredsson L; Criswell LA; Amos CI; Seldin MF; Kastner DL; Klareskog L; Gregersen PK
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2007;357(10):977-986

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

Remmers EF; Plenge RM; Lee AT; Graham RR; Hom G; Behrens TW; de Bakker PIW; Le JM; Lee H-S; Batliwalla F; Li W; Masters SL; Booty MG; Carulli JP; Padyukov L; Alfredsson L; Klareskog L; Chen WV; Amos CI; Criswell LA; Seldin MF; Kastner DL; Gregersen PK
Article: PLOS MEDICINE. 2007;4(9):e278-1524

A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis

Kurreeman FAS; Padyukov L; Marques RB; Schrodi SJ; Seddighzadeh M; Stoeken-Rijsbergen G; van der Helm-van Mil AHM; Allaart CF; Verduyn W; Houwing-Duistermaat J; Alfredsson L; Begovich AB; Klareskog L; Huizinga TWJ; Toes REM
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2007;36(5):351-358

Randomized withdrawal of long-term prednisolone treatment in rheumatoid arthritis:: Effects on inflammation and bone mineral density

Tengstrand B; Larsson E; Klareskog L; Hafstroem I
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(8):2620-2632

Association of arthritis with a gene complex encoding C-type lectin-like receptors

Lorentzen JC; Flornes L; Eklow C; Backdahl L; Ribbhammar U; Guo JP; Smolnikova M; Dissen E; Seddighzadeh M; Brookes AJ; Alfredsson L; Klareskog L; Padyukov L; Fossum S
Article: ARTHRITIS & RHEUMATOLOGY. 2007;56(7):2202-2210

Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

Sigurdsson S; Padyukov L; Kurreeman FAS; Liljedahl U; Wiman A-C; Alfredsson L; Toes R; Ronnelid J; Klareskog L; Huizinga TWJ; Alm G; Syvanen A-C; Ronnblom L
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2007;80(5):867-875

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis

Kallberg H; Padyukov L; Plenge RM; Ronnelid J; Gregersen PK; van der Helm-van Mil AHM; Toes REM; Huizinga TW; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(4):481-485

Sulphasalazine inhibits human antigen-specific immune responses in vivo

Trollmo C; Gudmundsson S; Feltelius N; Rogberg S; Smedegard G; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(3):414-416

The inflammatory reflex and risk for rheumatoid arthritis: a case-control study of human vagotomy

Carlens C; Brandt L; Klareskog L; Lampa J; Askling J
Article: ARTHRITIS RESEARCH & THERAPY. 2007;9(5):r98

A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity

Olsson LM; Lindqvist A-K; Kallberg H; Padyukov L; Burkhardt H; Alfredsson L; Klareskog L; Holmdahl R
Article: CLINICAL IMMUNOLOGY. 2007;122(1):62-74

Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE

Vallerskog T; Gunnarsson I; Widhe M; Risselada A; Klareskog L; van Vollenhoven R; Malmstrom V; Trollmo C
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(12):3774-3781

Characteristics of diffuse large B cell lymphomas in rheumatoid arthritis

Baecklund E; Backlin C; Iliadou A; Granath F; Ekbom A; Amini R-M; Feltelius N; Enblad G; Sundstrom C; Klareskog L; Askling J; Rosenquist R
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(12):1578-1584

A long-term, open-label trial of the safety and efficacy of etanercept (Enbrel) in patients with rheumatoid arthritis not treated with other disease-modifying antirheumatic drugs

Klareskog L; Gaubitz M; Rodriguez-Valverde V; Malaise M; Dougados M; Wajdula J
Article: TWIN RESEARCH AND HUMAN GENETICS. 2006;9(6):875-882

The Swedish Twin Registry in the third millennium:: An update

Lichtenstein P; Sullivan PF; Cnattingius S; Gatz M; Johansson S; Carlstrom E; Bjork C; Svartengren M; Wolk A; Klareskog L; de Faire U; Schalling M; Palmgren J; Pedersen NL
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(10):3119-3125

Disconnect between inflammation and joint destruction after treatment with etanercept plus methotrexate -: Results from the trial of etanercept and methotrexate with radiographic and patient outcomes

Landewe R; van der Heijde D; Klareskog L; van Vollenhoven R; Fatenejad S
Article: PLOS GENETICS. 2006;2(9):e143-1351

European population substructure: Clustering of northern and southern populations

Seldin MF; Shigeta R; Villoslada P; Selmi C; Tuomilehto J; Silva G; Belmont JW; Klareskog L; Gregersen PK
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(9):1219-1222

Citrullination is an inflammation-dependent process

Makrygiannakis D; af Klint E; Lundberg IE; Lofberg R; Ulfgren A-K; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(9):1184-1187

Risk for malignant lymphoma in ankylosing spondylitis: a nationwide Swedish case-control study

Askling J; Klareskog L; Blomqvist P; Fored M; Feltelius N
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(8):1102-1105

Trends in disease modifying antirheumatic drug prescription in early rheumatoid arthritis are influenced more by hospital setting than patient or disease characteristics

Carli C; Ehlin AGC; Klareskog L; Lindblad S; Montgomery SM
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;63(6):444-452

FOXP3 identifies regulatory CD25^brigntCD4⁺ T cells in rheumatic joints

Cao D; Borjesson O; Larsson P; Rudin A; Gunnarsson I; Klareskog L; Malmstrom V; Trollmo C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(6):741-745

Impact of parental history on patients' cardiovascular mortality in rheumatoid arthritis

Björnådal L; Brandt L; Klareskog L; Askling J
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(5):1463-1472

Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritis

Makrygiannakis D; af Klint E; Catrina S-B; Botusan IR; Klareskog E; Klareskog L; Ulfgren A-K; Catrina AI
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(4):1063-1074

Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis - Two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial

van der Heijde D; Klareskog L; Rodriguez-Valverde V; Codreanu C; Bolosiu H; Melo-Gomes J; Tornero-Molina J; Wajdula J; Pedersen R; Fatenejad S
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(3):692-701

Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis

Baecklund E; Iliadou A; Askling J; Ekborn A; Backlin C; Granath F; Catrina AT; Rosenquist R; Feltelius N; Sundström C; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(3):328-334

Patient reported outcomes in a trial of combination therapy with etanercept and methotrexate for rheumatoid arthritis: the TEMPO trial

van der Heijde D; Klareskog L; Singh A; Tornero J; Melo-Gomes J; Codreanu C; Pedersen R; Freundlich B; Fatenejad S
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(6):R179

Effect of infliximab on mRNA expression profiles in synovial tissue of rheumatoid arthritis patients

Lindberg J; af Klint E; Catrina AI; Nilsson P; Klareskog L; Ulfgren A-K; Lundeberg J
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(1):R18

Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor

Ernestam S; Klint EA; Catrina AI; Sundberg E; Engström M; Klareskog L; Ulfgren K
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2006;35(1):7-14

A two-year follow-up of work capacity in early rheumatoid arthritis:: a study of multidisciplinary team care with emphasis on vocational support

Nordmark B; Blomqvist P; Andersson B; Hägerström B; Nordh-Grate K; Rönnqvist R; Svensson H; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(1):76-81

Anti-tumor necrosis factor therapy increases synovial osteoprotegerin expression in rheumatoid arthritis

Catrina AI; af Klint E; Ernestam S; Catrina SB; Makrygiannakis D; Botusan IR; Klareskog L; Ulfgren AK
Article: ARTHRITIS & RHEUMATOLOGY. 2006;54(1):38-46

A new model for an etiology of rheumatoid arthritis

Klareskog L; Stolt P; Lundberg K; Källberg H; Bengtsson C; Grunewald J; Rönnelid J; Harris HE; Ulfgren AK; Rantapää-Dahlqvist S; Eklund A; Padyukov L; Alfredsson L
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(2):r47

Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technology

Lindberg J; af Klint E; Ulfgren A-K; Stark A; Andersson T; Nilsson P; Klareskog L; Lundeberg J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2005;34(5):353-358

Adalimumab (Humira®) restores clinical response in patients with secondary loss of efficacy from infliximab (Remicade®) or etanercept (Enbrel®):: results from the STURE registry at Karolinska University Hospital

Wick MC; Ernestam S; Lindblad S; Bratt J; Klareskog L; van Vollenhoven RF
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2005;77(6):1044-1060

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden:: Association of susceptibility with PTPN22, CTLA4, and PADI4

Plenge RM; Padyukov L; Remmers EF; Purcell S; Lee AT; Karlson EW; Wolfe F; Kastner DL; Alfredsson L; Altshuler D; Gregersen PK; Klareskog L; Rioux JD
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(12):3880-3889

Intraarticular glucocorticoid treatment reduces inflammation in synovial cell infiltrations more efficiently than in synovial blood vessels

af Klint E; Grundtman C; Engström M; Catrina AI; Makrygiannakis D; Klareskog L; Andersson U; Ulfgren AK
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(12):1744-1749

Longitudinal analysis of citrullinated protein/peptide antibodies (anti-CP) during 5 year follow up in early rheumatoid arthritis:: anti-CP status predicts worse disease activity and greater radiological progression

Rönnelid J; Wick MC; Lampa J; Lindblad S; Nordmark B; Klareskog L; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(12):1765-1768

Do steroids increase lymphoma risk?: A case-control study of lymphoma risk in polymyalgia rheumatica/giant cell arteritis

Askling J; Klareskog L; Hjalgrim H; Baecklund E; Björkholm M; Ekbom A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(11):1582-1587

Comparison of different definitions to classify remission and sustained remission:: 1 year TEMPO results

van der Heijde D; Klareskog L; Boers M; Landewé R; Codreanu C; Bolosiu HD; Pedersen R; Fatenejad S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(11):1588-1594

Socioeconomic status and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study

Bengtsson C; Nordmark B; Klareskog L; Lundberg I; Alfredsson L
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(11):3439-3447

Effects of antirheumatic treatments on the prostaglandin E₂ Biosynthetic pathway

Korotkova M; Westman M; Gheorghe KR; af Klint E; Trollmo C; Ulfgren AK; Klareskog L; Jakobsson PJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(10):1414-1420

Haematopoietic malignancies in rheumatoid arthritis:: lymphoma risk and characteristics after exposure to tumour necrosis factor antagonists

Askling J; Fored CM; Baecklund E; Brandt L; Backlin C; Ekbom A; Sundström C; Bertilsson L; Cöster L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapää-Dahlqvist S; Saxne T; Klareskog L; Feltelius N
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(10):1421-1426

Risks of solid cancers in patients with rheumatoid arthritis and after treatment with tumour necrosis factor antagonists

Askling J; Fored CM; Brandt L; Baecklund E; Bertilsson L; Feltelus N; Cöster L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapää-Dahlqvist S; Saxne T; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(8):1174-1179

Cost effectiveness of etanercept (Enbrel) in combination with methotrexate in the treatment of active rheumatoid arthritis based on the TEMPO trial

Kobelt G; Lindgren P; Singh A; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(7):1986-1992

Risk and case characteristics of tuberculosis in rheumatoid arthritis associated with tumor necrosis factor antagonists in Sweden

Askling J; Fored CM; Brandt L; Baecklund E; Bertilsson L; Cöster L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapää-Dahlqvist S; Saxne T; Romanus V; Klareskog L; Feltelius N
Article: NATURE GENETICS. 2005;37(5):486-494

MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

Swanberg M; Lidman O; Padyukov L; Eriksson P; Åkesson E; Jagodic M; Lobell A; Khademi M; Borjesson O; Lindgren CM; Lundman P; Brookes AJ; Kere J; Luthman H; Alfredsson L; Hillert J; Klareskog L; Hamsten A; Piehl F; Olsson T
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(4):654

Feasibility of 1 hour infliximab infusions

van Vollenhoven RF; Gullström E; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(4):582-586

Silica exposure is associated with increased risk of developing rheumatoid arthritis:: results from the Swedish EIRA study

Stolt P; Källberg H; Lundberg I; Sjögren B; Klareskog L; Alfredsson L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(3):494-496

CNI-1493, an inhibitor of proinflammatory cytokines, retards cartilage destruction in rats with collagen induced arthritis

Larsson E; Harris HE; Palmblad K; Månsson B; Saxne T; Klareskog L
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2005;40(2):170-174

Antitissue transglutaminase and antithyroid autoantibodies in children with Down syndrome and celiac disease

Hansson T; Dahlborn T; Rogberg S; Nyberg BI; Dahlström J; Annerén G; Klareskog L; Dannaeus A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(2):246-252

Results from a nationwide postmarketing cohort study of patients in Sweden treated with etanercept

Feltelius N; Fored CM; Blomqvist P; Bertilsson L; Geborek P; Jacobsson LT; Lindblad S; Lysholm J; Rantapää-Dahlqvist S; Saxne T; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(1):61-72

Evidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints - Extended report

Catrina AI; Trollmo C; af Klint E; Engstrom M; Lampa J; Hermansson Y; Klareskog L; Ulfgren AK
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(1):49-60

Presentation and analysis of data on radiographic outcome in clinical trials -: Experience from the TEMPO study

van der Heijde D; Landewé R; Klareskog L; Rodríguez-Valverde V; Settas L; Pedersen R; Fatenejad S
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(1):192-200

Lipid peroxidation is enhanced in patients with systemic lupus erythematosus and is associated with arterial and renal disease manifestations

Frostegård J; Svenungsson E; Wu RH; Gunnarsson I; Lundberg IE; Klareskog L; Hörkko S; Witztum JL
Article: ARTHRITIS RESEARCH & THERAPY. 2005;7(3):R458-R467

Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity

Lundberg K; Nijenhuis S; Vossenaar ER; Palmblad K; van Venrooij WJ; Klareskog L; Zendman AJW; Harris HE
Article: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(1):134-137

Estimated prediagnosis radiological progression: an important tool for studying the effects of early disease modifying antirheumatic drug treatment in rheumatoid arthritis

Wick MC; Lindblad S; Weiss RJ; Klareskog L; van Vollenhoven RF
Article: ARTHRITIS RESEARCH & THERAPY. 2005;7(6):R1296-R1303

Association between occupational exposure to mineral oil and rheumatoid arthritis:: results from the Swedish EIRA case-control study

Sverdrup B; Källberg H; Bengtsson C; Lundberg I; Padyukov L; Alfredsson L; Klareskog L
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2004;33(6):423-427

Biopsy-verified response of severe lupus nephritis to treatment with rituximab (anti-CD20 monoclonal antibody) plus cyclophosphamide after biopsy-documented failure to respond to cyclophosphamide alone

van Vollenhoven RF; Gunnarsson I; Welin-Henriksson E; Sundelin B; Österborg A; Jacobson SH; Klareskog L
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2004;33(6):380-384

Clinical and radiological disease-course in a Swedish DMARD-treated early RA-inception cohort: an observational study

Wick MC; Lindblad S; Weiss RJ; Klareskog L; van Vollenhoven RF
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(10):3085-3092

A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis

Padyukov L; Silva C; Stolt P; Alfredsson L; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(9):1075-1078

Treatment with tumour necrosis factor a antagonists in patients with rheumatoid arthritis induces anticardiolipin antibodies

Jonsdottir T; Forslid J; van Vollenhoven A; Harju A; Brannemark S; Klareskog L; van Vollenhoven RF
Article: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(7):848-852

Relationship between inflammation and joint destruction in early rheumatoid arthritis: a mathematical description

Wick MC; Lindblad S; Klareskog L; van Vollenhoven RF
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(6):1774-1780

Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synovium

Westman M; Korotkova M; af Klint E; Stark A; Audoly LP; Klareskog L; Ulfgren AK; Jakobsson P
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(6):1770-1773

Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope

Prokunina L; Padyukov L; Bennet A; de Faire U; Wiman B; Prince J; Alfredsson L; Klareskog L; Alarcón-Riquelme M
Article: JOURNAL OF RHEUMATOLOGY. 2004;31(4):713-719

Cardiovascular disease a hazard despite improved prognosis in patients with systemic lupus erythematosus:: Results from a Swedish population based study 1964-95

Björnådal L; Yin L; Granath F; Klareskog L; Ekbom A
Article: AMERICAN JOURNAL OF THE MEDICAL SCIENCES. 2004;327(4):196-201

The additive role of innate and adaptive immunity in the development of arthritis

Malmström V; Trollmo C; Klareskog L
Article: RHEUMATOLOGY. 2004;43(4):428-434

Corticosteroid treatment of experimental arthritis retards cartilage destruction as determined by histology and serum COMP

Larsson E; Harris HE; Larsson A; Månsson B; Saxne T; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(4):426-430

Dose escalation of infliximab in clinical practice: improvements seen may be explained by a regression-like effect

van Vollenhoven RF; Brannemark S; Klareskog L
Article: JOURNAL OF RHEUMATOLOGY. 2004;31(3):422-425

Polymorphism in promoter region of IL10 gene is associated with rheumatoid arthritis in women

Padyukov L; Hytönen AM; Smolnikova M; Hahn-Zoric M; Nilsson N; Hanson L; Tarkowski A; Klareskog L
Article: LANCET. 2004;363(9410):675-681

Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial

Klareskog L; van der Heijde D; de Jager JP; Gough A; Kalden J; Malaise M; Mola EM; Pavelka K; Sany J; Settas L; Wajdula J; Pedersen R; Fatenejad S; Sanda M
Article: BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY. 2004;18(1):7-19

Corticosteroids - from an idea to clinical use

Lundberg IE; Grundtman C; Larsson E; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(1):297-304

Oligodeoxynucleotides containing CpG motifs can induce T cell-dependent arthritis in rats

Svelander L; Harris HE; Lorentzen JC; Trollmo C; Klareskog L; Bucht A
Article: ARTHRITIS RESEARCH & THERAPY. 2004;6(4):R335-R346

CD25^brightCD4⁺ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

Cao DJ; van Vollenhoven R; Klareskog L; Trollmo C; Malmström V
Article: ARTHRITIS RESEARCH & THERAPY. 2004;6(4):R303-R308

A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis

Berglin E; Padyukov L; Sundin U; Hallmans G; Stenlund H; van Venrooij WJ; Klareskog L; Dahlqvist SR
Article: ANNALS OF THE RHEUMATIC DISEASES. 2003;62(12):1195-1198

Treatment with infliximab (Remicade) when etanercept (Enbrel) has failed or vice versa:: data from the STURE registry showing that switching tumour necrosis factor α blockers can make sense

van Vollenhoven R; Harju A; Brannemark S; Klareskog L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;107(1):112-119

Dynamic expression of transforming growth factor-betas (TGF-beta) and their type I and type II receptors in the synovial tissue of arthritic rats

Mussener A; Funa K; Kleinau S; Klareskog L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;108(3):415-419

Amelioration of collagen II-induced arthritis in rats by the type IV phosphodiesterase inhibitor Rolipram

Nyman U; Mussener A; Larsson E; Lorentzen J; Klareskog L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;107(3):485-493

Cytokine production in synovial tissue of mice with collagen-induced arthritis (CIA)

Mussener A; Litton MJ; Lindroos E; Klareskog L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;107(3):480-484

Characteristics of synovial fluid effusion in collagen-induced arthritis (CIA) in the DA rat; A comparison of histology and antibody reactivities in an experimental chronic arthritis model and rheumatoid arthritis (RA)

Harris HE; Liljestrom M; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(9):2533-2540

Elevated triglycerides and low levels of high-density lipoprotein as markers of disease activity in association with up-regulation of the tumor necrosis factor α/tumor necrosis factor receptor system in systemic lupus erythematosus

Svenungsson E; Gunnarsson I; Fei GZ; Lundberg IE; Klareskog L; Frostegård J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2003;62(9):835-841

Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases

Stolt P; Bengtsson C; Nordmark B; Lindblad S; Lundberg I; Klareskog L; Alfredsson L
Article: JOURNAL OF RHEUMATOLOGY. 2003;30(8):1748-1755

Evidence for immunostimulatory effects of intramuscular gold in patients with rheumatoid arthritis:: Correlation with skin reactions

Ernestam S; Lampa J; Rogberg S; Rönnelid J; Klareskog L; Hafström I
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(6):1543-1550

Lymphoma subtypes in patients with rheumatoid arthritis -: Increased proportion of diffuse large B cell lymphoma

Baecklund E; Sundström C; Ekbom A; Catrina AI; Biberfeld P; Feltelius N; Klareskog L
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(6):1500-1503

Clinical responses to tumor necrosis factor α antagonists do not show a bimodal distribution -: Data from the Stockholm tumor necrosis factor α followup registry

van Vollenhoven RF; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2003;62(6):526-529

Genetic markers for the efficacy of tumour necrosis factor blocking therapy in rheumatoid arthritis

Padyukov L; Lampa J; Heimbürger M; Ernestam S; Cederholm T; Lundkvist I; Andersson P; Hermansson Y; Harju A; Klareskog L; Bratt J
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(4):963-970

Risk of malignant lymphomas in patients with rheumatoid arthritis and in their first-degree relatives

Ekström K; Hjalgrim H; Brandt L; Baecklund E; Klareskog L; Ekbom A; Askling J
Article: LAKARTIDNINGEN. 2003;100(8):631-632

[The proposal of the National Board of Health and Welfare counteracts knowledge development within health care].

Klareskog L; Efendic S; Brismar K; Hamsten A
Article: ARTHRITIS RESEARCH & THERAPY. 2003;5(6):R347-R351

Etanercept versus etanercept plus methotrexate: a registry-based study suggesting that the combination is clinically more efficacious

van Vollenhoven RF; Ernestam S; Harju A; Bratt J; Klareskog L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2003;33(1):215-223

Isolation and functional characterization of regulatory CD25^brightCD4⁺ T cells from the target organ of patients with rheumatoid arthritis

Cao D; Malmström V; Baecher-Allan C; Hafler D; Klareskog L; Trollmo C
Article: LANCET. 2002;360(9349):1935-1939

Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia

Thunberg U; Tobin G; Johnson A; Söderberg O; Padyukov L; Hultdin M; Klareskog L; Enblad G; Sundström C; Roos G; Rosenquist R
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2002;56(5):530-537

Transforming growth factor-β (TGF-β) and tissue transglutaminase expression in the small intestine in children with coeliac disease

Hansson T; Ulfgren AK; Lindroos E; Dannæus A; Dahlbom I; Klareskog L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2002;61(10):934-936

Low levels of apoptosis and high FLIP expression in early rheumatoid arthritis synovium

Catrina AI; Ulfgren AK; Lindblad S; Grondal L; Klareskog L
Article: RHEUMATOLOGY. 2002;41(9):996-1000

Serum concentrations of cartilage oligomeric matrix protein, fibrinogen and hyaluronan distinguish inflammation and cartilage destruction in experimental arthritis in rats

Larsson E; Harris HE; Lorentzen JC; Larsson A; Månsson B; Klareskog L; Saxne T
Article: PEDIATRIC RESEARCH. 2002;51(6):700-705

Recombinant human tissue transglutaminase for diagnosis and follow-up of childhood coeliac disease

Hansson T; Dahlbom I; Rogberg S; Dannæus A; Höpfl P; Gut H; Kraaz W; Klareskog L
Article: JOURNAL OF RHEUMATOLOGY. 2002;29(5):906-912

Decreasing mortality in patients with rheumatoid arthritis:: Results from a large population based cohort in Sweden, 1964-95

Björnådal L; Baecklund E; Yin L; Granath F; Klareskog L; Ekbom A
Article: RHEUMATOLOGY. 2002;41(5):484-489

Anti-tumour necrosis factor (TNF)-α therapy (etanercept) down-regulates serum matrix metalloproteinase (MMP)-3 and MMP-1 in rheumatoid arthritis

Catrina AI; Lampa J; Ernestam S; af Klint E; Bratt J; Klareskog L; Ulfgren AK
Article: ARTHRITIS & RHEUMATOLOGY. 2002;46(4):1044-1055

Interleukin-1α expression in capillaries and major histocompatibility complex class I expression in type II muscle fibers from polymyositis and dermatomyositis patients -: Important pathogenic features independent of inflammatory cell clusters in muscle tissue

Englund P; Nennesmo I; Klareskog L; Lundberg IE
Article: JOURNAL OF RHEUMATOLOGY. 2002;29(1):21-28

Effects of gold on cytokine production in vitro;: Increase of monocyte dependent interleukin 10 production and decrease of interferon-γ levels

Lampa J; Klareskog L; Rönnelid J
Article: LUPUS. 2002;11(7):435-442

Increased T-lymphocyte apoptosis/necrosis and IL-10 producing cells in patients and their spouses in Icelandic systemic lupus erythematosus multicase families

Gröndal G; Traustadottir KH; Kristjansdottir H; Lundberg I; Klareskog L; Erlendsson K; Steinsson K
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;114(2):277-283

A vitamin D analogue (MC 1288) has immunomodulatory properties and suppresses collagen-induced arthritis (CIA) without causing hypercalcaemia

Larsson P; Mattsson L; Klareskog L; Johnsson C
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;115(1):32-41

Anti-inflammatory effects of a new tumour necrosis factor-alpha (TNF-α) inhibitor (CNI-1493) in collagen-induced arthritis (CIA) in rats

Åkerlund K; Harris HE; Tracey KJ; Wang H; Fehniger T; Klareskog L; Andersson J; Andersson U
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;120(1):174-182

Down-regulation of the T cell receptor CD3ζ chain in rheumatoid arthritis (RA) and its influence on T cell responsiveness

Berg L; Rönnelid J; Klareskog L; Bucht A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;122(3):477-483

Parasite-mediated down-regulation of collagen-induced arthritis (CIA) in DA rats

Mattsson L; Larsson P; Erlandsson-Harris H; Klareskog L; Harris RA
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;116(2):246-250

Cytokine-producing cells in peripheral blood of children with coeliac disease secrete cytokines with a type 1 profile

Hansson T; Dannæus A; Klareskog L
Article: RHEUMATOLOGY. 2001;40(10):1175-1179

A vegan diet free of gluten improves the signs and symptoms of rheumatoid arthritis:: the effects on arthritis correlate with a reduction in antibodies to food antigens

Hafström I; Ringertz B; Spångberg A; von Zweigbergk L; Brannemark S; Nylander I; Rönnelid J; Laasonen L; Klareskog L
Article: AMERICAN JOURNAL OF PATHOLOGY. 2001;159(4):1263-1273

Skeletal muscle fibers express major histocompatibility complex class II antigens independently of inflammatory infiltrates in inflammatory myopathies

Englund P; Lindroos E; Nennesmo I; Klareskog L; Lundberg IE
Article: HUMAN MOLECULAR GENETICS. 2001;10(18):1901-1906

High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis

Barton A; Eyre S; Myerscough A; Brintnell B; Ward D; Ollier WER; Lorentzen JC; Klareskog L; Silman A; John S
Article: LIFE SCIENCES. 2001;69(15):1775-1782

Binding, pharmacological and immunological profiles of the δ-selective opioid receptor antagonist HS 378

Spetea M; Harris HE; Berzetei-Gurske IP; Klareskog L; Schmidhammer H
Article: ANNALS OF THE RHEUMATIC DISEASES. 2001;60(4):372-379

Increased levels of proinflammatory cytokines and nitric oxide metabolites in neuropsychiatric lupus erythematosus

Svenungsson E; Andersson M; Brundin L; van Vollenhoven R; Khademi M; Tarkowski A; Greitz D; Dahlström M; Lundberg I; Klareskog L; Olsson T
Article: BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY. 2001;15(1):1-15

On the organization of an early arthritis clinic

Klareskog L; Nordmark B; Lindblad S
Article: ANNALS OF THE RHEUMATIC DISEASES. 2001;60(2):133-139

Increased peripheral T cell reactivity to microbial antigens and collagen type II in rheumatoid arthritis after treatment with soluble TNFα receptors

Berg L; Lampa J; Rogberg S; van Vollenhoven R; Klareskog L
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2001;30(5):282-289

Longitudinal study of interleukin-10, tumor necrosis factor-α, anti-U1-snRNP antibody levels and disease activity in patients with mixed connective tissue disease

Hassan AB; Gunnarsson I; Karlsson G; Klareskog L; Forslid J; Lundberg IE
Article: GENOMICS. 2000;70(3):307-314

Fine mapping of the SLEB2 locus involved in susceptibility to systemic lupus erythematosus

Magnusson V; Lindqvist AKB; Castillejo-López C; Kristjánsdottir H; Steinsson K; Gröndal G; Sturfelt G; Truedsson L; Svenungsson E; Lundberg I; Gunnarsson I; Bolstad AI; Haga HJ; Jonsson R; Klareskog L; Alcocer-Varela J; Alarcón-Segovia D; Terwilliger JD; Gyllensten UB; Alarcón-Riquelme ME
Article: ARTHRITIS & RHEUMATOLOGY. 2000;43(11):2391-2396

Systemic anti-tumor necrosis factor α therapy in rheumatoid arthritis down-regulates synovial tumor necrosis factor α synthesis

Ulfgren AK; Andersson U; Engström M; Klareskog L; Maini RN; Taylor PC
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2000;18(5):565-570

Cytokine production, serum levels and disease activity in systemic lupus erythematosus

Gröndal G; Gunnarsson I; Rönnelid J; Rogberg S; Klareskog L; Lundberg I
Article: ACTA DERMATO-VENEREOLOGICA. 2000;80(3):167-170

An immunohistochemical analysis of cytokine expression in allergic and irritant contact dermatitis

Ulfgren AK; Klareskog L; Lindberg M
Article: RHEUMATOLOGY. 2000;39(8):886-893

Development of lupus-related side-effects in patients with early RA during sulphasalazine treatment -: the role of IL-10 and HLA

Gunnarsson I; Nordmark B; Bakri AH; Gröndal G; Larsson P; Forslid J; Klareskog L; Ringertz B
Article: ANNALS OF THE RHEUMATIC DISEASES. 2000;59(7):504-505

Consensus statement on the initiation and continuation of tumour necrosis factor blocking therapies in rheumatoid arthritis

Smolen JS; Breedveld FC; Burmester GR; Combe B; Emery P; Kalden JR; Klareskog L; Maini RN; Numo R; van de Putte LBA; van Riel PLCM; Rodriguez-Valverde V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2000;59(6):439-447

Interindividual and intra-articular variation of proinflammatory cytokines in patients with rheumatoid arthritis:: potential implications for treatment

Ulfgren AK; Gröndal L; Lindblad S; Khademi M; Johnell O; Klareskog L; Andersson U
Article: JOURNAL OF RHEUMATOLOGY. 2000;27(5):1171-1177

Rheumatoid arthritis in Sweden. Drug prescriptions, costs, and adverse drug reactions

Blomqvist P; Feltelius N; Ekbom A; Klareskog L
Article: JOURNAL OF AUTOIMMUNITY. 2000;14(3):267-274

Kinetics of anti-fibrillin-1 autoantibodies in MCTD and CREST syndrome

Lundberg I; Antohi S; Takeuki K; Arnett F; Steiner G; Brumeanu TD; Klareskog L; Bona C
Article: LAKARTIDNINGEN. 2000;97(17):2110-2111

[Current medicine requires cooperation--not omnipotence].

Klareskog L
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2000;30(4):379-384

Antibody reactivity against human and guinea pig tissue transglutaminase in children with celiac disease

Hansson T; Dahlbom I; Hall J; Holtz A; Elfman L; Dannaeus A; Klareskog L
Article: LAKARTIDNINGEN. 2000;97(1-2):30-33

[Future treatment of rheumatism. A compromise in the game between inflammation and infections].

Klareskog L; Lundberg I
Article: JOURNAL OF RHEUMATOLOGY. 1999;26(10):2148-2152

Genetic analysis of the contribution of IL10 to systemic lupus erythematosus

Alarcón-Riquelme ME; Lindqvist AKB; Jonasson I; Johanneson B; Sandino S; Alcocer-Varela J; Granados J; Kristjánsdóttir H; Gröndal G; Svenungsson E; Lundberg I; Steinsson K; Klareskog L; Sturfelt G; Truedsson L; Alarcon-Segovia D; Gyllensten UB
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1999;29(3):286-292

Celiac disease in relation to immunologic serum markers, trace elements, and HLA-DR and DQ antigens in Swedish children with Down syndrome

Hansson T; Annerén G; Sjöberg O; Klareskog L; Dannæus A
Article: ARTHRITIS & RHEUMATOLOGY. 1999;42(8):1649-1654

Increased number of interleukin-10-producing cells in systemic lupus erythematosus patients and their first-degree relatives and spouses in Icelandic multicase families

Gröndal G; Kristjansdottir H; Gunnlaugsdottir B; Arnason A; Lundberg I; Klareskog L; Steinsson K
Article: SURGERY. 1998;124(3):503-509

Major histocompatibility complex class II expression and parathyroid autoantibodies in primary hyperparathyroidism

Bjerneroth G; Juhlin C; Gudmundsson S; Rastad J; Åkerström G; Klareskog L
Article: BMJ-BRITISH MEDICAL JOURNAL. 1998;317(7152):180-181

Disease activity and risk of lymphoma in patients with rheumatoid arthritis:: nested case-control study

Baecklund E; Ekbom A; Sparén P; Feltelius N; Klareskog L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(11):6383-6387

Identification of rat susceptibility loci for adjuvant-oil-induced arthritis

Lorentzen JC; Glaser A; Jacobsson L; Galli J; Fakhrai-Rad H; Klareskog L; Luthman H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1998;47(3):254-262

Decreased expression of signal-transducing CD3 ζ chains in T cells from the joints and peripheral blood of rheumatoid arthritis patients

Matsuda M; Ulfgren AK; Lenkei R; Petersson M; Ochoa AC; Lindblad S; Andersson P; Klareskog L; Kiessling R
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 1998;106(1):27-32

Common commercial cosmetic products induce arthritis in the DA rat

Sverdrup B; Klareskog L; Kleinau S
Article: BRITISH JOURNAL OF RHEUMATOLOGY. 1998;37(1):7-14

Production of T-cell cytokines at the single-cell level in patients with inflammatory arthritides:: Enhanced activity in synovial fluid compared to blood

Rönnelid J; Berg L; Rogberg S; Nilsson A; Albertsson K; Klareskog L
Article: BRITISH JOURNAL OF RHEUMATOLOGY. 1997;36(12):1258-1261

Increased serum levels of cartilage oligomeric matrix protein and bone sialoprotein in rats with collagen arthritis

Larsson E; Müssener Å; Heinegård D; Klareskog L; Saxne T
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;46(6):619-624

Immunization with alum-collagen II complex suppresses the development of collagen-induced arthritis in rats by deviating the immune response

Mattsson L; Lorentzen JC; Svelander L; Bucht A; Nyman U; Klareskog L; Larsson P
Article: ARTHRITIS & RHEUMATOLOGY. 1997;40(5):865-874

Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies

Lundberg I; Ulfgren AK; Nyberg P; Andersson U; Klareskog L
Article: PEDIATRIC RESEARCH. 1997;41(4):554-559

Production of antibodies to gliadin by peripheral blood lymphocytes in children with celiac disease: The use of an enzyme-linked immunospot technique for screening and follow-up

Hansson T; Dannaeus A; Kraaz W; Sjoberg O; Klareskog L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(3):695-699

Altered Th1/Th2 balance associated with nonmajor histocompatibility complex genes in collagen-induced arthritis in resistant and nonresistant rat strains

Mussener A; Lorentzen JC; Kleinau S; Klareskog L
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 1997;200(1-2):17-26

A comparison between ELISPOT methods for the detection of cytokine producing cells: Greater sensitivity and specificity using ELISA plates as compared to nitrocellulose membranes

Ronnelid J; Klareskog L
Article: LAKARTIDNINGEN. 1997;94(1-2):24-27

[New perspectives on rheumatoid arthritis].

Klareskog L
Article: BRITISH JOURNAL OF RHEUMATOLOGY. 1997;36(1):32-37

Association between ongoing anti-Clq antibody production in peripheral blood and proliferative nephritis in patients with active systemic lupus erythematosus

Gunnarsson I; Ronnelid J; Huang YH; Rogberg S; Nilsson B; Lundberg I; Klareskog L
Article: UGESKRIFT FOR LAEGER. 1996;158(51):7379-7383

[Nobel Prize for discovery of the cell-mediated immune defence].

Klareskog L; Kärre K; Möller E; Wigzell H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(6):592-598

Susceptibility of DA rats to arthritis induced with adjuvant oil or rat collagen is determined by genes both within and outside the major histocompatibility complex

Lorentzen JC; Klareskog L
Article: SURGERY. 1996;120(6):985-992

Expression and function of a CD4-like molecule in parathyroid tissue

Hellman P; KarlssonParra A; Klareskog L; Ridefelt P; Bjerneroth G; Rastad J; Akerstrom G; Juhlin C
Article: LAKARTIDNINGEN. 1996;93(42):3714-3717

[The Nobel Prize for discovery of the cell-mediated immune defense. Significance for clinical medicine].

Klareskog L; Kärre K; Möller E; Wigzell H
Article: JOURNAL OF NEUROIMMUNOLOGY. 1995;63(2):193-205

Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant

Lorentzen JC; Issazadeh S; Storch M; Mustafa MI; Lassman H; Linington C; Klareskog L; Olsson T
Article: ANNALS OF THE RHEUMATIC DISEASES. 1995;54(8):654-661

DETECTION OF CYTOKINE PRODUCING CELLS IN THE SYNOVIAL-MEMBRANE FROM PATIENTS WITH RHEUMATOID-ARTHRITIS

ULFGREN AK; LINDBLAD S; KLARESKOG L; ANDERSSON J; ANDERSSON U
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):128-134

TNF-ALPHA DOMINATES CYTOKINE MESSENGER-RNA EXPRESSION IN LYMPHOID-TISSUES OF RATS DEVELOPING COLLAGEN-INDUCED AND OIL-INDUCED ARTHRITIS

MUSSENER A; KLARESKOG L; LORENTZEN JC; KLEINAU S
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):82-89

SPECIFIC AND LONG-LASTING PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS AND OIL-INDUCED ARTHRITIS IN DA RATS BY ADMINISTRATION OF IMMUNOGENS

LORENTZEN JC; ERLANDSSON H; MUSSENER A; MATTSSON L; KLEINAU S; NYMAN U; KLARESKOG L
Article: INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY. 1995;17(5):393-401

OIL-INDUCED ARTHRITIS IN DA RATS - TISSUE DISTRIBUTION OF ARTHRITOGENIC C-14-LABELED HEXADECANE

KLEINAU S; DENCKER L; KLARESKOG L
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All other publications

Letter: ARTHRITIS & RHEUMATOLOGY. 2024;76(4):660-661

Clinical Images: Hairy kidney in IgG4-related disease Reply

Alfredsson L; Klareskog L; Hedstrom AK
Letter: ARTHRITIS & RHEUMATOLOGY. 2024;76(3):487-488

The link among alcohol consumption, disease progression, and quality of life in rheumatoid arthritis: comment on the article by Alfredsson et al Reply

Alfredsson L; Klareskog L; Hedstroem AK
Corrigendum: NATURE IMMUNOLOGY. 2023;24(11):1960

Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets (vol 24, pg 1540, 2023)

Zhao JH; Stacey D; Eriksson N; Macdonald-Dunlop E; Hedman AK; Kalnapenkis A; Enroth S; Cozzetto D; Digby-Bell J; Marten J; Folkersen L; Herder C; Jonsson L; Bergen SE; Gieger C; Needham EJ; Hudjasov G; Surendran P; Estonian Biobank Res Team O; Paul DS; Polasek O; Thorand B; Grallert H; Roden M; Vosa U; Esko T; Hayward C; Johansson A; Gyllensten U; Powell N; Hansson O; Mattsson-Carlgren N; Joshi PK; Danesh J; Padyukov L; Klareskog L; Landen M; Wilson JF; Siegbahn A; Wallentin L; Maelarstig A; Butterworth AS; Peters JE
Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):3923

Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality (vol 14, 3453, 2023)

Oddsson AR; Sulem P; Sveinbjornsson G; Arnadottir G; Steinthorsdottir VM; Halldorsson G; Atlason B; Oskarsson GO; Helgason H; Nielsen HS; Westergaard D; Karjalainen JA; Katrinardottir H; Fridriksdottir R; Jensson BB; Tragante V; Ferkingstad EA; Jonsson H; Gudjonsson S; Beyter D; Moore KHS; Thordardottir H; Kristmundsdottir S; Stefansson O; Rantapaeae-Dahlqvist S; Sonderby IE; Didriksen M; Stridh PA; Haavik J; Tryggvadottir L; Frei O; Walters GB; Kockum I; Hjalgrim H; Olafsdottir T; Selbaek G; Nyegaard M; Erikstrup C; Brodersen T; Saevarsdottir S; Olsson T; Nielsen KR; Haraldsson A; Bruun MT; Hansen TF; Steingrimsdottir TT; Jacobsen RL; Lie R; Djurovic S; Alfredsson L; Lopez de Lapuente Portilla A; Brunak SV; Melsted P; Halldorsson B; Saemundsdottir J; Magnusson OT; Padyukov L; Banasik K; Rafnar T; Askling J; Klareskog L; Pedersen OB; Masson G; Havdahl AA; Nilsson B; Andreassen O; Daly M; Ostrowski SR; Jonsdottir I; Stefansson H; Holm H; Helgason A; Thorsteinsdottir UF; Stefansson K; Gudbjartsson D
Review: IMMUNOTHERAPY ADVANCES. 2023;3(1):ltad016

Prevention vs treatment of rheumatoid arthritis

Klareskog L; Alfredsson L
Letter: ARTHRITIS RESEARCH & THERAPY. 2022;24(1):239

Response to Comment "Sex-specific exposures and sex-combined outcomes in two-sample Mendelian randomization may mislead the causal inference" on "Age at menarche, age at natural menopause, and risk of rheumatoid arthritis-a Mendelian randomization study"

Zhu J; Niu Z; Alfredsson L; Klareskog L; Padyukov L; Jiang X
Corrigendum: NATURE REVIEWS IMMUNOLOGY. 2022;22(7):459

The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting (vol 17, pg 60, 2017)

Malmstrom V; Catrina AI; Klareskog L
Editorial comment: NATURE REVIEWS RHEUMATOLOGY. 2022;18(1):7-8

Passive smoking in childhood accelerates RA risk for smokers

Klareskog L
Letter: ARTHRITIS & RHEUMATOLOGY. 2021;73(10):1944-1945

Untitled Reply

Tang B; Alfredsson L; Klareskog L; Padyukov L; Shi H; Jiang X
Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(3):602-620

Technological readiness and implementation of genomic-driven precision medicine for complex diseases

Franks PW; Melen E; Friedman M; Sundstrom J; Kockum I; Klareskog L; Almqvist C; Bergen SE; Czene K; Hagg S; Hall P; Johnell K; Malarstig A; Catrina A; Hagstrom H; Benson M; Smith JG; Gomez MF; Orho-Melander M; Jacobsson B; Halfvarson J; Repsilber D; Oresic M; Jern C; Melin B; Ohlsson C; Fall T; Ronnblom L; Wadelius M; Nordmark G; Johansson A; Rosenquist R; Sullivan PF
Review: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(8):1921-1933

Towards prevention of autoimmune diseases: The example of rheumatoid arthritis

Hensvold A; Klareskog L
Other: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(6):1309

Anca Catrina 1971-2021 Obituary

Klareskog L; Rethi B; Hensvold A; Wahamaa H; Jakobsson P-J
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2020;79(12):e164

How to communicate in science

Klareskog L; Catrina AI; Svensson C; Malmstrom V
Letter: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020;38(5):1029-1030

Occupational physical workload and development of anti-collagen type II antibodies in rheumatoid arthritis: results from the Swedish EIRA population-based case-control study

Zeng P; Pertsinidou E; Brynedal B; Manivel VA; Klareskog L; Mullazehi M; Saevarsdottir S; Bengtsson C; Alfredsson L; Ronnelid J
Review: JOURNAL OF INTERNAL MEDICINE. 2020;287(5):514-533

The importance of differences; On environment and its interactions with genes and immunity in the causation of rheumatoid arthritis

Klareskog L; Ronnelid J; Saevarsdottir S; Padyukov L; Alfredsson L
Corrigendum: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;105(4):880

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype (vol 105, pg 616, 2019)

Terao C; Brynedal B; Chen Z; Jiang X; Westerlind H; Hansson M; Jakobsson P-J; Lundberg K; Skriner K; Serre G; Ronnelid J; Mathsson-Alm L; Brink M; Dahlqvist SR; Padyukov L; Gregersen PK; Barton A; Alfredsson L; Klareskog L; Raychaudhuri S
Editorial comment: CLINICAL THERAPEUTICS. 2019;41(7):1232-1234

Understanding and Prevention of the Evolution Toward Autoimmune Rheumatoid Arthritis: The New Challenge

Klareskog L
Editorial comment: GENOME MEDICINE. 2019;11(1):9

Translating genomic medicine to the clinic: challenges and opportunities

Zhang H; Klareskog L; Matussek A; Pfister SM; Benson M
Letter: ARTHRITIS & RHEUMATOLOGY. 2019;71(2):325-327

The specificity of monoclonal anti-citrullinated protein antibodies: comment on the article by Steen et al Reply

Malmstrom V; Steen J; Klareskog L
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(8):1238-1241

Amount of smoking, duration of smoking cessation and their interaction with silica exposure in the risk of rheumatoid arthritis among males: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study

Zeng P; Chen Z; Klareskog L; Alfredsson L; Bengtsson C; Jiang X
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(8):1236-1238

Seropositivity combined with smoking is associated with increased prevalence of periodontitis in patients with rheumatoid arthritis

Eriksson K; Nise L; Alfredsson L; Catrina AI; Askling J; Lundberg K; Klareskog L; Yucel-Lindberg T
Letter: ARTHRITIS CARE & RESEARCH. 2018;70(8):1276

From job title to occupational lifetime exposure assessment and the use of job-exposure matrices: comment on the article by Ilar et al Reply

Ilar A; Alfredsson L; Wiebert P; Klareskog L; Bengtsson C
Review: NATURE REVIEWS RHEUMATOLOGY. 2017;13(2):79-86

Mechanisms leading from systemic autoimmunity to joint-specific disease in rheumatoid arthritis

Catrina AI; Svensson CI; Malmstrom V; Schett G; Klareskog L
Review: NATURE REVIEWS IMMUNOLOGY. 2017;17(1):60-75

The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting

Malmstrom V; Catrina AI; Klareskog L
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(5):943-946

High sodium chloride consumption enhances the effects of smoking but does not interact with SGK1 polymorphisms in the development of ACPA-positive status in patients with RA

Jiang X; Sundstrom B; Alfredsson L; Klareskog L; Rantapaa-Dahlqvist S; Bengtsson C
Review: CURRENT OPINION IN RHEUMATOLOGY. 2016;28(2):181-188

Is rheumatoid arthritis an autoimmune disease?

Chemin K; Klareskog L; Malmstrom V
Editorial comment: RHEUMATOLOGY. 2016;55(1):1-3

Predicting and preventing the development of rheumatoid arthritis

Raza K; Klareskog L; Holers VM
Review: IMMUNOLOGICAL REVIEWS. 2016;269(1):162-174

Mechanisms involved in triggering rheumatoid arthritis

Catrina AI; Joshua V; Klareskog L; Malmstrom V
Editorial comment: NATURE REVIEWS RHEUMATOLOGY. 2015;11(5):261-262

Lungs and citrullination

Klareskog L; Catrina AI
Editorial comment: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2015;313(16):1623-1624

The Genetics of Rheumatoid Arthritis New Insights and Implications

Felson DT; Klareskog L
Editorial comment: NATURE REVIEWS DRUG DISCOVERY. 2015;14(3):149-150

Preclinical target validation using patient-derived cells

Edwards AM; Arrowsmith CH; Bountra C; Bunnage ME; Feldmann M; Knight JC; Patel DD; Prinos P; Taylor MD; Sundstrom M
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(12):e79

Response to: 'Obesity and comorbidity are independently associated with a failure to achieve remission in patients with established rheumatoid arthritis' by Ellerby et al

Sandberg MEC; Bengtsson C; Kallberg H; Wesley A; Klareskog L; Alfredsson L; Saevarsdottir S
Review: NATURE REVIEWS RHEUMATOLOGY. 2014;10(11):645-653

Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis

Catrina AI; Ytterberg AJ; Reynisdottir G; Malmstrom V; Klareskog L
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(7):e46

The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis? Antibodies against uncitrullinated peptides seem to occur prior to the antibodies to the corresponding citrullinated peptides

Brink M; Hansson M; Ronnelid J; Klareskog L; Dahlqvist SR
Letter: ARTHRITIS & RHEUMATOLOGY. 2014;66(6):1683-1684

Studies of preclinical rheumatoid arthritis synovial histology-a comparison of animal models: comment on the article by de Hair et al Reply

de Hair MJH; van de Sande MGH; Ramwadhdoebe TH; van der Leij C; Maas M; Hansson M; Klareskog L; Landewe R; Serre G; van Schaardenburg D; Gerlag DM; van Baarsen LGM; Tak PP
Review: CURRENT OPINION IN RHEUMATOLOGY. 2014;26(1):72-79

Adaptive immunity in rheumatoid arthritis: anticitrulline and other antibodies in the pathogenesis of rheumatoid arthritis

Klareskog L; Amara K; Malmstrom V
Review: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2014;114(1):13-17

Neutralization of AntiCitrullinated Protein Antibodies in Rheumatoid Arthritis - A Way to Go?

Cerqueira CF; Klareskog L; Jakobsson P-J
Letter: NATURE GENETICS. 2013;45(5):468-469

Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge

Plenge RM; Greenberg JD; Mangravite LM; Derry JMJ; Stahl EA; Coenen MJH; Barton A; Padyukov L; Klareskog L; Gregersen PK; Mariette X; Moreland LW; Bridges SLJ; de Vries N; Huizinga TWJ; Guchelaar H-J; Friend SH; Stolovitzky G
Review: ADVANCES IN IMMUNOLOGY, VOL 150. 2013;118:129-158

Autoimmunity in Rheumatoid Arthritis: Citrulline Immunity and Beyond

Klareskog L; Lundberg K; Malmstrom V
Review: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(5):638-641

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

Gerlag DM; Raza K; van Baarsen LGM; Brouwer E; Buckley CD; Burmester GR; Gabay C; Catrina AI; Cope AP; Cornelis F; Dahlqvist SR; Emery P; Eyre S; Finckh A; Gay S; Hazes JM; van der Helm-van Mil A; Huizinga TWJ; Klareskog L; Kvien TK; Lewis C; Machold KP; Ronnelid J; van Schaardenburg D; Schett G; Smolen JS; Thomas S; Worthington J; Tak PP
Review: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(10):1713-1718

Biomarkers and personalised medicine in rheumatoid arthritis: a proposal for interactions between academia, industry and regulatory bodies

Miossec P; Verweij CL; Klareskog L; Pitzalis C; Barton A; Lekkerkerker F; Reiter S; Laslop A; Breedveld F; Abadie E; Flamion B; Dere W; Mpofu S; Goel N; Ethgen D; Mitlak B; Ormarsdottir S; Rao R; Tsouderos Y; Reginster J-Y
Review: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(8):1357-1362

Animal models for arthritis: innovative tools for prevention and treatment

Kollias G; Papadaki P; Apparailly F; Vervoordeldonk MJ; Holmdahl R; Baumans V; Desaintes C; Di Santo J; Distler J; Garside P; Hegen M; Huizinga TWJ; Juengel A; Klareskog L; McInnes I; Ragoussis I; Schett G; 't Hart B; Tak PP; Toes R; van den Berg W; Wurst W; Gay S
Editorial comment: NATURE MEDICINE. 2011;17(7):790-791

Pulling the plug on atherosclerosis Cooling down the inflammasome

Hansson GK; Klareskog L
Letter: LEUKEMIA & LYMPHOMA. 2011;52(6):1146-1149

LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma

Baecklund E; Backlin C; Mansouri M; Klareskog L; Askling J; Iliadou AN; Enblad G; Lossos IS; Natkunam Y; Rosenquist R
Review: SEMINARS IN IMMUNOLOGY. 2011;23(2):92-98

Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis

Klareskog L; Malmstrom V; Lundberg K; Padyukov L; Alfredsson L
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A66

A MULTIPLEX MICROARRAY FOR THE DETECTION OF RHEUMATOID ARTHRITIS-ASSOCIATED AUTOANTIBODIES

Mathsson L; Hansson M; Israelsson L; Harwanegg C; Nystrand M; Klareskog L; Ronnelid J
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A21

META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IN CELIAC DISEASE AND RHEUMATOID ARTHRITIS IDENTIFIES FOURTEEN NON-HLA SHARED LOCI

Zhernakova A; Stahl EA; Trynka G; Raychaudhuri S; Festen E; Franke L; Fehrmann RSN; Kurreeman FAS; Thomson B; Gupta N; Romanos J; McManus R; Ryan AW; Turner G; Remmers EF; Greco L; Toes R; Grandone E; Mazzilli MC; Rybak A; Cukrowska B; Li Y; de Bakker PIW; Gregersen PK; Worthington J; Siminovitch KA; Klareskog L; Huizinga TWJ; Wijmenga C; Plenge RM
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A16

HLA-DRB1*04 IS A NOVEL FETAL SUSCEPTIBILITY ALLELE IN CONGENITAL HEART BLOCK

Ostberg T; Gorgen S; Salomonsson S; Ding B; Eliasson H; Elfving A; Malarstig A; Alfredsson L; Klareskog L; Hamsten A; Olsson T; Padukov L; Axelsson T; Gadler F; Jonzon A; Sonesson SE; Kockum I; Wahren-Herlenius M
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A3

HUMORAL IMMUNE RESPONSE AGAINST FIBRINOGEN EPITOPES CITRULLINATED IN VIVO IN RHEUMATOID ARTHRITIS SYNOVIAL TISSUE DETECTED BY AUTOANTIBODY MULTIPLEXING

Ronnelid J; Ossipova E; Mathsson L; Catrina A; Matsson P; Israelsson L; Malmstrom V; Klareskog L; Jakobsson P-J
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A67

VACCINATION OF PATIENTS WITH PRIMARY SJOGREN'S SYNDROME REVEALS HYPERREACTIVE B CELL COMPARTMENT WITH A SKEWED MATURATION PATTERN

Brauner S; Kvarnstom M; Gorgen S; Franzen-Malmros M; Brokstad KA; Folkersen L; Trollmo C; Klareskog L; Jonsson R; Malmstrom V; Wahren-Herlenius M
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:a20-A21

NON-HLA-DRB1 RA-ASSOCIATED RISK ALLELES ASSOCIATE WITH ANTI-CCP AND SPECIFIC ACPA LEVELS

Snir O; Gomez-Cabrero D; Klich KU; Seddighzadeh M; Catrina AI; Tegner J; Klareskog L; Padyukov L; Malmstrom V
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:a13

LUNG CHANGES ARE PRESENT IN ACPA POSITIVE RA PATIENTS ALREADY AT DISEASE ONSET

Reynsdottir G; Harju A; Engstrom M; Nyren S; Nyren S; Skold M; Eklund A; Grunewald J; Klareskog L; Catrina AI
Review: ANNALS OF THE RHEUMATIC DISEASES. 2010;69(12):2062-2066

Prevention of autoimmune rheumatic disease: state of the art and future perspectives

Klareskog L; Gregersen PK; Huizinga TWJ
Letter: ARTHRITIS & RHEUMATOLOGY. 2010;62(11):3516-3517

Are antibodies to citrullinated antigens enriched in synovial fluids of patients with rheumatoid arthritis?: comment on the article by Snir et al Reply

Snir O; Klareskog L; Malmstrom V
Letter: NATURE GENETICS. 2010;42(10):816

Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis Reply

Lundberg K; Alfredsson L; Kallberg H; Mahdi H; Fisher BA; Malmstrom V; Venables PJ; Klareskog L
Letter: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2010;39(4):344-346

Non-participation in EIRA: a population-based case-control study of rheumatoid arthritis

Bengtsson C; Berglund A; Serra M-L; Nise L; Nordmark B; Klareskog L; Alfredsson L
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2010;69:a73

IDENTIFICATION AND FUNCTION OF T CELLS REACTIVE WITH CITRULLINATED VIMENTIN IN HLA-DRB1*0401 HUMANISED MICE AND RHEUMATOID ARTHRITIS PATIENTS

Snir O; Rieck M; Klich K; Klareskog L; Buckner JH; Malmstrom V
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2010;69:a4-A5

IDENTIFICATION OF SPECIFIC CITRULLINATION SITES ON FIBRINOGEN IN RA

Ossipova E; Malmstrom V; Catrina AI; Klareskog L; Zubarev R; Jakobsson P-J
Review: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(8):1240-1246

European biologicals registers: methodology, selected results and perspectives

Zink A; Askling J; Dixon WG; Klareskog L; Silman AJ; Symmons DPM
Editorial comment: JOURNAL OF MOLECULAR MEDICINE-JMM. 2009;87(4):357-362

On the origins of complex immune-mediated disease: the example of rheumatoid arthritis

Klareskog L; Wedren S; Alfredsson L
Review: LANCET. 2009;373(9664):659-672

Rheumatoid arthritis

Klareskog L; Catrina AI; Paget S
Letter: PSYCHOTHERAPY AND PSYCHOSOMATICS. 2009;78(3):193-194

Psychosocial Stress at Work and the Risk of Developing Rheumatoid Arthritis: Results from the Swedish EIRA Study

Bengtsson C; Theorell T; Klareskog L; Alfredsson L
Letter: ARTHRITIS & RHEUMATOLOGY. 2008;59(11):1685

Effects of disease-modifying antirheumatic drug treatment on the expression of RANKL and osteoprotegerin in synovial tissue: comment on the article by Haynes et al

Catrina AI; Klareskog L
Editorial comment: ARTHRITIS & RHEUMATOLOGY. 2008;58(9):2591-2597

Genome-wide single-nucleotide polymorphism studies in rheumatology: Hype or hope?

Mil AHMVDH-V; Padyukov L; Toes RM; Klareskog L; Huizinga TWJ
Review: CURRENT OPINION IN RHEUMATOLOGY. 2008;20(3):300-305

Antibodies to citrullinated proteins in arthritis:: pathology and promise

Klareskog L; Widhe M; Hermansson M; Ronnelid J
Review: ANNUAL REVIEW OF IMMUNOLOGY. 2008;26:651-675

Immunity to citrullinated proteins in rheumatoid arthritis

Klareskog L; Roennelid J; Lundberg K; Padyukov L; Adfredsson L
Review: PHARMACOLOGY & THERAPEUTICS. 2008;117(2):244-279

Tumor necrosis factor antagonist mechanisms of action: A comprehensive review

Tracey D; Klareskog L; Sasso EH; Salfeld JG; Tak PP
Editorial comment: ARTHRITIS & RHEUMATOLOGY. 2008;58(1):2-4

Antiinflammatory therapy for rheumatoid arthritis?

Cohen IR; Klareskog L
Letter: ARTHRITIS & RHEUMATOLOGY. 2007;56(3):1031-1032

Reply to letter by Yazici and Yazici commenting on the two-year report on the Trial of Etanercept and Methotrexate with Radiographic and Patient Outcomes

van der Heijde D; Klareskog L
Review: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(2):143-150

Consensus statement on the use of rituximab in patients with rheumatoid arthritis

Smolen JS; Keystone EC; Emery P; Breedveld FC; Betteridge N; Burmester GR; Dougados M; Ferraccioli G; Jaeger U; Klareskog L; Kvien TK; Martin-Mola E; Pavelka K
Review: CURRENT OPINION IN RHEUMATOLOGY. 2007;19(1):49-54

Smoking as a trigger for inflammatory rheumatic diseases

Klareskog L; Padyukov L; Alfredsson L
Review: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(1):34-45

EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)

Combe B; Landewe R; Lukas C; Bolosiu HD; Breedveld F; Dougados M; Emery P; Ferraccioli G; Hazes JMW; Klareskog L; Machold K; Martin-Mola E; Nielsen H; Silman A; Smolen J; Yazici H
Review: CURRENT OPINION IN IMMUNOLOGY. 2006;18(6):650-655

Genes, environment and immunity in the development of rheumatoid arthritis

Klareskog L; Padyukov L; Ronnelid J; Alfredsson L
Review: NATURE CLINICAL PRACTICE RHEUMATOLOGY. 2006;2(8):425-433

Mechanisms of disease: genetic susceptibility and environmental triggers in the development of rheumatoid arthritis

Klareskog L; Padyukov L; Lorentzen J; Alfredsson L
Review: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(6):707-712

Swedish registers to examine drug safety and clinical issues in RA

Askling J; Fored CM; Geborek P; Jacobsson LTH; van Vollenhoven R; Feltelius N; Lindblad S; Klareskog L
Meeting abstract: CLINICAL IMMUNOLOGY. 2006;119:S63

Increased Baff levels after rituximab-induced B-cell depletion in SLE patients.

Wallerskog T; Zhou W; Wohren-Herlenius M; Klareskog L; Malmstrom V; Trollmo C
Letter: ARTHRITIS & RHEUMATOLOGY. 2005;52(11):3676-3678

The interaction of smoking and the HLA-DRB1 shared epitope in rheumatoid factor-positive rheumatoid arthritis:: comment on the article by Padyukov et al -: Reply

Padyukov L; Alfredsson L; Källberg H; Bengtsson C; Klareskog L
Published conference paper: ANNALS OF THE RHEUMATIC DISEASES. 2005;64(Suppl 4):iv2-i14

Updated consensus statement on biological agents, specifically tumour necrosis factor α (TNFα) blocking agents and interleukin-1 receptor antagonist (IL-1ra), for the treatment of rheumatic diseases, 2005

Furst DE; Breedveld FC; Kalden JR; Smolen JS; Burmester GR; Bijlsma JWJ; Dougados M; Emery P; Keystone EC; Klareskog L; Mease PJ
Editorial comment: ARTHRITIS & RHEUMATOLOGY. 2005;52(4):991-994

The treatment of rheumatoid arthritis: Getting better all the time?

van Vollenhoven RF; Klareskog L
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2005;6(1):65-66

Lipid-peroxidation is enhanced in sle patients and associated with arterial and renal disease manifestations

Frostegard J; Svenungsson E; Wu R; Gunnarsson I; Lundberg I; Klareskog L; Hörkkö S; Witztum J
Review: ARTHRITIS RESEARCH & THERAPY. 2005;7(Suppl 2):S15-S20

Modulating co-stimulation:: a rational strategy in the treatment of rheumatoid arthritis?

Malmström V; Trollmo C; Klareskog L
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:S34

Effects of anti-rheumatic treatments on the prostaglandin E₂ biosynthetic pathway in synovial tissue and synovial fluid cells from patients with rheumatoid arthritis

Korotkova M; Westman M; Gheorghe KR; af Klint E; Trollmo C; Ulfgren A-K; Klareskog L; Jakobsson P-J
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:S31-S32

Distinct patterns of RANKL/osteoprotegerin system modulation through anti-tumour necrosis factor and corticosteroid therapy in rheumatoid arthritis synovium

Catrina AI; Makrygiannakis D; af Klint E; Catrina SB; Ernestam S; Klareskog L; Ulfgren AK
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:p116-S43

Patterns of gene expression in rheumatoid arthritis synovial tissue: inter-patient variability greater then intra-patient variability in a small study

Lindberg J; af Klint E; Stark A; Andersson T; Nilsson P; Klareskog L; Ulfgren A; Lundeberg J
Published conference paper: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(Suppl 2):ii28-ii31

What precedes development of rheumatoid arthritis?

Klareskog L; Alredsson L; Rantapää-Dahlqvist S; Berglin E; Stolt P; Padyukov L
Published conference paper: ANNALS OF THE RHEUMATIC DISEASES. 2004;63(Suppl 2):2-12

Updated consensus statement on biological agents, specifically tumour necrosis factor α (TNFα) blocking agents and interleukin-1 receptor antagonist (IL-1ra), for the treatment of rheumatic diseases, 2004

Furst DE; Breedveld FC; Kalden JR; Smolen JS; Burmester GR; Bijlsma JWJ; Dougados M; Emery P; Keystone EC; Klareskog L; Mease PJ
Editorial comment: LANCET. 2004;363(9426):2011-2012

Statins in rheumatoid arthritis - two birds with one stone?

Klareskog L; Hamsten A
Letter: LANCET. 2004;363(9422):1733

Etanercept and methotrexate in rheumatoid arthritis - Authors' reply

Klareskog L
Review: CURRENT OPINION IN RHEUMATOLOGY. 2004;16(3):254-261

Rheumatoid arthritis and malignant lymphomas

Baecklund E; Askling J; Rosenquist R; Ekbom A; Klareskog L
Editorial comment: BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY. 2004;18(1):1-5

How is clinical progress achieved?

Klareskog L; Lindblad S
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S32-S33

Effects of anti-rheumatic treatments on expression of microsomal prostaglandin E synthase-1 in rheumatoid arthritis synovium

Korotkova M; Westman M; af Klint E; Ulfgren AK; Klareskog L; Jakobsson PJ
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S30-S31

Prediagnosis radiological progression in rheumatoid arthritis: a novel tool to study the effects of early DMARD therapy

Wick MC; Weiss RJ; Klareskog L; van Vollenhoven RF
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S10

Intra-articular steroid treatment reduces synovial HMGB1 but not IL-1 expression in chronic arthritis

Grundtman C; Klint EA; Andersson U; Klareskog L; Ulfgren A
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S14-S15

CD25brightCD4⁺ regulatory T cells accumulate in inflamed joints of patients with chronic rheumatic disease

Cao D; van Vollenhoven R; Klareskog L; Trollmo C; Malmström V
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:53-S18

Differential gene expression and protein expression levels of MMP and TIMP molecules in response to glucocorticoid treatment in arthritic patients

Andersson T; af Klint E; Strobel S; Andersson U; Stark A; Gelinas R; Lundeberg J; Klareskog L; Ulfgren AK
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S9

Anti-tumour necrosis factor therapy modulates the OPG/OPGL system in rheumatoid arthritis synovium

Catrina AI; Ernestam S; Klint EA; Klareskog L; Ulfgren AK
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2004;6:S7

Citrullinated proteins in arthritis: presence in joints and effects on immunogenicity

Lundberg K; Nijenhuis S; Vossenaar E; Klareskog L; van Venrooij WJ; Harris HE
Published conference paper: ANNALS OF THE RHEUMATIC DISEASES. 2003;61(Suppl 2):2-7

Updated consensus statement on biological agents for the treatment of rheumatoid arthritis and other rheumatic diseases (May 2002)

Furst DE; Breedveld FC; Kalden JR; Smolen JS; Antoni CE; Bijlsma JWJ; Burmester GR; Cronstein B; Keystone EC; Kavanaugh A; Klareskog L
Review: ANNALS OF THE RHEUMATIC DISEASES. 2002;62(Suppl 2):2-9

Updated consensus statement on biological agents for the treatment of rheumatoid arthritis and other immune mediated inflammatory diseases (May 2003)

Furst DE; Breedveld FC; Kalden JR; Smolen JS; Burmester GR; Dougados M; Emery P; Gibofsky A; Kavenaugh AF; Keystone EC; Klareskog L; Russell AS; van de Putte LBA; Weisman MH
Review: ARTHRITIS RESEARCH & THERAPY. 2002;4(Suppl 3):S31-S36

Genes and environment in arthritis: can RA be prevented?

Klareskog L; Lorentzen J; Padyukov L; Alfredsson L
Review: LAKARTIDNINGEN. 2001;98(8):828-831

[Blockade of TNFalpha--new therapeutic principle in severe rheumatoid arthritis].

Larsson P; Bratt J; Harju A; van Vollenhoven R; Klareskog L
Review: LAKARTIDNINGEN. 2000;97(48):5628-5632

[New drugs against rheumatoid arthritis. Improved treatment options place new demands on health care organization].

Klareskog L; Hafström I; Saxne T; Hedin PJ
Review: ANNALS OF THE RHEUMATIC DISEASES. 2000;59(7):506-510

Synovial biopsy in arthritis research: five years of concerted European collaboration

Bresnihan B; Tak PP; Emery P; Klareskog L; Breedveld F
Review: ARTHRITIS RESEARCH & THERAPY. 2000;2(1):75-84

Interferon-γ production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1*0401 and HLA-DQ8

Berg L; Rönnelid J; Sanjeevi CB; Lampa J; Klareskog L
Review: CURRENT OPINION IN IMMUNOLOGY. 1999;11(6):657-662

Rheumatoid arthritis and its animal models:: the role of TNF-α and the possible absence of specific immune reactions

Klareskog L; McDevitt H
Published conference paper: JOURNAL OF AUTOIMMUNITY. 1999;13(1):137-141

A comparison of genome-scans performed in multicase families with systemic lupus erythematosus from different population groups

Johanneson N; Steinsson K; Lindqvist AK; Kristjánsdóttir H; Gröndal G; Sandino S; Tjernström F; Sturfelt G; Granados-Arriola J; Alcocer-Varela J; Lundberg I; Jonasson I; Truedsson L; Svenungssons E; Klareskog L; Alarcón-Segovia D; Gyllensten UB; Alarcón-Riquelme ME
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1999;31(3):1594-1596

Susceptibility of rats to homologous collagen-induced arthritis depends on MHC genes in the class II region

Mattsson L; Klareskog L; Lorentzen JC
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1997;29(3):1692-1693

Comparative susceptibility of DA, LEW, and LEW.1AV1 rats to arthritis induced with different arthritogens: Mineral oil, mycobacteria, muramyl dipeptide, avridine and rat collagen type II

Lorentzen JC; Klareskog L
Published conference paper: SURGERY. 1995;118(6):1055-1062

EXPRESSION AND FUNCTION OF A CD3-LIKE MOLECULE ON NORMAL AND ABNORMAL HUMAN PARATHYROID CELLS

HELLMAN P; JUHLIN C; KARLSSONPARRA A; KLARESKOG L; RIDEFELT P; RASTAD J; AKERSTROM G
Review: JOURNAL OF INTERNAL MEDICINE. 1995;238(3):191-206

IMMUNOPATHOGENESIS AND IMMUNOTHERAPY IN RHEUMATOID-ARTHRITIS - AN AREA IN TRANSITION

KLARESKOG L; RONNELID J; HOLM G
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1995;756:225-226

RESTRICTED T-CELL RECEPTOR USAGE IN DA RATS DURING EARLY COLLAGEN-INDUCED ARTHRITIS

ERLANDSSON H; MUSSENER A; KLARESKOG L; GOLD DP
Published conference paper: TRANSPLANTATION PROCEEDINGS. 1995;27(2):1532-1534

SUSCEPTIBILITY TO OIL-INDUCED ARTHRITIS IN THE DA RAT IS DETERMINED BY MHC AND NON-MHC GENES

LORENTZEN JC; OLSSON T; KLARESKOG L
Other: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 1995;:111-112

SYNOVIAL LINING CELL MACROPHAGES - ROLE IN LOCALIZATION AND EXPRESSION OF INFLAMMATION - DISCUSSION

HACK CE; BURMESTER GR; MAINI RN; PETER HH; FELTKAMP TEW; VANLENT P; SCHUMACHER HR; JASIN HE; KINNE R; ZVAIFLER NJ; GLANT TT; VANDENBERG WB; KLARESKOG L; HALLMAN R
Other: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 1995;:187-188

SPECIFIC IMMUNITY - ROLE IN CHRONIC ARTHRITIS AND MODELS, INCLUDING RHEUMATOID-FACTOR, EXCLUDING CARTILAGE ANTIGENS - DISCUSSION

AARDEN L; BLAKE D; ZVAIFLER NJ; VANEDEN W; MAINI RN; KLARESKOG L; MELCHERS I; GLANT TT; FELTKAMP TEW; EMMRICH F; EIBEL H; BREEDVELD FC; VEYS EM; HERMANN E; TOIVANEN; VERWEIJ; VANDEPUTTE LBA; KINNE R
Other: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 1995;:63

CARTILAGE - DISCUSSION

GLANT TT; VANDENBERG WB; ZVAIFLER NJ; EMMRICH F; MAINI RN; MELCHERS I; BURMESTER GR; KLARESKOG L; BREEDVELD FC; KINNE R; JASIN HE; HERMANN E; BLAKE D
Published conference paper: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, SUPPLEMENT. 1995;101:57-61

LOCAL VERSUS SYSTEMIC IMMUNOREACTIVITY TO COLLAGEN AND THE COLLAGE-LIKE REGION OF C1Q IN RHEUMATOID-ARTHRITIS AND SLE

RONNELID J; KLARESKOG L
Published conference paper: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, SUPPLEMENT. 1995;101:179-181

ROLE OF ADJUVANTS IN TURNING AUTOIMMUNITY INTO AUTOIMMUNE-DISEASE

KLEINAU S; LORENTZEN J; KLARESKOG L
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