Anna Wredenberg

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About me

Professor and PI in mitochondrial biology and consultant in clinical genetics/metabolic diseases.

Articles

Article: JCI INSIGHT. 2024;9(20):e178645
Quantitative proteomics of patient fibroblasts reveal biomarkers and diagnostic signatures of mitochondrial disease
Correia SP; Moedas MF; Taylor LS; Naess K; Lim AZ; McFarland R; Kazior Z; Rumyantseva A; Wibom R; Engvall M; Bruhn H; Lesko N; Vegvari A; Kall L; Trost M; Alston CL; Freyer C; Taylor RW; Wedell A; Wredenberg A
Article: NPJ PARKINSON'S DISEASE. 2024;10(1):93
PARKIN is not required to sustain OXPHOS function in adult mammalian tissues
Filograna R; Gerlach J; Choi H-N; Rigoni G; Barbaro M; Oscarson M; Lee S; Tiklova K; Ringner M; Koolmeister C; Wibom R; Riggare S; Nennesmo I; Perlmann T; Wredenberg A; Wedell A; Motori E; Svenningsson P; Larsson N-G
Article: HUMAN MUTATION. 2024;2024:1-16
Novel Synonymous and Deep Intronic Variants Causing Primary and Secondary Pyruvate Dehydrogenase Complex Deficiency
Bruhn H; Naess K; Ygberg S; Pena-Perez L; Lesko N; Wibom R; Freyer C; Stranneheim H; Wedell A; Wredenberg A
Article: NEUROLOGY: GENETICS. 2023;9(6):e200100
Ataxia Syndrome With Hearing Loss and Nephronophthisis Associated With a Novel Homozygous Variant in XPNPEP3
Ben-Shabat I; Kvarnung M; Sperker W; Bruhn H; Wredenberg A; Wibom R; Nennesmo I; Engvall M; Paucar M
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR BASIS OF DISEASE. 2023;1869(7):166786
The disease-causing mutation p.F907I reveals a novel pathogenic mechanism for POL?-related diseases
Erdinc D; Macao B; Valenzuela S; Lesko N; Naess K; Peter B; Bruhn H; Wedell A; Wredenberg A; Falkenberg M
Article: JCI INSIGHT. 2023;8(17):e167656
Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations
Zhang J; Koolmeister C; Han J; Filograna R; Hanke L; Adori M; Sheward DJ; Teifel S; Gopalakrishna S; Shao Q; Liu Y; Zhu K; Harris RA; Mcinerney G; Murrell B; Aoun M; Baeckdahl L; Holmdahl R; Pekalski M; Wedell A; Engvall M; Wredenberg A; Hedestam GBK; Dopico XC; Rorbach J
Article: BRAIN. 2023;146(4):1357-1372
ATP6V0C variants impair V-ATPase function causing a neurodevelopmental disorder often associated with epilepsy
Mattison KA; Tossing G; Mulroe F; Simmons C; Butler KM; Schreiber A; Alsadah A; Neilson DE; Naess K; Wedell A; Wredenberg A; Sorlin A; McCann E; Burghel GJ; Menendez B; Hoganson GE; Botto LD; Filloux FM; Aledo-Serrano A; Gil-Nagel A; Tatton-Brown K; Verbeek NE; van der Zwaag B; Aleck KA; Fazenbaker AC; Balciuniene J; Dubbs HA; Marsh ED; Garber K; Ek J; Duno M; Hoei-Hansen CE; Deardorff MA; Raca G; Quindipan C; van Hirtum-Das M; Breckpot J; Hammer TB; Moller RS; Whitney A; Douglas AGL; Kharbanda M; Brunetti-Pierri N; Morleo M; Nigro V; May HJ; Tao JX; Argilli E; Sherr EH; Dobyns WB; Baines RA; Warwicker J; Parker JA; Banka S; Campeau PM; Escayg A
Article: BIOMEDICINES. 2022;10(12):3171
A Missense Variant in PDK1 Associated with Severe Neurodevelopmental Delay and Epilepsy
Vaz R; Wincent J; Elfissi N; Rosengren Forsblad K; Pettersson M; Naess K; Wedell A; Wredenberg A; Lindstrand A; Ygberg S
Article: NATURE COMMUNICATIONS. 2022;13(1):5750
ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing
Clemente P; Calvo-Garrido J; Pearce SF; Schober FA; Shigematsu M; Siira SJ; Laine I; Spahr H; Steinmetzger C; Petzold K; Kirino Y; Wibom R; Rackham O; Filipovska A; Rorbach J; Freyer C; Wredenberg A
Article: NUCLEIC ACIDS RESEARCH (NAR). 2022;50(15):8749-8766
Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion
Misic J; Milenkovic D; Al-Behadili A; Xie X; Jiang M; Jiang S; Filograna R; Koolmeister C; Siira SJ; Jenninger L; Filipovska A; Clausen AR; Caporali L; Valentino ML; La Morgia C; Carelli V; Nicholls TJ; Wredenberg A; Falkenberg M; Larsson N-G
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2022;109(8):1421-1435
Bi-allelic loss-of-function variants in PPFIBP1 cause a neurodevelopmental disorder with microcephaly, epilepsy, and periventricular calcifications
Rosenhahn E; O'Brien TJ; Zaki MS; Sorge I; Wieczorek D; Rostasy K; Vitobello A; Nambot S; Alkuraya FS; Hashem MO; Alhashem A; Tabarki B; Alamri AS; Al Safar AH; Bubshait DK; Alahmady NF; Gleeson JG; Abdel-Hamid MS; Lesko N; Ygberg S; Correia SP; Wredenberg A; Alavi S; Seyedhassani SM; Nasab ME; Hussien H; Omar TEI; Harzallah I; Touraine R; Tajsharghi H; Morsy H; Houlden H; Shahrooei M; Ghavideldarestani M; Abdel-Salam GMH; Torella A; Zanobio M; Terrone G; Brunetti-Pierri N; Omrani A; Hentschel J; Lemke JR; Sticht H; Abou Jamra R; Brown AEX; Maroofian R; Platzer K
Article: HUMAN MOLECULAR GENETICS. 2022;31(12):2049-2062
Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease
Schober FA; Tang JX; Sergeant K; Moedas MF; Zierz CM; Moore D; Smith C; Lewis D; Guha N; Hopton S; Falkous G; Lam A; Pyle A; Poulton J; Gorman GS; Taylor RW; Freyer C; Wredenberg A
Article: STAR PROTOCOLS. 2021;2(2):100528
Protocol for the derivation, culturing, and differentiation of human iPS-cell-derived neuroepithelial stem cells to study neural differentiation in vitro
Calvo-Garrido J; Winn D; Maffezzini C; Wedell A; Freyer C; Falk A; Wredenberg A
Article: HUMAN MUTATION. 2021;42(4):378-384
Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7
Correia SP; Moedas MF; Naess K; Bruhn H; Maffezzini C; Calvo-Garrido J; Lesko N; Wibom R; Schober FA; Jemt A; Stranneheim H; Freyer C; Wedell A; Wredenberg A
Article: NEUROLOGY: GENETICS. 2021;7(2):e566
Novel Mutation m.10372A>G in MT-ND3 Causing Sensorimotor Axonal Polyneuropathy
Bruhn H; Samuelsson K; Schober FA; Engvall M; Lesko N; Wibom R; Nennesmo I; Calvo-Garrido J; Press R; Stranneheim H; Freyer C; Wedell A; Wredenberg A
Article: GENOME MEDICINE. 2021;13(1):40
Integration of whole genome sequencing into a healthcare setting: high diagnostic rates across multiple clinical entities in 3219 rare disease patients
Stranneheim H; Lagerstedt-Robinson K; Magnusson M; Kvarnung M; Nilsson D; Lesko N; Engvall M; Anderlid B-M; Arnell H; Johansson CB; Barbaro M; Bjorck E; Bruhn H; Eisfeldt J; Freyer C; Grigelioniene G; Gustavsson P; Hammarsjo A; Hellstrom-Pigg M; Iwarsson E; Jemt A; Laaksonen M; Enoksson SL; Malmgren H; Naess K; Nordenskjold M; Oscarson M; Pettersson M; Rasi C; Rosenbaum A; Sahlin E; Sardh E; Stodberg T; Tesi B; Tham E; Thonberg H; Tohonen V; von Dobeln U; Vassiliou D; Vonlanthen S; Wikstrom A-C; Wincent J; Winqvist O; Wredenberg A; Ygberg S; Zetterstrom RH; Marits P; Soller MJ; Nordgren A; Wirta V; Lindstrand A; Wedell A
Article: SCIENCE ADVANCES. 2021;7(8):eabf0717
The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters
Schober FA; Moore D; Atanassov I; Moedas MF; Clemente P; Vegvari A; El Fissi N; Filograna R; Bucher A-L; Hinze Y; The M; Hedman E; Chernogubova E; Begzati A; Wibom R; Jain M; Nilsson R; Kall L; Wedell A; Freyer C; Wredenberg A
Article: NUCLEIC ACIDS RESEARCH (NAR). 2021;49(1):354-370
Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly
Cipullo M; Pearce SF; Sanchez IGL; Gopalakrishna S; Kruger A; Schober F; Busch JD; Li X; Wredenberg A; Atanassov I; Rorbach J
Article: METHODS IN MOLECULAR BIOLOGY. 2021;2192:75-87
Quantitative Proteomics in Drosophila with Holidic Stable-Isotope Labeling of Amino Acids in Fruit Flies (SILAF).
Schober FA; Atanassov I; Freyer C; Wredenberg A
Article: FRONTIERS IN NEUROLOGY. 2021;12:652590
Case Report: A Novel Mutation in the Mitochondrial MT-ND5 Gene Is Associated With Leber Hereditary Optic Neuropathy (LHON)
Engvall M; Kawasaki A; Carelli V; Wibom R; Bruhn H; Lesko N; Schober FA; Wredenberg A; Wedell A; Traisk F
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100065
Stable Isotope Labeling of Amino Acids in Flies (SILAF) Reveals Differential Phosphorylation of Mitochondrial Proteins Upon Loss of OXPHOS Subunits
Rosenberger FA; Atanassov I; Moore D; Calvo-Garrido J; Moedas MF; Wedell A; Freyer C; Wredenberg A
Article: JOURNAL OF PEDIATRICS. 2021;228:240-251.e2
Clinical Presentation, Genetic Etiology, and Coenzyme Q10 Levels in 55 Children with Combined Enzyme Deficiencies of the Mitochondrial Respiratory Chain
Naess K; Bruhn H; Stranneheim H; Freyer C; Wibom R; Mourier A; Engvall M; Nennesmo I; Lesko N; Wredenberg A; Wedell A; von Dobeln U
Article: NEUROLOGY: GENETICS. 2020;6(4):e478
SLC12A2 mutations cause NKCC1 deficiency with encephalopathy and impaired secretory epithelia
Stodberg T; Magnusson M; Lesko N; Wredenberg A; Martin Munoz D; Stranneheim H; Wedell A
Article: EMBO MOLECULAR MEDICINE. 2020;12(7):e11659
FBXL4 deficiency increases mitochondrial removal by autophagy
Alsina D; Lytovchenko O; Schab A; Atanassov I; Schober FA; Jiang M; Koolmeister C; Wedell A; Taylor RW; Wredenberg A; Larsson N-G
Article: NUCLEIC ACIDS RESEARCH (NAR). 2019;47(17):9386-9399
C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis
Gopalakrishna S; Pearce SF; Dinan AM; Schober FA; Cipullo M; Spahr H; Khawaja A; Maffezzini C; Freyer C; Wredenberg A; Atanassov I; Firth AE; Rorbach J
Article: PLOS GENETICS. 2019;15(7):e1008240
Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo
Pajak A; Laine I; Clemente P; El-Fissi N; Schober FA; Maffezzini C; Calvo-Garrido J; Wibom R; Filograna R; Dhir A; Wedell A; Freyer C; Wredenberg A
Article: MOLECULAR GENETICS & GENOMIC MEDICINE. 2019;7(6):e654
Mutations in the mitochondrial tryptophanyl-tRNA synthetase cause growth retardation and progressive leukoencephalopathy
Maffezzini C; Laine I; Dallabona C; Clemente P; Calvo-Garrido J; Wibom R; Naess K; Barbaro M; Falk A; Donnini C; Freyer C; Wredenberg A; Wedell A
Article: STEM CELL REPORTS. 2019;12(4):696-711
SQSTM1/p62-Directed Metabolic Reprogramming Is Essential for Normal Neurodifferentiation
Calvo-Garrido J; Maffezzini C; Schober FA; Clemente P; Uhlin E; Kele M; Stranneheim H; Lesko N; Bruhn H; Svenningsson P; Falk A; Wedell A; Freyer C; Wredenberg A
Article: SCIENCE ADVANCES. 2019;5(4):eaav9824
Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse
Filograna R; Koolmeister C; Upadhyay M; Pajak A; Clemente P; Wibom R; Simard ML; Wredenberg A; Freyer C; Stewart JB; Larsson NG
Article: DIABETES. 2019;68(4):709-723
Absence of TXNIP in Humans Leads to Lactic Acidosis and Low Serum Methionine Linked to Deficient Respiration on Pyruvate
Katsu-Jimenez Y; Vazquez-Calvo C; Maffezzini C; Halldin M; Peng X; Freyer C; Wredenberg A; Gimenez-Cassina A; Wedell A; Arner ESJ
Article: NATURE COMMUNICATIONS. 2019;10(1):1396
Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions
Olive M; Engvall M; Ravenscroft G; Cabrera-Serrano M; Jiao H; Bortolotti CA; Pignataro M; Lambrughi M; Jiang H; Forrest ARR; Benseny-Cases N; Hofbauer S; Obinger C; Battistuzzi G; Bellei M; Borsari M; Di Rocco G; Viola HM; Hoo LC; Cladera J; Lagerstedt-Robinson K; Xiang F; Wredenberg A; Miralles F; Jose Baiges J; Malfatti E; Romero NB; Streichenberger N; Via C; Claeys KG; Straathof CSM; Goris A; Freyer C; Lammens M; Bassez G; Kere J; Clemente P; Sejersen T; Udd B; Vidal N; Ferrer I; Edstrom L; Wedell A; Laing NG
Article: NATURE COMMUNICATIONS. 2018;9(1):3966
RNA modification landscape of the human mitochondrial tRNA^LYs regulates protein synthesis
Richter U; Evans ME; Clark WC; Marttinen P; Shoubridge EA; Suomalainen A; Wredenberg A; Wedell A; Pan T; Battersby BJ
Article: MOLECULAR GENETICS AND METABOLISM. 2017;121(3):216-223
Detection of 6-demethoxyubiquinone in CoQ₁₀ deficiency disorders: Insights into enzyme interactions and identification of potential therapeutics
Herebian D; Seibt A; Smits SHJ; Buenning G; Freyer C; Prokisch H; Karall D; Wredenberg A; Wedell A; Lopez LC; Mayatepek E; Distelmaier F
Article: HUMAN MOLECULAR GENETICS. 2017;26(13):2515-2525
A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma
Siibak T; Clemente P; Bratic A; Bruhn H; Kauppila TES; Macao B; Schober FA; Lesko N; Wibom R; Naess K; Nennesmo I; Wedell A; Peter B; Freyer C; Falkenberg M; Wredenberg A
Article: ORPHANET JOURNAL OF RARE DISEASES. 2017;12(1):73
Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model
Tegelberg S; Tomasic N; Kallijarvi J; Purhonen J; Elmer E; Lindberg E; Nord DG; Soller M; Lesko N; Wedell A; Bruhn H; Freyer C; Stranneheim H; Wibom R; Nennesmo I; Wredenberg A; Eklund EA; Fellman V
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2016;99(3):735-743
Absence of the Autophagy Adaptor SQSTM1/p62 Causes Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy
Haack TB; Ignatius E; Calvo-Garrido J; Iuso A; Isohanni P; Maffezzini C; Lonnqvist T; Suomalainen A; Gorza M; Kremer LS; Graf E; Hartig M; Berutti R; Paucar M; Svenningsson P; Stranneheim H; Brandberg G; Wedell A; Kurian MA; Hayflick SA; Venco P; Tiranti V; Strom TM; Dichgans M; Horvath R; Holinski-Feder E; Freyer C; Meitinger T; Prokisch H; Senderek J; Wredenberg A; Carroll CJ; Klopstock T
Article: PLOS GENETICS. 2016;12(5):e1006028
Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation
Bratic A; Clemente P; Calvo-Garrido J; Maffezzini C; Felser A; Wibom R; Wedell A; Freyer C; Wredenberg A
Article: HUMAN MOLECULAR GENETICS. 2015;24(23):6580-6587
Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy
Gineste C; Hernandez A; Ivarsson N; Cheng AJ; Naess K; Wibom R; Lesko N; Bruhn H; Wedell A; Freyer C; Zhang S-J; Carlstrom M; Lanner JT; Andersson DC; Bruton JD; Wredenberg A; Westerblad H
Article: NATURE COMMUNICATIONS. 2015;6:8808
Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies
Bratic A; Kauppila TES; Macao B; Groenke S; Siibak T; Stewart JB; Baggio F; Dols J; Partridge L; Falkenberg M; Wredenberg A; Larsson N-G
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2015;97(5):761-768
Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26
Kishita Y; Pajak A; Bolar NA; Marobbio CMT; Maffezzini C; Miniero DV; Monne M; Kohda M; Stranneheim H; Murayama K; Naess K; Lesko N; Bruhn H; Mourier A; Wibom R; Nennesmo I; Jespers A; Goyaert P; Ohtake A; Van Laer L; Loeys BL; Freyer C; Palmieri F; Wredenberg A; Okazaki Y; Wedell A
Article: JOURNAL OF MEDICAL GENETICS. 2015;52(11):779-783
Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4-dihydroxybensoic acid
Freyer C; Stranneheim H; Naess K; Mourier A; Felser A; Maffezzini C; Lesko N; Bruhn H; Engvall M; Wibom R; Barbaro M; Hinze Y; Magnusson M; Andeer R; Zetterstrom RH; von Dobeln U; Wredenberg A; Wedell A
Article: NUCLEIC ACIDS RESEARCH (NAR). 2015;43(15):7398-7413
SUV3 helicase is required for correct processing of mitochondrial transcripts
Clemente P; Pajak A; Laine I; Wibom R; Wedell A; Freyer C; Wredenberg A
Article: BMC GENOMICS. 2014;15(1):1090
Rapid pulsed whole genome sequencing for comprehensive acute diagnostics of inborn errors of metabolism
Stranneheim H; Engvall M; Naess K; Lesko N; Larsson P; Dahlberg M; Andeer R; Wredenberg A; Freyer C; Barbaro M; Bruhn H; Emahazion T; Magnusson M; Wibom R; Zetterstrom RH; Wirta V; von Dobeln U; Wedell A
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2014;95(3):285-293
Neu-Laxova Syndrome Is a Heterogeneous Metabolic Disorder Caused by Defects in Enzymes of the L-Serine Biosynthesis Pathway
Acuna-Hidalgo R; Schanze D; Kariminejad A; Nordgren A; Kariminejad MH; Conner P; Grigelioniene G; Nilsson D; Nordenskjold M; Wedell A; Freyer C; Wredenberg A; Wieczorek D; Gillessen-Kaesbach G; Kayserili H; Elcioglu N; Ghaderi-Sohi S; Goodarzi P; Setayesh H; van de Vorst M; Steehouwer M; Pfundt R; Krabichler B; Curry C; MacKenzie MG; Boycott KM; Gilissen C; Janecke AR; Hoischen A; Zenker M
Article: PLOS GENETICS. 2013;9(1):e1003178
MTERF3 Regulates Mitochondrial Ribosome Biogenesis in Invertebrates and Mammals
Wredenberg A; Lagouge M; Bratic A; Metodiev MD; Spahr H; Mourier A; Freyer C; Ruzzenente B; Tain L; Groenke S; Baggio F; Kukat C; Kremmer E; Wibom R; Polosa PL; Habermann B; Partridge L; Park CB; Larsson N-G
Article: EMBO JOURNAL. 2012;31(2):443-456
LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs
Ruzzenente B; Metodiev MD; Wredenberg A; Bratic A; Park CB; Camara Y; Milenkovic D; Zickermann V; Wibom R; Hultenby K; Erdjument-Bromage H; Tempst P; Brandt U; Stewart JB; Gustafsson CM; Larsson N-G
Article: PLOS GENETICS. 2011;7(10):e1002324
The Bicoid Stability Factor Controls Polyadenylation and Expression of Specific Mitochondrial mRNAs in Drosophila melanogaster
Bratic A; Wredenberg A; Groenke S; Stewart JB; Mourier A; Ruzzenente B; Kukat C; Wibom R; Habermann B; Partridge L; Larsson N-G
Article: CELL METABOLISM. 2009;10(2):131-138
Random Point Mutations with Major Effects on Protein-Coding Genes Are the Driving Force behind Premature Aging in mtDNA Mutator Mice
Edgar D; Shabalina I; Camara Y; Wredenberg A; Calvaruso MA; Nijtmans L; Nedergaard J; Cannon B; Larsson N-G; Trifunovic A
Article: HUMAN MOLECULAR GENETICS. 2009;18(2):278-288
Increased mitochondrial Ca²⁺ and decreased sarcoplasmic reticulum Ca²⁺ in mitochondrial myopathy
Aydin J; Andersson DC; Hanninen SL; Wredenberg A; Tavi P; Park CB; Larsson N-G; Bruton JD; Westerblad H
Article: PLOS BIOLOGY. 2008;6(1):63-71
Strong purifying selection in transmission of mammalian mitochondrial DNA
Stewart JB; Freyer C; Elson JL; Wredenberg A; Cansu Z; Trifunovic A; Larsson N-G
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;350(1):202-207
Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance
Wredenberg A; Freyer C; Sandstrom ME; Katz A; Wibom R; Westerblad H; Larsson N-G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(50):17993-17998
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
Trifunovic A; Hansson A; Wredenberg A; Rovio AT; Dufour E; Khvorostov I; Spelbrink JN; Wibom R; Jacobs HT; Larsson NG
Article: NATURE. 2004;429(6990):417-423
Premature ageing in mice expressing defective mitochondrial DNA polymerase
Trifunovic A; Wredenberg A; Falkenberg M; Spelbrink JN; Rovio AT; Bruder CE; Bohlooly-Y M; Gidlöf S; Oldfors A; Wibom R; Törnell J; Jacobs HT; Larsson NG
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(23):15066-15071
Increased mitochondrial mass in mitochondrial myopathy mice
Wredenberg A; Wibom R; Wilhelmsson H; Graff C; Wiener HH; Burden SJ; Oldfors A; Westerblad H; Larsson NG
Article: PRENATAL DIAGNOSIS. 2000;20(5):426-431
Complex genetic counselling and prenatal analysis in a woman with external ophthalmoplegia and deleted mtDNA
Graff C; Wredenberg A; Silva JP; Bui TH; Borg K; Larsson NG
Article: JOURNAL OF REHABILITATION MEDICINE. 1999;31(1):9-16
Effects of high resistance training in patients with myotonic dystrophy
Tollbäck A; Eriksson S; Wredenberg A; Jenner G; Vargas R; Borg K; Ansved T
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Editorial comment: STEM CELLS TRANSLATIONAL MEDICINE. 2024;13(6):505-514
Human In Vitro Models of Neuroenergetics and Neurometabolic Disturbances: Current Advances and Clinical Perspectives
Rogal J; Zamproni LN; Nikolakopoulou P; Ygberg S; Wedell A; Wredenberg A; Herland A
Review: HUMAN MOLECULAR GENETICS. 2024;33(R1):R19-R25
The molecular machinery for maturation of primary mtDNA transcripts
Vuckovic A; Freyer C; Wredenberg A; Hillen HS
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2020;77(13):2483-2496
Metabolic regulation of neurodifferentiation in the adult brain
Maffezzini C; Calvo-Garrido J; Wredenberg A; Freyer C
Editorial comment: NEUROLOGY. 2018;91(15):710-712
Chorea, psychosis, acanthocytosis, and prolonged survival associated with ELAC2 mutations
Paucar M; Pajak A; Freyer C; Bergendal A; Dory M; Laffita-Mesa JM; Stranneheim H; Lagerstedt-Robinson K; Savitcheva I; Walker RH; Wedell A; Wredenberg A; Svenningsson P
Thesis / dissertation: 2007
Mitochondrial dysfunction in ageing and degenerative disease
Wredenberg, Anna

Employments

Professor/Specialist Physician, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2024-

Degrees and Education

Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2007
University Medical Degree, Karolinska Institutet, 2004
Bachelor Of Science In Physiotherapy, Karolinska Institutet, 1996

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