Onur Dagliyan

Onur Dagliyan

Assistant Professor
Visiting address: Solnavägen 9, 17177 Stockholm
Postal address: C2 Medicinsk biokemi och biofysik, C2 Molekylär neurobiologi Dagliyan, 171 77 Stockholm
Part of:

About me

  • Title: Assistant Professor

    Education & Training
    Research fellow in the laboratory of Michael Greenberg, Harvard Medical School, Boston, USA. Specialization: Molecular neurobiology
    Ph.D. in Biochemistry and Biophysics, UNC School of Medicine, Chapel Hill, USA. Specialization: Protein signaling and engineering
    B.S, and M.S. in Chemical and Biological Engineering, Koç University, Istanbul. Specialization: Machine learning, drug screening, molecular clock


    Grants&Awards:
    European Research Council (ERC) Starting Grant
    Swedish Research Council (Vetenskapsrådet) Svenska Sällskapet för Medicinsk Forskning (SSMF)
    The Swedish Brain Foundation (Hjärnfonden)
    The Strategic Research Area Neuroscience (StratNeuro)
    Karolinska Institutet Allocation GrantGoldenson Fellow 2020
    William Randolph Hearst Fund 2019-2020
    Alice and Joseph Brooks Postdoctoral Fellowship 2017-2018
    Advanced imaging certificate from Max Planck Institute of Neuroscience 2017
    UNC Lineberger Graduate Fellow of the Year 2014
    Howard Hughes Medical Institute Predoctoral Fellowship 2012-2015
    National Science Foundation- Materials Computation Center Travel Award 2012
    Director’s Award from the Biological and Biomedical Sciences Program, UNC 2010

Research

Teaching

  • Lecturer, “Neuronal circuits for appetite, food intake and satiety“, Karolinska  Institutet, 2022-
    Lecturer, “Protein Structure“, Karolinska Institutet, 2022-
    Lecturer, “DNA and RNA Structure“, Karolinska Institutet, 2022-
    Lecturer, “Introduction to biochemistry: Metabolism“, Karolinska
    Institutet, 2022-
    Teaching assistant, Macromolecular Equilibria course, 2012
    Teaching assistant, Chemical and Biological Engineering Senior Project
    course, 2009
    Teaching assistant, Process Design course, 2008

Articles

All other publications

Grants

  • Swedish Research Council
    1 January 2022 - 31 December 2025
    Upon the arrival of stimuli with new experiences, neuronal circuits regulate a large set of molecular adaptation programs at the DNA, RNA, and protein levels to store the necessary information and to perform computations. Many of these molecular events have been shown to be involved in the excitation of neuronal circuits responsible for a particular behavior, learning ability, and memory. However an activated neuronal circuit has to be balanced with inhibitory events, and the molecular mechanisms of such inhibition are mostly unknown. This excitatory-inhibitory balance is particularly important to develop innovative therapeutic approaches for brain disorders including epilepsy, depression, schizophrenia, autism, and learning disorders. The two-third of my research program here will unravel two molecular mechanisms by which the inhibitory arm of the excitatory-inhibitory balance is established. The last part of the research program will focus on the development of technologies that enable the building of causal links between the spatiotemporal role of a protein and neuronal circuits. Overall this research program will allow us to better understand sensory-experience dependent circuit modulations at the molecular level and will pave the way to develop new therapeutic approaches for brain disorders.

Employments

  • Research Fellow, Neurobiology, Department of Neurobiology, Harvard Medical School, 2016-
  • Assistant Professor, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2022-2028

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