Marcus Buggert
Assistant Professor | Docent
E-mail: marcus.buggert@ki.se
Visiting address: Alfred Nobels allé 8, plan 7, 14152 Huddinge
Postal address: H7 Medicin, Huddinge, H7 CIM Buggert, 171 77 Stockholm
About me
- Docent and group leader at KI. Research focus on cell-mediated immunity to
viral infections and cancer.
Master in Biomedicine at KI, 2004-2009. PhD studies at KI, 2010-2014. Post
doc at University of Pennsylvania, USA, 2014-2017. Assistant Professor at KI,
2018-. Group leader at KI, 2019-. Docent at KI, 2021-
Research
- The Marcus Buggert research group is conducting research at Center for
Infections Medicine (CIM) in Huddinge. [1]
Our group conducts research on cell-mediated immunity. More specifically, we
are interested in understanding how memory T cells recognize and eliminates
viral infections and tumors. T cells are critical for immune control of
multiple viral infections and also represent a major cellular target of
immune checkpoint therapies that have entirely revolutionized the treatment
outcome in cancer care. However, much of our current understanding of memory
T cell functions are derived from studies of peripheral blood in humans. With
emerging data from us and others demonstrating that most memory T cells in
tissues are non-circulating resident cells, there is a need to better assess
how, where and what type of T cells that orchestrate immunity at barrier
sites.
The group focuses our work on many of these concepts with the overall aims to
i) study the heterogeneity of circulating and resident memory T cells in
human organ donors, ii) identify alternative functions of memory T cells in
human tissues, and iii) understand how memory T cells maintain control of
tumors and viral infections, such as HIV and SARS-CoV-2.
[1] https://ki.se/en/medh/marcus-buggert-group-human-memory-cd8-t-cells
Articles
- Journal article: IMMUNITY. 2024;57(9):2007-2009
- Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2024;44(5):116
- Article: GENES AND IMMUNITY. 2024;25(2):168-169
- Article: NATURE COMMUNICATIONS. 2024;15(1):1752
- Article: CELL HOST AND MICROBE. 2024;32(2):156-161.e3
- Article: JOURNAL OF IMMUNOLOGY. 2024;212(3):389-396
- Article: NPJ BIOFILMS AND MICROBIOMES. 2023;9(1):104
- Article: SCIENCE IMMUNOLOGY. 2023;8(90):eadh0687
- Article: NATURE COMMUNICATIONS. 2023;14(1):6527
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(6):1075-1082
- Article: JOURNAL OF HEMATOLOGY. 2023;12(4):170-175
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2023;15(704):eadg9452
- Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2023;80(7):189
- Article: CELL HOST AND MICROBE. 2023;31(6):928-936.e4
- Article: NATURE COMMUNICATIONS. 2023;14(1):2952
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):223.13
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1):63.22
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):226.09
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):75.20
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):75.16
- Journal article: CYTOTHERAPY. 2023;25(6):s237-s238
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(12):e2220320120
- Article: NATURE COMMUNICATIONS. 2023;14(1):1438
- Article: RESPIRATORY RESEARCH. 2023;24(1):62
- Journal article: JOURNAL OF VIRUS ERADICATION. 2022;8:100274
- Article: NATURE COMMUNICATIONS. 2022;13(1):6436
- Article: JOURNAL OF INFECTIOUS DISEASES. 2022;226(8):1428-1440
- Article: CELLS. 2022;11(19):3142
- Article: IMMUNITY. 2022;55(9):1732-1746.e5
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(6):1130-1136
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195
- Article: MOLECULAR MEDICINE. 2022;28(1):54
- Journal article: JOURNAL OF IMMUNOLOGY. 2022;208(1):169.16
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(4):716-727
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(3):503-510
- Article: NATURE MEDICINE. 2022;28(3):472-476
- Article: MED. 2022;3(2):137-153.e3
- Article: MOLECULAR MEDICINE. 2022;28(1):20
- Article: LEUKEMIA. 2022;36(2):476-481
- Journal article: NATURE MEDICINE. 2022
- Article: METHODS IN MOLECULAR BIOLOGY. 2022;2574:209-219
- Article: FRONTIERS IN IMMUNOLOGY. 2022;13:834862
- Article: FRONTIERS IN IMMUNOLOGY. 2022;13:896242
- Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1079995
- Article: SCIENCE IMMUNOLOGY. 2021;6(64):eabk0894
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2021;13(599):eabb3107
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(11):e2016580118
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
- Article: FRONTIERS IN IMMUNOLOGY. 2021;12:744530
- Article: PLOS ONE. 2021;16(9):e0258041
- Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
- Article: CELL. 2020;183(7):1946-1961.e15
- Article: SCIENCE IMMUNOLOGY. 2020;5(53):eabe8063
- Article: CELL. 2020;183(1):158-168.e14
- Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
- Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
- Journal article: JOURNAL OF HEPATOLOGY. 2020;73:s630-s631
- Journal article: JOURNAL OF HEPATOLOGY. 2020;73:s576
- Article: SCIENCE IMMUNOLOGY. 2020;5(49):eaba7918
- Article: JOURNAL OF VIROLOGY. 2020;94(14):e02128-e02119
- Journal article: JOURNAL OF IMMUNOLOGY. 2020;204(1_Supplement):86.46
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(523):eaax4077
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2019;129(8):3185-3200
- Article: JOURNAL OF INFECTIOUS DISEASES. 2019;219(11):1749-1754
- Journal article: JOURNAL OF IMMUNOLOGY. 2019;202(1_Supplement):51.5
- Journal article: JOURNAL OF IMMUNOLOGY. 2019;202(1_Supplement):189.7
- Journal article: JOURNAL OF IMMUNOLOGY. 2019;202(1_Supplement):121.16
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(49):E11513-E11522
- Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(137)
- Journal article: JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(137)
- Article: JOURNAL OF INFECTIOUS DISEASES. 2018;218(3):453-465
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2018;215(6):1531-1542
- Article: SCIENCE IMMUNOLOGY. 2018;3(24):eaar4526
- Journal article: JOURNAL OF IMMUNOLOGY. 2018;200(1_Supplement):120.12
- Article: JCI INSIGHT. 2018;3(7):98487
- Article: PLOS PATHOGENS. 2018;14(4):e1006973
- Article: FRONTIERS IN IMMUNOLOGY. 2018;9:19
- Article: CELL REPORTS. 2017;21(12):3458-3470
- Journal article: JOURNAL OF VIRUS ERADICATION. 2017;3:32
- Journal article: JOURNAL OF IMMUNOLOGY. 2017;198(1_Supplement):78.25
- Journal article: JOURNAL OF IMMUNOLOGY. 2017;198(1_Supplement):152.7
- Article: JCI INSIGHT. 2017;2(8):92943
- Article: TRANSLATIONAL CANCER RESEARCH. 2017;6:S65-S67
- Article: SCIENTIFIC REPORTS. 2017;7:40354
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2017;214(1):91-106
- Article: AIDS. 2016;30(16):2415-2426
- Article: PLOS PATHOGENS. 2016;12(8):e1005805
- Article: CLINICAL IMMUNOLOGY. 2015;161(2):180-189
- Article: PLOS PATHOGENS. 2015;11(8):e1005072
- Article: FRONTIERS IN IMMUNOLOGY. 2015;6:196
- Article: PLOS ONE. 2015;10(9):e0137635
- Article: CYTOMETRY. PART A : THE JOURNAL OF THE INTERNATIONAL SOCIETY FOR ANALYTICAL CYTOLOGY. 2014;85A(11):969-977
- Article: PLOS PATHOGENS. 2014;10(7):e1004251
- Article: JOURNAL OF IMMUNOLOGY. 2014;192(10):4685-4696
- Article: JOURNAL OF IMMUNOLOGY. 2014;192(5):2099-2108
- Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2013;29(3):602-612
- Article: JOURNAL OF VIROLOGY. 2012;86(18):9802-9816
- Article: PLOS ONE. 2012;7(7):e39874
- Article: JOURNAL OF IMMUNOLOGY. 2010;184(9):5383-5391
- Journal article:Reinvigoration of Progenitor-Exhausted CD8 T Cells by anti-CTLA-4 Contributes to the Sustained Activity of Combination Checkpoint Blockade
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All other publications
- Letter: HAEMATOLOGICA. 2024;109(2):646-651
- Preprint: BIORXIV. 2024
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;98(6):e13340
- Corrigendum: NATURE IMMUNOLOGY. 2023;24(10):1778
- Review: NATURE IMMUNOLOGY. 2023;24(10):1616-1627
- Corrigendum: NATURE IMMUNOLOGY. 2023;24(9):1591
- Editorial comment: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2023;220(7):e20230550
- Review: NATURE IMMUNOLOGY. 2023;24(7):1076-1086
- Meeting abstract: JOURNAL OF IMMUNOLOGY. 2023;210(1):59.47
- Preprint: RESEARCH SQUARE. 2023
- Preprint: RESEARCH SQUARE. 2023
- Preprint: RESEARCH SQUARE. 2023
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:241-242
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Editorial comment: FRONTIERS IN IMMUNOLOGY. 2023;14:1159452
- Conference publication: CYTOTHERAPY. 2023;25(6):S237-S238
- Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S169
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Letter: BLOOD. 2022;140(22):2403-2407
- Editorial comment: NATURE REVIEWS IMMUNOLOGY. 2022;22(9):533
- Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(4):e13153
- Review: MUCOSAL IMMUNOLOGY. 2022;15(3):389-397
- Preprint: BIORXIV. 2022
- Preprint: RESEARCH SQUARE. 2022
- Review: SEMINARS IN IMMUNOLOGY. 2021;55:101505
- Conference publication: JOURNAL OF IMMUNOLOGY. 2021;206:26.12
- Conference publication: CYTOTHERAPY. 2021;23(5):S90
- Preprint: SSRN ELECTRONIC JOURNAL. 2021
- Editorial comment: NATURE IMMUNOLOGY. 2021;22(1):8-9
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:95
- Conference publication: ANNALS OF ONCOLOGY. 2020;31:S1426
- Preprint: MEDRXIV. 2020
- Preprint: BIORXIV. 2020
- Editorial comment: SCIENCE IMMUNOLOGY. 2020;5(50):eabd3638
- Preprint: MEDRXIV. 2020
- Preprint: BIORXIV. 2020
- Conference publication: ZEITSCHRIFT FUR GASTROENTEROLOGIE. 2020;58(01):e38
- Conference publication: JOURNAL OF HEPATOLOGY. 2020;73:S630-S631
- Conference publication: JOURNAL OF IMMUNOLOGY. 2020;204(1)
- Conference publication: JOURNAL OF HEPATOLOGY. 2020;73:S576
- Preprint: BIORXIV. 2019
- Review: CURRENT OPINION IN HIV AND AIDS. 2019;14(2):93-99
- Conference publication: JOURNAL OF IMMUNOLOGY. 2019;202(1)
- Conference publication: JOURNAL OF IMMUNOLOGY. 2018;200(1)
- Review: FRONTIERS IN IMMUNOLOGY. 2018;9:1602
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):318
- Conference publication: JOURNAL OF IMMUNOLOGY. 2017;198(1)
- Conference publication: JOURNAL OF IMMUNOLOGY. 2017;198(1)
- Conference publication: JOURNAL OF CLINICAL IMMUNOLOGY. 2017;37(2):230
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):288-289
- Conference publication: JOURNAL OF IMMUNOLOGY. 2016;196:146.4
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2016;32:307
- Review: CELLULAR IMMUNOLOGY. 2015;298(1-2):126-133
- Thesis / dissertation: 2014
- Conference publication: IMMUNOLOGY. 2014;143:108
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2013;77(4):325
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2011;27(10):A88
- Conference publication: 2010;:658-659
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Grants
- Swedish Research Council1 December 2023 - 30 November 2026
- Swedish Research Council1 January 2023 - 31 December 2027
- Swedish Research Council1 January 2023 - 31 December 2027
- Swedish Research Council1 January 2023 - 31 December 2025
- Swedish Research Council1 December 2022 - 31 December 2026
- Swedish Research Council1 December 2022 - 30 November 2025
- Deutsche Forschungsgemeinschaft1 January 2022 - 31 December 2024
- Swedish Research Council1 December 2021 - 30 November 2024
- Swedish Research Council1 December 2021 - 30 November 2025
- Swedish Research Council1 June 2021 - 31 May 2025
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2021
- Swedish Research Council1 January 2021 - 31 December 2023
- Swedish Research Council1 January 2019 - 31 December 2022
- Define the origin and subset of PD-1+ CD8+ T cells responding to cancer immunotherapySwedish Cancer Society1 January 2019
- Swedish Research Council1 January 2015 - 31 December 2017
Employments
- Assistant Professor, Department of Medicine, Huddinge, Karolinska Institutet, 2018-2026
Degrees and Education
- Docent, Karolinska Institutet, 2021
- Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2014
News from KI
Events from KI
News from external media
- KNUT AND ALICE WALLENBERG FOUNDATION. 2023
- KNUT OCH ALICE WALLENBERGS STIFTELSE. 2023