Marcus Buggert

Marcus Buggert

Assistant Professor | Docent
Visiting address: Alfred Nobels allé 8, plan 7, 14152 Huddinge
Postal address: H7 Medicin, Huddinge, H7 CIM Buggert, 171 77 Stockholm

About me

  • Docent and group leader at KI. Research focus on cell-mediated immunity to
    viral infections and cancer.
    Master in Biomedicine at KI, 2004-2009. PhD studies at KI, 2010-2014. Post
    doc at University of Pennsylvania, USA, 2014-2017. Assistant Professor at KI,
    2018-. Group leader at KI, 2019-. Docent at KI, 2021-

Research

  • The Marcus Buggert research group is conducting research at Center for
    Infections Medicine (CIM) in Huddinge. [1]
    Our group conducts research on cell-mediated immunity. More specifically, we
    are interested in understanding how memory T cells recognize and eliminates
    viral infections and tumors. T cells are critical for immune control of
    multiple viral infections and also represent a major cellular target of
    immune checkpoint therapies that have entirely revolutionized the treatment
    outcome in cancer care. However, much of our current understanding of memory
    T cell functions are derived from studies of peripheral blood in humans. With
    emerging data from us and others demonstrating that most memory T cells in
    tissues are non-circulating resident cells, there is a need to better assess
    how, where and what type of T cells that orchestrate immunity at barrier
    sites.
    The group focuses our work on many of these concepts with the overall aims to
    i) study the heterogeneity of circulating and resident memory T cells in
    human organ donors, ii) identify alternative functions of memory T cells in
    human tissues, and iii) understand how memory T cells maintain control of
    tumors and viral infections, such as HIV and SARS-CoV-2.
    [1] https://ki.se/en/medh/marcus-buggert-group-human-memory-cd8-t-cells

Articles

All other publications

Employments

  • Assistant Professor, Department of Medicine, Huddinge, Karolinska Institutet, 2018-2026

Degrees and Education

  • Docent, Karolinska Institutet, 2021
  • Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2014

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