Ulrika Marklund
About me
My major research interest has always been centered around the development and function of neural cell types. During my PhD, I studied transcriptional determinants of specific neurons including the dopaminergic and serotonergic cells of the brain. I thereafter transitioned my research focus to the “Brain in the gut” – the Enteric Nervous System, during a postdoc at National Institute for Medical Research in Mill Hill, London, UK. Since 2013, I have led my own research group at the Department of Medical Biochemistry and Biophysics.
Research
My research team focuses on neural cell diversity in the Enteric Nervous System (ENS). By determining the variety of ENS cell subtypes, the functions they normally serve and their developmental specification we aim to improve diagnostic and therapeutic principles for gut disorders. The lab addresses these basic but critical questions by transcriptome analysis coupled with viral-based activity/gene manipulations primarily using the mouse model.
Articles
- Article: NATURE NEUROSCIENCE. 2024;27(12):2267-2268
- Article: STEM CELL REPORTS. 2021;16(11):2718-2735
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(6):145837
- Article: NATURE NEUROSCIENCE. 2021;24(1):34-46
- Article: FRONTIERS IN MOLECULAR NEUROSCIENCE. 2019;12:6
- Article: CELL. 2018;174(4):999-1014.e22
- Article: ELIFE. 2018;7:e34465
- Article: GASTROENTEROLOGY. 2018;154(3):624-636
- Article: SCIENCE. 2017;357(6346):46
- Article: JOURNAL OF NEUROSCIENCE. 2016;36(15):4339-4350
- Article: SCIENCE. 2014;345(6192):82-87
- Article: STEM CELLS AND DEVELOPMENT. 2014;23(1):5-15
- Article: DEVELOPMENT. 2010;137(23):4051-4060
- Article: JOURNAL OF CELL SCIENCE. 2010;123(17):2931-2942
- Article: DEVELOPMENT. 2010;137(3):437-445
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(18):7613-7618
- Article: CELL. 2006;124(2):393-405
- Article: NATURE NEUROSCIENCE. 2003;6(9):933-938
All other publications
- Editorial comment: NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY. 2022;19(2):85-86
- Doctoral thesis: 2008
Grants
- Swedish Research Council1 January 2023 - 31 December 2027
- Swedish Research Council1 January 2021 - 31 December 2024
- Knut and Alice Wallenberg Foundation1 January 2020
- Swedish Research Council1 January 2017 - 31 December 2020
- Swedish Research Council1 January 2013 - 31 December 2016
Employments
- Principal Researcher, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2022-
Degrees and Education
- Docent, Karolinska Institutet, 2024
- Degree Of Doctor Of Philosophy, Department of Cell and Molecular Biology, Karolinska Institutet, 2008