Pauliina Damdimopoulou
About me
With over 15 years of experience in endocrinology, reproductive biology and toxicology, I lead a research group at Karolinska Institutet that investigates the effects of chemicals on female fertility. My ambition is to generate evidence-based information on the risks of chemical exposures and pharmaceutical treatments to human ovaries and oocytes, and to thereby contribute to the development of a chemically safer society.
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I co-lead the Environmental Endocrinology Focus Area of the European Society of Endocrinology,
- In addition, I teach and supervise students at various levels, participate in university administration, and engage in stakeholder activities. I have received multiple grants and honors for my research, have served as a scientific expert for national and international organizations, and I frequently present my work at international conferences.
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Research
I'm interested in studying the impact of pharmaceuticals and environmental chemicals on fertility in women, with a special focus on the ovary.
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The work of my research group focuses on several aims:
-we assess environmental exposures in women and study their associations with fertility
-we study the effects of gonadotoxic treatments, like chemotherapy, on ovaries
-we map the molecular and cellular composition of human ovaries across life
-we investigate how environmental and pharmaceutical exposures affect ovaries by using tissue culture models
-we develop new in vitro tools for predicting reproductive toxicity of chemicals.
Teaching
I'm a docent in endocrine physiology (2015, University of Turku, Finland) and toxicology (2021, Karolinska Institutet) with teaching experience in various MSc and PhD courses at different universities in Sweden and Finland. I have supervised several undergraduate students through their practical laboratory training, as well as MSc thesis projects. I have also served as the main supervisor for many PhD students, guiding them to successful graduations. I have formal training in higher education pedagogy, leadership, and the supervision of doctoral students.
Articles
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Journal article: NATURE COMMUNICATIONS. 2024;15(1):6989
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Article: TOXICOLOGY. 2024;505:153815
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Article: HUMAN REPRODUCTION OPEN. 2024;2024(3):hoae028
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Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2024;22(1):60
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Article: ENVIRONMENT INTERNATIONAL. 2024;187:108710
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Article: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 2024;41(4):1035-1055
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Article: NATURE REVIEWS ENDOCRINOLOGY. 2024;20(4):187-188
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Article: JOURNAL OF PROTEOME RESEARCH. 2024;23(1):238-248
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Article: OPEN RESEARCH EUROPE. 2024;4:68
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Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2023;578:112064
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Article: REPRODUCTIVE BIOMEDICINE ONLINE. 2023;47(4):103287
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Journal article: TOXICOLOGY LETTERS. 2023;384:s192-s193
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Article: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY. 2023;33(5):699-709
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Article: SEMINARS IN REPRODUCTIVE MEDICINE. 2023;41(05):190-199
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Article: ENVIRONMENT INTERNATIONAL. 2023;179:108141
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Article: REPRODUCTIVE TOXICOLOGY. 2023;119:108416
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Article: REPRODUCTIVE TOXICOLOGY. 2023;119:108393
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Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
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Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
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Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
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Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
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Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
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Journal article: ENDOCRINE ABSTRACTS. 2023
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Article: JOURNAL OF PROTEOME RESEARCH. 2023;22(4):1071-1079
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Article: TOXICOLOGY. 2023;485:153425
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Article: ENVIRONMENTAL RESEARCH. 2023;216(Pt 1):114447
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Article: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1126485
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Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(47):e2208886119
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Article: REPRODUCTIVE TOXICOLOGY. 2022;112:136-147
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Article: PHARMACEUTICS. 2022;14(6):1295
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Article: ENVIRONMENTAL RESEARCH. 2022;208:112626
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Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(9):4815
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Article: REPRODUCTIVE TOXICOLOGY. 2022;109:19-30
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Article: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 2022;39(4):905-918
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Article: SCIENCE. 2022;375(6582):eabe8244
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Article: MICROPLASTICS AND NANOPLASTICS. 2022;2(1):12
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Article: FRONTIERS IN ENDOCRINOLOGY. 2022;13:903505
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Article: TOXICOLOGY. 2021;464:153028
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Article: TOXICOLOGICAL SCIENCES. 2021;184(2):183-190
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Article: CHEMOSPHERE. 2021;283:131125
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Article: ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS. 2021;23(10):1578-1588
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Article: ENVIRONMENT INTERNATIONAL. 2021;155:106589
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Article: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM. 2021;35(5):101552
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Article: DEVELOPMENTAL DYNAMICS. 2020;249(12):1500-1513
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Article: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 2020;37(9):2137-2150
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Article: ENVIRONMENTAL HEALTH. 2020;19(1):67
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Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2020;4(Supplement_1):or31-or03
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Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2020;4(Suppl 1)OR31-03 Single-Cell Profiling of Adult Human Ovarian Cortex Reveals Six Main Cell Types but No Germline Stem Cells
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Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(9):E3215-3215
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Article: MOLECULAR HUMAN REPRODUCTION. 2020;26(4):256-268
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Article: NATURE COMMUNICATIONS. 2020;11(1):1147
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Article: HUMAN REPRODUCTION. 2019;34(11):2297-2310
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Article: HUMAN REPRODUCTION. 2019;34(9):1674-1685
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Article: REPRODUCTIVE TOXICOLOGY. 2019;87:32-41
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Article: SCIENTIFIC REPORTS. 2019;9(1):8411
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Article: SCIENTIFIC REPORTS. 2019;9(1):6424
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Article: ENVIRONMENT INTERNATIONAL. 2019;124:482-492
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Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2018;478:77-83
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Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2018;338:73-82
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Article: SCIENTIFIC REPORTS. 2017;7(1):5317
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Article: ENDOCRINOLOGY. 2016;157(10):3719-3730
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Article: BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY. 2016;31:2-12
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Article: CHEMICO-BIOLOGICAL INTERACTIONS. 2015;231:44-52
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Article: BIOMATERIALS. 2014;35(30):8496-8502
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Article: ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2014;48(18):10919-10928
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Article: NATURE COMMUNICATIONS. 2014;5:3195
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Article: FASEB JOURNAL. 2013;27(4):1342-1350
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Article: TOXICOLOGICAL SCIENCES. 2012;127(1):66-75
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Article: JOURNAL OF NUTRITION. 2011;141(9):1583-1589
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Article: TOXICOLOGY LETTERS. 2011;202(2):75-84
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Article: PLOS ONE. 2011;6(8):e23048
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Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2010;118(10):1389-1394
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Article: AMERICAN JOURNAL OF PATHOLOGY. 2010;176(3):1443-1451
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Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1793(10):1588-1596
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Article: MOLECULAR NUTRITION & FOOD RESEARCH. 2009;53(8):996-1006
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Article: ENDOCRINOLOGY. 2007;148(10):4875-4886
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Article: REPRODUCTIVE TOXICOLOGY. 2007;23(3):397-406
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Article: PEDIATRIC RESEARCH. 2006;59(3):412-417
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Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2004;813(1-2):303-312
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All other publications
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Conference publication: TOXICOLOGY LETTERS. 2023;384:s77-S80
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Editorial comment: STEM CELLS. 2023;41(2):105-110
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Letter: STEM CELLS. 2023;41(2):205-206
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Conference publication: TOXICOLOGY LETTERS. 2023;384:S77
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Conference publication: TOXICOLOGY LETTERS. 2023;384:S192-S193
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Conference publication: HUMAN REPRODUCTION. 2023;38
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Conference publication: HUMAN REPRODUCTION. 2023;38
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Conference publication: HUMAN REPRODUCTION. 2023;38
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Conference publication: HUMAN REPRODUCTION. 2023;38
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Conference publication: HUMAN REPRODUCTION. 2023;38
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Conference publication: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102:65
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Conference publication: TOXICOLOGY LETTERS. 2022;368:S22
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Conference publication: TOXICOLOGY LETTERS. 2022;368:S178
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Conference publication: TOXICOLOGY LETTERS. 2022;368:S86
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Conference publication: TOXICOLOGY LETTERS. 2021;350:S169-S170
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Conference publication: TOXICOLOGY LETTERS. 2021;350:S48-S49
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Conference publication: REPRODUCTION IN DOMESTIC ANIMALS. 2021;56:7-8
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Review: ARCHIVES OF TOXICOLOGY. 2020;94(10):3359-3379
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Editorial comment: OBSTETRICAL & GYNECOLOGICAL SURVEY. 2020;75(6):354-355
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Letter: HUMAN REPRODUCTION. 2020;35(5):1249-1251
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Review: UPSALA JOURNAL OF MEDICAL SCIENCES. 2020;125(2):85-94
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Review: HORMONE RESEARCH IN PAEDIATRICS. 2020;93(11-12):599-608
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Review: HUMAN REPRODUCTION UPDATE. 2019;25(6):777-801
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Preprint: BIORXIV. 2019
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Conference publication: TOXICOLOGY LETTERS. 2018;295:S63
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Preprint: BIORXIV. 2017
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Review: JOURNAL OF ENDOCRINOLOGY. 2016;228(2):R45-R56
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Editorial comment: OBSTETRICAL & GYNECOLOGICAL SURVEY. 2016;71(1):29-30
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Letter: NATURE MEDICINE. 2015;21(10):1116-1118
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Conference publication: TOXICOLOGY LETTERS. 2013;221:S168
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Conference publication: TOXICOLOGY LETTERS. 2012;211:S38
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Book chapter: HORMONE-DISRUPTIVE CHEMICAL CONTAMINANTS IN FOOD. 2011;p. 44-69
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Editorial comment: ENDOCRINOLOGY. 2011;152(7):2542-2545
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Review: EXS. 2009;99:289-323
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Review: GENES AND NUTRITION. 2006;1(3-4):143-158
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Corrigendum: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2006;98(2-3):179
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Published conference paper: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2005;93(2-5):209-219
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Grants
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Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2022 - 31 December 2025
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Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2021 - 31 December 2023
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Swedish Research Council1 January 2021 - 31 December 2023
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Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 December 2018 - 30 November 2022
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Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2018 - 31 December 2020
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Swedish Research Council1 January 2018 - 31 December 2019
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Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2016 - 31 December 2018
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Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2016 - 31 December 2018
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Swedish Research Council1 January 2010 - 31 December 2010
Employments
- Senior Lecturer, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2022-
- Postdoctoral researcher, R&D, Watchfrog (France), 2008-2010
Degrees and Education
- Docent, Karolinska Institutet, 2021