Pauliina Damdimopoulou
About me
With over 15 years of experience in endocrinology, reproductive biology and toxicology, I lead a research group at Karolinska Institutet that investigates the effects of chemicals on female fertility. My ambition is to generate evidence-based information on the risks of chemical exposures and pharmaceutical treatments to human ovaries and oocytes, and to thereby contribute to the development of a chemically safer society.
I co-lead the Environmental Endocrinology Focus Area of the European Society of Endocrinology,
- In addition, I teach and supervise students at various levels, participate in university administration, and engage in stakeholder activities. I have received multiple grants and honors for my research, have served as a scientific expert for national and international organizations, and I frequently present my work at international conferences.
Research
I'm interested in studying the impact of pharmaceuticals and environmental chemicals on fertility in women, with a special focus on the ovary.
The work of my research group focuses on several aims:
-we assess environmental exposures in women and study their associations with fertility
-we study the effects of gonadotoxic treatments, like chemotherapy, on ovaries
-we map the molecular and cellular composition of human ovaries across life
-we investigate how environmental and pharmaceutical exposures affect ovaries by using tissue culture models
-we develop new in vitro tools for predicting reproductive toxicity of chemicals.
Teaching
I'm a docent in endocrine physiology (2015, University of Turku, Finland) and toxicology (2021, Karolinska Institutet) with teaching experience in various MSc and PhD courses at different universities in Sweden and Finland. I have supervised several undergraduate students through their practical laboratory training, as well as MSc thesis projects. I have also served as the main supervisor for many PhD students, guiding them to successful graduations. I have formal training in higher education pedagogy, leadership, and the supervision of doctoral students.
Articles
- Article: ENVIRONMENT INTERNATIONAL. 2024;191:108960
- Article: REPRODUCTIVE TOXICOLOGY. 2024;128:108660
- Article: NATURE COMMUNICATIONS. 2024;15(1):6989
- Article: TOXICOLOGY. 2024;505:153815
- Article: HUMAN REPRODUCTION OPEN. 2024;2024(3):hoae028
- Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2024;22(1):60
- Article: ENVIRONMENT INTERNATIONAL. 2024;187:108710
- Article: NATURE REVIEWS ENDOCRINOLOGY. 2024;20(4):187-188
- Article: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 2024;41(4):1035-1055
- Article: JOURNAL OF PROTEOME RESEARCH. 2024;23(1):238-248
- Article: OPEN RESEARCH EUROPE. 2024;4:68
- Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2023;578:112064
- Article: REPRODUCTIVE BIOMEDICINE ONLINE. 2023;47(4):103287
- Journal article: TOXICOLOGY LETTERS. 2023;384:s192-s193
- Article: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY. 2023;33(5):699-709
- Article: ENVIRONMENT INTERNATIONAL. 2023;179:108141
- Article: SEMINARS IN REPRODUCTIVE MEDICINE. 2023;41(05):190-199
- Article: REPRODUCTIVE TOXICOLOGY. 2023;119:108416
- Article: REPRODUCTIVE TOXICOLOGY. 2023;119:108393
- Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
- Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
- Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
- Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
- Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
- Journal article: ENDOCRINE ABSTRACTS. 2023
- Article: JOURNAL OF PROTEOME RESEARCH. 2023;22(4):1071-1079
- Article: TOXICOLOGY. 2023;485:153425
- Article: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1126485
- Article: ENVIRONMENTAL RESEARCH. 2023;216(Pt 1):114447
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(47):e2208886119
- Article: REPRODUCTIVE TOXICOLOGY. 2022;112:136-147
- Article: PHARMACEUTICS. 2022;14(6):1295
- Article: ENVIRONMENTAL RESEARCH. 2022;208:112626
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(9):4815
- Article: REPRODUCTIVE TOXICOLOGY. 2022;109:19-30
- Article: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 2022;39(4):905-918
- Article: SCIENCE. 2022;375(6582):eabe8244
- Article: MICROPLASTICS AND NANOPLASTICS. 2022;2(1):12
- Article: FRONTIERS IN ENDOCRINOLOGY. 2022;13:903505
- Article: TOXICOLOGY. 2021;464:153028
- Article: TOXICOLOGICAL SCIENCES. 2021;184(2):183-190
- Article: CHEMOSPHERE. 2021;283:131125
- Article: ENVIRONMENTAL SCIENCES: PROCESSES AND IMPACTS. 2021;23(10):1578-1588
- Article: ENVIRONMENT INTERNATIONAL. 2021;155:106589
- Article: BEST PRACTICE AND RESEARCH: CLINICAL ENDOCRINOLOGY AND METABOLISM. 2021;35(5):101552
- Article: DEVELOPMENTAL DYNAMICS. 2020;249(12):1500-1513
- Article: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 2020;37(9):2137-2150
- Article: ENVIRONMENTAL HEALTH: A GLOBAL ACCESS SCIENCE SOURCE. 2020;19(1):67
- Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2020;4(Supplement_1):or31-or03
- Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2020;4(Suppl 1)OR31-03 Single-Cell Profiling of Adult Human Ovarian Cortex Reveals Six Main Cell Types but No Germline Stem Cells
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(9):E3215-3215
- Article: MOLECULAR HUMAN REPRODUCTION. 2020;26(4):256-268
- Article: NATURE COMMUNICATIONS. 2020;11(1):1147
- Article: HUMAN REPRODUCTION. 2019;34(11):2297-2310
- Article: HUMAN REPRODUCTION. 2019;34(9):1674-1685
- Article: REPRODUCTIVE TOXICOLOGY. 2019;87:32-41
- Article: SCIENTIFIC REPORTS. 2019;9(1):8411
- Article: SCIENTIFIC REPORTS. 2019;9(1):6424
- Article: ENVIRONMENT INTERNATIONAL. 2019;124:482-492
- Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2018;478:77-83
- Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2018;338:73-82
- Article: SCIENTIFIC REPORTS. 2017;7(1):5317
- Article: ENDOCRINOLOGY. 2016;157(10):3719-3730
- Article: BEST PRACTICE AND RESEARCH: CLINICAL OBSTETRICS AND GYNAECOLOGY. 2016;31:2-12
- Article: CHEMICO-BIOLOGICAL INTERACTIONS. 2015;231:44-52
- Article: BIOMATERIALS. 2014;35(30):8496-8502
- Article: ENVIRONMENTAL SCIENCE AND TECHNOLOGY. 2014;48(18):10919-10928
- Article: NATURE COMMUNICATIONS. 2014;5:3195
- Article: THE FASEB JOURNAL. 2013;27(4):1342-1350
- Article: TOXICOLOGICAL SCIENCES. 2012;127(1):66-75
- Article: JOURNAL OF NUTRITION. 2011;141(9):1583-1589
- Article: TOXICOLOGY LETTERS. 2011;202(2):75-84
- Article: PLOS ONE. 2011;6(8):e23048
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2010;118(10):1389-1394
- Article: AMERICAN JOURNAL OF PATHOLOGY. 2010;176(3):1443-1451
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1793(10):1588-1596
- Article: MOLECULAR NUTRITION AND FOOD RESEARCH. 2009;53(8):996-1006
- Article: ENDOCRINOLOGY. 2007;148(10):4875-4886
- Article: REPRODUCTIVE TOXICOLOGY. 2007;23(3):397-406
- Article: PEDIATRIC RESEARCH. 2006;59(3):412-417
- Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2004;813(1-2):303-312
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All other publications
- Conference publication: TOXICOLOGY LETTERS. 2023;384:s77-S80
- Editorial comment: STEM CELLS. 2023;41(2):105-110
- Letter: STEM CELLS. 2023;41(2):205-206
- Conference publication: TOXICOLOGY LETTERS. 2023;384:S77
- Conference publication: TOXICOLOGY LETTERS. 2023;384:S192-S193
- Conference publication: HUMAN REPRODUCTION. 2023;38
- Conference publication: HUMAN REPRODUCTION. 2023;38
- Conference publication: HUMAN REPRODUCTION. 2023;38
- Conference publication: HUMAN REPRODUCTION. 2023;38
- Conference publication: HUMAN REPRODUCTION. 2023;38
- Conference publication: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102:65
- Conference publication: TOXICOLOGY LETTERS. 2022;368:S22
- Conference publication: TOXICOLOGY LETTERS. 2022;368:S178
- Conference publication: TOXICOLOGY LETTERS. 2022;368:S86
- Conference publication: TOXICOLOGY LETTERS. 2021;350:S169-S170
- Conference publication: TOXICOLOGY LETTERS. 2021;350:S48-S49
- Conference publication: REPRODUCTION IN DOMESTIC ANIMALS. 2021;56:7-8
- Review: ARCHIVES OF TOXICOLOGY. 2020;94(10):3359-3379
- Editorial comment: OBSTETRICAL AND GYNECOLOGICAL SURVEY. 2020;75(6):354-355
- Letter: HUMAN REPRODUCTION. 2020;35(5):1252-1253
- Review: UPSALA JOURNAL OF MEDICAL SCIENCES. 2020;125(2):85-94
- Review: HORMONE RESEARCH IN PAEDIATRICS. 2020;93(11-12):599-608
- Review: HUMAN REPRODUCTION UPDATE. 2019;25(6):777-801
- Preprint: BIORXIV. 2019
- Conference publication: TOXICOLOGY LETTERS. 2018;295:S63
- Preprint: BIORXIV. 2017
- Review: JOURNAL OF ENDOCRINOLOGY. 2016;228(2):R45-R56
- Editorial comment: OBSTETRICAL AND GYNECOLOGICAL SURVEY. 2016;71(1):29-30
- Letter: NATURE MEDICINE. 2015;21(10):1116-1118
- Conference publication: TOXICOLOGY LETTERS. 2013;221:S168
- Conference publication: TOXICOLOGY LETTERS. 2012;211:S38
- Book chapter: HORMONE-DISRUPTIVE CHEMICAL CONTAMINANTS IN FOOD. 2011;p. 44-69
- Editorial comment: ENDOCRINOLOGY. 2011;152(7):2542-2545
- Review: EXS. 2009;99:289-323
- Review: GENES AND NUTRITION. 2006;1(3-4):143-158
- Corrigendum: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2006;98(2-3):179
- Published conference paper: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2005;93(2-5):209-219
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Grants
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2022 - 31 December 2025
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2021 - 31 December 2023
- Swedish Research Council1 January 2021 - 31 December 2023
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 December 2018 - 30 November 2022
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2018 - 31 December 2020
- Swedish Research Council1 January 2018 - 31 December 2019
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2016 - 31 December 2018
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2016 - 31 December 2018
- Swedish Research Council1 January 2010 - 31 December 2010
Employments
- Senior Lecturer, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2022-
- Postdoctoral researcher, R&D, Watchfrog (France), 2008-2010
Degrees and Education
- Docent, Karolinska Institutet, 2021