Elif Eroglu

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About me

Our lab aims to discover principles of tissue regeneration through curiosity-driven science projects.

Research

Adult heart is one of the least regenerative organs in the human body. My group studies aquatic salamanders that have a fascinating regenerative capacity to ask how heart function can be restored.

Articles

Article: NATURE CELL BIOLOGY. 2022;24(5):645-658
Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders
Eroglu E; Yen CYT; Tsoi Y-L; Witman N; Elewa A; Araus AJ; Wang H; Szattler T; Umeano CH; Sohlmer J; Goedel A; Simon A; Chien KR
Article: NATURE CELL BIOLOGY. 2022;24(5):659-671
Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors.
Poch CM; Foo KS; De Angelis MT; Jennbacken K; Santamaria G; Bähr A; Wang Q-D; Reiter F; Hornaschewitz N; Zawada D; Bozoglu T; My I; Meier A; Dorn T; Hege S; Lehtinen ML; Tsoi YL; Hovdal D; Hyllner J; Schwarz S; Sudhop S; Jurisch V; Sini M; Fellows MD; Cummings M; Clarke J; Baptista R; Eroglu E; Wolf E; Klymiuk N; Lu K; Tomasi R; Dendorfer A; Gaspari M; Parrotta E; Cuda G; Krane M; Sinnecker D; Hoppmann P; Kupatt C; Fritsche-Danielson R; Moretti A; Chien KR; Laugwitz K-L
Article: JCI INSIGHT. 2022;7(2):e152198
Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors
Tang CSM; Mononen M; Lam W-Y; Jin SC; Zhuang X; Garcia-Barcelo M-M; Lin Q; Yang Y; Sahara M; Eroglu E; Chien KR; Hong H; Tam PKH; Gruber PJ
Article: NATURE COMMUNICATIONS. 2021;12(1):5126
Amnion signals are essential for mesoderm formation in primates
Yang R; Goedel A; Kang Y; Si C; Chu C; Zheng Y; Chen Z; Gruber PJ; Xiao Y; Zhou C; Witman N; Leung C-Y; Chen Y; Fu J; Ji W; Lanner F; Niu Y; Chien K
Article: DEVELOPMENT. 2019;146(23):dev183400
Dynamics of activating and repressive histone modifications in Drosophila neural stem cell lineages and brain tumors
Abdusselamoglu MD; Landskron L; Bowman SK; Eroglu E; Burkard T; Kingston RE; Knoblich JA
Article: ELIFE. 2019;8:e46566
The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop
Abdusselamoglu MD; Eroglu E; Burkard TR; Knoblich JA
Article: CELL. 2014;156(6):1259-1273
SWI/SNF Complex Prevents Lineage Reversion and Induces Temporal Patterning in Neural Stem Cells
Eroglu E; Burkard TR; Jiang Y; Saini N; Homem CCF; Reichert H; Knoblich JA
Article: NATURE CELL BIOLOGY. 2011;13(9):1070-1075
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
Ten Berge D; Kurek D; Blauwkamp T; Koole W; Maas A; Eroglu E; Siu RK; Nusse R
Article: CELL STEM CELL. 2008;3(5):508-518
Wnt Signaling Mediates Self-Organization and Axis Formation in Embryoid Bodies
ten Berge D; Koole W; Fuerer C; Fish M; Eroglu E; Nusse R

All other publications

Editorial comment: NATURE CELL BIOLOGY. 2021;23(5):440-442
PHF7 directs cardiac reprogramming
Eroglu E; Schell JP; Chien KR
Editorial comment: CELL STEM CELL. 2018;22(6):787-789
Lnc'ed in to Cardiogenesis
Sahara M; Eroglu E; Chien KR
Editorial comment: DEVELOPMENTAL CELL. 2017;42(1):7-8
Heart Regeneration 4.0: Matrix Medicine
Eroglu E; Chien KR

Grants

ERC StG 2024
European Research Council
1 April 2025 - 1 April 2030
KID Grant, Karolinska Institute
3 June 2024 - 31 December 2028
Wallenberg Academy Fellow 2023
Knut och Alice Wallenbergs Stiftelse
1 June 2024 - 30 June 2029
EMBO New Venture Fellow
European Molecular Biology Organization
14 June 2023 - 31 July 2023
Åke Wibergs Stiftelse
2 January 2023 - 31 December 2024
Starting Grant
Swedish Research Council
1 January 2023 - 31 December 2027
Ming Wai Lau Center Seed Grant

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